DNA Vaccination Partially Protects against African Swine Fever Virus Lethal Challenge in the Absence of Antibodies

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Argilaguet, Jordi M ^a,f   Pérez Martín, Eva ^a,g   Nofrarías, Miquel ^a   Gallardo, Carmina ^b   Accensi, Francesc ^a,e   Lacasta, Anna ^a   Mora, Mercedes ^a   Ballester, Maria ^a   Galindo Cardiel, Ivan ^a   López Soria, Sergio ^a   Escribano, José M ^c   Reche, Pedro A ^d   Rodríguez, Fernando ^a  

^a CENTRE DE RECERCA EN SANITAT ANIMAL CRESA   (Spain)

^b Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria   (Spain)

^c INIA   (Spain)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^e UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^f UNIVERSITAT POMPEU FABRA   (Spain)

^g PLUM ISLAND ANIMAL DISEASE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; DNA VACCINE; GAMMA INTERFERON; PROTEIN P30; PROTEIN P54; UBIQUITIN; VIRUS ANTIBODY; VIRUS HEMAGGLUTININ;

AFRICAN SWINE FEVER; AFRICAN SWINE FEVER VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN PRESENTATION; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; COMPUTER ANALYSIS; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; DNA IMMUNIZATION; HUMORAL IMMUNITY; IN VIVO STUDY; LYMPHOCYTE COUNT; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMID; PROTECTION; SURVIVAL RATE; SWINE; VACCINE PRODUCTION; VIRUS STRAIN; VIRUS VIRULENCE;

AFRICAN SWINE FEVER; AFRICAN SWINE FEVER VIRUS; ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CELLS, CULTURED; DNA, VIRAL; INTERFERON-GAMMA; PLASMIDS; RECOMBINANT FUSION PROTEINS; SURVIVAL RATE; SWINE; T-LYMPHOCYTES, CYTOTOXIC; UBIQUITIN; VACCINATION; VACCINES, DNA; VACCINES, SYNTHETIC; VIRAL PROTEINS; VIRAL VACCINES;

AFRICAN SWINE FEVER VIRUS; ANIMALIA; SUIDAE;

EID: 84866839899     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040942     Document Type: Article

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