Measurements of vaccinia virus dissemination using whole body imaging: Approaches for predicting of lethality in challenge models and testing of vaccines and antiviral treatments

Methods in Molecular Biology

Volumn 890, Issue , 2012, Pages 161-176

  Zaitseva, Marina ^a   Kapnick, Senta ^a   Golding, Hana ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

Dryvax vaccine; Predictive models of lethality; Receiver Operating Characteristic curve analysis; Vaccinia virus; Whole body bioimaging

Indexed keywords

ANTIVIRUS AGENT; LUCIFERASE; VACCINIA VACCINE; DRYVAX VACCINE; FIREFLY LUCIFERASE; LUCIFERIN; SMALLPOX VACCINE; VIRUS ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BIOLUMINESCENCE; CONTROLLED STUDY; HUMAN; IMMUNOTHERAPY; LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEIVER OPERATING CHARACTERISTIC; VACCINIA; VACCINIA VIRUS; VIRUS LOAD; VIRUS REPLICATION; VIRUS TRANSMISSION; WHOLE BODY IMAGING; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; DRUG SCREENING; GENETICS; IMMUNOLOGY; LIVER; LUMINESCENCE; LUNG; METABOLISM; METHODOLOGY; NOSE CAVITY; PATHOLOGY; PHYSIOLOGY; REPORTER GENE; SPLEEN; VACCINATION; VIROLOGY;

ANIMALS; ANTIGENS, VIRAL; ANTIVIRAL AGENTS; AREA UNDER CURVE; DRUG EVALUATION, PRECLINICAL; FIREFLY LUCIFERIN; GENES, REPORTER; LIVER; LUCIFERASES, FIREFLY; LUMINESCENT MEASUREMENTS; LUNG; MICE; MICE, INBRED BALB C; NASAL CAVITY; ROC CURVE; SMALLPOX VACCINE; SPLEEN; VACCINATION; VACCINIA; VACCINIA VIRUS; WHOLE BODY IMAGING;

EID: 84866776877     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-876-4_10     Document Type: Article

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