Analysis of homoisoflavonoids in Caesalpinia digyna by HPLC-ESI-MS, HPLC and method validation

Natural Product Communications

Volumn 7, Issue 9, 2012, Pages 1189-1192

  Roy, Somendu K ^a   Srivastava, Amit ^a   Jachak, Sanjay M ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Caesalpinia digyna; Homoisoflavonoids; HPLC; HPLC ESI MS; Method validation

Indexed keywords

8 METHOXYBONDUCELLIN; ACETIC ACID; BONDUCELLIN; CAESALPINIA DIGYNA EXTRACT; EUCOMINE; HOMOISOFLAVONOID; INTRICATINOL; ISOBONDUCELLIN; ISOFLAVONOID; ISOINTRICATINOL; METHANOL; PLANT EXTRACT; UNCLASSIFIED DRUG; WATER;

ACCURACY; ARTICLE; CAESALPINIA; CAESALPINIA DIGYNA; DRUG IDENTIFICATION; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF DETECTION; PLANT ROOT; PRODUCT RECOVERY; QUALITY CONTROL; QUANTITATIVE ANALYSIS; RELIABILITY; VALIDATION PROCESS;

CAESALPINIA; CAESALPINIA DIGYNA;

EID: 84866769057     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x1200700922     Document Type: Article

References (13)

1. Anonymous.(1992) Wealth of India- A directory of Indian raw materials and industrial products. Council of Scientific and Industrial Research, New Delhi. Vol 3 C-Ci, 12-13.
2. Gautam R, Saklani A, Jachak SM. (2007) Indian medicinal plants as a source of antimycobacterial agents. Journal of Ethnopharmacology, 110, 200-234.
3. Srinivasan R, Chandrasekar MJN, Nanjan MJ, Suresh B. (2007). Antioxidant activity of Caesalpinia digyna root. Journal of Ethnopharmacology, 113, 284-291. (Pubitemid 47243784)
4. Singh U, Kunwar A, Srinivasan R, Nanjan MJ, Priyadarsini KI. (2009) Differential free radical scavenging activity and radioprotection of Caesalpinia digyna extracts and its active constituent. Journal of Radiation Research, 50, 425-433.
5. Chandiran IS, Swamy V, Kumar BP, Narayanan V. (2008) Hypoglycaemic and hypolipidemic activity of methanolic root extract of Caesalpinia digyna (Rottler) in streptozotocin-induced diabetic rats. Pharmacologyonline, 2, 781-789.
6. Roy SK, Agrahari UC, Gautam R, Srivastava A, Jachak SM. (2012) Isointricatinol, a new antioxidant homoisoflavonoid from the roots of Caesalpinia digyna Rottler. Natural Product Research, 26, 690-695.
7. Purushothaman KK, Kalyani K, Subramaniam K, Shanmughanathan SP. (1982) Structure of bonducellin-A new homoisoflavone from Caesalpinia bonducella. Indian Journal of Chemistry, 21B, 383-386.
8. Ata A, Gale EM, Samarasekera R. (2009) Bioactive chemical constituents of Caesalpinia bonduc (Fabaceae). Phytochemistry Letters, 2, 106-109.
9. Srinivas K, Koteswara-Rao Y, Mahender I, Das B, Rama-Krishna KVS, Hara-Kishore K, Murty USN. (2003) Flavanoids from Caesalpinia pulcherrima. Phytochemistry, 63, 789-793. (Pubitemid 36903592)
10. Chen P, Yang JS. (2007) Flavonolgalactosidecaffeate ester and homoisoflavones from Caesalpinia millettii HOOK. et ARN. Chemical and Pharmaceutical Bulletin, 55, 655-657. (Pubitemid 46570850)
11. (a) Zhao P, Iwamoto Y, Kouno I, Egami Y, Yamamoto H. (2004) Stimulating the production of homoisoflavonoids in cell suspension cultures of Caesalpinia pulcherrima using cork tissue. Phytochemistry, 65, 2455-2461;
12. (b) Bezabih M, Famuyiwa SO, Abegaz BM. (2009) HPLC analysis and NMR identification of homoisoflavonoids and stilbenoids from the inter-bulb surfaces of Scilla nervosa. Natural Product Communications, 4, 1367-1370.
13. ICH-Q2 (R1). (2005) Validation of analytical procedure: Text and Methodology. International Conference on Harmonization: Geneva (www.emea.europa.eu/pdfs/human/ich/038195en.pdf).