Innate and lymphocytic response of birch-allergic patients before and after sublingual immunotherapy

Allergy and Asthma Proceedings

Volumn 33, Issue 5, 2012, Pages 411-415

  Guida, Giuseppe ^a   Boita, Monica ^b   Scirelli, Tiziana ^b   Bommarito, Luisa ^b   Heffler, Enrico ^b   Badiu, Iuliana ^b   Bellone, Graziella ^b   Mietta, Sabrina ^b   Mistrello, Gianni ^c   Rolla, Giovanni ^b  

^a Birago di Vische Hospital   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c Lofarma SpA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 6; POLLEN ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BIRCH ALLERGY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DENDRITIC CELL; FEMALE; HAY FEVER; HUMAN; INNATE IMMUNITY; LYMPHOCYTE CULTURE; LYMPHOCYTE PROLIFERATION; MALE; POLLEN ALLERGY; SUBLINGUAL IMMUNOTHERAPY; T LYMPHOCYTE;

ADMINISTRATION, SUBLINGUAL; ADULT; ALLERGENS; ANTIGENS, PLANT; BETULA; COCULTURE TECHNIQUES; CYTOKINES; DENDRITIC CELLS; DESENSITIZATION, IMMUNOLOGIC; FEMALE; HUMANS; IMMUNITY, INNATE; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MALE; MIDDLE AGED; MONOCYTES; RHINITIS, ALLERGIC, SEASONAL; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TREATMENT OUTCOME;

EID: 84866760772     PISSN: 10885412     EISSN: 15396304     Source Type: Journal    
DOI: 10.2500/aap.2012.33.3588     Document Type: Article

References (23)

1. Imada M, Simons FE, Jay FT, and Hayglass KT. Allergen-stimulated interleukin-4 and interferon-gamma production in primary culture: responses of subjects with allergic rhinitis and normal controls. Immunology 85:373-380, 1995.
2. Jenmalm MC, Van Snick J, Cormont F, and Salman B. Allergen-induced Th1 and Th2 cytokine secretion in relation to specific allergen sensitization and atopic symptoms in children. Clin Exp Allergy 31:1528-1535, 2001. (Pubitemid 32939459)
3. Söderlund A, Gabrielsson S, Paulie S, et al. Allergen induced cytokine profiles in type I allergic individuals before and after immunotherapy. Immunol Lett 57:177-181, 1997. (Pubitemid 27319335)
4. Movérare R, Elfman L, Ståenheim G, et al. Study of the Th1/Th2 balance, including IL-10 production, in cultures of peripheral blood mononuclear cells from birch-pollen-allergic patients. Allergy 55:171-175, 2000. (Pubitemid 30106022)
5. Banchereau J, Briere F, Caux C, et al. Immunobiology of dendritic cells. Annu Rev Immunol 18:767-811, 2000. (Pubitemid 30365397)
6. Van den Heuvel MM, Vanhee DD, Postmus PE, et al. Functional and phenotypic differences of monocyte-derived dendritic cells from allergic and nonallergic patients. J Allergy Clin Immunol 101:90-95, 1998. (Pubitemid 28112886)
7. Angelini F, Pacciani V, Corrente S, et al. Dendritic cells modification during sublingual immunotherapy in children with allergic symptoms to house dust mites. World J Pediatr 7:24-30, 2011.
8. Bellinghausen I, Brand U, Knop J, and Saloga J. Comparison of allergen-stimulated dendritic cells from atopic and nonatopic donors dissecting their effect on autologous naive and memory T helper cells of such donors. J Allergy Clin Immunol 105:988-996, 2000. (Pubitemid 30324409)
9. De Wit D, Amraoui Z, Vincart B, et al. Helper T-cell responses elicited by Der p 1-pulsed dendritic cells and recombinant IL-12 in atopic and healthy subjects. J Allergy Clin Immunol 105:346-352, 2000. (Pubitemid 30109050)
10. Smole U, Balazs N, Hoffmann-Sommergruber K, et al. Differential T-cell responses and allergen uptake after exposure of dendritic cells to the birch pollen allergens Bet v 1.0101, Bet v 1.0401, and Bet v 1.1001. Immunobiology 215:903-909, 2010.
11. Casas R, Skarsvik S, Lindstrom A, et al. Impaired maturation of monocyte-derived dendritic cells from birch allergic individuals in association with birch-specific immune responses. Scand J Immunol 66:591-598, 2007. (Pubitemid 47609701)
12. Tversky JR, Le TV, Bieneman AP, et al. Human blood dendritic cells from allergic subjects have impaired capacity to produce interferon-alpha via Toll-like receptor 9. Clin Exp Allergy 38:781-788, 2008. (Pubitemid 351550669)
13. Novak N, and Allam JP. Mucosal dendritic cells in allergy and immunotherapy. Allergy 66(suppl 95):22-24, 2011.
14. Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 31:143-178, 2008.
15. Brozek JL, Bousquet J, Baena-Cagnani CE, et al. Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines: 2010 Revision. J Allergy Clin Immunol 126:466-476, 2010.
16. Leonardi S, Arena A, Bruno ME, et al. Olea sublingual allergoid immunotherapy administered with two different treatment regimens. Allergy Asthma Proc 31:e25-e29, 2010.
17. Bellinghausen I. Modification of the innate immune function of dendritic cells by allergen-specific immunotherapy. Clin Exp Allergy 40:12-14, 2010.
18. Tversky JR, Bieneman AP, Chichester KL, et al. Subcutaneous allergen immunotherapy restores human dendritic cell innate immune function. Clin Exp Allergy 40:94-102, 2010.
19. Ciprandi G, Tosca MA, and Marseglia GL. Sublingual immunotherapy mechanisms of action: The role of Th1 response. Int J Immunopathol Pharmacol 22(Suppl 4):9-12, 2009.
20. Bohle B, Kinaciyan T, Gerstmayr M, et al. Sublingual immunotherapy induces IL-10-producing T regulatory cells, allergen-specific T-cell tolerance, and immune deviation. J Allergy Clin Immunol 120:707-713, 2007. (Pubitemid 47320765)
21. Charbonnier AS, Hammad H, Gosset P, et al. Der p 1-pulsed myeloid and plasmacytoid dendritic cells from house dust mite-sensitized allergic patients dysregulate the T cell response. J Leukoc Biol 73:91-99, 2003. (Pubitemid 36125679)
22. Smole U, Wagner S, Balazs N, et al. Bet v 1 and its homologous food allergen Api g 1 stimulate dendritic cells from birch pollen-allergic individuals to induce different Th-cell polarization. Allergy 65:1388-1396, 2010.
23. Cosmi L, Santarlasci V, Angeli R, et al. Sublingual immunotherapy with Dermatophagoides monomeric allergoid down-regulates allergen-specific immunoglobulin E and increases both interferon-gamma-and interleukin-10- production. Clin Exp Allergy 36:261-272, 2006. (Pubitemid 43344707)