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Volumn 60, Issue 2, 2012, Pages 400-409

Porcine T-helper and regulatory T cells exhibit versatile mRNA expression capabilities for cytokines and co-stimulatory molecules

Author keywords

Cytokines; QPCR; Swine; T helper cells; Tregs

Indexed keywords

CD40 LIGAND; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 27; INTERLEUKIN 35; INTERLEUKIN 4; INTERLEUKIN 6; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84866755421     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.07.007     Document Type: Article
Times cited : (18)

References (39)
  • 1
    • 33947375136 scopus 로고    scopus 로고
    • Development of a microarray for studying porcine cytokine production in blood mononuclear cells and intestinal biopsies
    • Andersson M., Berg M., Fossum C., Jensen-Waern M. Development of a microarray for studying porcine cytokine production in blood mononuclear cells and intestinal biopsies. J Vet Med A Physiol Pathol Clin Med 2007, 54:161-168.
    • (2007) J Vet Med A Physiol Pathol Clin Med , vol.54 , pp. 161-168
    • Andersson, M.1    Berg, M.2    Fossum, C.3    Jensen-Waern, M.4
  • 2
    • 0026657068 scopus 로고
    • A monoclonal antibody recognising an epitope associated with pig interleukin-2 receptors
    • Bailey M., Stevens K., Bland P.W., Stokes C.R. A monoclonal antibody recognising an epitope associated with pig interleukin-2 receptors. J Immunol Methods 1992, 153:85-91.
    • (1992) J Immunol Methods , vol.153 , pp. 85-91
    • Bailey, M.1    Stevens, K.2    Bland, P.W.3    Stokes, C.R.4
  • 5
    • 79953289333 scopus 로고    scopus 로고
    • Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds
    • Chanput W., Mes J., Vreeburg R.A., Savelkoul H.F., Wichers H.J. Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds. Food Funct 2010, 1:254-261.
    • (2010) Food Funct , vol.1 , pp. 254-261
    • Chanput, W.1    Mes, J.2    Vreeburg, R.A.3    Savelkoul, H.F.4    Wichers, H.J.5
  • 6
    • 0037063987 scopus 로고    scopus 로고
    • Evaluation of cytokine gene expression in porcine spleen cells, peripheral blood mononuclear cells, and alveolar macrophages by competitive RT-PCR
    • Choi I.S., Collisson E.W., Maheswaran S.K., Yoo H.S. Evaluation of cytokine gene expression in porcine spleen cells, peripheral blood mononuclear cells, and alveolar macrophages by competitive RT-PCR. FEMS Immunol Med Microbiol 2002, 34:119-126.
    • (2002) FEMS Immunol Med Microbiol , vol.34 , pp. 119-126
    • Choi, I.S.1    Collisson, E.W.2    Maheswaran, S.K.3    Yoo, H.S.4
  • 7
    • 36549030784 scopus 로고    scopus 로고
    • The inhibitory cytokine IL-35 contributes to regulatory T-cell function
    • Collison L.W., Workman C.J., Kuo T.T., Boyd K., Wang Y., Vignali K.M., et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 2007, 450:566-569.
    • (2007) Nature , vol.450 , pp. 566-569
    • Collison, L.W.1    Workman, C.J.2    Kuo, T.T.3    Boyd, K.4    Wang, Y.5    Vignali, K.M.6
  • 9
    • 22744434397 scopus 로고    scopus 로고
    • Age, gender and litter-related variation in T-lymphocyte cytokine production in young pigs
    • De Groot J., Kruijt L., Scholten J.W., Boersma W.J., Buist W.G., Engel B., et al. Age, gender and litter-related variation in T-lymphocyte cytokine production in young pigs. Immunology 2005, 115:495-505.
    • (2005) Immunology , vol.115 , pp. 495-505
    • De Groot, J.1    Kruijt, L.2    Scholten, J.W.3    Boersma, W.J.4    Buist, W.G.5    Engel, B.6
  • 10
    • 28444494443 scopus 로고    scopus 로고
    • Quantitative simultaneous multiplex real-time PCR for the detection of porcine cytokines
    • Duvigneau J.C., Hartl R.T., Groiss S., Gemeiner M. Quantitative simultaneous multiplex real-time PCR for the detection of porcine cytokines. J Immunol Methods 2005, 306:16-27.
    • (2005) J Immunol Methods , vol.306 , pp. 16-27
    • Duvigneau, J.C.1    Hartl, R.T.2    Groiss, S.3    Gemeiner, M.4
  • 11
  • 12
    • 34347214467 scopus 로고    scopus 로고
    • Heparin and EDTA as anticoagulant differentially affect cytokine mRNA level of cultured porcine blood cells
    • Duvigneau J.C., Sipos W., Hartl R.T., Bayer M., Moldzio R., Stevenson L., et al. Heparin and EDTA as anticoagulant differentially affect cytokine mRNA level of cultured porcine blood cells. J Immunol Methods 2007, 324:38-47.
    • (2007) J Immunol Methods , vol.324 , pp. 38-47
    • Duvigneau, J.C.1    Sipos, W.2    Hartl, R.T.3    Bayer, M.4    Moldzio, R.5    Stevenson, L.6
  • 13
    • 0030612336 scopus 로고    scopus 로고
    • Molecular cloning and mRNA expression of porcine interleukin-12
    • Foss D.L., Murtaugh M.P. Molecular cloning and mRNA expression of porcine interleukin-12. Vet Immunol Immunopathol 1997, 57:121-134.
    • (1997) Vet Immunol Immunopathol , vol.57 , pp. 121-134
    • Foss, D.L.1    Murtaugh, M.P.2
  • 14
    • 77951947185 scopus 로고    scopus 로고
    • Transcriptome analysis of porcine PBMCs after in vitro stimulation by LPS or PMA/ionomycin using an expression array targeting the pig immune response
    • Gao Y., Flori L., Lecardonnel J., Esquerre D., Hu Z.L., Teillaud A., et al. Transcriptome analysis of porcine PBMCs after in vitro stimulation by LPS or PMA/ionomycin using an expression array targeting the pig immune response. BMC Genomics 2010, 11:292.
    • (2010) BMC Genomics , vol.11 , pp. 292
    • Gao, Y.1    Flori, L.2    Lecardonnel, J.3    Esquerre, D.4    Hu, Z.L.5    Teillaud, A.6
  • 15
    • 0033567957 scopus 로고    scopus 로고
    • IL-4-producing gamma delta T cells that express a very restricted TCR repertoire are preferentially localized in liver and spleen
    • Gerber D.J., Azuara V., Levraud J.P., Huang S.Y., Lembezat M.P., Pereira P. IL-4-producing gamma delta T cells that express a very restricted TCR repertoire are preferentially localized in liver and spleen. J Immunol 1999, 163:3076-3082.
    • (1999) J Immunol , vol.163 , pp. 3076-3082
    • Gerber, D.J.1    Azuara, V.2    Levraud, J.P.3    Huang, S.Y.4    Lembezat, M.P.5    Pereira, P.6
  • 16
    • 77949653161 scopus 로고    scopus 로고
    • Development, regulation and functional capacities of Th17 cells
    • Hirota K., Martin B., Veldhoen M. Development, regulation and functional capacities of Th17 cells. Semin Immunopathol 2010, 32:3-16.
    • (2010) Semin Immunopathol , vol.32 , pp. 3-16
    • Hirota, K.1    Martin, B.2    Veldhoen, M.3
  • 18
    • 39449127746 scopus 로고    scopus 로고
    • Phenotypic and functional characterisation of porcine CD4(+)CD25 (high) regulatory T cells
    • Käser T., Gerner W., Hammer S.E., Patzl M., Saalmüller A. Phenotypic and functional characterisation of porcine CD4(+)CD25 (high) regulatory T cells. Vet Immunol Immunopathol 2008, 122:153-158.
    • (2008) Vet Immunol Immunopathol , vol.122 , pp. 153-158
    • Käser, T.1    Gerner, W.2    Hammer, S.E.3    Patzl, M.4    Saalmüller, A.5
  • 19
    • 80053303854 scopus 로고    scopus 로고
    • Porcine regulatory T cells: mechanisms and T-cell targets of suppression
    • Käser T., Gerner W., Saalmüller A. Porcine regulatory T cells: mechanisms and T-cell targets of suppression. Dev Comp Immunol 2011, 35:1166-1172.
    • (2011) Dev Comp Immunol , vol.35 , pp. 1166-1172
    • Käser, T.1    Gerner, W.2    Saalmüller, A.3
  • 20
    • 77956057856 scopus 로고    scopus 로고
    • Peritoneal inflammation in pigs is associated with early mitochondrial dysfunction in liver and kidney
    • Kozlov A.V., Van Griensven M., Haindl S., Kehrer I., Duvigneau J.C., Hartl R.T., et al. Peritoneal inflammation in pigs is associated with early mitochondrial dysfunction in liver and kidney. Inflammation 2010, 33:295-305.
    • (2010) Inflammation , vol.33 , pp. 295-305
    • Kozlov, A.V.1    Van Griensven, M.2    Haindl, S.3    Kehrer, I.4    Duvigneau, J.C.5    Hartl, R.T.6
  • 21
    • 0035164360 scopus 로고    scopus 로고
    • Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: a role of CD40 in regulatory T cell development
    • Kumanogoh A., Wang X., Lee I., Watanabe C., Kamanaka M., Shi W., et al. Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: a role of CD40 in regulatory T cell development. J Immunol 2001, 166:353-360.
    • (2001) J Immunol , vol.166 , pp. 353-360
    • Kumanogoh, A.1    Wang, X.2    Lee, I.3    Watanabe, C.4    Kamanaka, M.5    Shi, W.6
  • 23
    • 0025064468 scopus 로고
    • Target cell lysis and IL-2 secretion by gamma/delta T lymphocytes after activation with bacteria
    • Munk M.E., Gatrill A.J., Kaufmann S.H. Target cell lysis and IL-2 secretion by gamma/delta T lymphocytes after activation with bacteria. J Immunol 1990, 145:2434-2439.
    • (1990) J Immunol , vol.145 , pp. 2434-2439
    • Munk, M.E.1    Gatrill, A.J.2    Kaufmann, S.H.3
  • 24
    • 3142708571 scopus 로고    scopus 로고
    • Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
    • Paust S., Lu L., McCarty N., Cantor H. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc Natl Acad Sci USA 2004, 101:10398-10403.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10398-10403
    • Paust, S.1    Lu, L.2    McCarty, N.3    Cantor, H.4
  • 25
    • 0021270302 scopus 로고
    • Preparation and characterization of monoclonal antibodies reactive with porcine PBL
    • Pescovitz M.D., Lunney J.K., Sachs D.H. Preparation and characterization of monoclonal antibodies reactive with porcine PBL. J Immunol 1984, 133:368-375.
    • (1984) J Immunol , vol.133 , pp. 368-375
    • Pescovitz, M.D.1    Lunney, J.K.2    Sachs, D.H.3
  • 26
    • 36849058725 scopus 로고    scopus 로고
    • Synergistic effects of IL-2, IL-12 and IL-18 on cytolytic activity, perforin expression and IFN-gamma production of porcine natural killer cells
    • Pintaric M., Gerner W., Saalmüller A. Synergistic effects of IL-2, IL-12 and IL-18 on cytolytic activity, perforin expression and IFN-gamma production of porcine natural killer cells. Vet Immunol Immunopathol 2008, 121:68-82.
    • (2008) Vet Immunol Immunopathol , vol.121 , pp. 68-82
    • Pintaric, M.1    Gerner, W.2    Saalmüller, A.3
  • 27
    • 34748835898 scopus 로고    scopus 로고
    • IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation
    • Puccetti P., Grohmann U. IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation. Nat Rev Immunol 2007, 7:817-823.
    • (2007) Nat Rev Immunol , vol.7 , pp. 817-823
    • Puccetti, P.1    Grohmann, U.2
  • 28
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • Rozen S., Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 2000, 132:365-386.
    • (2000) Methods Mol Biol , vol.132 , pp. 365-386
    • Rozen, S.1    Skaletsky, H.2
  • 29
    • 0023147371 scopus 로고
    • Monoclonal antibodies reactive with swine lymphocytes. II. Detection of an antigen on resting T cells down-regulated after activation
    • Saalmüller A., Jonjic S., Bühring H.J., Reddehase M.J., Koszinowski U.H. Monoclonal antibodies reactive with swine lymphocytes. II. Detection of an antigen on resting T cells down-regulated after activation. J Immunol 1987, 138:1852-1857.
    • (1987) J Immunol , vol.138 , pp. 1852-1857
    • Saalmüller, A.1    Jonjic, S.2    Bühring, H.J.3    Reddehase, M.J.4    Koszinowski, U.H.5
  • 30
    • 18844371714 scopus 로고    scopus 로고
    • + regulatory T cell activity: it takes (IL-) two to tango
    • + regulatory T cell activity: it takes (IL-) two to tango. Eur J Immunol 2005, 35:1336-1341.
    • (2005) Eur J Immunol , vol.35 , pp. 1336-1341
    • Scheffold, A.1    Hühn, J.2    Hofer, T.3
  • 31
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • Schmittgen T.D., Livak K.J. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 2008, 3:1101-1108.
    • (2008) Nat Protoc , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 32
    • 79955577237 scopus 로고    scopus 로고
    • Exploratory reference intervals on hematology and cellular immune system of multiparous large white sows
    • Sipos W., Duvigneau C.J., Hartl R.T., Schwendenwein I. Exploratory reference intervals on hematology and cellular immune system of multiparous large white sows. Vet Immunol Immunopathol 2011, 141:307-311.
    • (2011) Vet Immunol Immunopathol , vol.141 , pp. 307-311
    • Sipos, W.1    Duvigneau, C.J.2    Hartl, R.T.3    Schwendenwein, I.4
  • 33
    • 22144459727 scopus 로고    scopus 로고
    • Porcine dermatitis and nephropathy syndrome (PDNS) is associated with a systemic cytokine expression profile indicative of proinflammation and a Th1 bias
    • Sipos W., Duvigneau J.C., Pietschmann P., Schilcher F., Hofbauer G., Hartl R.T., et al. Porcine dermatitis and nephropathy syndrome (PDNS) is associated with a systemic cytokine expression profile indicative of proinflammation and a Th1 bias. Vet Immunol Immunopathol 2005, 107:303-313.
    • (2005) Vet Immunol Immunopathol , vol.107 , pp. 303-313
    • Sipos, W.1    Duvigneau, J.C.2    Pietschmann, P.3    Schilcher, F.4    Hofbauer, G.5    Hartl, R.T.6
  • 34
    • 25444485654 scopus 로고    scopus 로고
    • Leukocyte CD40L deficiency affects the CD25(+) CD4 T cell population but does not affect atherosclerosis
    • Smook M.L., Heeringa P., Damoiseaux J.G., Daemen M.J., de Winther M.P., Gijbels M.J., et al. Leukocyte CD40L deficiency affects the CD25(+) CD4 T cell population but does not affect atherosclerosis. Atherosclerosis 2005, 183:275-282.
    • (2005) Atherosclerosis , vol.183 , pp. 275-282
    • Smook, M.L.1    Heeringa, P.2    Damoiseaux, J.G.3    Daemen, M.J.4    de Winther, M.P.5    Gijbels, M.J.6
  • 35
    • 42149169184 scopus 로고    scopus 로고
    • Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target
    • Sojka D.K., Huang Y.H., Fowell D.J. Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target. Immunology 2008, 124:13-22.
    • (2008) Immunology , vol.124 , pp. 13-22
    • Sojka, D.K.1    Huang, Y.H.2    Fowell, D.J.3
  • 36
    • 78650872255 scopus 로고    scopus 로고
    • Porcine blood mononuclear cell cytokine responses to PAMP molecules: comparison of mRNA and protein production
    • Sorensen N.S., Skovgaard K., Heegaard P.M. Porcine blood mononuclear cell cytokine responses to PAMP molecules: comparison of mRNA and protein production. Vet Immunol Immunopathol 2011, 139:296-302.
    • (2011) Vet Immunol Immunopathol , vol.139 , pp. 296-302
    • Sorensen, N.S.1    Skovgaard, K.2    Heegaard, P.M.3
  • 37
    • 38348998603 scopus 로고    scopus 로고
    • Heme oxygenase-1 attenuates ovalbumin-induced airway inflammation by up-regulation of foxp3 T-regulatory cells, interleukin-10, and membrane-bound transforming growth factor-1
    • Xia Z.W., Xu L.Q., Zhong W.W., Wei J.J., Li N.L., Shao J., et al. Heme oxygenase-1 attenuates ovalbumin-induced airway inflammation by up-regulation of foxp3 T-regulatory cells, interleukin-10, and membrane-bound transforming growth factor-1. Am J Pathol 2007, 171:1904-1914.
    • (2007) Am J Pathol , vol.171 , pp. 1904-1914
    • Xia, Z.W.1    Xu, L.Q.2    Zhong, W.W.3    Wei, J.J.4    Li, N.L.5    Shao, J.6
  • 38
    • 0030035866 scopus 로고    scopus 로고
    • Preparation of monoclonal anti-porcine CD3 antibodies and preliminary characterization of porcine T lymphocytes
    • Yang H., Oura C.A., Kirkham P.A., Parkhouse R.M. Preparation of monoclonal anti-porcine CD3 antibodies and preliminary characterization of porcine T lymphocytes. Immunology 1996, 88:577-585.
    • (1996) Immunology , vol.88 , pp. 577-585
    • Yang, H.1    Oura, C.A.2    Kirkham, P.A.3    Parkhouse, R.M.4
  • 39
    • 77958611660 scopus 로고    scopus 로고
    • Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors
    • Zhu J., Paul W.E. Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. Immunol Rev 2010, 238:247-262.
    • (2010) Immunol Rev , vol.238 , pp. 247-262
    • Zhu, J.1    Paul, W.E.2


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