Surrogate decision makers' attitudes towards research decision making for critically ill patients

Intensive Care Medicine

Volumn 38, Issue 10, 2012, Pages 1616-1623

  Barrett, Kali A ^a   Ferguson, Niall D ^a   Athaide, Valerie ^b   Cook, Deborah J ^c,d   Friedrich, Jan O ^a,e   McDonald, Ellen ^c,d   Pinto, Ruxandra ^f   Smith, Orla M ^e,g   Stevenson, James ^a   Scales, Damon C ^a,f  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c MCMASTER UNIVERSITY   (Canada)

^d ST JOSEPH S HOSPITAL   (Canada)

^e ST MICHAEL'S HOSPITAL   (Canada)

^f SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^g UNIVERSITY OF TORONTO   (Canada)

Author keywords

Clinical trials; Critical care; Informed consent; Intensive care; Research; Research ethics; Surrogate decision makers

Indexed keywords

ADULT; ANXIETY DISORDER; ARTICLE; CRITICALLY ILL PATIENT; DECISION MAKING; DEPRESSION; FEMALE; HOSPITAL ANXIETY AND DEPRESSION SCALE; HUMAN; INFORMED CONSENT; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MEDICAL DECISION MAKING; MEDICAL RESEARCH; SURROGATE DECISION MAKING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ATTITUDE; CHILD; CHILD, PRESCHOOL; CRITICAL CARE; CRITICAL ILLNESS; DECISION MAKING; FEMALE; HUMANS; INFORMED CONSENT; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PATIENT PREFERENCE; YOUNG ADULT;

EID: 84866743844     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-012-2625-x     Document Type: Article

References (23)

1. Luce JM, Cook DJ, Martin TR, Angus DC, Boushey HA, Curtis JR, Heffner JE, Lanken PN, Levy MM, Polite PY, Rocker GM, Truog RD, American Thoracic Society (2004) The ethical conduct of clinical research involving critically ill patients in the United States and Canada: principles and recommendations. Am J Respir Crit Care Med 170:1375-1384
2. Fan E, Shahid S, Kondreddi VP, Bienvenu OJ, Mendez-Tellez PA, Pronovost PJ, Needham DM (2008) Informed consent in the critically ill: a two-step approach incorporating delirium screening. Crit Care Med 36(1):94-99
3. Scales DC, Smith OM, Pinto R, Barrett KA, Friedrich JO, Lazar NM, Cook DJ, Ferguson ND (2009) Patient's preferences for enrolment into criticalcare trials. Intensive Care Med 35:1703-1712
4. Lazar NM, Greiner GG, Robertson G, Singer PA (1996) Bioethics for clinicians. 5. Surrogate decisionmaking. CMAJ 155:1435-1437
5. Buchanan AE, Brock DW (1989) Deciding for others. Cambridge University Press, Cambridge
6. Beauchamp TL, Childress JF (2001) Principles of biomedical ethics. Oxford University Press, USA
7. Anonymous (2007) Directive 2001/20/EC of the European Parliament and of the Council of 4 April 2001 on the approximation of the laws, regulations and administrative provisions of the member states relating to the implementation of good clinical practice in the conduct of clinical trials on medicinal products for human use. Off J Eur Commun 1:33-44
8. Chenaud C, Merlani P, Verdon M, Ricou B (2009) Who should consent for research in adult intensive care? Preferences of patients and their relatives: a pilot study. J Med Ethics 35:709-712
9. Pochard F, Azoulay E, Chevret S, Lemaire F, Hubert P, Canoui P, Grassin M, Zittoun R, le Gall JR, Dhainaut JF, Schlemmer B; French FAMIREA Group (2001) Symptoms of anxiety and depression in family members of intensive care unit patients: ethical hypothesis regarding decision-making capacity. Crit Care Med 29:1893-1897
10. Myhren H, Ekeberg I, Langen I, Stokland O (2004) Emotional strain, communication, and satisfaction of family members in the intensive care unit compared with expectations of the medical staff: experiences from a Norwegian University Hospital. Intensive Care Med 30:1-8
11. Azoulay E, Pochard F, Kentish-Barnes N, Chevret S, Aboab J, Adrie C, Annane D, Bleichner G, Bollaert PE, Darmon M, Fassier T, Galliot R, Garrouste-Orgeas M, Goulenok C, Goldgran-Toledano D, Hayon J, Jourdain M, Kaidomar M, Laplace C, Larché J, Liotier J, Papazian L, Poisson C, Reignier J, Saidi F, Schlemmer B; FAMIREA Study Group (2005) Risk of post-traumatic stress symptoms in family members of intensive care unit patients. Am J Respir Crit Care Med 171:987-994
12. McAdam JL, Dracup KA, White DB, Fontaine DK, Puntillo KA (2010) Symptom experiences of family members of intensive care unit patients at high risk for dying. Crit Care Med 38:1078-1085
13. Pochard F, Darmon M, Fassier T, Bollaert PE, Cheval C, Coloigner M, Merouani A, Moulront S, Pigne E, Pingat J, Zahar JR, Schlemmer B, Azoulay E; French FAMIREA study group (2005) Symptoms of anxiety and depression in family members of intensive care unit patients before discharge or death. A prospective multicenter study. J Crit Care 20:90-96
14. McAdam JL, Puntillo K (2009) Symptoms experienced by family members of patients in intensive care units. Am J Crit Care 18:200-209 Quiz 210
15. Etchells E, Darzins P, Silberfeld M, Singer PA, McKenny J, Naglie G, Katz M, Guyatt GH, Molloy DW, Strang D (1999) Assessment of patient capacity to consent to treatment. J Gen Intern Med 14:27-34
16. Zigmond A, Snaith R (1987) The hospital anxiety and depression scale. Acta Psychiatr Scand 67:361-370
17. Perner A, Ibsen M, Bonde J (2010) Attitudes to drug trials among relatives of unconscious intensive care patients. BMC Anesthesiol 10:6
18. Luce JM (2009) Informed consent for clinical research involving patients with chest disease in the United States. Chest 135:1061-1068
19. Heyland DK, Cook DJ, Rocker GM, Dodek PM, Kutsogiannis DJ, Peters S, Tranmer JE, O'Callaghan CJ (2003) Decision-making in the ICU: perspectives of the surrogate decisionmaker. Intensive Care Med 29:75-82
20. *. Crit Care Med 32:1832-1838
21. Mehta S, Quittnat-Pelletier F, Brown M, Ethier C, Wells D, Burry L, MacDonald R (2012) Why surrogate decision makers provide or decline consent for ICU research studies: a questionnaire study. Intensive Care Med 38:47-54
22. Menon K, Ward RE, Gaboury I, Thomas M, Joffe A, Burns K, Cook D (2012) Factors affecting consent in pediatric critical care research. Intensive Care Med 38:153-159
23. Ciroldi M, Cariou A, Adrie C, Annane D, Castelain V, Cohen Y, Delahaye A, Joly LM, Galliot R, Garrouste-Orgeas M, Papazian L, Michel F, Barnes NK, Schlemmer B, Pochard F, Azoulay E; Famirea study group (2007) Ability of family members to predict patient's consent to critical care research. Intensive Care Med 33:807-81