Impact of triple-negative phenotype on prognosis of patients with breast cancer brain metastases

International Journal of Radiation Oncology Biology Physics

Volumn 84, Issue 3, 2012, Pages 612-618

  Xu, Zhiyuan ^a   Schlesinger, David ^b   Toulmin, Sushila ^a   Rich, Tyvin ^b   Sheehan, Jason ^a,c  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Brain metastases; Breast cancer; Stereotactic radiosurgery; Survival; Triple negative

Indexed keywords

BRAIN METASTASIS; BREAST CANCER; STEREOTACTIC RADIOSURGERY; SURVIVAL; TRIPLE-NEGATIVE;

BRAIN; DISEASES; FAULT TOLERANT COMPUTER SYSTEMS; MULTIVARIANT ANALYSIS; NATURAL LANGUAGE PROCESSING SYSTEMS; PATHOLOGY; RADIOTHERAPY; REGRESSION ANALYSIS;

FACTOR ANALYSIS;

ADULT; AGED; ARTICLE; BRAIN METASTASIS; CANCER CONTROL; CANCER PROGNOSIS; CANCER SURVIVAL; CONTROLLED STUDY; HUMAN; MAJOR CLINICAL STUDY; MULTIMODALITY CANCER THERAPY; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PHENOTYPE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; STEREOTACTIC RADIOSURGERY; SURVIVAL TIME; TRIPLE NEGATIVE BREAST CANCER;

ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; BONE NEOPLASMS; BRAIN NEOPLASMS; BREAST NEOPLASMS; CRANIAL IRRADIATION; FEMALE; HUMANS; LIVER NEOPLASMS; LUNG NEOPLASMS; MIDDLE AGED; PHENOTYPE; PROGNOSIS; RADIOSURGERY; RECEPTOR, ERBB-2; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TUMOR BURDEN;

EID: 84866742619     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.12.054     Document Type: Article

References (20)

1. R.J. Weil, D.C. Palmieri, and J.L. Bronder Breast cancer metastasis to the central nervous system Am J Pathol 167 2005 913 920
2. T. Sorlie, C.M. Perou, and R. Tibshirani Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications Proc Natl Acad Sci U S A 98 2001 10869 10874
3. F. Heitz, P. Harter, and H.J. Lueck Triple-negative and HER2-overexpressing breast cancers exhibit an elevated risk and an earlier occurrence of cerebral metastases Eur J Cancer 45 2009 2792 2798
4. H.S. Park, V.L. Chiang, and J.P. Knisely Stereotactic radiosurgery with or without whole-brain radiotherapy for brain metastases: an update Expert Rev Anticancer Ther 11 2011 1731 1738
5. P.W. Sperduto, S.T. Chao, and P.K. Sneed Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: A multi-institutional analysis of 4,259 patients Int J Radiat Oncol Biol Phys 77 2010 655 661
6. G. Jang, S.S. Lee, and J.H. Ahn Clinical features and course of brain metastases in triple-negative breast cancer: Comparison with human epidermal growth factor receptor 2-positive and other type at single institution in Korea Breast Cancer Res Treat 128 2011 171 177
7. S. Matsunaga, T. Shuto, and N. Kawahara Gamma Knife surgery for metastatic brain tumors from primary breast cancer: Treatment indication based on number of tumors and breast cancer phenotype J Neurosurg 113 Suppl. 2010 65 72
8. J.P. Sheehan, C.P. Yen, and J. Nguyen Timing and risk factors for new brain metastasis formation in patients initially treated only with Gamma Knife surgery. Clinical article J Neurosurg 114 2011 763 768
9. N. Kased, D.K. Binder, and M.W. McDermott Gamma Knife radiosurgery for brain metastases from primary breast cancer Int J Radiat Oncol Biol Phys 75 2009 1132 1140
10. D. Kondziolka, H. Kano, and G.L. Harrison Stereotactic radiosurgery as primary and salvage treatment for brain metastases from breast cancer. Clinical article J Neurosurg 114 2011 792 800
11. E.H. Romond, E.A. Perez, and J. Bryant Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer N Engl J Med 353 2005 1673 1684
12. A.M. Brufsky, M. Mayer, and H.S. Rugo Central nervous system metastases in patients with HER2-positive metastatic breast cancer: Incidence, treatment, and survival in patients from registHER Clin Cancer Res 17 2011 4834 4843
13. K. Yonemori, K. Tsuta, and M. Ono Disruption of the blood brain barrier by brain metastases of triple-negative and basal-type breast cancer but not HER2/neu-positive breast cancer Cancer 116 2010 302 308
14. P.D. Bos, X.H. Zhang, and C. Nadal Genes that mediate breast cancer metastasis to the brain Nature 459 2009 1005 1009
15. M. Smid, Y. Wang, and Y. Zhang Subtypes of breast cancer show preferential site of relapse Cancer Res 68 2008 3108 3114
16. R. Dent, W.M. Hanna, and M. Trudeau Pattern of metastatic spread in triple-negative breast cancer Breast Cancer Res Treat 115 2009 423 428
17. D. Palmieri, P.R. Lockman, and F.C. Thomas Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks Clin Cancer Res 15 2009 6148 6157
18. H. Aoyama, H. Shirato, and M. Tago Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: A randomized controlled trial JAMA 295 2006 2483 2491
19. P.K. Sneed, K.R. Lamborn, and J.M. Forstner Radiosurgery for brain metastases: Is whole brain radiotherapy necessary? Int J Radiat Oncol Biol Phys 43 1999 549 558
20. E.L. Chang, J.S. Wefel, and K.R. Hess Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: A randomised controlled trial Lancet Oncol 10 2009 1037 1044