-
4
-
-
33846433704
-
Beneficial effect of prolyl oligopeptidase inhibition on spatial memory in young but not in old scopolamine-treated rats
-
Jalkanen AJ, Puttonen KA, Venäläinen JI, Sinervä V, Mannila A, Ruotsalainen S, Jarho EM, Wallén EA, Männistö PT (2007) Beneficial effect of prolyl oligopeptidase inhibition on spatial memory in young but not in old scopolamine-treated rats. Basic Clin Pharmacol Toxicol 100:132-138
-
(2007)
Basic Clin Pharmacol Toxicol
, vol.100
, pp. 132-138
-
-
Jalkanen, A.J.1
Puttonen, K.A.2
Venäläinen, J.I.3
Sinervä, V.4
Mannila, A.5
Ruotsalainen, S.6
Jarho, E.M.7
Wallén, E.A.8
Männistö, P.T.9
-
5
-
-
80051808482
-
Inhibition of prolyl oligopeptidase by KYP-2047 fails to increase the extracellular neurotensin and substance P levels in rat striatum
-
Jalkanen AJ, Savolainen K, Forsberg MM (2011) Inhibition of prolyl oligopeptidase by KYP-2047 fails to increase the extracellular neurotensin and substance P levels in rat striatum. Neurosci Lett 502:107-111
-
(2011)
Neurosci Lett
, vol.502
, pp. 107-111
-
-
Jalkanen, A.J.1
Savolainen, K.2
Forsberg, M.M.3
-
6
-
-
0021016176
-
Degradation of neurotensin by rabbit brain endo-oligopeptidase A and endo-oligopeptidase B (proline-endopeptidase)
-
Camargo AC, Caldo H, Emson PC (1983) Degradation of neurotensin by rabbit brain endo-oligopeptidase A and endo-oligopeptidase B (proline-endopeptidase). Biochem Biophys Res Commun 116:1151-1159
-
(1983)
Biochem Biophys Res Commun
, vol.116
, pp. 1151-1159
-
-
Camargo, A.C.1
Caldo, H.2
Emson, P.C.3
-
7
-
-
0015821329
-
The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami
-
Carraway R, Leeman SE (1973) The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J Biol Chem 248:6854-6861
-
(1973)
J Biol Chem
, vol.248
, pp. 6854-6861
-
-
Carraway, R.1
Leeman, S.E.2
-
8
-
-
0027096345
-
Interaction between neurotensin and dopamine in the brain. Morphofunctional and clinical evidence
-
Rostene W, Brouard A, Dana C, Masuo Y, Agid F, Vial M, Lhiaubet AM, Pelaprat D (1992) Interaction between neurotensin and dopamine in the brain. Morphofunctional and clinical evidence. Ann NY Acad Sci 668:217-231
-
(1992)
Ann NY Acad Sci
, vol.668
, pp. 217-231
-
-
Rostene, W.1
Brouard, A.2
Dana, C.3
Masuo, Y.4
Agid, F.5
Vial, M.6
Lhiaubet, A.M.7
Pelaprat, D.8
-
10
-
-
0019863675
-
Neurotensin receptors are located on dopamine-containing neurones in rat midbrain
-
Palacios JM, Kuhar MJ (1981) Neurotensin receptors are located on dopamine-containing neurones in rat midbrain. Nature 294:587-589
-
(1981)
Nature
, vol.294
, pp. 587-589
-
-
Palacios, J.M.1
Kuhar, M.J.2
-
11
-
-
0032736399
-
Pharmacological, molecular and functional characterization of glial neurotensin receptors
-
Nouel D, Sarret P, Vincent JP, Mazella J, Beaudet A (1999) Pharmacological, molecular and functional characterization of glial neurotensin receptors. Neuroscience 94:1189-1197
-
(1999)
Neuroscience
, vol.94
, pp. 1189-1197
-
-
Nouel, D.1
Sarret, P.2
Vincent, J.P.3
Mazella, J.4
Beaudet, A.5
-
12
-
-
0034010170
-
Neurotensin regulates intracellular calcium in ventral tegmental area astrocytes: Evidence for the involvement of multiple receptors
-
Trudeau LE (2000) Neurotensin regulates intracellular calcium in ventral tegmental area astrocytes: evidence for the involvement of multiple receptors. Neuroscience 97:293-302
-
(2000)
Neuroscience
, vol.97
, pp. 293-302
-
-
Trudeau, L.E.1
-
13
-
-
1842458274
-
Specific involvement of neurotensin type 1 receptor in the neurotensin-mediated in vivo dopamine efflux using knock-out mice
-
Leonetti M, Brun P, Clerget M, Steinberg R, Soubrie P, Renaud B, Suaud-Chagny MF (2004) Specific involvement of neurotensin type 1 receptor in the neurotensin-mediated in vivo dopamine efflux using knock-out mice. J Neurochem 89:1-6
-
(2004)
J Neurochem
, vol.89
, pp. 1-6
-
-
Leonetti, M.1
Brun, P.2
Clerget, M.3
Steinberg, R.4
Soubrie, P.5
Renaud, B.6
Suaud-Chagny, M.F.7
-
14
-
-
30744438373
-
Virally mediated increased neurotensin 1 receptor in the nucleus accumbens decreases behavioral effects of mesolimbic system activation
-
Caceda R, Kinkead B, Owens MJ, Nemeroff CB (2005) Virally mediated increased neurotensin 1 receptor in the nucleus accumbens decreases behavioral effects of mesolimbic system activation. J Neurosci 25:11748-11756
-
(2005)
J Neurosci
, vol.25
, pp. 11748-11756
-
-
Caceda, R.1
Kinkead, B.2
Owens, M.J.3
Nemeroff, C.B.4
-
15
-
-
77952887117
-
Hyperactivity of the dopaminergic system in NTS1 and NTS2 null mice
-
Liang Y, Boules M, Li Z, Williams K, Miura T, Oliveros A, Richelson E (2010) Hyperactivity of the dopaminergic system in NTS1 and NTS2 null mice. Neuropharmacology 58:1199-1205
-
(2010)
Neuropharmacology
, vol.58
, pp. 1199-1205
-
-
Liang, Y.1
Boules, M.2
Li, Z.3
Williams, K.4
Miura, T.5
Oliveros, A.6
Richelson, E.7
-
16
-
-
79954529856
-
Clozapine and PD149163 elevate prepulse inhibition in Brown Norway rats
-
Feifel D, Shilling PD, Melendez G (2011) Clozapine and PD149163 elevate prepulse inhibition in Brown Norway rats. Behav Neurosci 125:268-272
-
(2011)
Behav Neurosci
, vol.125
, pp. 268-272
-
-
Feifel, D.1
Shilling, P.D.2
Melendez, G.3
-
17
-
-
1542267740
-
Role of calcium in neurotensin-evoked enhancement in firing in mesencephalic dopamine neurons
-
St-Gelais F, Legault M, Bourque MJ, Rompre PP, Trudeau LE (2004) Role of calcium in neurotensin-evoked enhancement in firing in mesencephalic dopamine neurons. J Neurosci 24: 2566-2574
-
(2004)
J Neurosci
, vol.24
, pp. 2566-2574
-
-
St-Gelais, F.1
Legault, M.2
Bourque, M.J.3
Rompre, P.P.4
Trudeau, L.E.5
-
18
-
-
33751375335
-
Bidirectional regulation of dopamine D2 and neurotensin NTS1 receptors in dopamine neurons
-
Jomphe C, Lemelin PL, OkanoH,Kobayashi K, Trudeau LE (2006) Bidirectional regulation of dopamine D2 and neurotensin NTS1 receptors in dopamine neurons. Eur J Neurosci 24:2789-2800
-
(2006)
Eur J Neurosci
, vol.24
, pp. 2789-2800
-
-
Jomphe, C.1
Lemelin, P.L.2
Okano, H.3
Kobayashi, K.4
Trudeau, L.E.5
-
19
-
-
70349574448
-
Presynaptic action of neurotensin on dopamine release through inhibition of D(2) receptor function
-
Fawaz CS, Martel P, Leo D, Trudeau LE (2009) Presynaptic action of neurotensin on dopamine release through inhibition of D(2) receptor function. BMC Neurosci 10:96
-
(2009)
BMC Neurosci
, vol.10
, pp. 96
-
-
Fawaz, C.S.1
Martel, P.2
Leo, D.3
Trudeau, L.E.4
-
20
-
-
0029784846
-
Cellular distribution of neurotensin receptors in rat brain: Immunohistochemical study using an antipeptide antibody against the cloned high affinity receptor
-
Boudin H, Pelaprat D, Rostene W, Beaudet A (1996) Cellular distribution of neurotensin receptors in rat brain: immunohistochemical study using an antipeptide antibody against the cloned high affinity receptor. J Comp Neurol 373:76-89
-
(1996)
J Comp Neurol
, vol.373
, pp. 76-89
-
-
Boudin, H.1
Pelaprat, D.2
Rostene, W.3
Beaudet, A.4
-
21
-
-
0034094032
-
Distribution of the neurotensin receptor NTS1 in the rat CNS studied using an amino-terminal directed antibody
-
Fassio A, Evans G, Grisshammer R, Bolam JP, Mimmack M, Emson PC (2000) Distribution of the neurotensin receptor NTS1 in the rat CNS studied using an amino-terminal directed antibody. Neuropharmacology 39:1430-1442
-
(2000)
Neuropharmacology
, vol.39
, pp. 1430-1442
-
-
Fassio, A.1
Evans, G.2
Grisshammer, R.3
Bolam, J.P.4
Mimmack, M.5
Emson, P.C.6
-
22
-
-
70249089694
-
Issues about the physiological functions of prolyl oligopeptidase based on its discordant spatial association with substrates and inconsistencies among mRNA, protein levels, and enzymatic activity
-
Myöhänen TT, García-Horsman JA, Tenorio-Laranga J, Männistö PT (2009) Issues about the physiological functions of prolyl oligopeptidase based on its discordant spatial association with substrates and inconsistencies among mRNA, protein levels, and enzymatic activity. J Histochem Cytochem 57:831-848
-
(2009)
J Histochem Cytochem
, vol.57
, pp. 831-848
-
-
Myöhänen, T.T.1
García-Horsman, J.A.2
Tenorio-Laranga, J.3
Männistö, P.T.4
-
23
-
-
34250875718
-
Distribution of immunoreactive prolyl oligopeptidase in human and rat brain
-
Myöhänen TT, Venäläinen JI, Tupala E, García-Horsman JA, Miettinen R, Männistö PT (2007) Distribution of immunoreactive prolyl oligopeptidase in human and rat brain. Neurochem Res 32:1365-1374
-
(2007)
Neurochem Res
, vol.32
, pp. 1365-1374
-
-
Myöhänen, T.T.1
Venäläinen, J.I.2
Tupala, E.3
García-Horsman, J.A.4
Miettinen, R.5
Männistö, P.T.6
-
24
-
-
79951694128
-
Association of prolyl oligopeptidase with conventional neurotransmitters in the brain
-
Peltonen I, Myöhänen TT, Männistö PT (2011) Association of prolyl oligopeptidase with conventional neurotransmitters in the brain. CNS Neurol Disord Drug Targets 10:311-318
-
(2011)
CNS Neurol Disord Drug Targets
, vol.10
, pp. 311-318
-
-
Peltonen, I.1
Myöhänen, T.T.2
Männistö, P.T.3
-
25
-
-
31044442639
-
Binding kinetics and duration of in vivo action of novel prolyl oligopeptidase inhibitors
-
Venäläinen JI, García-Horsman JA, Forsberg MM, Jalkanen A, Wallén EA, Jarho EM, Christiaans JA, Gynther J, Männistö PT (2006) Binding kinetics and duration of in vivo action of novel prolyl oligopeptidase inhibitors. Biochem Pharmacol 71:683-692
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 683-692
-
-
Venäläinen, J.I.1
García-Horsman, J.A.2
Forsberg, M.M.3
Jalkanen, A.4
Wallén, E.A.5
Jarho, E.M.6
Christiaans, J.A.7
Gynther, J.8
Männistö, P.T.9
-
26
-
-
81255160917
-
Brain Pharmacokinetics of two prolyl oligopeptidase inhibitors, JTP-4819 and KYP-2047, in the Rat
-
Jalkanen AJ, Hakkarainen JJ, Lehtonen M, Venäläinen T, Kääriäinen TM, Jarho E, Suhonen M, Forsberg MM (2011) Brain Pharmacokinetics of two prolyl oligopeptidase inhibitors, JTP-4819 and KYP-2047, in the Rat. Basic Clin Pharmacol Toxicol 109:443-451
-
(2011)
Basic Clin Pharmacol Toxicol
, vol.109
, pp. 443-451
-
-
Jalkanen, A.J.1
Hakkarainen, J.J.2
Lehtonen, M.3
Venäläinen, T.4
Kääriäinen, T.M.5
Jarho, E.6
Suhonen, M.7
Forsberg, M.M.8
-
27
-
-
7444243231
-
A cyclopent-2-enecarbonyl group mimics proline at the P2 position of prolyl oligopeptidase inhibitors
-
Jarho EM, Venäläinen JI, Huuskonen J, Christiaans JA, García- Horsman JA, Forsberg MM, Järvinen T, Gynther J, Männistö PT, Wallén EA (2004) A cyclopent-2-enecarbonyl group mimics proline at the P2 position of prolyl oligopeptidase inhibitors. J Med Chem 47:5605-5607
-
(2004)
J Med Chem
, vol.47
, pp. 5605-5607
-
-
Jarho, E.M.1
Venäläinen, J.I.2
Huuskonen, J.3
Christiaans, J.A.4
García-Horsman, J.A.5
Forsberg, M.M.6
Järvinen, T.7
Gynther, J.8
Männistö, P.T.9
Wallén, E.A.10
-
28
-
-
41549120972
-
Cellular and subcellular distribution of rat brain prolyl oligopeptidase and its association with specific neuronal neurotransmitters
-
Myöhänen TT, Venäläinen JI, García-Horsman JA, Piltonen M, Männistö PT (2008) Cellular and subcellular distribution of rat brain prolyl oligopeptidase and its association with specific neuronal neurotransmitters. J Comp Neurol 507:1694-1708
-
(2008)
J Comp Neurol
, vol.507
, pp. 1694-1708
-
-
Myöhänen, T.T.1
Venäläinen, J.I.2
García-Horsman, J.A.3
Piltonen, M.4
Männistö, P.T.5
-
29
-
-
43949142408
-
Spatial association of prolyl oligopeptidase, inositol 1,4,5-triphosphate type 1 receptor, substance P and its neurokinin-1 receptor in the rat brain: An immunohistochemical colocalization study
-
Myöhänen TT, Venäläinen JI, García-Horsman JA, Männistö PT (2008) Spatial association of prolyl oligopeptidase, inositol 1,4,5-triphosphate type 1 receptor, substance P and its neurokinin-1 receptor in the rat brain: an immunohistochemical colocalization study. Neuroscience 153:1177-1189
-
(2008)
Neuroscience
, vol.153
, pp. 1177-1189
-
-
Myöhänen, T.T.1
Venäläinen, J.I.2
García-Horsman, J.A.3
Männistö, P.T.4
-
30
-
-
0032830797
-
Quantitative studies of progesterone receptor and nitric oxide synthase colocalization with somatostatin, or neurotensin, or substance P in neurons of the guinea pig ventrolateral hypothalamic nucleus: An immunocytochemical triple-label analysis
-
Dufourny L, Warembourg M, JolivetA(1999) Quantitative studies of progesterone receptor and nitric oxide synthase colocalization with somatostatin, or neurotensin, or substance P in neurons of the guinea pig ventrolateral hypothalamic nucleus: an immunocytochemical triple-label analysis. J Chem Neuroanat 17:33-43
-
(1999)
J Chem Neuroanat
, vol.17
, pp. 33-43
-
-
Dufourny, L.1
Warembourg, M.2
Jolivet, A.3
-
31
-
-
0024352209
-
Production and characterization of a novel monoclonal antibody against neurotensin: Immunohistochemical localization in the midbrain and hypothalamus
-
Williams FG, Beitz AJ (1989) Production and characterization of a novel monoclonal antibody against neurotensin: immunohistochemical localization in the midbrain and hypothalamus. J Histochem Cytochem 37:831-841
-
(1989)
J Histochem Cytochem
, vol.37
, pp. 831-841
-
-
Williams, F.G.1
Beitz, A.J.2
-
33
-
-
33645397888
-
In heterozygous GDNF knockout mice the response of striatal dopaminergic system to acute morphine is altered
-
Airavaara M, Mijatovic J, Vihavainen T, Piepponen TP, Saarma M, Ahtee L (2006) In heterozygous GDNF knockout mice the response of striatal dopaminergic system to acute morphine is altered. Synapse 59:321-329
-
(2006)
Synapse
, vol.59
, pp. 321-329
-
-
Airavaara, M.1
Mijatovic, J.2
Vihavainen, T.3
Piepponen, T.P.4
Saarma, M.5
Ahtee, L.6
-
34
-
-
0023892141
-
Substance P-dopamine relationship in the rat substantia nigra: A light and electron microscopy study of double immunocytochemically labeled materials
-
Chang HT (1988) Substance P-dopamine relationship in the rat substantia nigra: a light and electron microscopy study of double immunocytochemically labeled materials. Brain Res 448:391-396
-
(1988)
Brain Res
, vol.448
, pp. 391-396
-
-
Chang, H.T.1
-
35
-
-
0023869424
-
Substance P in the rat nucleus accumbens: Ultrastructural localization in axon terminals and their relation to dopaminergic afferents
-
Pickel VM, Joh TH, Chan J (1988) Substance P in the rat nucleus accumbens: ultrastructural localization in axon terminals and their relation to dopaminergic afferents. Brain Res 444:247-264
-
(1988)
Brain Res
, vol.444
, pp. 247-264
-
-
Pickel, V.M.1
Joh, T.H.2
Chan, J.3
-
36
-
-
0025176536
-
Substance P afferents have synaptic contacts with dopaminergic neurons in the ventral tegmental area of the rat
-
Tamiya R, Hanada M, Kawai Y, Inagaki S, Takagi H (1990) Substance P afferents have synaptic contacts with dopaminergic neurons in the ventral tegmental area of the rat. Neurosci Lett 110:11-15
-
(1990)
Neurosci Lett
, vol.110
, pp. 11-15
-
-
Tamiya, R.1
Hanada, M.2
Kawai, Y.3
Inagaki, S.4
Takagi, H.5
-
37
-
-
0026696147
-
Substance P synaptic interactions with GABAergic and dopaminergic neurons in rat substantia nigra: An ultrastructural double-labeling immunocytochemical study
-
Mendez I, Elisevich K, Flumerfelt B (1992) Substance P synaptic interactions with GABAergic and dopaminergic neurons in rat substantia nigra: an ultrastructural double-labeling immunocytochemical study. Brain Res Bull 28:557-563
-
(1992)
Brain Res Bull
, vol.28
, pp. 557-563
-
-
Mendez, I.1
Elisevich, K.2
Flumerfelt, B.3
-
38
-
-
0025634571
-
Neurochemical consequences following injection of the substance P analogue, DiMe-C7, into the rat ventral tegmental area
-
Barnes JM, Barnes NM, Costall B, Cox AJ, Domeney AM, Kelly ME, Naylor RJ (1990) Neurochemical consequences following injection of the substance P analogue, DiMe-C7, into the rat ventral tegmental area. Pharmacol Biochem Behav 37:839-841
-
(1990)
Pharmacol Biochem Behav
, vol.37
, pp. 839-841
-
-
Barnes, J.M.1
Barnes, N.M.2
Costall, B.3
Cox, A.J.4
Domeney, A.M.5
Kelly, M.E.6
Naylor, R.J.7
-
39
-
-
0026633606
-
Effects of substance P on extracellular dopamine in neostriatum and nucleus accumbens
-
Boix F, Mattioli R, Adams F, Huston JP, Schwarting RK (1992) Effects of substance P on extracellular dopamine in neostriatum and nucleus accumbens. Eur J Pharmacol 216:103-107
-
(1992)
Eur J Pharmacol
, vol.216
, pp. 103-107
-
-
Boix, F.1
Mattioli, R.2
Adams, F.3
Huston, J.P.4
Schwarting, R.K.5
-
41
-
-
0029983547
-
Ability of angiotensin II to modulate striatal dopamine release via the AT1 receptor in vitro and in vivo
-
Brown DC, Steward LJ, Ge J, Barnes NM (1996) Ability of angiotensin II to modulate striatal dopamine release via the AT1 receptor in vitro and in vivo. Br J Pharmacol 118:414-420
-
(1996)
Br J Pharmacol
, vol.118
, pp. 414-420
-
-
Brown, D.C.1
Steward, L.J.2
Ge, J.3
Barnes, N.M.4
-
42
-
-
23844536770
-
Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion
-
Schulz I, Zeitschel U, Rudolph T, Ruiz-Carrillo D, Rahfeld JU, Gerhartz B, Bigl V, Demuth HU, Rossner S (2005) Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion. J Neurochem 94:970-979
-
(2005)
J Neurochem
, vol.94
, pp. 970-979
-
-
Schulz, I.1
Zeitschel, U.2
Rudolph, T.3
Ruiz-Carrillo, D.4
Rahfeld, J.U.5
Gerhartz, B.6
Bigl, V.7
Demuth, H.U.8
Rossner, S.9
-
43
-
-
84856348101
-
The effect of prolyl oligopeptidase inhibition on extracellular acetylcholine and dopamine levels in the rat striatum
-
Jalkanen AJ, Piepponen TP, Hakkarainen JJ, De Meester I, Lambeir AM, Forsberg MM (2012) The effect of prolyl oligopeptidase inhibition on extracellular acetylcholine and dopamine levels in the rat striatum. Neurochem Int 60:301-309
-
(2012)
Neurochem Int
, vol.60
, pp. 301-309
-
-
Jalkanen, A.J.1
Piepponen, T.P.2
Hakkarainen, J.J.3
De Meester, I.4
Lambeir, A.M.5
Forsberg, M.M.6
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