Predictive value of alpha-fetoprotein in the long-term risk of developing hepatocellular carcinoma in patients with hepatitis B virus infection - Results from a clinic-based longitudinal cohort

European Journal of Cancer

Volumn 48, Issue 15, 2012, Pages 2319-2327

  Hann, Hie Won ^a,b   Fu, Xiaoying ^b   Myers, Ronald E ^b   Hann, Richard S ^a   Wan, Shaogui ^b   Kim, Su Hee ^a   Au, Natalie ^a   Xing, Jinliang ^c   Yang, Hushan ^b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Alpha fetoprotein (AFP); Hepatitis B virus (HBV); Hepatocellular carcinoma (HCC)

Indexed keywords

ALPHA FETOPROTEIN;

ADULT; ARTICLE; CANCER RISK; COHORT ANALYSIS; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HEPATITIS B; HUMAN; LIVER CELL CARCINOMA; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RETROSPECTIVE STUDY; RISK FACTOR;

ADULT; ALPHA-FETOPROTEINS; CARCINOMA, HEPATOCELLULAR; COHORT STUDIES; FEMALE; HEPATITIS B; HUMANS; INCIDENCE; LIVER NEOPLASMS; LONGITUDINAL STUDIES; MALE; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84866728917     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2012.02.065     Document Type: Article

References (25)

1. D.M. Parkin, F. Bray, J. Ferlay, and P. Pisani Estimating the world cancer burden: Globocan 2000 Int J Cancer 94 2 2001 153 156
2. D.M. Parkin The global health burden of infection-associated cancers in the year 2002 Int J Cancer 118 12 2006 3030 3044
3. H.B. El-Serag, and K.L. Rudolph Hepatocellular carcinoma: epidemiology and molecular carcinogenesis Gastroenterology 132 7 2007 2557 2576
4. R.P. Beasley Hepatitis Bvirus. The major etiology of hepatocellular carcinoma Cancer 61 10 1988 1942 1956
5. H.E. Blum, and D. Moradpour Viral pathogenesis of hepatocellular carcinoma J Gastroenterol Hepatol 17 Suppl 3 2002 S413 S420
6. J.H. Kao, P.J. Chen, and D.S. Chen Recent advances in the research of hepatitis B virus-related hepatocellular carcinoma: epidemiologic and molecular biological aspects Adv Cancer Res 108 2010 21 72
7. P.A. Farazi, and R.A. DePinho Hepatocellular carcinoma pathogenesis: from genes to environment Nat Rev Cancer 6 9 2006 674 687
8. R.N. Aravalli, C.J. Steer, and E.N. Cressman Molecular mechanisms of hepatocellular carcinoma Hepatology 48 6 2008 2047 2063
9. C.G. Bergstrand, and B. Czar Demonstration of a new protein fraction in serum from the human fetus Scand J Clin Lab Invest 8 2 1956 174
10. M. Sherman Alphafetoprotein: an obituary J Hepatol 34 4 2001 603 605
11. J. Bruix, and M. Sherman Management of hepatocellular carcinoma Hepatology 42 5 2005 1208 1236
12. H. Oka, A. Tamori, T. Kuroki, K. Kobayashi, and S. Yamamoto Prospective study of alpha-fetoprotein in cirrhotic patients monitored for development of hepatocellular carcinoma Hepatology 19 1 1994 61 66
13. T.H. Chen, C.J. Chen, and M.F. Yen Ultrasound screening and risk factors for death from hepatocellular carcinoma in a high risk group in Taiwan Int J Cancer 98 2 2002 257 261
14. R.F. Velazquez, M. Rodriguez, and C.A. Navascues Prospective analysis of risk factors for hepatocellular carcinoma in patients with liver cirrhosis Hepatology 37 3 2003 520 527
15. M. Colombo, R. de Franchis, and E. Del Ninno Hepatocellular carcinoma in Italian patients with cirrhosis N Engl J Med 325 10 1991 675 680
16. S.R. Digumarthy, D.V. Sahani, and S. Saini MRI in detection of hepatocellular carcinoma (HCC) Cancer Imaging 5 1 2005 20 24
17. C.J. Chen, H.I. Yang, and J. Su Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level JAMA 295 1 2006 65 73
18. R.C. Frazee, J.W. Roberts, and R.E. Symmonds A prospective randomized trial comparing open versus laparoscopic appendectomy Ann Surg 219 6 1994 725 728 [discussion 728-31]
19. C.J. Chen, H.I. Yang, and U.H. Iloeje Hepatitis B virus DNA levels and outcomes in chronic hepatitis B Hepatology 49 5 Suppl 2009 S72 S84
20. H.L. Chan, A.Y. Hui, and M.L. Wong Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma Gut 53 10 2004 1494 1498
21. M.F. Yuen, Y. Tanaka, and D.Y. Fong Independent risk factors and predictive score for the development of hepatocellular carcinoma in chronic hepatitis B J Hepatol 50 1 2009 80 88
22. P. Sizaret, A. Tuyns, and N. Martel Alpha-fetoprotein levels in normal males from seven ethnic groups with different hepatocellular carcinoma risks Ann NY Acad Sci 259 1975 136 155
23. J.E. O'Brien, E. Dvorin, and A. Drugan Race-ethnicity-specific variation in multiple-marker biochemical screening: alpha-fetoprotein, hCG, and estriol Obstet Gynecol 89 3 1997 355 358
24. A.S. Lok, R.K. Sterling, and J.E. Everhart Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma Gastroenterology 138 2 2010 493 502
25. F. Trevisani, P.E. D'Intino, and A.M. Morselli-Labate Serum alpha-fetoprotein for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: influence of HBsAg and anti-HCV status J Hepatol 34 4 2001 570 575