Chromogranin a-derived peptides are involved in innate immunity

Current Medicinal Chemistry

Volumn 19, Issue 24, 2012, Pages 4115-4123

  Aslam, R ^a   Atindehou, M ^a   Lavaux, T ^a   Haikel Y ^a   Schneider, F ^a   Metz Boutigue, M H ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Antibiotics; Antimicrobial peptides; Bacterial proteases; Catestatin; Chromofungin; Chromogranins; Immune system; Innate immunity; Neuroendocrine system; Neutrophils; Salmonella enteritis; Staphylococcus aureus; Synergy

Indexed keywords

CATESLYTIN; CATESTATIN; CHROMOFUNGIN; CHROMOGRANIN A; CHROMOGRANIN B; GLU C PROTEASE; MINOCYCLINE; POLYPEPTIDE ANTIBIOTIC AGENT; PROCATESTATIN; PROTEINASE; SECRETOGRANIN II; UNCLASSIFIED DRUG; VASOSTATIN I; VORICONAZOLE;

ANTIMICROBIAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; DRUG POTENTIATION; HOST PATHOGEN INTERACTION; INNATE IMMUNITY; NEUTROPHIL; NONHUMAN; PROTEIN DEGRADATION; SALMONELLA ENTERITIDIS; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CATTLE; CHROMOGRANIN A; FUNGI; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; MOLECULAR SEQUENCE DATA; NEUTROPHILS; PEPTIDE FRAGMENTS; SALMONELLA; SERINE ENDOPEPTIDASES; STAPHYLOCOCCUS AUREUS;

EID: 84866716800     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712802430063     Document Type: Article

References (48)

1. Bulet, P.; Stocklin, R.; Menin, L. Anti-microbial peptides: from invertebrates to vertebrates. Immunol. Rev., 2004, 198, 169-184.
2. Aerts, A.M.; François, I.E.; Cammue, B.P.; Thevissen, K. The mode of antifungal action of plant, insect and human defensins. Cell. Mol. Life Sci., 2008, 65(12), 2069-2079.
3. Manners, J.M. Hidden weapons of microbial destruction in plant genomes. Genome Biol., 2007, 8(9), 225.
4. Yeaman, M.R.; Yount, N.Y. Mechanisms of antimicrobial peptide action and resistance. Pharmacol. Rev., 2003, 55(1), 27-55.
5. Yang, D.; Biragyn, A.; Kwak, L.W.; Oppenheim, J.J. Mammalian defensins in immunity: more than just microbicidal. Trends Immunol., 2002, 23(6), 291-296.
6. Zanetti, M. Cathelicidins, multifunctional peptides of the innate immunity. J. Leukocyte Biol., 2004, 75(1), 39-48.
7. Helle, K.B. The granin family of uniquely acidic proteins of the diffuse neuroendocrine system: comparative and functional aspects. Biol. Rev. Cambr. Philo. Soc., 2004, 79(4), 769-794.
8. Metz-Boutigue, M.H.; Garcia-Sablone, P.; Hogue-Angeletti, R.; Aunis, D. Intracellular and extracellular processing of chromogranin A. Determination of cleavage sites. Eur. J. Biochem., 1993, 217(1), 247-257.
9. Strub, J.M.; Garcia-Sablone, P.; Lonning, K.; Taupenot, L.; Hubert, P.; Van Dorsselaer, A.; Aunis, D.; Metz-Boutigue, M.H. Processing of chromogranin B in bovine adrenal medulla. Identification of secretolytin, the endogenous C-terminal fragment of residues 614-626 with antibacterial activity. Eur. J. Biochem., 1995, 229(2), 356-368.
10. Seidah, N.G.; Chretien, M. Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides. Brain Res., 1999, 848(1-2), 45-62.
11. Anouar, Y.; Yon, L.; Desmoucelles, C.; Leprince, J.; Breault, L.; Gallo-Payet, N.; Vaudry, H. Identification of a novel secretogranin II-derived peptide in the adult and fetal human adrenal gland. Endocr. Res. 1998, 24(3-4), 731-736.
12. Marksteiner, J.; Kirchmair, R.; Mahata, S.K.; Mahata, M.; Fischer-Colbrie, R.; Hogue-Angeletti, R.; Saria, A.; Winkler, H. Distribution of secretoneurin, a peptide derived from secretogranin II, in rat brain: an immunocytochemical and radioimmunological study. Eur. J. Neurosci., 1993, 54(4), 923-944.
13. Yajima, A.; Ikeda, M.; Miyazaki, K.; Maeshima, T.; Narita, N.; Narita, M.; Manserin, a novel peptide from secretogranin II in the neuroendocrine system. Neuroreport, 2004, 15(11), 1755-1759.
14. Eiden, L.E. Is chromogranin a prohormone? Nature, 1987, 325(6102), 301.
15. Tatemoto, K.; Efendi, S.; Mutt, V.; Makk, G.; Feistner, G.J; Barchas, J.D. Pancreastatin, a novel pancreatic peptide that inhibits insulin secretion. Nature, 1986, 324(6096), 476-478.
16. Helle, K.B.; Corti, A.; Metz-Boutigue, M.H.; Tota, B. The endocrine role for chromogranin A: a prohormone for peptides with regulatory properties. Cell. Mol. Life Sci., 2007, 64(22), 2863-2886.
17. Strub, J.M.; Hubert, P.; Nullans, G.; Aunis, D.; Metz-Boutigue, M.H. Antibacterial activity of secretolytin, a chromogranin B-derived peptide (614-626), is correlated with peptide structure. FEBS Lett., 1996, 379(3), 273-278.
18. Metz-Boutigue, M.H.; Goumon, Y.; Lugardon, K.; Strub, J.M.; Aunis, D. Antibacterial peptides are present in chromaffin cell secretory granules. Cell. Mol. Neurobiol., 1998, 18(2), 249-266.
19. Lugardon, K.; Raffner, R.; Goumon, Y.; Corti, A.; Delmas, A.; Bulet, P.; Aunis, D.; Metz-Boutigue, M.H. Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A. J. Biol. Chem., 2000, 275(15), 10745-10753.
20. Briolat, J.; Wu, S.D.; Mahata, S.K.; Gonthier, B.; Bagnard, D.; Chasserot-Golaz, S.; Helle, K.B.; Aunis, D.; Metz-Boutigue, M.H. New antimicrobial activity for the catecholamine release-inhibitory peptide from chromogranin A. Cell. Mol. Life Sci., 2005, 62(3), 377-385.
21. Radek, K.A.; Lopez-Garcia, B.; Hupe, M.; Niesman, I.R.; Elias, P.M.; Taupenot, L; Mahata, S.K.; O'Connor, D.T; Gallo, R.L. The neuroendocrine peptide catestatin is a cutaneous antimicrobial and induced in the skin after injury. J. Invest. Dermatol., 2008, 128(6), 1525-1534.
22. Sternberg, E.M. Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens. Nat. Rev. Immunol., 2006, 6(4), 318-328.
23. Strub, J.M.; Goumon, Y.; Lugardon, K.; Capon, C.; Lopez, M.; Moniatte, M.; Van Dorsselaer, A.; Aunis, D.; Metz-Boutigue, M.H. Antibacterial activity of glycosylated and phosphorylated chromogranin A-derived peptide 173-194 from bovine adrenal medullary chromaffin granules. J. Biol. Chem., 1996, 271(45), 28533-28540.
24. Maget-Dana, R.; Metz-Boutigue, M.H.; Helle, K.B. The N-terminal domain of chromogranin A (CgA1-40) interacts with monolayers of membrane lipids of fungal and mammalian compositions. Ann. N. Y. Acad. Sci., 2002, 971, 352-354.
25. Shooshtarizadeh, P.; Zhang, D.; Chich, J.F.; Gasnier, C.; Schneider, F.; Haïkel, Y.; Aunis, D.; Metz-Boutigue, M.H. The antimicrobial peptides derived from chromogranin/secretogranin family, new actors of innate immunity. Regul. Peptides, 2010, 165(1), 102-110.
26. Lugardon, K.; Chasserot-Golaz, S.; Kieffer, A.E.; Maget-Dana, R.; Nullans, G.; Kieffer, B.; Aunis, D.; Metz-Boutigue, M.H. Structural and biological characterization of chromofungin, the antifungal chromogranin A-(47-66)-derived peptide. J. Biol. Chem., 2001, 276(38), 35875-35882.
27. Yoo, S.H. Identification of the Ca(2+)-dependent calmodulin-binding region of chromogranin A. Biochemistry, 1992, 31(26), 6134-6140.
28. Blois, A.; Holmsen, H.; Martino, G.; Corti, A.; Metz-Boutigue, M.H.; Helle, K.B. Interactions of chromogranin A-derived vasostatins and monolayers of phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine. Regul. Peptides, 2006, 134(1), 30-37.
29. Taylor, C.V.; Taupenot, L.; Mahata, S.K.; Mahata, M.; Wu, H.; Yasothornsrikul, S.; Toneff, T.; Caporale, C.; Jiang, Q.; Parmer, R.J.; Hook, V.Y.; O'Connor, D.T. Formation of the catecholamine release-inhibitory peptide catestatin from chromogranin A. Determination of proteolytic cleavage sites in hormone storage granules. J. Biol. Chem., 2000, 275(30), 22905-22915.
30. Biswas, N.; Rodriguez-Flores, J.L.; Courel, M.; Gayen, J.; Vaingankar, S.M.; Mahata, M.; Torpey, J.W.; Taupenot, L.; O'Connor, D.T.; Mahata, S.K. Cathepsin L colocalizes with chromogranin A in chromaffin vesicles to generate active peptides. Endocrinology, 2009, 150(8), 3547-3557.
31. Mahata, S.K.; O'Connor, D.T.; Mahata, M.; Yoo, S.H.; Taupenot, L.; Wu, H;, Gill, B.M.; Parmer, R.J. Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist. J. Clin. Invest., 1997, 100(6), 1623-1633.
32. Valore, E.V.; Ganz, T. Posttranslational processing of defensins in immature human myeloid cells. Blood, 1992, 79, 1538-1544.
33. Brogden, K.A. Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria? Nat Rev. Microbiol., 2005, 3, 238-250.
34. Jenssen, H.; Hamill, P.; Hancock, R.E. Peptide antimicrobial agents. Clin. Microbiol. Rev. 2006, 19, 491-511.
35. Zhang, D.; Shooshtarizadeh, P.; Laventie, B.J.; Colin, D.A. ; Chich, J.F. ;Vidic, J. ; de Barry, J.; Chasserot-Golaz, S. ; Delalande, F. ; Van Dorsselaer, A. ; Schneider, F.; Helle, K.; Aunis, D.; Prévost, G. ; Metz-Boutigue, M.H. Two Chromogranin A-derived peptides induce calcium entry in human neutrophils by calmodulin regulated calcium independent phospholipase A2. PLoS One., 2009, 4(2), e4501.
36. Herrero, C.J.; Ales, E.; Pintado, A.J.; Lopez, M.G.; Garcia-Palomero, E.; Mahata, S.K.; O'Connor, D.T.; Garcia, A.G.; Montiel, C. Modulatory mechanism of the endogenous peptide catestatin on neuronal nicotinic acetylcholine receptors and exocytosis. J. Neurosci. 2002, 22, 377-388.
37. Angelone, T.; Quintieri, A.M.; Brar, B.K.; Limchaiyawat, P.T.; Tota, B.; Mahata, S.K.; Cerra, M.C. The antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropism. Endocrinology, 2008, 149, 4780-4793.
38. Gorkiewicz, G. Nosocomial and antibiotic-associated diarrhea caused by organisms other than Clostridium difficile. Int. J. Antimicrob. Ag., 2009, 33(Suppl 1), S37-41.
39. Garnier, J.; Gibrat, J.F.; Robson, B.; GOR secondary structure prediction method version IV. Methods in Enzymology, 1996, 266, 540-553, Doolittle R. F. Ed.
40. Fairlie, D.P.; Tyndall, J.D. ; Reid, R.C. ; Wong, A.K. ; Abbenante, G. ; Scanlon, M.J.; March, D.R. ; Bergman, D.A. ; Chai, C.L. ; Burkett, B.A. Confirmational selection of inhibitors and substrates by proteolytic enzymes: implications for drug design and polypeptide processing. J. Med. Chem., 2000, 43(7):1271-1281.
41. Biran, V.; Gaudin, A.; Mariani-Kurdjian, P.; Doit, C.; Bingen, E.; Aujard, Y. Implication of extended-spectrum beta-lactamase enterobacteriaceae in nosocomial infections in neonates. Arch. Pediatrie, 2010, 17(Suppl 4), S150-153.
42. Tsakris, A.; Poulou, A.; Markou, F.; Pitiriga, V.; Piperaki, E.T.; Kristo, I.; Pournaras, S. Dissemination of clinical isolates of Klebsiella oxytoca harboring CMY-31, VIM-1, and a New OXY-2-type variant in the community. Antimicrob. Agents Chemother., 2011, 55(7), 3164-3168.
43. Hoffmann, K.M.; Deutschmann, A.; Weitzer, C.; Joainig, M.; Zechner, E.; Hogenauer, C.; Hauer, A.C. Antibiotic-associated hemorrhagic colitis caused by cytotoxin-producing Klebsiella oxytoca. Pediatrics, 2010, 125(4), e960-963.
44. Plessier, A.; Cosnes, J.; Gendre, J.P.; Beaugerie, L. Intercurrent Klebsiella oxytoca colitis in a patient with Crohn's disease. Gastroenterol. Clin. Biol., 2002, 26(8-9), 799-800.
45. Medalla, F.; Sjölund-Karlsson, M.; Shin, S.; Harvey, E.; Joyce, K.; Theobald, L.; Nygren, B.N.; Pecic, G.; Gay, K.; Austin, J.; Stuart, A.; Blanton, E.; Mintz, E. D.; Whichard, J. M.; Barzilay, E. J. Ciprofloxacinresistant Salmonella enterica Serotype Typhi, United States, 1999-2008. Emerging Infectious Diseases, 2011, 17(6), 1095-1098.
46. Su, L.H.; Teng, W.S.; Chen, C.L.; Lee, H.Y.; Li, H.C.; Wu, T.L.; Chiu, C.H. Increasing ceftriaxone resistance in Salmonellae, Taiwan. Emerg. Infect. Dis., 2011, 17(6), 1086-1090.
47. Serra, P.; Brandimarte, C.; Martino, P.; Carlone, S.; Giunchi, G. Synergistic treatment of enterococcal endocarditis: in vitro and in vivo studies. Arch. Intern. Med., 1977, 137(11), 1562-1567.
48. Desbois AP, Tschörner D, Coote PJ. Survey of small antifungal peptides with chemotherapeutic potential. Curr. Pharm. Biotechnol. 2011, 12(8):1263-1291.