Ferula asafoetida : Traditional uses and pharmacological activity

Pharmacognosy Reviews

Volumn 6, Issue 12, 2012, Pages 141-146

  Mahendra, Poonam ^a   Bisht, Shradha ^a  

^a SURESH GYAN VIHAR UNIVERSITY   (India)

Author keywords

Ferula asafoetida; spice; umbelliferae

Indexed keywords

ALOE VERA EXTRACT; ANTHELMINTIC AGENT; ANTINEOPLASTIC AGENT; ARABINOSE; ATROPINE; AZULENE; BETA PINENE; CHLORPHENIRAMINE; DIALLYL DISULFIDE; ESSENTIAL OIL; FERULA ASSAFOETIDA EXTRACT; FERULIC ACID; GALACTOSE; GLUCOSE; GLUCURONIC ACID; HERBACEOUS AGENT; INDOMETACIN; ISOPIMPINELLIN; LUTEOLIN; NIGELLA SATIVA EXTRACT; PINENE; PLANT EXTRACT; PROPRANOLOL; RHAMNOSE; TERPINEOL; UMBELLIFERONE; UNCLASSIFIED DRUG; VALERIC ACID; VANILLIN; WARFARIN;

AMENORRHEA; ANALGESIC ACTIVITY; ANTHELMINTIC ACTIVITY; ANTIBACTERIAL ACTIVITY; ANTICONVULSANT ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ANTIVIRAL ACTIVITY; ASAFOETIDA; ASTHMA; AYURVEDA; BLOOD PRESSURE; BRONCHITIS; CENTRAL NERVOUS SYSTEM; COLIC; CYTOTOXICITY; DERMATITIS; DIURETIC ACTIVITY; FLATULENCE; GALLSTONE; GENE EXPRESSION; HEART; HUMAN; HYSTERIA; INDIA; INFANTILE PNEUMONIA; LIVER PROTECTION; LYMPHOMA; METHEMOGLOBINEMIA; NEPHROLITHIASIS; NONHUMAN; PERTUSSIS; REVIEW; SEDATION; STREPTOZOCIN DIABETES; TRADITIONAL MEDICINE; ULCER; VASODILATATION;

APIACEAE; FERULA ASSA-FOETIDA;

EID: 84866696934     PISSN: 09737847     EISSN: 09762787     Source Type: Journal    
DOI: 10.4103/0973-7847.99948     Document Type: Review

References (64)

1. Eigner D, Scholz D. Ferula assa-foetida and Curcuma longa in traditional medical treatment and diet in Nepal. J Ethnopharmacol 1999;67:1-6.
2. Mahran, GH, El Alfy TS, Ansari SM. A phytochemical study of volatile oil of Afghanian asafetida. Bull Fac Pharm Cairo Univ 1973;12:101-7.
3. Duke JA, Ayensu ES. Medicinal plants of China. Vol. 1. Algonac, Michigan: Reference Publications Inc.; 1985. P. 52-361.
4. Buddrus J, Bauer H, Abu-Mustafa E, Khattab A, Mishaal S, El-Khrisy EA, et al. Foetidin, a sesquiterpenoid coumarin from Ferula assa-foetida. Phytochemistry 1985;24:869-70.
5. Gimlette JD. A dictionary of Malayan medicine. New York, USA: Oxford University Press; 1939.
6. Bellakhdar J, Claisse R, Fleuretin J, Younos C. Repertory of standard herbal drugs in the Moroccan Pharmacopoeia. J Ethnopharmacol 1991;35:123-43.
7. Bhattarai NK. Folk Anthelmintic drugs of central Nepal. Int J Pharmacol 1992;30:145-50.
8. Seabrook WB. Adventures in Arabia among the Bedouins, Druses, whirling dervishes and Yezidee devil worshipers. New York: Blue Ribbon Book; 1927. p. 99-105.
9. Elisabetsky E, Figueiredo W, Oliveria G. Traditional Amazonian nerve tonics as antidepressant agents: Chaunochiton kappleri: A case study. J Herbs Spices Med Plants 1992;1:125-62.
10. Seetharam KA, Pasricha JS. Condiments and contact dermatitis of the fi nger-tips. Indian J Dermatol Venerol Leprol 1987;53:325-8.
11. Anon. Lilly's handbook of pharmacy and therapeutics. 5th rev. Indianapolis: Eli Lilly and Co.; 1898.
12. Tiwar KC, Majumder R, Bhattacharjee S. Folklore medicines from Assam and Arunachal Pradesh (district Tirap). Int J Crude Drug Res 1979;17:61-7.
13. Kamboj VP. A review of Indian medicinal plants with interceptive activity. Indian J Med Res 1988;1988:336-55.
14. Subrahmanyan V, Sastry VL, Srinivasan M. Asafoetida. J Sci Ind Res B 1954;13:382-6.
15. Venkataraghavan S, Sundareesan TP. A short note on contraceptive in Ayurveda. J Sci Res Pl Med 1981;2:39.
16. Joshi P. Herbal drugs used in Guinea worm disease by the tribals of southern Rajasthan (India). Int J Pharmacog 1991;29:33-8.
17. John D. One hundred useful raw drugs of the Kani tribes of Trivandrum forest division, Kerala, India. Int J Crude Drug Res 1984;22:17-39.
18. Mahran GH, El-Alfy TS, Ansary HA. A phytochemical study of the gum and resin of Afghanian asafoetida. Bull Fac Pharm 1975;12:119-32.
19. Fujita M, Furuya T, Itokawa H. Crude drugs containing coumarins and their derivatives. III. Chromatographic separation and determination of umbelliferone and its homologs. Yakugaku Zasshi 1958;78:395-8.
20. Nassar MI. Spectral study of farnesiferol B from Ferula assafoetida L. Pharmazie 1994;49:542-3.
21. Caglioti L, Naef H, Arigoni D, Jeger O. Sesquiterpenes and azulenes. CXXVII. The constituents of asafetida. II. Farnesiferol B and C. Helv Chim Acta 1959;42:2557-70.
22. Shankaranarayana ML, Raghavan B, Natarajan CP. Odorous compounds of asafetida. VII. Isolation and identifi cation. Indian Food Pack 1982;36:65-76.
23. Rajanikanth B, Ravindranath B, Shankaranarayana ML. Volatile polysulphides of asafoetida. Phytochemistry 1984;23:899-900.
24. Agrawal AK, Rao CV, Sairam K, Joshi VK, Goel RK. Effect of Piper longum Linn, Zingiber offi cinalis Linn and Ferula species on gastric ulceration and secretion in rats. Indian J Exp Biol 2000;38:994-8.
25. Fatehi M, Farifteh F, Fatehi-Hassanabad Z. Antispasmodic and hypotensive effects of Ferula asafoetida gum extract. J Ethnopharmacol 2004;91:321-4.
26. Platel K, Srinivasan K. Infl uence of dietary spices on their active principles on digestive enzymes of small intestinal mucosa in rats. Int J Food Sci Nutr 1996;47:55-9.
27. Desai HG, Kalro RH. Effect of black pepper and asafetida on the DNA content of gastric aspirates. Indian J Med Res 1985;81:325-9.
28. Platel K, Srinivasan K. Infl uence of dietary spices and their active principles on pancreatic digestive enzymes in albino rats. Nahrung 2000;44:42-6.
29. Pradeep KU, Geervani P, Eggum BO. Infl uence of spices on utilization of sorghum and chickpea protein. Plant Foods Hum Nutr 199;41:269-76.
30. Unnikrishn MC, Kuttan R. Cytotoxicity of extracts of spices to cultured cells. Nutr Cancer 1988;11:251-7.
31. Sato A. Studies on anti-tumor activity of crude drugs. I. The effects of aqueous extracts of some crude drugs in short-term screening test. Yakugaku Zasshi 1989;109:407-23.
32. Unnikrishn MC, Kuttan R. Tumour reducing and anticarcinogenic activity of selected spices. Cancer Lett 1990;51:85-9.
33. Mallikarjuna GU, Dhanalakshmi S, Raisuddin S, Rao AR. Chemomodulatory infl uence of Ferula asafoetida on mammary epithelial differentiation, hepatic drug metabolizing enzymes, antioxidant profi les and N-methyl-N-nitrosourea- induced mammary carcinogenesis in rats. Breast Cancer Res Treat 2003;81:1-10.
34. Unnikrishnan MC, Kuttan R. Tumour reducing and anticarcinogenic activity of selected spices. Cancer Lett 1990;51:85-9.
35. Lu Y, Xu C, Yang Y, Pan H. The effect of antioxidant sodium ferulate on human lymphocytes apoptosis induced by H2O2. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 1998;20:44-8.
36. Aruna K, Sivaramakrishnan VM. Anticarcinogenic effect of some Indian plant products. Food Chem Toxicol 1992;30:953-6.
37. Keshr G, Lakshmi V, Singh MM, Kamboj VP. Post-coital antifertility actiivty of Ferula asafoetida extract in female rats. Pharmac Biol 1999;37:273-8.
38. Das PC. Oral contraceptive (longacting). Patent Brit 1,445,599 1976; 11.
39. Das PC. Oral contraceptive. Patent-Brit-1,025,372 1966.
40. Misra MB, Mishra SS, Misra RK. Screening of a few indigenous abortifacients. J Indian Med Assoc 1969;52:535.
41. Shashikanth KN, Hosono A. In vitro mutagenicity of tropical spices to streptomycin dependent strains of Salmonella typhimurium TA98. Agric Biol Chem 1986;50:2947-8.
42. Siwaswamy SN, Balachandran B, Balanehru S, Sivaramakrishnan VM. Mutagenic activity of south Indian food items. Indian J Exp Biol 1991;29:730-7.
43. Abraham SK, Kesavan PC. Genotoxicity of garlic, turmeric and asafetida in mice. Mutat Res 1984;136:85-8.
44. Soni KB, Lahiri M, Chakcradeo P, Bhide SV, Kuttan R. Protective effect of food additives on afl atoxininduced mutagenicity and hepatocarcinogenicity. Chem Lett 1997;115:129-33.
45. Soudamini KK, Unnikrishnan MC, Sukumaran K, Kuttan R. Mutagenicity and anti-mutagenicity of selected spices. Indian J Physiol Pharmacol 1995;39:347-53.
46. Boyd LJ. The pharmacology of the homeopathic drugs. I. J Am Inst Homeopathy 1928;21:7.
47. Sarkisyan RG. Effect of Ferula on arterial pressure. Meditsinskii Zhurnal Uzbekistana1969;1969:23-4.
48. Mansurov MM. Effect of Ferula asafoetida on the blood coagulability. Meditsinskii Zhurnal Uz bekistana 1967;1967(6):46-9.
49. Bordia A, Arora SK. The effect of essential oil (active principle) of asafetida on alimentary lipemia. Indian J Med Res 1975;63:707-11.
50. Garg DK, Banerjea AC, Verma J. The role of intestinal Clostridia and the effect of asafetida (Hing) and alcohol in fl atulence. Indian J Microbiol 1980;20:194-7.
51. Dikshi A, Husain A. Antifungal action of some essential oils against animal pathogens. Fitoterapia 1984;55:171-6.
52. Soni KB, Rajan A, Kuttan R. Reversal of afl atoxin induced liver damage by turmeric and curcumin. Cancer Lett 1992;66:115-21.
53. Thyagaraja N, Hosono A. Effect of spice extract on fungal inhibition. Food Sci Technol (London) 1996;29:286-8.
54. Ramadan, NI, Al Khadrawy FM. The in vitro effect of Assafoetida on Trichomonas vaginalis. J Egypt Soc Parasitol 2003;33:615-30.
55. Rahlfs VW, Mossinger P. Asafoetida in the treatment of the irritable colon. A double blind study. Dtsch Med Wochenschr 1979;104:140-3.
56. Kamanna VS, Chandrasekhara N. Effect of garlic (Allium sativum Linn) on serum lipoproteins and lipoprotein cholesterol levels in albino rats rendered hypercholesteremic by feeding cholesterol. Lipids 1982;17:483-8.
57. Al-Awadi F, Shoukry M. The lipid lowering effect of an antidiabetic plant extract. Acta Diabetol 1988;25:1-5.
58. Soni KB, Rajan A, Kuttan R. Inhibition of afl atoxin-induced liver damage in ducklings by food additives. Mycotoxin Res 1993;9:22-7.
59. Sambaiah K, Srinivasan K. Infl uence of spices and spice principles on hepatic mixed function oxygenase system in rats. Indian J Biochem Biophys 1989;26:254-8.
60. Coleman DE. The effect of certainhomeopathic remedies upon the hearing. J Am Inst Homeopathy 1922;15:279-81.
61. Al-Awadi FM, Khattar MA, Gumaa KA. On the mechanism of the hypoglycaemic effect of a plant extract. Diabetologia 1985;28:432-4.
62. Kelly KJ, Neu J, Camitta BM, Honig GR. Methemoglobinemia in an infant treated with the folk remedy glycerited asafoetida. Pediatrics 1984;73:717-9.
63. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7.
64. Walia K. Effect of asafoetida (7-hydroxycoumarin) on mouse spermatocytes. Cytologia 1973;38:719-24.