Influence of hormonal control on LH pulsatility and secretion in women with classical congenital adrenal hyperplasia

European Journal of Endocrinology

Volumn 167, Issue 4, 2012, Pages 499-505

  Bachelot, Anne ^a   Chakhtoura, Zeina ^a   Plu Bureau, Geneviève ^b   Coudert, Mathieu ^a   Coussieu, Christiane ^a   Badachi, Yasmina ^a   Dulon, Jérome ^a   Charbit, Beny ^a   Touraine, Philippe ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b université Paris Cité   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; DYDROGESTERONE; ESTRADIOL; FLUDROCORTISONE; FOLLITROPIN; HYDROCORTISONE; HYDROXYPROGESTERONE; LUTEINIZING HORMONE; PROGESTERONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

ADULT; AMENORRHEA; ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; CLUSTER ANALYSIS; CONGENITAL ADRENAL HYPERPLASIA; CONTROLLED STUDY; FEMALE; HUMAN; HYPOGONADOTROPIC HYPOGONADISM; LUTEINIZING HORMONE RELEASE; MENSTRUAL IRREGULARITY; OLIGOMENORRHEA; PATIENT COMPLIANCE; PRIORITY JOURNAL; SALT WASTING; VIRILIZATION;

ADOLESCENT; ADRENAL HYPERPLASIA, CONGENITAL; ADULT; ANDROGENS; ANDROSTENEDIONE; CASE-CONTROL STUDIES; FEMALE; HORMONE REPLACEMENT THERAPY; HORMONES; HUMANS; LUTEINIZING HORMONE; PROGESTERONE; TESTOSTERONE; YOUNG ADULT;

EID: 84866658707     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-12-0454     Document Type: Article

References (29)

1. White PC & Speiser PW. Congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Endocrine Reviews 2000 21 245-291. (doi:10.1210/er.21.3.245)
2. Ogilvie CM, Crouch NS, Rumsby G, Creighton SM, Liao LM & Conway GS. Congenital adrenal hyperplasia in adults: a review of medical, surgical and psychological issues. Clinical Endocrinology 2006 64 2-11. (doi:10.1111/j.1365- 2265.2005.02410.x)
3. Helleday J, Siwers B, Ritzen EM & Carlstrom K. Subnormal androgen and elevated progesterone levels in women treated for congenital virilizing 21-hydroxylase deficiency. Journal of Clinical Endocrinology and Metabolism 1993 76 933-936. (doi:10.1210/jc.76.4.933)
4. Holmes-Walker DJ, Conway GS, Honour JW, Rumsby G & Jacobs HS. Menstrual disturbance and hypersecretion of progesterone in women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Clinical Endocrinology 1995 43 291-296. (doi:10.1111/j.1365-2265.1995.tb02034.x)
5. Levin JH, Carmina E & Lobo RA. Is the inappropriate gonadotropin secretion of patients with polycystic ovary syndrome similar to that of patients with adult-onset congenital adrenal hyperplasia? Fertility and Sterility 1991 56 635-640.
6. Rebar R, Judd HL, Yen SS, Rakoff J, Vandenberg G & Naftolin F. Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome. Journal of Clinical Investigation 1976 57 1320-1329. (doi:10.1172/JCI108400)
7. Taylor AE, McCourt B, Martin KA, Anderson EJ, Adams JM, Schoenfeld D & Hall JE. Determinants of abnormal gonadotropin secretion in clinically defined women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 1997 82 2248-2256. (doi:10.1210/jc.82.7.2248)
8. Pastor CL, Griffin-Korf ML, Aloi JA, Evans WS & Marshall JC. Polycystic ovary syndrome: evidence for reduced sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone. Journal of Clinical Endocrinology and Metabolism 1998 83 582-590. (doi:10.1210/jc.83.2.582)
9. Chhabra S, McCartney CR, Yoo RY, Eagleson CA, Chang RJ & Marshall JC. Progesterone inhibition of the hypothalamic gonadotropin-releasing hormone pulse generator: evidence for varied effects in hyperandrogenemic adolescent girls. Journal of Clinical Endocrinology and Metabolism 2005 90 2810-2815. (doi:10.1210/jc.2004-2359)
10. Eagleson CA, Gingrich MB, Pastor CL, Arora TK, Burt CM, Evans WS & Marshall JC. Polycystic ovarian syndrome: evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone. Journal of Clinical Endocrinology and Metabolism 2000 85 4047-4052. (doi:10.1210/jc.85.11.4047)
11. Barnes RB, Rosenfield RL, Ehrmann DA, Cara JF, Cuttler L, Levitsky LL & Rosenthal IM. Ovarian hyperandrogynism as a result of congenital adrenal virilizing disorders: evidence for perinatal masculinization of neuroendocrine function in women. Journal of Clinical Endocrinology and Metabolism 1994 79 1328-1333. (doi:10.1210/jc.79.5.1328)
12. Belgorosky A, Chahin S & Rivarola MA. Elevation of serum luteinizing hormone levels during hydrocortisone treatment in infant girls with 21-hydroxylase deficiency. Acta Paediatrica 1996 85 1172-1175. (doi:10.1111/j.1651-2227.1996.tb18223.x)
13. Bachelot A, Plu-Bureau G, Thibaud E, Laborde K, Pinto G, Samara D, Nihoul-Fékété C, Kuttenn F, Polak M & Touraine P. Long-term outcome of patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Hormone Research 2007 67 268-276. (doi:10.1159/000098017)
14. Hatch R, Rosenfield RL, Kim MH & Tredway D. Hirsutism: implications, etiology, and management. American Journal of Obstetrics and Gynecology 1981 140 815-830.
15. Veldhuis JD & Johnson ML. Cluster analysis: a simple, versatile, and robust algorithm for endocrine pulse detection. American Journal of Physiology 1986 250 E486-E493.
16. Evans WS, Sollenberger MJ, Booth RA Jr, Rogol AD, Urban RJ, Carlsen EC, Johnson ML & Veldhuis JD. Contemporary aspects of discrete peak-detection algorithms. II. The paradigm of the luteinizing hormone pulse signal in women. Endocrine Reviews 1992 13 81-104. (doi:10.1210/edrv-13-1-81)
17. Ward J. Hierarchical grouping to optimize an objective function. Journal of the American Statistical Association 1963 58 236-244. (doi:10.1080/01621459. 1963.10500845)
18. Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Human Reproduction 2004 19 41-47. (doi:10.1093/humrep/deh098)
19. Couzinet B, Young J, Brailly S, Chanson P, Thomas JL & Schaison G. The antigonadotropic activity of progestins (19-nortestosterone and 19-norprogesterone derivatives) is not mediated through the androgen receptor. Journal of Clinical Endocrinology and Metabolism 1996 81 4218-4223. (doi:10.1210/jc.81.12.4218)
20. Soules MR, Steiner RA, Clifton DK, Cohen NL, Aksel S & Bremner WJ. Progesterone modulation of pulsatile luteinizing hormone secretion in normal women. Journal of Clinical Endocrinology and Metabolism 1984 58 378-383. (doi:10.1210/jcem-58-2-378)
21. Couzinet B, Young J, Kujas M, Meduri G, Brailly S, Thomas JL, Chanson P & Schaison G. The antigonadotropic activity of a 19-nor-progesterone derivative is exerted both at the hypothalamic and pituitary levels in women. Journal of Clinical Endocrinology and Metabolism 1999 84 4191-4196. (doi:10.1210/jc.84.11.4191)
22. Bry-Gauillard H, Meduri G, Abirached F, Constancis E, Brailly S, Chanson P & Young J. Primary amenorrhea revealing an occult progesterone-secreting ovarian tumor. Fertility and Sterility 2008 90 1198.e1-1198.e5. (doi:10.1016/j.fertnstert.2007.11.064)
23. Dewis P, Newman M, Ratcliffe WA & Anderson DC. Does testosterone affect the normal menstrual cycle? Clinical Endocrinology 1986 24 515-521. (doi:10.1111/j.1365-2265.1986.tb03280.x)
24. Dunaif A. Do androgens directly regulate gonadotropin secretion in the polycystic ovary syndrome? Journal of Clinical Endocrinology and Metabolism 1986 63 215-221. (doi:10.1210/jcem-63-1-215)
25. Serafini P, Silva PD, Paulson RJ, Elkind-Hirsch K, Hernandez M & Lobo RA. Acute modulation of the hypothalamic-pituitary axis by intravenous testosterone in normal women. American Journal of Obstetrics and Gynecology 1986 155 1288-1292.
26. Mulaikal RM, Migeon CJ & Rock JA. Fertility rates in female patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. New England Journal of Medicine 1987 316 178-182. (doi:10.1056/NEJM198701223160402)
27. Jaaskelainen J, Hippelainen M, Kiekara O & Voutilainen R. Child rate, pregnancy outcome and ovarian function in females with classical 21-hydroxylase deficiency. Acta Obstetricia et Gynecologica Scandinavica 2000 79 687-692. (doi:10.1034/j.1600-0412.2000.079008687.x)
28. Hoepffner W, Schulze E, Bennek J, Keller E & Willgerodt H. Pregnancies in patients with congenital adrenal hyperplasia with complete or almost complete impairment of 21-hydroxylase activity. Fertility and Sterility 2004 81 1314-1321. (doi:10.1016/j.fertnstert.2003.10.024)
29. Casteràs A, De Silva P, Rumsby G & Conway GS. Reassessing fecundity in women with classical congenital adrenal hyperplasia (CAH): normal pregnancy rate but reduced fertility rate. Clinical Endocrinology 2009 70 833-837. (doi:10.1111/j.1365-2265.2009.03563.x)