메뉴 건너뛰기




Volumn 24, Issue 5, 2012, Pages 257-267

Treatment of community-acquired pneumonia with moxifloxacin: A meta-analysis of randomized controlled trials

Author keywords

Community acquired pneumonia; Meta analysis; Moxifloxacin

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AZITHROMYCIN; BETA LACTAM ANTIBIOTIC; CEFOPERAZONE; CEFTRIAXONE; CEFUROXIME; CLARITHROMYCIN; ERYTHROMYCIN; LEVOFLOXACIN; MACROLIDE; MOXIFLOXACIN; ROXITHROMYCIN;

EID: 84866641556     PISSN: 1120009X     EISSN: 19739478     Source Type: Journal    
DOI: 10.1179/1973947812Y.0000000028     Document Type: Article
Times cited : (14)

References (38)
  • 1
    • 0030814012 scopus 로고    scopus 로고
    • In vitro activity of BAY 12-8039, a novel 8-methoxyquinolone, compared to activities of six fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis
    • Brueggemann AB, Kugler KC, Doern GV. In vitro activity of BAY 12-8039, a novel 8-methoxyquinolone, compared to activities of six fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Antimicrob Agents Chemother. 1997;41:1594-7.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1594-1597
    • Brueggemann, A.B.1    Kugler, K.C.2    Doern, G.V.3
  • 2
    • 0033802361 scopus 로고    scopus 로고
    • Benchmarking the in vitro activities of moxifloxacin and comparator agents against recent respiratory isolates from 377 medical centers throughout the United States
    • Jones ME, Staples AM, Critchley I, Thornsberry C, Heinze P, Enjler HD, et al. Benchmarking the in vitro activities of moxifloxacin and comparator agents against recent respiratory isolates from 377 medical centers throughout the United States. Antimicrob Agents Chemother. 2000;44:2645-52.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 2645-2652
    • Jones, M.E.1    Staples, A.M.2    Critchley, I.3    Thornsberry, C.4    Heinze, P.5    Enjler, H.D.6
  • 4
    • 0032558314 scopus 로고    scopus 로고
    • Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?
    • Moher D, Pham B, Jones A, Cook DJ, Jadad AR, Moher M, et al. Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? Lancet. 1998;352:609-13.
    • (1998) Lancet , vol.352 , pp. 609-613
    • Moher, D.1    Pham, B.2    Jones, A.3    Cook, D.J.4    Jadad, A.R.5    Moher, M.6
  • 5
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629-34.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3    Minder, C.4
  • 6
    • 17744397528 scopus 로고    scopus 로고
    • CAP5 Moxifloxacin Study Group. Oral moxifloxacin vs. high-dosage amoxicillin in the treatment of mild-to-moderate, community-acquired, suspected pneumococcal pneumonia in adults
    • Petitpretz P, Arvis P, Marel M, Moita J, Urueta J. CAP5 Moxifloxacin Study Group. Oral moxifloxacin vs. high-dosage amoxicillin in the treatment of mild-to-moderate, community-acquired, suspected pneumococcal pneumonia in adults. Chest. 2001;119:185-95.
    • (2001) Chest , vol.119 , pp. 185-195
    • Petitpretz, P.1    Arvis, P.2    Marel, M.3    Moita, J.4    Urueta, J.5
  • 7
    • 0036096232 scopus 로고    scopus 로고
    • Randomized Controlled Trial of Sequential Intravenous (i.v.) and Oral Moxifloxacin Compared with Sequential i.v. and Oral Co-Amoxiclav with or without Clarithromycin in Patients with Community-Acquired Pneumonia Requiring Initial Parenteral Treatment
    • Finch R, Schurmann D, Collins O, Kubin R, McGivern J, Bobbaers H, et al. Randomized Controlled Trial of Sequential Intravenous (i.v.) and Oral Moxifloxacin Compared with Sequential i.v. and Oral Co-Amoxiclav with or without Clarithromycin in Patients with Community-Acquired Pneumonia Requiring Initial Parenteral Treatment. Antimicrob Agents Chemother. 2002;46:1746-54.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 1746-1754
    • Finch, R.1    Schurmann, D.2    Collins, O.3    Kubin, R.4    McGivern, J.5    Bobbaers, H.6
  • 8
    • 0041692462 scopus 로고    scopus 로고
    • A comparison of moxifloxacin and amoxicillin in the treatment of community-acquired pneumonia in Latin America: Results of a multicenter clinical trial
    • Jardim JR, Rico G, de la Roza C, Obispo E, Urueta J, Wolff M, et al. A comparison of moxifloxacin and amoxicillin in the treatment of community-acquired pneumonia in Latin America: Results of a multicenter clinical trial. Archivos de Bronconeumologia. 2003;39(9):387-93.
    • (2003) Archivos De Bronconeumologia , vol.39 , Issue.9 , pp. 387-393
    • Jardim, J.R.1    Rico, G.2    de la Roza, C.3    Obispo, E.4    Urueta, J.5    Wolff, M.6
  • 9
    • 0037249385 scopus 로고    scopus 로고
    • Effectiveness of oral moxifloxacin in standard first-line therapy in community-acquired pneumonia
    • Torres A, Muir JF, Corris P, Kubin R, Duprat-Lomon I, Sagnier PP, et al. Effectiveness of oral moxifloxacin in standard first-line therapy in community-acquired pneumonia. Eur Respir J. 2003;21:135-43.
    • (2003) Eur Respir J , vol.21 , pp. 135-143
    • Torres, A.1    Muir, J.F.2    Corris, P.3    Kubin, R.4    Duprat-Lomon, I.5    Sagnier, P.P.6
  • 10
    • 6344243659 scopus 로고    scopus 로고
    • Safety and efficacy of sequential i.v. to p.o. moxifloxacin versus conventional combination therapies for the treatment of community-acquired pneumonia in patients requiring initial i.v. therapy
    • Katz E, Larsen LS, Fogarty CM, Hamed K, Song J, Choudhri S. Safety and efficacy of sequential i.v. to p.o. moxifloxacin versus conventional combination therapies for the treatment of community-acquired pneumonia in patients requiring initial i.v. therapy. J Emerg Med. 2004;27:395-405.
    • (2004) J Emerg Med , vol.27 , pp. 395-405
    • Katz, E.1    Larsen, L.S.2    Fogarty, C.M.3    Hamed, K.4    Song, J.5    Choudhri, S.6
  • 11
    • 28744456644 scopus 로고    scopus 로고
    • Study Group Moxirapid. Treatment with Sequential Intravenous or Oral Moxifloxacin Was Associated with Faster Clinical Improvement than Was Standard Therapy for Hospitalized Patients with Community-Acquired Pneumonia Who Received Initial Parenteral Therapy
    • Welte T, Petermann W, Schurmann D, Bauer TT, Reimnitz P, Study Group Moxirapid. Treatment with Sequential Intravenous or Oral Moxifloxacin Was Associated with Faster Clinical Improvement than Was Standard Therapy for Hospitalized Patients with Community-Acquired Pneumonia Who Received Initial Parenteral Therapy. Clin Infect Dis. 2005;41:1697-705.
    • (2005) Clin Infect Dis , vol.41 , pp. 1697-1705
    • Welte, T.1    Petermann, W.2    Schurmann, D.3    Bauer, T.T.4    Reimnitz, P.5
  • 12
    • 21644455261 scopus 로고    scopus 로고
    • Moxifloxacin monotherapy compared to amoxicillin-clavu-lanate plus roxithromycin for nonsevere community-acquired pneumonia in adults with risk factors
    • Portier H, Brambilla C, Garre M, Paganin F, Poubeau P, Zuck P. Moxifloxacin monotherapy compared to amoxicillin-clavu-lanate plus roxithromycin for nonsevere community-acquired pneumonia in adults with risk factors. Eur J Clin Microbiol Infect Dis. 2005;24:367-76.
    • (2005) Eur J Clin Microbiol Infect Dis , vol.24 , pp. 367-376
    • Portier, H.1    Brambilla, C.2    Garre, M.3    Paganin, F.4    Poubeau, P.5    Zuck, P.6
  • 13
    • 44649106400 scopus 로고    scopus 로고
    • Efficacy and safety of intravenous moxifloxacin versus cefoperazone with azithromycin in the treatment of community acquired pneu-monia
    • Xu S, Xiong S, Xu Y, Liu J, Liu H, Zhao J, et al. Efficacy and safety of intravenous moxifloxacin versus cefoperazone with azithromycin in the treatment of community acquired pneu-monia. J Huazhong Univ Sci Technolog Med Sci. 2006;26:421-4.
    • (2006) J Huazhong Univ Sci Technolog Med Sci , vol.26 , pp. 421-424
    • Xu, S.1    Xiong, S.2    Xu, Y.3    Liu, J.4    Liu, H.5    Zhao, J.6
  • 14
    • 43249099098 scopus 로고    scopus 로고
    • Moxifloxacin monotherapy is effective in hospitalized patients with community-acquired pneumonia: The MOTIV study a randomized clinical trial
    • Torres A, Garau J, Arvis P, Carlet J, Choudhri S, Kureishi A, et al. Moxifloxacin monotherapy is effective in hospitalized patients with community-acquired pneumonia: the MOTIV study a randomized clinical trial. Clin Infect Dis. 2008;46:1499-509.
    • (2008) Clin Infect Dis , vol.46 , pp. 1499-1509
    • Torres, A.1    Garau, J.2    Arvis, P.3    Carlet, J.4    Choudhri, S.5    Kureishi, A.6
  • 15
    • 0035180495 scopus 로고    scopus 로고
    • Safety and efficacy of sequential (IV to PO) moxifloxacin for the treatment of community-acquired pneu-monia in hospitalized patients
    • File TM Jr, Larsen LS, Fogarty CM, Schechter RB, Peloquin S, Choudhri S., et al. Safety and efficacy of sequential (IV to PO) moxifloxacin for the treatment of community-acquired pneu-monia in hospitalized patients. Today's Therapeutic Trends. 2001;19:251-70.
    • (2001) Today's Therapeutic Trends , vol.19 , pp. 251-270
    • File Jr., T.M.1    Larsen, L.S.2    Fogarty, C.M.3    Schechter, R.B.4    Peloquin, S.5    Choudhri, S.6
  • 16
    • 30344445070 scopus 로고    scopus 로고
    • Phase III double-blind comparative study of BAY 12-8039 (moxifloxacin) versus levofloxacin in patients with community-acquired pneumonia
    • Hiroyuki K, Nobuki A, Yoshihito N, Akira W, Shin K, Shigeki O, et al. Phase III double-blind comparative study of BAY 12-8039 (moxifloxacin) versus levofloxacin in patients with community-acquired pneumonia. Jpn J Chemother. 2005;53(s-3):27-46.
    • (2005) Jpn J Chemother , vol.53 , Issue.s-3 , pp. 27-46
    • Hiroyuki, K.1    Nobuki, A.2    Yoshihito, N.3    Akira, W.4    Shin, K.5    Shigeki, O.6
  • 17
    • 29244479536 scopus 로고    scopus 로고
    • Community-acquired pneumonia recovery in the elderly (CAPRIE): Efficacy and safety of moxifloxacin therapy versus that of levofloxacin therapy
    • Anzueto A, Niederman MS, Pearle J, Restrepo MI, Heyder A, Choudhri S., et al. Community-acquired pneumonia recovery in the elderly (CAPRIE): Efficacy and safety of moxifloxacin therapy versus that of levofloxacin therapy. Clin Infect Dis. 2006;42:73-81.
    • (2006) Clin Infect Dis , vol.42 , pp. 73-81
    • Anzueto, A.1    Niederman, M.S.2    Pearle, J.3    Restrepo, M.I.4    Heyder, A.5    Choudhri, S.6
  • 18
    • 38449101354 scopus 로고    scopus 로고
    • A brief review of moxifloxacin in the treatment of elderly patients with community-acquired pneumonia (CAP)
    • Ferrara AM. A brief review of moxifloxacin in the treatment of elderly patients with community-acquired pneumonia (CAP). Clin Intery Aging. 2007;2:179-87.
    • (2007) Clin Intery Aging , vol.2 , pp. 179-187
    • Ferrara, A.M.1
  • 19
    • 34548559282 scopus 로고    scopus 로고
    • National Hospital Ambulatory Medical Care Survey: 2005 emergency department summary
    • Nawar EW, Niska RW, Xu J. National Hospital Ambulatory Medical Care Survey: 2005 emergency department summary. Adv Data. 2007;386:1-32.
    • (2007) Adv Data , vol.386 , pp. 1-32
    • Nawar, E.W.1    Niska, R.W.2    Xu, J.3
  • 20
    • 84878030972 scopus 로고    scopus 로고
    • Healthcare Cost and Utilization Project Nationwide Inpatient Sample, [cited 2008 Aug 12]. Available from
    • Healthcare Cost and Utilization Project Nationwide Inpatient Sample 2006. [cited 2008 Aug 12]. Available from: http://hcupnet.ahrq.gov.
    • (2006)
  • 22
    • 0036366750 scopus 로고    scopus 로고
    • Associations between empirical antimicrobial therapy at the hospital and mortality in patients with severe community-acquired pneumonia
    • Rello J, Catalan M, Diaz E, Bodi M, Alvarez B. Associations between empirical antimicrobial therapy at the hospital and mortality in patients with severe community-acquired pneumonia. Intensive Care Med. 2002;28:1030-5.
    • (2002) Intensive Care Med , vol.28 , pp. 1030-1035
    • Rello, J.1    Catalan, M.2    Diaz, E.3    Bodi, M.4    Alvarez, B.5
  • 23
    • 0034727809 scopus 로고    scopus 로고
    • Increasing prevalence of multidrug-resistant Streptococcus pneumoniae in the United States
    • Whitney CG, Farley MM, Hadler J, Harrison LH, Lexau C, Reingold A, et al. Increasing prevalence of multidrug-resistant Streptococcus pneumoniae in the United States. N Engl J Med. 2000;343:1917-24.
    • (2000) N Engl J Med , vol.343 , pp. 1917-1924
    • Whitney, C.G.1    Farley, M.M.2    Hadler, J.3    Harrison, L.H.4    Lexau, C.5    Reingold, A.6
  • 24
    • 0036499123 scopus 로고    scopus 로고
    • Regional trends in antimicrobial resistance among clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States: Results from the TRUST Surveillance Program, 1999-2000
    • Thornsberry C, Sahm DF, Kelly LJ, Critchley IA, Jones ME, Evangelista AT et al. Regional trends in antimicrobial resistance among clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States: results from the TRUST Surveillance Program, 1999-2000. Clin Infect Dis. 2002;34(Suppl. 1):S4-16.
    • (2002) Clin Infect Dis , vol.34 , Issue.SUPPL. 1
    • Thornsberry, C.1    Sahm, D.F.2    Kelly, L.J.3    Critchley, I.A.4    Jones, M.E.5    Evangelista, A.T.6
  • 25
    • 0345668474 scopus 로고    scopus 로고
    • Geographic diversity and temporal trends of antimicrobial resistance in Streptococcus pneumoniae in the United States
    • McCormick AW, Whitney CG, Farley MM, Lynfield R, Harrison LE, Bennett NM, et al. Geographic diversity and temporal trends of antimicrobial resistance in Streptococcus pneumoniae in the United States. Nat Med. 2003;9:424-30.
    • (2003) Nat Med , vol.9 , pp. 424-430
    • McCormick, A.W.1    Whitney, C.G.2    Farley, M.M.3    Lynfield, R.4    Harrison, L.E.5    Bennett, N.M.6
  • 26
    • 33847155159 scopus 로고    scopus 로고
    • Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults
    • Mandell LA, Wunderink RG, Anzueto A, Bartlett JG, Campbell GD, Dean NC et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis. 2007;44(Suppl 2):527-72.
    • (2007) Clin Infect Dis , vol.44 , Issue.SUPPL. 2 , pp. 527-572
    • Mandell, L.A.1    Wunderink, R.G.2    Anzueto, A.3    Bartlett, J.G.4    Campbell, G.D.5    Dean, N.C.6
  • 27
    • 37049010143 scopus 로고    scopus 로고
    • The safety profile of moxifloxacin and other fluoroquinolones in special patient populations
    • Iannini PB. The safety profile of moxifloxacin and other fluoroquinolones in special patient populations. Curr Med Res Opin. 2007;23(9):2303.
    • (2303) Curr Med Res Opin , vol.23 , Issue.9 , pp. 2007
    • Iannini, P.B.1
  • 28
    • 0032723032 scopus 로고    scopus 로고
    • Efficacy and safety of moxifloxacin vs. clarithromycin for community-acquired pneumonia
    • Fogarty C, Grossman C, Williams J, Haverstock D, Church D. Efficacy and safety of moxifloxacin vs. clarithromycin for community-acquired pneumonia. Infect Med. 1999;16(11):748-63
    • (1999) Infect Med , vol.16 , Issue.11 , pp. 748-763
    • Fogarty, C.1    Grossman, C.2    Williams, J.3    Haverstock, D.4    Church, D.5
  • 29
    • 0034933394 scopus 로고    scopus 로고
    • CAP1 Study Group. The efficacy and safety of two oral moxifloxacin regimens (200 mg or 400 mg once-daily x 10 days) compared to oral clarithromycin (500 mg twice-daily x 10 days) in the treatment of community-acquired pneumonia
    • Hoeffken G, Meyer HP, Winter J, Verhoef L, CAP1 Study Group. The efficacy and safety of two oral moxifloxacin regimens (200 mg or 400 mg once-daily x 10 days) compared to oral clarithromycin (500 mg twice-daily x 10 days) in the treatment of community-acquired pneumonia. Respir Med. 2001;95:553-64.
    • (2001) Respir Med , vol.95 , pp. 553-564
    • Hoeffken, G.1    Meyer, H.P.2    Winter, J.3    Verhoef, L.4
  • 30
  • 31
    • 8744257509 scopus 로고    scopus 로고
    • Efficacy and safety of sequential moxifloxacin for treatment of community-acquired pneumonia associated with atypical pathogens
    • Hoeffken G, Talan D, Larsen LS, Peloquin S, Choudhri S., Haverstock D, et al. Efficacy and safety of sequential moxifloxacin for treatment of community-acquired pneumonia associated with atypical pathogens. Eur J Clin Microbiol Infect Dis. 2004;23:772-5.
    • (2004) Eur J Clin Microbiol Infect Dis , vol.23 , pp. 772-775
    • Hoeffken, G.1    Talan, D.2    Larsen, L.S.3    Peloquin, S.4    Choudhri, S.5    Haverstock, D.6
  • 32
    • 77953020737 scopus 로고    scopus 로고
    • Moxifloxacin monotherapy versus beta-lactam-based standard therapy for community-acquired pneumonia: A meta-analysis of randomised controlled trials
    • An MM, Zou Z, Shen H, Gao PH, Cao YB, Jiang YY. Moxifloxacin monotherapy versus beta-lactam-based standard therapy for community-acquired pneumonia: a meta-analysis of randomised controlled trials. Int J Antimicrob Agents. 2010;36:58-65.
    • (2010) Int J Antimicrob Agents , vol.36 , pp. 58-65
    • An, M.M.1    Zou, Z.2    Shen, H.3    Gao, P.H.4    Cao, Y.B.5    Jiang, Y.Y.6
  • 33
    • 57349155272 scopus 로고    scopus 로고
    • Respiratory fluoroquinolones for the treatment of community-acquired pneumonia: A meta-analysis of randomized controlled trials
    • Vardarkas KZ, Siempos II, Grammatikos A, Athanassa Z, Korbila IP, Falagas ME. Respiratory fluoroquinolones for the treatment of community-acquired pneumonia: a meta-analysis of randomized controlled trials. CMAJ. 2008;179(12):1269-77.
    • (2008) CMAJ , vol.179 , Issue.12 , pp. 1269-1277
    • Vardarkas, K.Z.1    Siempos, I.I.2    Grammatikos, A.3    Athanassa, Z.4    Korbila, I.P.5    Falagas, M.E.6
  • 34
    • 65949098180 scopus 로고    scopus 로고
    • Safety profile of the respiratory fluoroquinolone moxifloxacin: Comparison with other fluor-oquinolones and other antibacterial classes
    • Van Bambeke F, Tulkens PM. Safety profile of the respiratory fluoroquinolone moxifloxacin: comparison with other fluor-oquinolones and other antibacterial classes. Drug Safety. 2009;32:359-78.
    • (2009) Drug Safety , vol.32 , pp. 359-378
    • van Bambeke, F.1    Tulkens, P.M.2
  • 35
    • 28144464151 scopus 로고    scopus 로고
    • CAPRIE Study Group. A Randomized Trial Comparing the Cardiac Rhythm Safety of Moxifloxacin vs. Levofloxacin in Elderly Patients Hospitalized With Community-Acquired Pneumonia
    • Morganroth J, DiMarco JP, Anzueto A, Niederman MS, Choudhri S, CAPRIE Study Group. A Randomized Trial Comparing the Cardiac Rhythm Safety of Moxifloxacin vs. Levofloxacin in Elderly Patients Hospitalized With Community-Acquired Pneumonia. Chest. 2005;128:3398-406.
    • (2005) Chest , vol.128 , pp. 3398-3406
    • Morganroth, J.1    Dimarco, J.P.2    Anzueto, A.3    Niederman, M.S.4    Choudhri, S.5
  • 36
    • 0032750074 scopus 로고    scopus 로고
    • Basic pharmaocokinetics of moxifloxacin
    • Stass H, Kubitza D. Basic pharmaocokinetics of moxifloxacin. Drugs. 1999;58(Suppl 2):225-6.
    • (1999) Drugs , vol.58 , Issue.SUPPL. 2 , pp. 225-226
    • Stass, H.1    Kubitza, D.2
  • 37
    • 0032729634 scopus 로고    scopus 로고
    • Metabolism and excretion of moxifloxacin
    • Stass H. Metabolism and excretion of moxifloxacin. Drugs. 1999;58:231-2.
    • (1999) Drugs , vol.58 , pp. 231-232
    • Stass, H.1
  • 38
    • 84866642781 scopus 로고    scopus 로고
    • Poster presented at First International Moxifloxacin Symposium, Berlin, Germany
    • Dalhoff A. Dissociated resistance among fluoroquinolones. Poster presented at First International Moxifloxacin Symposium; 1999; Berlin, Germany.
    • (1999) Dissociated Resistance Among Fluoroquinolones
    • Dalhoff, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.