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Volumn 287, Issue 39, 2012, Pages 32338-32345

A scalable approach to prevent teratoma formation of human embryonic stem cells

Author keywords

[No Author keywords available]

Indexed keywords

CANCER RISK; CELL TYPES; DIFFERENTIATED CELLS; HERPES SIMPLEX VIRUS; HOMOLOGOUS RECOMBINATION; HUMAN CELLS; HUMAN EMBRYONIC STEM CELLS; HUMAN GENE THERAPY; PLURIPOTENCY; RENEWABLE SOURCES; SCALABLE APPROACH; THERAPEUTIC TARGETS; THYMIDINE KINASE; UNTRANSLATED REGIONS;

EID: 84866564584     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.383810     Document Type: Article
Times cited : (51)

References (36)
  • 1
    • 84856732029 scopus 로고    scopus 로고
    • Advancing stem cell biology toward stem cell therapeutics
    • Scadden, D., and Srivastava, A. (2012) Advancing stem cell biology toward stem cell therapeutics. Cell Stem Cell 10, 149-150
    • (2012) Cell Stem Cell , vol.10 , pp. 149-150
    • Scadden, D.1    Srivastava, A.2
  • 4
    • 79953058250 scopus 로고    scopus 로고
    • The tumorigenicity of human embryonic and induced pluripotent stem cells
    • Ben-David, U., and Benvenisty, N. (2011) The tumorigenicity of human embryonic and induced pluripotent stem cells. Nat. Rev. Cancer 11, 268-277
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 268-277
    • Ben-David, U.1    Benvenisty, N.2
  • 5
    • 78049239513 scopus 로고    scopus 로고
    • Teratomas from pluripotent stem cells: A clinical hurdle
    • Fong, C. Y., Gauthaman, K., and Bongso, A. (2010) Teratomas from pluripotent stem cells: A clinical hurdle. J. Cell. Biochem. 111, 769-781
    • (2010) J. Cell. Biochem. , vol.111 , pp. 769-781
    • Fong, C.Y.1    Gauthaman, K.2    Bongso, A.3
  • 6
    • 69249143719 scopus 로고    scopus 로고
    • MAb 84, a mcytotoxic antibody that kills undifferentiated human embryonic stem cells via oncosis
    • Tan, H. L., Fong, W. J., Lee, E. H., Yap, M., and Choo, A. (2009) mAb 84, a mcytotoxic antibody that kills undifferentiated human embryonic stem cells via oncosis. Stem Cells 27, 1792-1801
    • (2009) Stem Cells , vol.27 , pp. 1792-1801
    • Tan, H.L.1    Fong, W.J.2    Lee, E.H.3    Yap, M.4    Choo, A.5
  • 7
    • 48349106268 scopus 로고    scopus 로고
    • Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin-like protein-1
    • Choo, A. B., Tan, H. L., Ang, S. N., Fong, W. J., Chin, A., Lo, J., Zheng, L., Hentze, H., Philp, R. J., Oh, S. K., and Yap, M. (2008) Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin-like protein-1. Stem Cells 26, 1454-1463
    • (2008) Stem Cells , vol.26 , pp. 1454-1463
    • Choo, A.B.1    Tan, H.L.2    Ang, S.N.3    Fong, W.J.4    Chin, A.5    Lo, J.6    Zheng, L.7    Hentze, H.8    Philp, R.J.9    Oh, S.K.10    Yap, M.11
  • 8
    • 0031004717 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human podocalyxin-like protein
    • DOI 10.1074/jbc.272.25.15708
    • Kershaw, D. B., Beck, S. G., Wharram, B. L., Wiggins, J. E., Goyal, M., Thomas, P. E., and Wiggins, R. C. (1997) Molecular cloning and characterization of human podocalyxin-like protein. Orthologous relationship to rabbit PCLP1 and rat podocalyxin. J. Biol. Chem. 272, 15708-15714 (Pubitemid 27265543)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.25 , pp. 15708-15714
    • Kershaw, D.B.1    Beck, S.G.2    Wharram, B.L.3    Wiggins, J.E.4    Goyal, M.5    Thomas, P.E.6    Wiggins, R.C.7
  • 10
    • 69149103254 scopus 로고    scopus 로고
    • Roles and regulation of Thy-1, a context-dependent modulator of cell phenotype
    • Bradley, J. E., Ramirez, G., and Hagood, J. S. (2009) Roles and regulation of Thy-1, a context-dependent modulator of cell phenotype. BioFactors 35, 258-265
    • (2009) BioFactors , vol.35 , pp. 258-265
    • Bradley, J.E.1    Ramirez, G.2    Hagood, J.S.3
  • 11
    • 0032387839 scopus 로고    scopus 로고
    • CD30: Expression and function in health and disease
    • DOI 10.1006/smim.1998.0156
    • Horie, R., and Watanabe, T. (1998) CD30: Expression and function in health and disease. Semin. Immunol. 10, 457-470 (Pubitemid 28564375)
    • (1998) Seminars in Immunology , vol.10 , Issue.6 , pp. 457-470
    • Horie, R.1    Watanabe, T.2
  • 12
    • 0027199142 scopus 로고
    • Molecular cloning of the mouse equivalent of CD9 antigen
    • DOI 10.1016/0049-3848(93)90162-H
    • Rubinstein, E., Billard, M., Plaisance, S., Prenant, M., and Boucheix, C. (1993) Molecular cloning of the mouse equivalent of CD9 antigen. Thromb. Res. 71, 377-383 (Pubitemid 23244326)
    • (1993) Thrombosis Research , vol.71 , Issue.5 , pp. 377-383
    • Rubinstein, E.1    Billard, M.2    Plaisance, S.3    Prenant, M.4    Boucheix, C.5
  • 13
    • 0035103077 scopus 로고    scopus 로고
    • The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans
    • DOI 10.1046/j.1365-2567.2001.01163.x
    • Wright, G. J., Jones, M., Puklavec, M. J., Brown, M. H., and Barclay, A. N. (2001) The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans. Immunology 102, 173-179 (Pubitemid 32217509)
    • (2001) Immunology , vol.102 , Issue.2 , pp. 173-179
    • Wright, G.J.1    Jones, M.2    Puklavec, M.J.3    Brown, M.H.4    Barclay, A.N.5
  • 14
    • 19544386310 scopus 로고    scopus 로고
    • Teratoma formation leads to failure of treatment for type I diabetes using embryonic stem cell-derived insulin-producing cells
    • Fujikawa, T., Oh, S. H., Pi, L., Hatch, H. M., Shupe, T., and Petersen, B. E. (2005) Teratoma formation leads to failure of treatment for type I diabetes using embryonic stem cell-derived insulin-producing cells. Am. J. Pathol. 166, 1781-1791 (Pubitemid 40734401)
    • (2005) American Journal of Pathology , vol.166 , Issue.6 , pp. 1781-1791
    • Fujikawa, T.1    Oh, S.-H.2    Pi, L.3    Hatch, H.M.4    Shupe, T.5    Petersen, B.E.6
  • 15
    • 33749843288 scopus 로고    scopus 로고
    • Herpes simplex virus 1 (HSV-1) for cancer treatment
    • DOI 10.1038/sj.cgt.7700946, PII 7700946
    • Shen, Y., and Nemunaitis, J. (2006) Herpes simplex virus 1 (HSV-1) for cancer treatment. Cancer Gene Ther. 13, 975-992 (Pubitemid 44564734)
    • (2006) Cancer Gene Therapy , vol.13 , Issue.11 , pp. 975-992
    • Shen, Y.1    Nemunaitis, J.2
  • 16
    • 46749159104 scopus 로고    scopus 로고
    • Neuron-like differentiation and selective ablation of undifferentiated embryonic stem cells containing suicide gene with Oct-4 promoter
    • Hara, A., Aoki, H., Taguchi, A., Niwa, M., Yamada, Y., Kunisada, T., and Mori, H. (2008) Neuron-like differentiation and selective ablation of undifferentiated embryonic stem cells containing suicide gene with Oct-4 promoter. Stem Cells Dev. 17, 619-627
    • (2008) Stem Cells Dev. , vol.17 , pp. 619-627
    • Hara, A.1    Aoki, H.2    Taguchi, A.3    Niwa, M.4    Yamada, Y.5    Kunisada, T.6    Mori, H.7
  • 17
    • 0038700553 scopus 로고    scopus 로고
    • Selective ablation of human embryonic stem cells expressing a "suicide" gene
    • Schuldiner, M., Itskovitz-Eldor, J., and Benvenisty, N. (2003) Selective ablation of human embryonic stem cells expressing a "suicide" gene. Stem Cells 21, 257-265 (Pubitemid 36623167)
    • (2003) Stem Cells , vol.21 , Issue.3 , pp. 257-265
    • Schuldiner, M.1    Itskovitz-Eldor, J.2    Benvenisty, N.3
  • 19
    • 49149121054 scopus 로고    scopus 로고
    • Oct4 expression revisited: Potential pitfalls for data misinterpretation in stem cell research
    • Liedtke, S., Stephan, M., and Kögler, G. (2008) Oct4 expression revisited: Potential pitfalls for data misinterpretation in stem cell research. Biol. Chem. 389, 845-850
    • (2008) Biol. Chem. , vol.389 , pp. 845-850
    • Liedtke, S.1    Stephan, M.2    Kögler, G.3
  • 20
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • DOI 10.1016/S0092-8674(03)00393-3
    • Mitsui, K., Tokuzawa, Y., Itoh, H., Segawa, K., Murakami, M., Takahashi, K., Maruyama, M., Maeda, M., and Yamanaka, S. (2003) The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113, 631-642 (Pubitemid 36694188)
    • (2003) Cell , vol.113 , Issue.5 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3    Segawa, K.4    Murakami, M.5    Takahashi, K.6    Maruyama, M.7    Maeda, M.8    Yamanaka, S.9
  • 21
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • DOI 10.1016/S0092-8674(03)00392-1
    • Chambers, I., Colby, D., Robertson, M., Nichols, J., Lee, S., Tweedie, S., and Smith, A. (2003) Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113, 643-655 (Pubitemid 36694189)
    • (2003) Cell , vol.113 , Issue.5 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3    Nichols, J.4    Lee, S.5    Tweedie, S.6    Smith, A.7
  • 22
    • 27644448817 scopus 로고    scopus 로고
    • The pluripotency homeobox gene NANOG is expressed in human germ cell tumors
    • DOI 10.1002/cncr.21435
    • Hart, A. H., Hartley, L., Parker, K., Ibrahim, M., Looijenga, L. H., Pauchnik, M., Chow, C. W., and Robb, L. (2005) The pluripotency homeobox gene NANOGis expressed in human germ cell tumors. Cancer 104, 2092-2098 (Pubitemid 41579954)
    • (2005) Cancer , vol.104 , Issue.10 , pp. 2092-2098
    • Hart, A.H.1    Hartley, L.2    Parker, K.3    Ibrahim, M.4    Looijenga, L.H.J.5    Pauchnik, M.6    Chow, C.W.7    Robb, L.8
  • 24
    • 79551635114 scopus 로고    scopus 로고
    • NANOGinduction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis
    • Kohler, E. E., Cowan, C. E., Chatterjee, I., Malik, A. B., and Wary, K. K. (2011)NANOGinduction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis. Blood 117, 1761-1769
    • (2011) Blood , vol.117 , pp. 1761-1769
    • Kohler, E.E.1    Cowan, C.E.2    Chatterjee, I.3    Malik, A.B.4    Wary, K.K.5
  • 25
    • 79952955745 scopus 로고    scopus 로고
    • +, and SOX2- Mesenchymal cells from peripheral blood of a diabetes mellitus patient
    • +, and SOX2- mesenchymal cells from peripheral blood of a diabetes mellitus patient. Hum. Cell 24, 51-55
    • (2011) Hum. Cell , vol.24 , pp. 51-55
    • Potdar, P.D.1    D'Souza, S.B.2
  • 26
    • 73049105546 scopus 로고    scopus 로고
    • Modeling disease in human ESCs using an efficient BAC-based homologous recombination system
    • Song, H., Chung, S. K., and Xu, Y. (2010) Modeling disease in human ESCs using an efficient BAC-based homologous recombination system. Cell Stem Cell 6, 80-89
    • (2010) Cell Stem Cell , vol.6 , pp. 80-89
    • Song, H.1    Chung, S.K.2    Xu, Y.3
  • 27
    • 0035487293 scopus 로고    scopus 로고
    • Recombineering: A powerful new tool for mouse functional genomics
    • DOI 10.1038/35093556
    • Copeland, N. G., Jenkins, N. A., and Court, D. L. (2001) Recombineering: A powerful new tool for mouse functional genomics. Nat. Rev. Genet. 2, 769-779 (Pubitemid 33685574)
    • (2001) Nature Reviews Genetics , vol.2 , Issue.10 , pp. 769-779
    • Copeland, N.G.1    Jenkins, N.A.2    Court, D.L.3
  • 28
    • 34247329362 scopus 로고    scopus 로고
    • p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM
    • DOI 10.1038/ncb1571, PII NCB1571
    • Song, H., Hollstein, M., and Xu, Y. (2007) p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM. Nat. Cell Biol. 9, 573-580 (Pubitemid 46696539)
    • (2007) Nature Cell Biology , vol.9 , Issue.5 , pp. 573-580
    • Song, H.1    Hollstein, M.2    Xu, Y.3
  • 31
    • 0035300565 scopus 로고    scopus 로고
    • Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing
    • Black, M. E., Kokoris, M. S., and Sabo, P. (2001) Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing. Cancer Res. 61, 3022-3026 (Pubitemid 32691949)
    • (2001) Cancer Research , vol.61 , Issue.7 , pp. 3022-3026
    • Black, M.E.1    Kokoris, M.S.2    Sabo, P.3
  • 32
    • 34250743850 scopus 로고    scopus 로고
    • Human reporter genes: potential use in clinical studies
    • DOI 10.1016/j.nucmedbio.2007.05.009, PII S0969805107001382
    • Serganova, I., Ponomarev, V., and Blasberg, R. (2007) Human reporter genes: Potential use in clinical studies. Nucl. Med. Biol. 34, 791-807 (Pubitemid 47503822)
    • (2007) Nuclear Medicine and Biology , vol.34 , Issue.7 , pp. 791-807
    • Serganova, I.1    Ponomarev, V.2    Blasberg, R.3
  • 33
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson, J. A., Itskovitz-Eldor, J., Shapiro, S. S., Waknitz, M. A., Swiergiel, J. J., Marshall, V. S., and Jones, J. M. (1998) Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147 (Pubitemid 28516247)
    • (1998) Science , vol.282 , Issue.5391 , pp. 1145-1147
    • Thomson, J.A.1
  • 34
    • 79955799022 scopus 로고    scopus 로고
    • Self-renewal and scalability of human embryonic stem cells for human therapy
    • Fu, X., and Xu, Y. (2011) Self-renewal and scalability of human embryonic stem cells for human therapy. Regen. Med. 6, 327-334
    • (2011) Regen. Med. , vol.6 , pp. 327-334
    • Fu, X.1    Xu, Y.2
  • 35
    • 0034933929 scopus 로고    scopus 로고
    • Ganciclovir: An update of its use in the prevention of cytomegalovirus infection and disease in transplant recipients
    • McGavin, J. K., and Goa, K. L. (2001) Ganciclovir: An update of its use in the prevention of cytomegalovirus infection and disease in transplant recipients. Drugs 61, 1153-1183 (Pubitemid 32661232)
    • (2001) Drugs , vol.61 , Issue.8 , pp. 1153-1183
    • McGavin, J.K.1    Goa, K.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.