Differential diagnosis of preeclampsia: Remember the soluble Fms-like tyrosine kinase 1/placental growth factor ratio

Hypertension

Volumn 60, Issue 4, 2012, Pages 884-890

  Verdonk, Koen ^a   Visser, Willy ^b   Russcher, Henk ^c   Danser, A H Jan ^a   Steegers, Eric A P ^b   Van Den Meiracker, Anton H ^a  

^a Department of Internal Medicine   (Netherlands)

^b Division of Obstetrics and Prenatal Medicine   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACENOCOUMAROL; ALANINE AMINOTRANSFERASE; ALBUMIN; ANTINUCLEAR ANTIBODY; ASPARTATE AMINOTRANSFERASE; AZATHIOPRINE; BILIRUBIN; C REACTIVE PROTEIN; CARBASALATE CALCIUM; CREATININE; DOUBLE STRANDED DNA ANTIBODY; FUROSEMIDE; HAPTOGLOBIN; HEMOGLOBIN; HYDROXYCHLOROQUINE; LABETALOL; LACTATE DEHYDROGENASE; LOW MOLECULAR WEIGHT HEPARIN; LUPUS ANTICOAGULANT; METHYLDOPA; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NICARDIPINE; PHOSPHOLIPID ANTIBODY; PLACENTAL GROWTH FACTOR; PREDNISONE; RO ANTIBODY; UNINDEXED DRUG; URIC ACID; VASCULOTROPIN RECEPTOR 1;

ADULT; ANTIBODY TITER; ARTICLE; AUTOIMMUNE HEPATITIS; BODY WEIGHT; BREATHING RATE; CASE REPORT; CENTRAL VENOUS PRESSURE; COMPUTER ASSISTED TOMOGRAPHY; CREATININE BLOOD LEVEL; DEEP VEIN THROMBOSIS; DIFFERENTIAL DIAGNOSIS; DRUG PULSE THERAPY; DYSPNEA; ECHOCARDIOGRAPHY; ESOPHAGUS VARICES; FEMALE; GESTATIONAL AGE; HEART AUSCULTATION; HEART RIGHT VENTRICLE PRESSURE; HUMAN; HYPERSPLENISM; HYPERTENSION; IMMUNOSUPPRESSIVE TREATMENT; INFANT; LABORATORY TEST; LEG EDEMA; LIGATION; LIVER CIRRHOSIS; LUPUS ERYTHEMATOSUS NEPHRITIS; MALE; MEDICAL HISTORY; MITRAL VALVE REGURGITATION; NEPHROTIC SYNDROME; OXYGEN SATURATION; PHYSICAL EXAMINATION; PLEURA EFFUSION; PORTAL HYPERTENSION; PORTAL VEIN THROMBOSIS; PREECLAMPSIA; PREGNANCY OUTCOME; PREGNANCY TERMINATION; PRIORITY JOURNAL; PROTEINURIA; PULMONARY HYPERTENSION; PULSE RATE; RAYNAUD PHENOMENON; ROOM TEMPERATURE; SPLENOMEGALY; THROMBOCYTE COUNT; THROMBOCYTOPENIA;

ADULT; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY PROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 84866559742     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.112.201459     Document Type: Article

References (43)

1. Steegers EA, von Dadelszen P, Duvekot JJ, Pijnenborg R. Pre-eclampsia. Lancet. 2010;376:631-644.
2. Baer AN, Witter FR, Petri M. Lupus and pregnancy. Obstet Gynecol Surv. 2011;66:639-653.
3. Smyth A, Oliveira GH, Lahr BD, Bailey KR, Norby SM, Garovic VD. A systematic review and meta-analysis of pregnancy outcomes in patients with systemic lupus erythematosus and lupus nephritis. Clin J Am Soc Nephrol. 2010;5:2060-2068.
4. Verlohren S, Stepan H, Dechend R. Angiogenic growth factors in the diagnosis and prediction of pre-eclampsia. Clin Sci (Lond). 2012;122:43-52.
5. Coolman M, Timmermans S, de Groot CJ, Russcher H, Lindemans J, Hofman A, Geurts-Moespot AJ, Sweep FC, Jaddoe VV, Steegers EA. Angiogenic and fbrinolytic factors in blood during the frst half of pregnancy and adverse pregnancy outcomes. Obstet Gynecol. 2012;119:1190-1200.
6. Verlohren S, Herraiz I, Lapaire O, Schlembach D, Moertl M, Zeisler H, Calda P, Holzgreve W, Galindo A, Engels T, Denk B, Stepan H. The sft-1/plgf ratio in different types of hypertensive pregnancy disorders and its prognostic potential in preeclamptic patients. Am J Obstet Gynecol. 2012;206:58, e51-e58.
7. Verlohren S, Galindo A, Schlembach D, Zeisler H, Herraiz I, Moertl MG, Pape J, Dudenhausen JW, Denk B, Stepan H. An automated method for the determination of the sft-1/pigf ratio in the assessment of preeclamp-sia. Am J Obstet Gynecol. 2010;202:161, e161-161, e111.
8. Rana S, Powe CE, Salahuddin S, Verlohren S, Perschel FH, Levine RJ, Lim KH, Wenger JB, Thadhani R, Karumanchi SA. Angiogenic factors and the risk of adverse outcomes in women with suspected preeclampsia. Circulation. 2012;125:911-919.
9. Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA. Circulating angiogenic factors and the risk of pre-eclampsia. N Engl J Med. 2004;350:672-683.
10. Levine RJ, Lam C, Qian C, Yu KF, Maynard SE, Sachs BP, Sibai BM, Epstein FH, Romero R, Thadhani R, Karumanchi SA, Group CS. Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med. 2006;355:992-1005.
11. Sunderji S, Gaziano E, Wothe D, Rogers LC, Sibai B, Karumanchi SA, Hodges-Savola C. Automated assays for SVEGF r1 and plgf as an aid in the diagnosis of preterm preeclampsia: a prospective clinical study. Am J Obstet Gynecol. 2010;202:40, e41-e47.
12. Schiettecatte J, Russcher H, Anckaert E, Mees M, Leeser B, Tirelli AS, Fiedler GM, Luthe H, Denk B, Smitz J. Multicenter evaluation of the frst automated elecsys sft-1 and plgf assays in normal pregnancies and pre-eclampsia. Clin Biochem. 2010;43:768-770.
13. Joshi D, James A, Quaglia A, Westbrook RH, Heneghan MA. Liver disease in pregnancy. Lancet. 2010;375:594-605.
14. Aggarwal N, Sawnhey H, Suril V, Vasishta K, Jha M, Dhiman RK. Pregnancy and cirrhosis of the liver. Aust N Z J Obstet Gynaecol. 1999;39:503-506.
15. Westbrook RH, Yeoman AD, Kriese S, Heneghan MA. Outcomes of pregnancy in women with autoimmune hepatitis. J Autoimmun. 2012;38: J239-J244.
16. Magann EF, Martin JN, Jr. Twelve steps to optimal management of hellp syndrome. Clin Obstet Gynecol. 1999;42:532-550.
17. Levine JS, Branch DW, Rauch J. The antiphospholipid syndrome. N Engl J Med. 2002;346:752-763.
18. do Prado AD, Piovesan DM, Staub HL, Horta BL. Association of anti-cardiolipin antibodies with preeclampsia: a systematic review and meta-analysis. Obstet Gynecol. 2010;116:1433-1443.
19. Moroni G, Quaglini S, Banf G, Caloni M, Finazzi S, Ambroso G, Como G, Ponticelli C. Pregnancy in lupus nephritis. Am J Kidney Dis. 2002;40:713-720.
20. Petri M, Howard D, Repke J. Frequency of lupus fare in pregnancy: the Hopkins Lupus Pregnancy Center experience. Arthritis Rheum. 1991;34:1538-1545.
21. Ostensen M, Villiger PM, Forger F. Interaction of pregnancy and autoimmune rheumatic disease. Autoimmun Rev. 2012;11:A437-A446.
22. Saavedra MA, Cruz-Reyes C, Vera-Lastra O, Romero GT, Cruz-Cruz P, Arias-Flores R, Jara LJ. Impact of previous lupus nephritis on maternal and fetal outcomes during pregnancy. Clin Rheumatol. 2012;31:813-819.
23. Maynard SE MJ, Merchan J, Lim KH, Li J, Mondal S, Libermann TA, Morgan JP, Sellke FW, Stillman IE, Epstein FH, Sukhatme VP, Karumanchi SA. Excess placental soluble fms-like tyrosine kinase 1 (sft1) may contribute to endothelial dysfunction, hypertension, and pro-teinuria in preeclampsia. J Clin Invest. 2003;111:649-658.
24. Makris A, Thornton C, Thompson J, Thomson S, Martin R, Ogle R, Waugh R, McKenzie P, Kirwan P, Hennessy A. Uteroplacental ischemia results in proteinuric hypertension and elevated sft-1. Kidney Int. 2007;71:977-984.
25. Taylor RN, Grimwood J, Taylor RS, McMaster MT, Fisher SJ, North RA. Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnancies. Am J Obstet Gynecol. 2003;188:177-182.
26. Ohkuchi A, Hirashima C, Suzuki H, Takahashi K, Yoshida M, Matsubara S, Suzuki M. Evaluation of a new and automated electrochemilumines-cence immunoassay for plasma sft-1 and plgf levels in women with pre-eclampsia. Hypertens Res. 2010;33:422-427.
27. Knudsen UB, Kronborg CS, von Dadelszen P, Kupfer K, Lee S-W, Vittinghus E, Allen JG, Redman CW. A single rapid point-of-care placen-tal growth factor determination as an aid in the diagnosis of preeclampsia. Pregnancy Hypertens. 2012;2:8-15.
28. Noori M, Donald AE, Angelakopoulou A, Hingorani AD, Williams DJ. Prospective study of placental angiogenic factors and maternal vascular function before and after preeclampsia and gestational hypertension. Circulation. 2010;122:478-487.
29. Rana S, Karumanchi SA, Levine RJ, Venkatesha S, Rauh-Hain JA, Tamez H, Thadhani R. Sequential changes in antiangiogenic factors in early pregnancy and risk of developing preeclampsia. Hypertension. 2007;50:137-142.
30. Perni U, Sison C, Sharma V, Helseth G, Hawfeld A, Suthanthiran M, August P. Angiogenic factors in superimposed preeclampsia: a longitudinal study of women with chronic hypertension during pregnancy. Hypertension. 2012;59:740-746.
31. Hrycek A, Janowska J, Cieslik P. Selected angiogenic cytokines in systemic lupus erythematosus patients. Autoimmunity. 2009;42:459-466.
32. Robak E, Sysa-Jedrzejewska A, Robak T. Vascular endothelial growth factor and its soluble receptors VEGFR-1 and VEGFR-2 in the serum of patients with systemic lupus erythematosus. Mediators Infamm. 2003;12:293-298.
33. Qazi U, Lam C, Karumanchi SA, Petri M. Soluble fms-like tyrosine kinase associated with preeclampsia in pregnancy in systemic lupus ery-thematosus. J Rheumatol. 2008;35:631-634.
34. Rosenberg VA, Buhimschi IA, Lockwood CJ, Paidas MJ, Dulay AT, Ramma W, Abdel-Razeq SS, Zhao G, Ahmad S, Ahmed A, Buhimschi CS. Heparin elevates circulating soluble fms-like tyrosine kinase-1 immunoreactivity in pregnant women receiving anticoagulation therapy. Circulation. 2011;124:2543-2553.
35. Searle J, Mockel M, Gwosc S, Datwyler SA, Qadri F, Albert GI, Holert F, Isbruch A, Klug L, Muller DN, Dechend R, Muller R, Vollert JO, Slagman A, Mueller C, Herse F. Heparin strongly induces soluble fms-like tyrosine kinase 1 release in vivo and in vitro: brief report. Arterioscler Thromb Vasc Biol. 2011;31:2972-2974.
36. Chaiworapongsa T, Espinoza J, Gotsch F, Kim YM, Kim GJ, Goncalves LF, Edwin S, Kusanovic JP, Erez O, Than NG, Hassan SS, Romero R. The maternal plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated in SGA and the magnitude of the increase relates to doppler abnormalities in the maternal and fetal circulation. J Matern Fetal Neonatal Med. 2008;21:25-40.
37. Shibata E, Rajakumar A, Powers RW, Larkin RW, Gilmour C, Bodnar LM, Crombleholme WR, Ness RB, Roberts JM, Hubel CA. Soluble fms-like tyrosine kinase 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates: relationship to circulating placental growth factor. J Clin Endocrinol Metab. 2005;90:4895-4903.
38. Wallner W, Sengenberger R, Strick R, Strissel PL, Meurer B, Beckmann MW, Schlembach D. Angiogenic growth factors in maternal and fetal serum in pregnancies complicated by intrauterine growth restriction. Clin Sci (Lond). 2007;112:51-57.
39. Schlembach D, Wallner W, Sengenberger R, Stiegler E, Mortl M, Beckmann MW, Lang U. Angiogenic growth factor levels in maternal and fetal blood: correlation with doppler ultrasound parameters in pregnancies complicated by pre-eclampsia and intrauterine growth restriction. Ultrasound Obstet Gynecol. 2007;29:407-413.
40. Carty DM, Siwy J, Brennand JE, Zurbig P, Mullen W, Franke J, McCulloch JW, Roberts CT, North RA, Chappell LC, Mischak H, Poston L, Dominiczak AF, Delles C. Urinary proteomics for prediction of pre-eclampsia. Hypertension. 2011;57:561-569.
41. Anderson UD, Olsson MG, Kristensen KH, Akerstrom B, Hansson SR. Review: biochemical markers to predict preeclampsia. Placenta. 2012;33(suppl):S42-S47.
42. Thadhani R, Kisner T, Hagmann H, Bossung V, Noack S, Schaarschmidt W, Jank A, Kribs A, Cornely OA, Kreyssig C, Hemphill L, Rigby AC, Khedkar S, Lindner TH, Mallmann P, Stepan H, Karumanchi SA, Benzing T. Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia. Circulation. 2011;124:940-950.
43. Li Z, Zhang Y, Ying Ma J, Kapoun AM, Shao Q, Kerr I, Lam A, O'Young G, Sannajust F, Stathis P, Schreiner G, Karumanchi SA, Protter AA, Pollitt NS. Recombinant vascular endothelial growth factor 121 attenuates hypertension and improves kidney damage in a rat model of preeclampsia. Hypertension. 2007;50:686-692.