How to connect an IgE-driven response with CTL activity?

Cancer Immunology, Immunotherapy

Volumn 61, Issue 9, 2012, Pages 1521-1525

  Platzer, Barbara ^a,b   Dehlink, Eleonora ^c   Turley, Shannon J ^b,d   Fiebiger, Edda ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Department of Pediatrics and Adolescent Medicine   (Austria)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

AllergoOncology; Antigen presentation; CD23; Dendritic cells; Fc receptors; Fc RI

Indexed keywords

CD23 ANTIGEN; FC EPSILON RECEPTOR I; FC EPSILON RECEPTOR II; FC RECEPTOR; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; CELL ACTIVITY; CELL DIFFERENTIATION; CONFERENCE PAPER; CROSS PRESENTATION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; HUMAN; IMMUNE RESPONSE; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; TUMOR IMMUNITY;

ANIMALS; ANTIGEN PRESENTATION; CROSS-PRIMING; DENDRITIC CELLS; HUMANS; IMMUNOGLOBULIN E; RECEPTORS, IGG; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84866555431     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-011-1127-y     Document Type: Conference Paper

References (38)

1. Amigorena S, Savina A (2010) Intracellular mechanisms of antigen cross presentation in dendritic cells. Curr Opin Immunol 22(1):109-117
2. Bevan MJ (2006) Cross-priming. Nat Immunol 7(4):363-365
3. Kurts C, Robinson BW, Knolle PA (2010) Cross-priming in health and disease. Nat Rev Immunol 10(6):403-414
4. Robson NC, Hoves S, Maraskovsky E, Schnurr M (2010) Presentation of tumour antigens by dendritic cells and challenges faced. Curr Opin Immunol 22(1):137-144
5. Segura E, Villadangos JA (2009) Antigen presentation by dendritic cells in vivo. Curr Opin Immunol 21(1):105-110
6. Vyas JM, Van der Veen AG, Ploegh HL (2008) The known unknowns of antigen processing and presentation. Nat Rev Immunol 8(8):607-618
7. Baker K, Qiao SW, Kuo TT, Aveson VG, Platzer B, Andersen JT, Sandlie I, Chen Z, de Haar C, Lencer WI, Fiebiger E, Blumberg RS (2011) Neonatal Fc receptor for IgG (FcRn) regulates crosspresentation of IgG immune complexes by CD8-CD11b+ dendritic cells. Proc Natl Acad Sci USA 108(24):9927-9932
8. den Haan JM, Bevan MJ (2002) Constitutive versus activationdependent cross-presentation of immune complexes by CD8(+) and CD8(!) dendritic cells in vivo. J Exp Med 196(6):817-827
9. Burgdorf S, Kurts C (2008) Endocytosis mechanisms and the cell biology of antigen presentation. Curr Opin Immunol 20(1):89-95
10. Savina A, Jancic C, Hugues S, Guermonprez P, Vargas P, Moura IC, Lennon-Dumenil AM, Seabra MC, Raposo G, Amigorena S (2006) NOX2 controls phagosomal pH to regulate antigen processing during cross presentation by dendritic cells. Cell 126(1):205-218 (Pubitemid 44026552)
11. van Montfoort N, Camps MG, Khan S, Filippov DV, Weterings JJ, GriYth JM, Geuze HJ, van Hall T, Verbeek JS, Melief CJ, Ossendorp F (2009) Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity. Proc Natl Acad Sci USA 106(16):6730-6735
12. Shrimpton RE, Butler M, Morel AS, Eren E, Hue SS, Ritter MA (2009) CD205 (DEC-205): a recognition receptor for apoptotic and necrotic self. Mol Immunol 46(6):1229-1239
13. Burgdorf S, Scholz C, Kautz A, Tampe R, Kurts C (2008) Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation. Nat Immunol 9(5):558-566 (Pubitemid 351560525)
14. Amigorena S, Bonnerot C (1999) Fc receptors for IgG and antigen presentation on MHC class I and class II molecules. Semin Immunol 11(6):385-390 (Pubitemid 30047500)
15. de Jong JM, Schuurhuis DH, Ioan-Facsinay A, van der Voort EI, Huizinga TW, Ossendorp F, Toes RE, Verbeek JS (2006) Murine Fc receptors for IgG are redundant in facilitating presentation of immune complex derived antigen to CD8+ T cells in vivo. Mol Immunol 43(13):2045-2050
16. Regnault A, Lankar D, Lacabanne V, Rodriguez A, Thery C, Rescigno M, Saito T, Verbeek S, Bonnerot C, Ricciardi-Castagnoli P, Amigorena S (1999) Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization. J Exp Med 189(2):371-380 (Pubitemid 29063258)
17. Harbers SO, Crocker A, Catalano G, D'Agati V, Jung S, Desai DD, Clynes R (2007) Antibody-enhanced cross-presentation of self antigen breaks T cell tolerance. J Clin Invest 117(5):1361-1369 (Pubitemid 46718424)
18. Gould HJ, Sutton BJ (2008) IgE in allergy and asthma today. Nat Rev Immunol 8(3):205-217 (Pubitemid 351323292)
19. Maurer D, Fiebiger E, Ebner C, Reininger B, Fischer GF, Wichlas S, Jouvin M-H, Schmitt-Egenolf M, Kraft D, Kinet J-P, Stingl G (1996) Peripheral blood dendritic cells express FceRI as a complex composed of FceRIa-and FceRIg-chains and can use this receptor for IgE-mediated allergen presentation. J Immunol 157:607-613
20. Maurer D, Fiebiger E, Reininger B, WolV-Winiski B, Jouvin M-H, Kilgus O, Kinet J-P, Stingl G (1994) Expression of functional high aYnity immunoglobulin E receptors (FceRI) on monocytes of atopic individuals. J Exp Med 179:745-750 (Pubitemid 24058765)
21. Grayson MH, Cheung D, RohlWng MM, Kitchens R, Spiegel DE, Tucker J, Battaile JT, Alevy Y, Yan L, Agapov E, Kim EY, Holtzman MJ (2007) Induction of high-aYnity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia. J Exp Med 204(11):2759-2769 (Pubitemid 350044797)
22. Hammad H, Plantinga M, Deswarte K, Pouliot P, Willart MA, Kool M, Muskens F, Lambrecht BN (2010) InXammatory dendritic cells-not basophils-are necessary and suYcient for induction of Th2 immunity to inhaled house dust mite allergen. J Exp Med 207(10):2097-2111
23. Platzer B, Ruiter F, van der Mee J, Fiebiger E (2011) Soluble IgE receptors-Elements of the IgE network. Immunol Lett. doi:10.1016/j.imlet.2011. 08.004
24. Kraft S, Kinet JP (2007) New developments in FcepsilonRI regulation, function and inhibition. Nat Rev Immunol 7(5):365-378 (Pubitemid 46674486)
25. Ravetch JV, Kinet JP (1991) Fc receptors. Annu Rev Immunol 9:457-492
26. Maurer D, Stingl G (1995) Immunoglobulin E-binding structures on antigen-presenting cells present in skin and blood. J Invest Dermatol 104(5):707-710
27. Untersmayr E, Bises G, Starkl P, Bevins CL, Scheiner O, Boltz-Nitulescu G, Wrba F, Jensen-Jarolim E (2010) The high aYnity IgE receptor Fc epsilonRI is expressed by human intestinal epithelial cells. PLoS One 5(2):e9023. doi:10.1371/journal.pone. 0009023
28. Hasegawa S, Pawankar R, Suzuki K, Nakahata T, Furukawa S, Okumura K, Ra C (1999) Functional expression of the high aYnity receptor for IgE (FcepsilonRI) in human platelets and its' intracellular expression in human megakaryocytes. Blood 93(8):2543-2551 (Pubitemid 29181186)
29. Andoh T, Kuraishi Y (2004) Expression of Fc epsilon receptor I on primary sensory neurons in mice. Neuroreport 15(13):2029-2031. doi:00001756-200409150- 00007 (Pubitemid 39281741)
30. Kubota T, Mukai K, Minegishi Y, Karasuyama H (2006) DiVerent stabilities of the structurally related receptors for IgE and IgG on the cell surface are determined by length of the stalk region in their alpha-chains. J Immunol 176(11):7008-7014 (Pubitemid 43787881)
31. Maurer D, Fiebiger E, Reininger B, Ebner C, Petzelbauer P, Shi GP, Chapman HA, Stingl G (1998) Fc epsilon receptor I on dendritic cells delivers IgE-bound multivalent antigens into a cathepsin S-dependent pathway of MHC class II presentation. J Immunol 161(6):2731-2739 (Pubitemid 28425691)
32. Kilmon MA, Ghirlando R, Strub MP, Beavil RL, Gould HJ, Conrad DH (2001) Regulation of IgE production requires oligomerization of CD23. J Immunol 167(6):3139-3145 (Pubitemid 32852552)
33. Mudde GC, Bheekha R, Bruijnzeel-Koomen CA (1995) Consequences of IgE/CD23-mediated antigen presentation in allergy. Immunol Today 16(8):380-383
34. Santamaria LF, Bheekha R, van Reijsen FC, Perez Soler MT, Suter M, Bruijnzeel-Koomen CA, Mudde GC (1993) Antigen focusing by speciWc monomeric immunoglobulin E bound to CD23 on Epstein-Barr virus-transformed B cells. Hum Immunol 37(1):23-30 (Pubitemid 23221835)
35. Miyahara N, Swanson BJ, Takeda K, Taube C, Miyahara S, Kodama T, Dakhama A, Ott VL, Gelfand EW (2004) EVector CD8+ T cells mediate inXammation and airway hyper-responsiveness. Nat Med 10(8):865-869 (Pubitemid 39070861)
36. Sallmann E, Reininger B, Brandt S, Duschek N, HoXehner E, Garner-Spitzer E, Platzer B, Dehlink E, Hammer M, Holcmann M, Oettgen HC, Wiedermann U, Sibilia M, Fiebiger E, Rot A, Maurer D (2011) High-AYnity IgE Receptors on Dendritic Cells Exacerbate Th2-Dependent InXammation. J Immunol 187(1):164-171
37. Jensen-Jarolim E, Achatz G, Turner MC, Karagiannis S, Legrand F, Capron M, Penichet ML, Rodriguez JA, Siccardi AG, Vangelista L, Riemer AB, Gould H (2008) AllergoOncology: the role of IgE-mediated allergy in cancer. Allergy 63(10):1255-1266
38. Dhodapkar KM, Krasovsky J, Williamson B, Dhodapkar MV (2002) Antitumor monoclonal antibodies enhance cross-presentation of cellular antigens and the generation of myeloma-speciWc killer T cells by dendritic cells. J Exp Med 195(1):125-133 (Pubitemid 34074502)