Influence of major cardiopulmonary surgery on serum levels of procalcitonin and other inflammatory markers

Anaesthesia and Intensive Care

Volumn 40, Issue 5, 2012, Pages 760-766

  Amin, D N ^a,b   Pruit, J C ^a   Schuetz, P ^a,c  

^a Morton Plant Hospital   (United States)

^b Critical Care Services   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Biomarker; C reactive protein; Cardiopulmonary surgery; Procalcitonin

Indexed keywords

PROCALCITONIN;

ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; BLOOD SAMPLING; CORONARY ARTERY BYPASS GRAFT; FEMALE; HEART SURGERY; HEART VALVE SURGERY; HUMAN; INFECTION; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PROTEIN BLOOD LEVEL; SENSITIVITY ANALYSIS; TREATMENT OUTCOME;

EID: 84866541729     PISSN: 0310057X     EISSN: 14480271     Source Type: Journal    
DOI: 10.1177/0310057x1204000502     Document Type: Article

References (27)

1. Laffey JG, Boylan JF, Cheng DC. The systemic inflammatory response to cardiac surgery: implications for the anesthesiologist. Anesthesiology 2002; 97:215-252.
2. Gogos CA, Drosou E, Bassaris HP, Skoutelis A. Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options. J Infect Dis 2000; 181:176-180.
3. Christ-Crain M, Muller B. Biomarkers in respiratory tract infections: diagnostic guides to antibiotic prescription, prognostic markers and mediators. Eur Respir J 2007; 30:556-573.
4. Schuetz P, Amin DN, Greenwald. Role of procalcitonin in managing adult patients with respiratory tract infections. Chest 2012; 141:1063-1073.
5. Schuetz P, Chiappa V, Briel M, Greenwald JL. Procalcitonin algorithms for antibiotic therapy decisions: a systematic review of randomized controlled trials and recommendations for clinical algorithms. Arch Intern Med 2011; 171:1322-1331.
6. Christ-Crain M, Jaccard-Stolz D, Bingisser R, Gencay MM, Huber PR, Tamm M et al. Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial. Lancet 2004; 363:600-607.
7. Christ-Crain M, Stolz D, Bingisser R, Muller C, Miedinger D, Huber PR et al. Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial. Am J Respir Crit Care Med 2006; 174:84-93.
8. Schuetz P, Christ-Crain M, Thomann R, Falconnier C, Wolbers M, Widmer I et al. Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial. JAMA 2009; 302:1059-1066.
9. Stolz D, Christ-Crain M, Bingisser R, Leuppi J, Miedinger D, Muller C et al. Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy. Chest 2007; 131:9-19.
10. Nobre V, Harbarth S, Graf JD, Rohner P, Pugin J. Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial. Am J Respir Crit Care Med 2008; 177:498-505.
11. Bouadma L, Luyt CE, Tubach F, Cracco C, Alvarez A, Schwebel C et al. Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial. Lancet 2010; 375:463-474.
12. Aouifi A, Piriou V, Bastien O, Blanc P, Bouvier H, Evans R et al. Usefulness of procalcitonin for diagnosis of infection in cardiac surgical patients. Crit Care Med 2000; 28:3171-3176.
13. Carboni GL, Fahrner R, Gazdhar A, Printzen G, Schmid RA, Hoksch B. Comparison of procalcitonin and CrP in the postoperative course after lung decortication. Eur J Cardiothorac Surg 2008; 33:777-780.
14. Dorge H, Schondube FA, Dorge P, Seipelt R, Voss M, Messmer BJ. Procalcitonin is a valuable prognostic marker in cardiac surgery but not specific for infection. Thorac Cardiovasc Surg 2003; 51:322-326.
15. Laifer G, Wasner M, Sendi P, Graber P, Gratzl O, Huber P et al. Dynamics of serum procalcitonin in patients after major neurosurgery. Clin Microbiol Infect 2005; 11:679-681.
16. Oberhofer D, Rumenjak V, Lazic J, Vucic N. Inflammatory indicators in patients after surgery of the large intestine. Acta Med Croatica 2006; 60:429-433.
17. Sponholz C, Sakr Y, Reinhart K, Brunkhorst F. Diagnostic value and prognostic implications of serum procalcitonin after cardiac surgery: a systematic review of the literature. Crit Care 2006; 10:R145.
18. Meisner M, Tschaikowsky K, Hutzler A, Schick C, Schuttler J. Postoperative plasma concentrations of procalcitonin after different types of surgery. Intensive Care Med 1998; 24:680-684.
19. Hunziker S, Hugle T, Schuchardt K, Groeschl I, Schuetz P, Mueller B et al. The value of serum procalcitonin level for differentiation of infectious from noninfectious causes of fever after orthopaedic surgery. J Bone Joint Surg Am 2010; 92:138-148.
20. Hochreiter M, Köhler T, Schweiger AM, Keck FS, Bein B, von Spiegel T et al. Procalcitonin to guide duration of antibiotic therapy in intensive care patients: a randomized prospective controlled trial. Crit Care 2009; 13:R83.
21. Celebi S, Koner O, Menda F, Balci H, Hatemi A, Korkut K et al. Procalcitonin kinetics in pediatric patients with systemic inflammatory response after open heart surgery. Intensive Care Med 2006; 32:881-887.
22. Skrak P, Kovacikova L, Kunovsky P. Procalcitonin, neopterin and C-reactive protein after pediatric cardiac surgery with cardiopulmonary bypass. Bratisl Lek Listy 2007; 108:501-505.
23. Madershahian N, Wittwer T, Strauch J, Wippermann J, Rahmanian P, Franke UF et al. Kinetic of procalcitonin in the early postoperative course following heart transplantation. J Card Surg 2008; 23:468-473.
24. Rosmarakis ES, Prapas SN, Rellos K, Michalopoulos A, Samonis G, Falagas ME. Nosocomial infections after off-pump coronary artery bypass surgery: frequency, characteristics, and risk factors. Interact Cardiovasc Thorac Surg 2007; 6:759-767.
25. Schuetz P, Albrich W, Christ-Crain M, Chastre J, Mueller B. Procalcitonin for guidance of antibiotic therapy. Expert Rev Anti Infect Ther 2010; 8:575-587.
26. Schuetz P, Christ-Crain M, Wolbers M, Schild U, Thomann R, Falconnier C et al. Procalcitonin guided antibiotic therapy and hospitalization in patients with lower respiratory tract infections: a prospective, multicenter, randomized controlled trial. BMC Health Serv Res 2007; 7:102.
27. Schuetz P, Christ-Crain M, Muller B. Procalcitonin and other biomarkers to improve assessment and antibiotic stewardship in infections - hope for hype? Swiss Med Wkly 2009; 139:318-326.