7-Nitro-4-(phenylthio)benzofurazan is a potent generator of superoxide and hydrogen peroxide

Archives of Toxicology

Volumn 86, Issue 10, 2012, Pages 1613-1625

  Patridge, Eric V ^a   Eriksson, Emma S E ^b,c   Penketh, Philip G ^a   Baumann, Raymond P ^a   Zhu, Rui ^a   Shyam, Krishnamurthy ^a   Eriksson, Leif A ^b,c   Sartorelli, Alan C ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Benzofurazan; Electrochemistry; Electrophilic stress; Oxidative stress; Reactive oxygen species

Indexed keywords

7 NITRO 4 (PHENYLTHIO)BENZOFURAZAN; BENZOFURAZAN DERIVATIVE; GLYCEROL; HYDROGEN PEROXIDE; JUGLONE; MENADIONE; OXYGEN; PLUMBAGIN; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOGLYCEROL; UNCLASSIFIED DRUG; URIC ACID;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL SURVIVAL; CYCLIC POTENTIOMETRY; DIFFERENTIAL PULSE POLAROGRAPHY; DRUG CYTOTOXICITY; ELECTROCHEMICAL ANALYSIS; ELECTROPHILICITY; LC 50; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; FEMALE; HYDROGEN PEROXIDE; LETHAL DOSE 50; LIPID PEROXIDATION; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; OXADIAZOLES; OXIDATION-REDUCTION; OXYGEN; REACTIVE OXYGEN SPECIES; SUPEROXIDES; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 84866538749     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0872-9     Document Type: Article

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