Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1

Cancer Chemotherapy and Pharmacology

Volumn 70, Issue 2, 2012, Pages 339-344

  Godbole, Abhijit M ^a,b   Purushottamachar, Puranik ^a,b   Martin, Marlena S ^a,b   Njar, Vincent C O ^a,b,c  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Chloroquine; Pharmacokinetics; RAMBAs; Toxicology; VN 12 1

Indexed keywords

ANTINEOPLASTIC AGENT; CHLOROQUINE; RETINOIC ACID; RETINOIC ACID METABOLISM BLOCKING AGENT; UNCLASSIFIED DRUG; VN 12 1; VN 2 1;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG MEGADOSE; DRUG STRUCTURE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LOW DRUG DOSE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; ANTINEOPLASTIC AGENTS; AUTOPHAGY; CHLOROQUINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; IMIDAZOLES; INJECTIONS, SUBCUTANEOUS; MICE; MICE, SCID; MOLECULAR STRUCTURE; TOXICITY TESTS; TRETINOIN;

EID: 84866535324     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-012-1877-z     Document Type: Article

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