메뉴 건너뛰기




Volumn 21, Issue 10, 2012, Pages 1463-1474

Insulin and GLP-1 analog combinations in type 2 diabetes mellitus: A critical review

Author keywords

Combination therapy; GLP 1; GLP 1 analog; Insulin; Type 2 diabetes mellitus

Indexed keywords

ALBIGLUTIDE; DULAGLUTIDE; EXENDIN 4; GLIMEPIRIDE; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; HEMOGLOBIN A1C; INSULIN; INSULIN ASPART; INSULIN DEGLUDEC; INSULIN DETEMIR; INSULIN GLARGINE; INSULIN GLULISINE; INSULIN LISPRO; ISOPHANE INSULIN; LIRAGLUTIDE; LIXISENATIDE; METFORMIN; PIOGLITAZONE; PLACEBO; RECOMBINANT HUMAN INSULIN; SEMIGLUTIDE; SHORT ACTING DRUG; SITAGLIPTIN; SULFONYLUREA DERIVATIVE; U 500; UNCLASSIFIED DRUG;

EID: 84866534106     PISSN: 13543784     EISSN: 17447658     Source Type: Journal    
DOI: 10.1517/13543784.2012.707190     Document Type: Review
Times cited : (16)

References (62)
  • 2
    • 0031972156 scopus 로고    scopus 로고
    • UKPDS 26: Sulphonylurea failure in non-insulin-dependent diabetic patients over six years. UK Prospective Diabetes Study (UKPDS) Group
    • Matthews DR, Cull CA, Stratton IM, et al. UKPDS 26: sulphonylurea failure in non-insulin-dependent diabetic patients over six years. UK Prospective Diabetes Study (UKPDS) Group. Diabet Med 1998;15:297-303
    • (1998) Diabet Med , vol.15 , pp. 297-303
    • Matthews, D.R.1    Cull, C.A.2    Stratton, I.M.3
  • 3
    • 0037283601 scopus 로고    scopus 로고
    • The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
    • Kahn SE. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes. Diabetologia 2003;46:3-19 (Pubitemid 36237741)
    • (2003) Diabetologia , vol.46 , Issue.1 , pp. 3-19
    • Kahn, S.E.1
  • 4
    • 19944390213 scopus 로고    scopus 로고
    • Pathogenesis of type 2 diabetes mellitus
    • DOI 10.1016/j.arcmed.2005.01.003, PII S0188440905000044, Current Trends in Diabetes
    • Leahy JL. Pathogenesis of type 2 diabetes mellitus. Arch Med Res 2005;36:197-209 (Pubitemid 40755133)
    • (2005) Archives of Medical Research , vol.36 , Issue.3 , pp. 197-209
    • Leahy, J.L.1
  • 5
    • 0942279564 scopus 로고    scopus 로고
    • Beta-cell dysfunction and glucose intolerance: Results from the San Antonio metabolism (SAM) study
    • DOI 10.1007/s00125-003-1263-9
    • Gastaldelli A, Ferrannini E, Miyazaki Y, et al. Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study. Diabetologia 2004;47:31-9 (Pubitemid 38141937)
    • (2004) Diabetologia , vol.47 , Issue.1 , pp. 31-39
    • Gastaldelli, A.1    Ferrannini, E.2    Miyazaki, Y.3    Matsuda, M.4    DeFronzo, R.A.5
  • 6
    • 79953032799 scopus 로고    scopus 로고
    • Long term patterns of use after initiation of oral antidiabetic drug therapy
    • Lamberts EJ, Nijpels G, Welschen LM, et al. Long term patterns of use after initiation of oral antidiabetic drug therapy. Pharmacoepidemiol Drug Saf 2011;20:351-8
    • (2011) Pharmacoepidemiol Drug Saf , vol.20 , pp. 351-358
    • Lamberts, E.J.1    Nijpels, G.2    Welschen, L.M.3
  • 7
    • 82655178563 scopus 로고    scopus 로고
    • Beyond metformin: Initiating combination therapy in patients with type 2 diabetes mellitus
    • Goldman-Levine JD. Beyond metformin: initiating combination therapy in patients with type 2 diabetes mellitus. Pharmacotherapy 2011;31:44S-53S
    • (2011) Pharmacotherapy , vol.31
    • Goldman-Levine, J.D.1
  • 8
    • 77954579761 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 analog and insulin combination therapy in the management of adults with type 2 diabetes mellitus
    • Tzefos M, Olin JL. Glucagon-like peptide-1 analog and insulin combination therapy in the management of adults with type 2 diabetes mellitus. Ann Pharmacother 2010;44:1294-300
    • (2010) Ann Pharmacother , vol.44 , pp. 1294-1300
    • Tzefos, M.1    Olin, J.L.2
  • 9
    • 80052067058 scopus 로고    scopus 로고
    • Combining basal insulin analogs with glucagon-like peptide-1 mimetics
    • Perfetti R. Combining basal insulin analogs with glucagon-like peptide-1 mimetics. Diabetes Technol Ther 2011;13:873-81
    • (2011) Diabetes Technol Ther , vol.13 , pp. 873-881
    • Perfetti, R.1
  • 10
    • 79551615182 scopus 로고    scopus 로고
    • Use of twice-daily exenatide in Basal insulin-treated patients with type 2 diabetes: A randomized, controlled trial
    • Buse JB, Bergenstal RM, Glass LC, et al. Use of twice-daily exenatide in Basal insulin-treated patients with type 2 diabetes: a randomized, controlled trial. Ann Intern Med 2011;154:103-12
    • (2011) Ann Intern Med , vol.154 , pp. 103-112
    • Buse, J.B.1    Bergenstal, R.M.2    Glass, L.C.3
  • 11
    • 33745970187 scopus 로고    scopus 로고
    • Exenatide: An incretin mimetic for the treatment of type 2 diabetes mellitus
    • DOI 10.1016/j.clinthera.2006.05.006, PII S0149291806001172
    • Iltz JL, Baker DE, Setter SM, Keith CR. Exenatide: an incretin mimetic for the treatment of type 2 diabetes mellitus. Clin Ther 2006;28:652-65 (Pubitemid 44067260)
    • (2006) Clinical Therapeutics , vol.28 , Issue.5 , pp. 652-665
    • Iltz, J.L.1    Baker, D.E.2    Setter, S.M.3    Keith Campbell, R.4
  • 12
    • 79955960213 scopus 로고    scopus 로고
    • DURATION-2: Efficacy and safety of switching from maximum daily sitagliptin or pioglitazone to once-weekly exenatide
    • Wysham C, Bergenstal R, Malloy J, et al. DURATION-2: efficacy and safety of switching from maximum daily sitagliptin or pioglitazone to once-weekly exenatide. Diabet Med 2011;28:705-14
    • (2011) Diabet Med , vol.28 , pp. 705-714
    • Wysham, C.1    Bergenstal, R.2    Malloy, J.3
  • 13
    • 79955661908 scopus 로고    scopus 로고
    • DURATION-5: Exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes
    • Blevins T, Pullman J, Malloy J, et al. DURATION-5: exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes. J Clin Endocrinol Metab 2011;96:1301-10
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 1301-1310
    • Blevins, T.1    Pullman, J.2    Malloy, J.3
  • 14
    • 77953859640 scopus 로고    scopus 로고
    • Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): An open-label randomised trial
    • Diamant M, Van GL, Stranks S, et al. Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomised trial. Lancet 2010;375:2234-43
    • (2010) Lancet , vol.375 , pp. 2234-2243
    • Diamant, M.1    Van Gl Stranks, S.2
  • 15
    • 77955573674 scopus 로고    scopus 로고
    • Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): A randomised trial
    • Bergenstal RM, Wysham C, MacConell L, et al. Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): a randomised trial. Lancet 2010;376:431-9
    • (2010) Lancet , vol.376 , pp. 431-439
    • Bergenstal, R.M.1    Wysham, C.2    MacConell, L.3
  • 16
    • 77953828230 scopus 로고    scopus 로고
    • DURATION-1: Exenatide once weekly produces sustained glycemic control and weight loss over 52 weeks
    • Buse JB, Drucker DJ, Taylor KL, et al. DURATION-1: exenatide once weekly produces sustained glycemic control and weight loss over 52 weeks. Diabetes Care 2010;33:1255-61
    • (2010) Diabetes Care , vol.33 , pp. 1255-1261
    • Buse, J.B.1    Drucker, D.J.2    Taylor, K.L.3
  • 17
    • 73349102524 scopus 로고    scopus 로고
    • The safety and efficacy of liraglutide with or without oral antidiabetic drug therapy in type 2 diabetes: An overview of the LEAD 1-5 studies
    • Blonde L, Russell-Jones D. The safety and efficacy of liraglutide with or without oral antidiabetic drug therapy in type 2 diabetes: an overview of the LEAD 1-5 studies. Diabetes Obes Metab 2009;11(Suppl 3):26-34
    • (2009) Diabetes Obes Metab , vol.11 , Issue.SUPPL. 3 , pp. 26-34
    • Blonde, L.1    Russell-Jones, D.2
  • 21
    • 84855185039 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2012
    • American Diabetes Association.
    • American Diabetes Association. Standards of medical care in diabetes-2012. Diabetes Care 2012;35:S11-63
    • (2012) Diabetes Care , vol.35
  • 22
    • 60449089649 scopus 로고    scopus 로고
    • Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes
    • Nathan DM, Buse JB, Davidson MB, et al. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009;32:193-203
    • (2009) Diabetes Care , vol.32 , pp. 193-203
    • Nathan, D.M.1    Buse, J.B.2    Davidson, M.B.3
  • 23
    • 14244264433 scopus 로고    scopus 로고
    • Pamphlet/product Eli Lilly and Co; Indianapolis, IN
    • Pamphlet/product. Byetta prescribing information. Eli Lilly and Co; Indianapolis, IN: 2011
    • (2011) Byetta Prescribing Information
  • 24
    • 26944477362 scopus 로고    scopus 로고
    • Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: A randomized trial
    • Heine RJ, Van Gaal LF, Johns D, et al. Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial. Ann Intern Med 2005;143:559-69
    • (2005) Ann Intern Med , vol.143 , pp. 559-569
    • Heine, R.J.1    Van Gaal, L.F.2    Johns, D.3
  • 25
    • 34247195226 scopus 로고    scopus 로고
    • A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: A non-inferiority study
    • Nauck MA, Duran S, Kim D, et al. A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: a non-inferiority study. Diabetologia 2007;50:259-67
    • (2007) Diabetologia , vol.50 , pp. 259-267
    • Nauck, M.A.1    Duran, S.2    Kim, D.3
  • 26
    • 84866537300 scopus 로고    scopus 로고
    • Pamphletproduct Novo-Nordisk; Princeton NJ
    • Pamphlet/product. Victoza prescribing information. Novo-Nordisk; Princeton, NJ: 2011
    • (2011) Victoza Prescribing Information
  • 27
    • 84893298120 scopus 로고    scopus 로고
    • Pamphletproduct Amylin Pharmaceuticals; San Diego CA
    • Pamphlet/product. Bydureon prescribing information. Amylin Pharmaceuticals; San Diego, CA: 2012
    • (2012) Bydureon Prescribing Information
  • 28
    • 67649666737 scopus 로고    scopus 로고
    • Liraglutide once a day versus exenatide twice a day for type 2 diabetes: A 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
    • Buse JB, Rosenstock J, Sesti G, et al. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6). Lancet 2009;374:39-47
    • (2009) Lancet , vol.374 , pp. 39-47
    • Buse, J.B.1    Rosenstock, J.2    Sesti, G.3
  • 29
    • 53249142132 scopus 로고    scopus 로고
    • Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: A randomised, open-label, non-inferiority study
    • Drucker DJ, Buse JB, Taylor K, et al. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study. Lancet 2008;372:1240-50
    • (2008) Lancet , vol.372 , pp. 1240-1250
    • Drucker, D.J.1    Buse, J.B.2    Taylor, K.3
  • 30
    • 80052645534 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 analogues for type 2 diabetes mellitus: Current and emerging agents
    • Gallwitz B. Glucagon-like peptide-1 analogues for type 2 diabetes mellitus: current and emerging agents. Drugs 2011;71:1675-88
    • (2011) Drugs , vol.71 , pp. 1675-1688
    • Gallwitz, B.1
  • 31
    • 36048966003 scopus 로고    scopus 로고
    • Exploring the substitution of exenatide for insulin in patients with type 2 diabetes treated with insulin in combination with oral antidiabetes agents
    • DOI 10.2337/dc06-2532
    • Davis SN, Johns D, Maggs D, et al. Exploring the substitution of exenatide for insulin in patients with type 2 diabetes treated with insulin in combination with oral antidiabetes agents. Diabetes Care 2007;30:2767-72 (Pubitemid 350083115)
    • (2007) Diabetes Care , vol.30 , Issue.11 , pp. 2767-2772
    • Davis, S.N.1    Johns, D.2    Maggs, D.3    Xu, H.4    Northrup, J.H.5    Brodows, R.G.6
  • 32
    • 48949098988 scopus 로고    scopus 로고
    • Safety and efficacy of exenatide in combination with insulin in patients with type 2 diabetes mellitus
    • Sheffield CA, Kane MP, Busch RS, et al. Safety and efficacy of exenatide in combination with insulin in patients with type 2 diabetes mellitus. Endocr Pract 2008;14:285-92
    • (2008) Endocr Pract , vol.14 , pp. 285-292
    • Sheffield, C.A.1    Kane, M.P.2    Busch, R.S.3
  • 33
    • 68649099986 scopus 로고    scopus 로고
    • Exenatide added to insulin therapy: A retrospective review of clinical practice over two years in an academic endocrinology outpatient setting
    • Yoon NM, Cavaghan MK, Brunelle RL, Roach P. Exenatide added to insulin therapy: a retrospective review of clinical practice over two years in an academic endocrinology outpatient setting. Clin Ther 2009;31:1511\23
    • (2009) Clin Ther , vol.31 , pp. 1511-1523
    • Yoon, N.M.1    Cavaghan, M.K.2    Brunelle, R.L.3    Roach, P.4
  • 34
    • 84858079439 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 (GLP-1) analogue combined with insulin reduces HbA1c and weight with low risk of hypoglycemia and high treatment satisfaction
    • Lind M, Jendle J, Torffvit O, Lager I. Glucagon-like peptide 1 (GLP-1) analogue combined with insulin reduces HbA1c and weight with low risk of hypoglycemia and high treatment satisfaction. Prim Care Diabetes 2012;6:41-6
    • (2012) Prim Care Diabetes , vol.6 , pp. 41-46
    • Lind, M.1    Jendle, J.2    Torffvit, O.3    Lager, I.4
  • 35
    • 84863607542 scopus 로고    scopus 로고
    • Addition of exenatide to insulin therapy in individuals with type 2 diabetes in UK routine clinical practice
    • Price HC, Gorst C, Ayyagari U, et al. Addition of exenatide to insulin therapy in individuals with type 2 diabetes in UK routine clinical practice. Pract Diabetes 2012;29:61-4
    • (2012) Pract Diabetes , vol.29 , pp. 61-64
    • Price, H.C.1    Gorst, C.2    Ayyagari, U.3
  • 36
    • 78449248761 scopus 로고    scopus 로고
    • The Association of British Clinical Diabetologists (ABCD) nationwide exenatide audit
    • Ryder R, Thong K, Cull M, et al. The Association of British Clinical Diabetologists (ABCD) nationwide exenatide audit. Pract Diab Int 2010;27:352-357b
    • (2010) Pract Diab Int , vol.27
    • Ryder, R.1    Thong, K.2    Cull, M.3
  • 37
    • 79959428521 scopus 로고    scopus 로고
    • Safety, efficacy and tolerability of exenatide in combination with insulin in the Association of British Clinical Diabetologists nationwide exenatide audit
    • Thong KY, Jose B, Sukumar N, et al. Safety, efficacy and tolerability of exenatide in combination with insulin in the Association of British Clinical Diabetologists nationwide exenatide audit. Diabetes Obes Metab 2011;13:703-10
    • (2011) Diabetes Obes Metab , vol.13 , pp. 703-710
    • Thong, K.Y.1    Jose, B.2    Sukumar, N.3
  • 38
    • 80051569955 scopus 로고    scopus 로고
    • Response at 3 months to insulin dose decisions made at exenatide initiation in the Association of British Clinical Diabetologists (ABCD) nationwide exenatide audit
    • Thong KY, Jose B, Blann AD, et al. Response at 3 months to insulin dose decisions made at exenatide initiation in the Association of British Clinical Diabetologists (ABCD) nationwide exenatide audit. Diabetes Res Clin Pract 2011;93:87-91
    • (2011) Diabetes Res Clin Pract , vol.93 , pp. 87-91
    • Thong, K.Y.1    Jose, B.2    Blann, A.D.3
  • 39
    • 77955262909 scopus 로고    scopus 로고
    • Further improvement in postprandial glucose control with addition of exenatide or sitagliptin to combination therapy with insulin glargine and metformin: A proof-of-concept study
    • Arnolds S, Dellweg S, Clair J, et al. Further improvement in postprandial glucose control with addition of exenatide or sitagliptin to combination therapy with insulin glargine and metformin: a proof-of-concept study. Diabetes Care 2010;33:1509-15
    • (2010) Diabetes Care , vol.33 , pp. 1509-1515
    • Arnolds, S.1    Dellweg, S.2    Clair, J.3
  • 41
    • 84866545755 scopus 로고    scopus 로고
    • Lixisenatide: Evidence for its potential use in the treatment of type 2 diabetes
    • Barnett AH. Lixisenatide: evidence for its potential use in the treatment of type 2 diabetes. Core Evid 2011;6:67-79
    • (2011) Core Evid , vol.6 , pp. 67-79
    • Barnett, A.H.1
  • 42
    • 33644817974 scopus 로고    scopus 로고
    • Hypoglycemia in type 2 diabetes: Pathophysiology, frequency, and effects of different treatment modalities
    • DOI 10.2337/diacare.28.12.2948
    • Zammitt NN, Frier BM. Hypoglycemia in type 2 diabetes: pathophysiology, frequency, and effects of different treatment modalities. Diabetes Care 2005;28:2948-61 (Pubitemid 43942931)
    • (2005) Diabetes Care , vol.28 , Issue.12 , pp. 2948-2961
    • Zammitt, N.N.1    Frier, B.M.2
  • 43
    • 18144388647 scopus 로고    scopus 로고
    • Defining and reporting hypoglycemia in diabetes
    • Workgroup on Hypoglycemia American Diabetes Association
    • Workgroup on Hypoglycemia, American Diabetes Association. Defining and reporting hypoglycemia in diabetes. Diabetes Care 2005;28:1245-9
    • (2005) Diabetes Care , vol.28 , pp. 1245-1249
  • 46
    • 77249148309 scopus 로고    scopus 로고
    • Glucose variability is associated with intensive care unit mortality
    • Hermanides J, Vriesendorp TM, Bosman RJ, et al. Glucose variability is associated with intensive care unit mortality. Crit Care Med 2010;38:838-42
    • (2010) Crit Care Med , vol.38 , pp. 838-842
    • Hermanides, J.1    Vriesendorp, T.M.2    Bosman, R.J.3
  • 48
    • 0036959991 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers
    • DOI 10.1210/jc.87.3.1239
    • Nauck MA, Heimesaat MM, Behle K, et al. Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers. J Clin Endocrinol Metab 2002;87:1239-46 (Pubitemid 36121094)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.3 , pp. 1239-1246
    • Nauck, M.A.1    Heimesaat, M.M.2    Behle, K.3    Holst, J.J.4    Nauck, M.S.5    Ritzel, R.6    Hufner, M.7    Schmiegel, W.H.8
  • 49
    • 0034819464 scopus 로고    scopus 로고
    • Combination therapies with insulin in type 2 diabetes
    • Yki-Jarvinen H. Combination therapies with insulin in type 2 diabetes. Diabetes Care 2001;24:758-67 (Pubitemid 32888861)
    • (2001) Diabetes Care , vol.24 , Issue.4 , pp. 758-767
    • Yki-Jarvinen, H.1
  • 50
    • 33746391488 scopus 로고    scopus 로고
    • A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-Naïve people with type 2 diabetes
    • DOI 10.2337/dc05-1365
    • Hermansen K, Davies M, Derezinski T, et al. A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naive people with type 2 diabetes. Diabetes Care 2006;29:1269-74 (Pubitemid 44125921)
    • (2006) Diabetes Care , vol.29 , Issue.6 , pp. 1269-1274
    • Hermansen, K.1    Davies, M.2    Derezinski, T.3    Ravn, G.M.4    Clauson, P.5    Home, P.6
  • 51
    • 39049105019 scopus 로고    scopus 로고
    • A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes
    • Rosenstock J, Davies M, Home PD, et al. A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes. Diabetologia 2008;51:408-16
    • (2008) Diabetologia , vol.51 , pp. 408-416
    • Rosenstock, J.1    Davies, M.2    Home, P.D.3
  • 52
    • 36448968168 scopus 로고    scopus 로고
    • Bodyweight changes associated with antihyperglycaemic agents in type 2 diabetes mellitus
    • Hermansen K, Mortensen LS. Bodyweight changes associated with antihyperglycaemic agents in type 2 diabetes mellitus. Drug Saf 2007;30:1127-42 (Pubitemid 350172854)
    • (2007) Drug Safety , vol.30 , Issue.12 , pp. 1127-1142
    • Hermansen, K.1    Mortensen, L.S.2
  • 54
    • 70450190143 scopus 로고    scopus 로고
    • Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue
    • Jendle J, Nauck MA, Matthews DR, et al. Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue. Diabetes Obes Metab 2009;11:1163-72
    • (2009) Diabetes Obes Metab , vol.11 , pp. 1163-1172
    • Jendle, J.1    Nauck, M.A.2    Matthews, D.R.3
  • 55
    • 77955915187 scopus 로고    scopus 로고
    • Exenatide therapy in insulin-treated type 2 diabetes and obesity
    • Nayak UA, Govindan J, Baskar V, et al. Exenatide therapy in insulin-treated type 2 diabetes and obesity. QJM 2010;103:687-94
    • (2010) QJM , vol.103 , pp. 687-694
    • Nayak, U.A.1    Govindan, J.2    Baskar, V.3
  • 56
    • 79955661908 scopus 로고    scopus 로고
    • DURATION-5: Exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes
    • Blevins T, Pullman J, Malloy J, et al. DURATION-5: exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes. J Clin Endocrinol Metab 2011;96:1301-10
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 1301-13010
    • Blevins, T.1    Pullman, J.2    Malloy, J.3
  • 57
    • 84857385645 scopus 로고    scopus 로고
    • Efficacy and safety of exenatide once weekly versus liraglutide in subjects with type 2 diabetes (DURATION-6): A randomised, open-label study
    • Buse JB, Nauck MA, Forst T, et al. Efficacy and safety of exenatide once weekly versus liraglutide in subjects with type 2 diabetes (DURATION-6): a randomised, open-label study. Diabetologia 2011;54(Suppl):OP13
    • (2011) Diabetologia , vol.54 , Issue.SUPPL.
    • Buse, J.B.1    Nauck, M.A.2    Forst, T.3
  • 58
    • 79959559653 scopus 로고    scopus 로고
    • Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
    • Elashoff M, Matveyenko AV, Gier B, et al. Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies. Gastroenterology 2011;141:150-6
    • (2011) Gastroenterology , vol.141 , pp. 150-156
    • Elashoff, M.1    Matveyenko, A.V.2    Gier, B.3
  • 59
    • 79951704452 scopus 로고    scopus 로고
    • Acute pancreatitis in type 2 diabetes treated with exenatide or sitagliptin: A retrospective observational pharmacy claims analysis
    • Garg R, Chen W, Pendergrass M. Acute pancreatitis in type 2 diabetes treated with exenatide or sitagliptin: a retrospective observational pharmacy claims analysis. Diabetes Care 2010;33:2349-54
    • (2010) Diabetes Care , vol.33 , pp. 2349-2354
    • Garg, R.1    Chen, W.2    Pendergrass, M.3
  • 60
    • 67649304917 scopus 로고    scopus 로고
    • Use of a claims-based active drug safety surveillance system to assess the risk of acute pancreatitis with exenatide or sitagliptin compared to metformin or glyburide
    • Dore DD, Seeger JD, Arnold CK. Use of a claims-based active drug safety surveillance system to assess the risk of acute pancreatitis with exenatide or sitagliptin compared to metformin or glyburide. Curr Med Res Opin 2009;25:1019-27
    • (2009) Curr Med Res Opin , vol.25 , pp. 1019-1027
    • Dore, D.D.1    Seeger, J.D.2    Arnold, C.K.3
  • 61
    • 79954994764 scopus 로고    scopus 로고
    • A cohort study of acute pancreatitis in relation to exenatide use
    • Dore DD, Bloomgren GL, Wenten M, et al. A cohort study of acute pancreatitis in relation to exenatide use. Diabetes Obes Metab 2011;13:559-66
    • (2011) Diabetes Obes Metab , vol.13 , pp. 559-566
    • Dore, D.D.1    Bloomgren, G.L.2    Wenten, M.3
  • 62
    • 84874439426 scopus 로고    scopus 로고
    • Zealand Pharma announces additional positive results for lixisenatide (Lyxumia® 1) Phase III Program in Type 2 Diabetes
    • [Last accessed 19 March 2012]
    • From the Global GetGoal Zealand Pharma Announces Additional Positive Results for Lixisenatide (Lyxumia® 1) from the Global GetGoal Phase III Program in Type 2 Diabetes. Zealand Pharma. 2012.Available From: Http://ir. Zealandpharma.com/releasedetail.cfm? ReleaseID=647087 [Last Accessed 19 March 2012]
    • (2012) Zealand Pharma


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.