Organizer and regulatory role of colonic isolated lymphoid follicles in inflammation

Acta Physiologica Hungarica

Volumn 99, Issue 3, 2012, Pages 344-352

  Constantinovits, M ^a   Sipos, F ^a   Molnar B ^b   Tulassay, Zs ^b   Muzes, Györgyi ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

bone marrow derived stem cells; colonic inflammation; epithelial repair; follicular dendritic cell; isolated lymphoid follicle; myofibroblast

Indexed keywords

5' NUCLEOTIDASE; B CELL ACTIVATING FACTOR; CD23 ANTIGEN; CD40 ANTIGEN; CELL ADHESION MOLECULE; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C3D RECEPTOR; DNA; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBRIN; FIBRINOGEN; HEAT SHOCK PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; RNA; SCLEROPROTEIN; TOLL LIKE RECEPTOR; TRANSFORMING GROWTH FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; BASEMENT MEMBRANE; BONE MARROW TRANSPLANTATION; CELL HOMING; COLITIS; FOLLICULAR DENDRITIC CELL; HEAT; ISOLATED LYMPHOID FOLLICLE; LIGAND BINDING; LYMPH FOLLICLE; LYMPHOCYTE MIGRATION; MYOFIBROBLAST; NEUTROPHIL; NONHUMAN; PEYER PATCH; STEM CELL; TISSUE NECROSIS; TRANSCELLULAR CELL MIGRATION; Y CHROMOSOME;

ANIMALS; COLITIS; COLON; DENDRITIC CELLS; FIBROBLASTS; HEMATOPOIETIC STEM CELLS; HUMANS; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; LYMPHOID TISSUE;

EID: 84866533625     PISSN: 0231424X     EISSN: 15882683     Source Type: Journal    
DOI: 10.1556/APhysiol.99.2012.3.11     Document Type: Article

References (61)

1. Andoh A, Bamba S, Fujiyama Y, Brittan M, Wright NA: Colonic subepithelial myofibroblasts in mucosal inflammation and repair: Contribution of bone marrow-derived stem cells to the gut regenerative response. J. Gastroenterol. 40, 1089-1099 (2005 (Pubitemid 43124835)
2. Azzali G: Structure, lymphatic vascularization and lymphocyte migration in mucosa-associated lymphoid tissue. Immunol. Rev. 195, 178-189 (2003 (Pubitemid 37153461)
3. Baird AW, Cuthbert AW: Neuronal involvement in type 1 hypersensitivity reactions in gut epithelia. Br. J. Pharmacol. 92, 647-655 (1987 (Pubitemid 17161067)
4. Beg AA: Endogenous ligands of Toll-like receptors: Implications for regulating inflammatory and immune responses. Trends. Immunol. 23, 509-512 (2002 (Pubitemid 35223541)
5. Cavender DE, Haskard DO, Joseph B, Ziff M: Interleukin 1 increases the binding of human B and T lymphocytes to endothelial cell monolayers. J. Immunol. 136, 203-207 (1986 (Pubitemid 16232174)
6. Cesta MF: Normal structure, function, and histology of mucosa-associated lymphoid tissue. Toxicologic Pathology 34, 599-608 (2006 (Pubitemid 44652219)
7. Chamberlain G, Fox J, Ashton B, Middleton J: Concise review: Mesenchymal stem cells: Their phenotype, differentiation capacity, immunological features, and potential for homing. Stem Cells 25, 2739-2749 (2007 (Pubitemid 350127858)
8. Chiocchetti R, Mazzuoli G, Albanese V, Mazzoni M, Clavenzani P, Lalatta-Costerbosa G, Lucchi ML, Di Guardo G, Marruchella G, Furness JB: Anatomical evidence for ileal Peyer's patches innervation by enteric nervous system: A potential route for prion neuroinvasion? Cell Tissue Res. 332, 185-194 (2008
9. Chugh AR, Zuba-Surma EK, Dawn B: Bone marrow-derived mesenchymal stems cells and cardiac repair. Minerva Cardioangiol. 57, 185-202 (2009
10. Freemont AJ, Ford WL: Functional and morphological changes in post-capillary venules in relation to lymphocytic infiltration into BCG-induced granulomata in rat skin. J. Pathol. 147, 1-12 (1985 (Pubitemid 15020127)
11. Gormley PD, Powell-Richards AO, Azuara-Blanco A, Donoso LA, Dua HS: Lymphocyte subsets in conjunctival mucosa-associated lymphoid-tissue after exposure to retinal-S-antigen. Int. Ophthalmol. 22, 77-80 (1998 (Pubitemid 29396300)
12. Guo L, Kuroda N, Nakayama H, Miyazaki E, Hayashi Y, Toi M, Hiroi M, Enzan H: Cytokeratin-positive subserosal myofibroblasts in gastroduodenal ulcer; another type of myofibroblasts. Histol. Histopathol. 21, 697-704 (2006 (Pubitemid 44082711)
13. Hamauzu T, Kuroda N, Guo L, Miyazaki E, Hayashi Y, Toi M, Hiroi M, Enzan H: CAM5.2-positive subserosal myofibroblasts in appendicitis. Med. Mol. Morphol. 39, 209-213 (2006 (Pubitemid 46013060)
14. Hirose J, Kawashima H, Yoshie O, Tashiro K, Miyasaka M: Versican interacts with chemokines and modulates cellular responses. J. Biol. Chem. 276, 5228-5234 (2001
15. Humphrey JH, Grennan D, Sundaram V: The origin of follicular dendritic cells in the mouse and the mechanism of trapping of immune complexes on them. Eur. J. Immunol. 14, 859-864 (1994
16. Jakubzick C, Bogunovic M, Bonito AJ, Kuan EL, Merad M, Randolph GJ: Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes. J. Exp. Med. 205, 2839-2850 (2008
17. Joyce NC, Haire MF, Palade GE: Morphologic and biochemical evidence for a contractile cell network within the rat intestinal mucosa. Gastroenterology 92, 68-81 (1987 (Pubitemid 17207663)
18. Kapasi ZF, Qin D, Kerr WG, Kosco-Vilbois MH, Shultz LD, Tew JG, Szakal AK: Follicular dendritic cell (FDC) precursors in primary lymphoid tissues. J. Immunol. 160, 1078-1084 (1998 (Pubitemid 28093400)
19. Kim YS, Park HJ, Hong MH, Kang PM, Morgan JP, Jeong MH, Cho JG, Park JC, Ahn Y: TNF-alpha enhances engraftment of mesenchymal stem cells into infarcted myocardium. Front. Biosci. 14, 2845-2856 (2009
20. Kraehenbuhl J-P, Neutra MN: Molecular and cellular basis of immune protection of mucosal surfaces. Physiol. Rev. 72, 853-879 (1992
21. Kvietys PR, Sandig M: Neutrophil diapedesis: Paracellular or transcellular? News Physiol. Sci. 16, 15-19 (2001 (Pubitemid 33574451)
22. Le Visage C, Dunham B, Flint P, Leong KW: Coculture of mesenchymal stem cells and respiratory epithelial cells to engineer a human composite respiratory mucosa. Tissue Eng. 10, 1426-1435 (2004 (Pubitemid 39557846)
23. Li M, Carpio D, Zheng Y, Bruzzo P, Singh V, Ouaaz F, Medzhitov RM, Beg AA: An essential role of the NFkappa B/toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells. J. Immunol. 166, 7128-7135 (2001 (Pubitemid 32525583)
24. Lindhout E, Koopman G, Pals ST, de Groot C: Triple check for antigen specificity of B cells during germinal centre reactions. Immunol. Today 18, 573-577 (1997 (Pubitemid 28010968)
25. Liu N, Chen R, Du H, Wang J, Zhang Y, Wen J: Expression of IL-10 and TNF-alpha in rats with cerebral infarction after transplantation with mesenchymal stem cells. Cell. Mol. Immunol. 6, 207-213 (2009
26. Liu ZJ, Zhuge Y, Velazquez OC: Trafficking and differentiation of mesenchymal stem cells. J. Cell. Biochem. 106, 984-991 (2009
27. Lorenz RG, Chaplin DD, McDonald KG, McDonough JS, Newberry RD: Isolated lymphoid follicle formation is inducible and dependent upon lymphotoxin- sufficient B lymphocytes, lymphotoxin beta receptor, and TNF receptor I function. J. Immunol. 170, 5475-5482 (2003 (Pubitemid 36617835)
28. Majors A, Austin R, de la Motte C, Pyeritz RE, Hascall VC, Kessler SP, Sen G, Strong SA: Endoplasmic reticulum stress induces hyaluronan deposition and leukocyte adhesion. J. Biol. Chem. 278, 47223-47231 (2003 (Pubitemid 37452309)
29. Matsumoto T, Okamoto R, Yajima T, Mori T, Okamoto S, Ikeda Y, Mukai M, Yamazaki M, Oshima S, Tsuchiya K, Nakamura T, Kanai T, Okano H, Inazawa J, Hibi T, Watanabe M: Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine. Gastroenterology 128, 1851-1867 (2005 (Pubitemid 40824697)
30. McGhee JR, Mestecky J, Dertzbaugh MT, Eldridge JH, Hirasawa M, Kiyono H: The mucosal immune system: From fundamental concepts to vaccine development. Vaccine 10, 75-88 (1992
31. Moghaddami M, Cummins A, Mayrhofer G: Lymphocyte-filled villi: Comparison with other lymphoid aggregations in the mucosa of the human small intestine. Gastroenterology 115, 1414-1425 (1998 (Pubitemid 28545992)
32. Muñoz-Fernández R, Blanco FJ, Frecha C, Martín F, Kimatrai M, Abadía-Molina AC, García-Pacheco JM, Olivares EG: Follicular dendritic cells are related to bone marrow stromal cell progenitors and to myofibroblasts. J. Immunol. 177, 280-289 (2006 (Pubitemid 43939139)
33. Nascimbeni R, Di Fabio F, Di Betta E, Mariani P, Fisogni S, Villanacci V: Morphology of colorectal lymphoid aggregates in cancer, diverticular and inflammatory bowel diseases. Mod. Pathol. 18, 681-685 (2005 (Pubitemid 40676380)
34. Neutra MR, Frey A, Kraehenbuhl JP: Epithelial M cells: gateways for mucosal infection and immunization. Cell 86, 345-348 (1996 (Pubitemid 26272074)
35. Neutra MR, Mantis NJ, Kraehenbuhl JP: Collaboration of epithelial cells with organized mucosal lymphoid tissues. Nat. Immunol. 2, 1004-1009 (2001 (Pubitemid 33069494)
36. Niedergang F, Kraehenbuhl JP: Much ado about M cells. Trends Cell. Biol. 10, 137-141 (2000 (Pubitemid 30171307)
37. O'Brien LM, Fitzpatrick E, Baird AW, Campion DP: Eosinophil-nerve interactions and neuronal plasticity in rat gut associated lymphoid tissue (GALT) in response to enteric parasitism. J. Neuroimmunol. 197, 1-9 (2008
38. O'Malley KE, Sloan T, Joyce P, Baird AW: Type I hypersensitivity reactions in intestinal mucosae from rats infected with Fasciola hepatica. Parasite Immunol. 15, 449-453 (1993 (Pubitemid 23248597)
39. Onishi S, Miyata H, Inamoto T, Qi WM, Yamamoto K, Yokoyama T, Warita K, Hoshi N, Kitagawa H: Immunohistochemical study on the delayed progression of epithelial apoptosis in follicle-associated epithelium of rat Peyer's patch. J. Vet. Med. Sci. 69, 1123-1129 (2007 (Pubitemid 350248692)
40. Perry ME, Mustafa Y, Brown KA: The microvasculature of the human palatine tonsil and its role in the homing of lymphocytes. Adv. Otorhinolaryngol. 47, 11-15 (1992
41. Podolsky DK: Healing the epithelium: Solving the problem from two sides. J. Gastroenterol. 32, 122-126 (1997 (Pubitemid 27075894)
42. Powell DW, Adegboyega PA, Di Mari JF, Mifflin RC: Epithelial cells and their neighbors I. Role of intestinal myofibroblasts in development, repair, and cancer. Am. J. Physiol. Gastrointest. Liver. Physiol. 289, 2-7 (2005
43. Powell DW, Mifflin RC, Valentich JD, Crowe SE, Saada JI, West AB: Myofibroblasts. II. Intestinal subepithelial myofibroblasts. Am. J. Physiol. 277, C183-C201 (1999
44. Prindull G, Zipori D: Environmental guidance of normal and tumor cell plasticity: Epithelial mesenchymal transitions as a paradigm. Blood 103, 2892-2899 (2004 (Pubitemid 38451657)
45. Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R: Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118, 229-241 (2004 (Pubitemid 38962578)
46. Renes IB, Verburg M, Bulsing NP, Ferdinandusse S, Büller HA, Dekker J, Einerhand AW: Protection of the Peyer's patch-associated crypt and villus epithelium against methotrexate-induced damage is based on its distinct regulation of proliferation. J. Pathol. 198, 60-68 (2002 (Pubitemid 34966208)
47. Saxena SK, Thompson JS, Sharp JG: Role of organized intestinal lymphoid aggregates in intestinal regeneration. J. Invest. Surg. 10, 97-103 (1997 (Pubitemid 27296669)
48. Sheng W, Wang G, La Pierre DP, Wen J, Deng Z, Wong CK, Lee DY, Yang BB: Versican mediates mesenchymalepithelial transition. Mol. Biol. Cell. 17, 2009-2020 (2006
49. Sipos F, Muzes G, Valcz G, Galamb O, Tóth K, Leiszter K, Krenács T, Tulassay Z, Molnár B: Regeneration associated growth factor receptor and epithelial marker expression in lymphoid aggregates of ulcerative colitis. Scand. J. Gastroenterol. 45, 440-448 (2010
50. Sipos F, Muzes G, Galamb O, Spisák S, Krenács T, Tóth K, Tulassay Z, Molnár B: The possible role of isolated lymphoid follicles in colonic mucosal repair. Pathol. Onc. Res. 1, 11-18 (2010
51. Spees JL, Olson SD, Ylostalo J, Lynch PJ, Smith J, Perry A, Peister A, Wang MY, Prockop DJ: Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma. Proc. Natl Acad. Sci. USA 100, 2397-2402 (2003 (Pubitemid 36297510)
52. Stenson WF: Toll-like receptors and intestinal epithelial repair. Curr. Opin. Gastroenterol. 24, 103-107 (2008 (Pubitemid 351322773)
53. Thiery JP: Epithelial-mesenchymal transitions in development and pathologies. Curr. Opin. Cell. Biol. 15, 740-746 (2003 (Pubitemid 37487967)
54. Valcz G, Krenacs T, Sipos F, Patai AV, Wichmann B, Leiszter K, Toth K, Balogh Z, Csizmadia A, Hagymasi K, Masszi T, Molnar B, Tulassay Z: Lymphoid aggregates may contribute to the migration and epithelial commitment of bone marrow-derived cells in colonic mucosa. J. Clin. Pathol. 64, 771-775 (2011
55. Valcz G, Krenács T, Sipos F, Wichmann B, Tóth K, Leiszter K, Balogh Z, Csizmadia A, Hagymási K, Muzes G, Masszi T, Molnár B, Tulassay Z: A csontveli eredet ssejtek megjelenése az ép vastagbélhámban és a gyulladást követ hámregenerációban [Appearing of bone marrow derived stem cells in healthy and regenerating colonic epithelium]. Orv. Hetil. 40, 1852-1857 (2009
56. van Nierop K, de Groot C: Human follicular dendritic cells: Function, origin and development. Semin. Immunol. 14, 251-257 (2002 (Pubitemid 34969893)
57. Velázquez P, Wei B, Braun J: Surveillance B lymphocytes and mucosal immunoregulation. Springer. Semin. Immunopathol. 26, 453-462 (2005 (Pubitemid 40468896)
58. Vulchanova L, Casey MA, Crabb GW, Kennedy WR, Brown DR: Anatomical evidence for enteric neuroimmune interactions in Peyer's patches. J. Neuroimmunol. 185, 64-74 (2007 (Pubitemid 46497442)
59. Wallace JL, Granger DN: The cellular and molecular basis of gastric mucosal defense. FASEB. J. 10, 731-740 (1996 (Pubitemid 26172819)
60. Wei B, Velazquez P, Turovskaya O, Spricher K, Aranda R, Kronenberg M, Birnbaumer L, Braun J: Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets. Proc. Natl Acad. Sci. USA. 102, 2010-2015 (2005 (Pubitemid 40262003)
61. Yan Z, Wang JB, Gong S, Huang X: Cell proliferation in the endolymphatic sac in situ after the rat Waldeyer ring equivalent immunostimulation. Laryngoscope 113, 1609-1614 (1993