With sepsis: If fever is good, then hypothermia is bad!

Critical Care Medicine

Volumn 40, Issue 10, 2012, Pages 2926-

  Cunha, Burke A ^a,b  

^a WINTHROP UNIVERSITY HOSPITAL   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN; SUPEROXIDE;

ANTIBIOTIC SENSITIVITY; ANTIBODY PRODUCTION; BACTERIAL VIRULENCE; BIOLOGICAL ACTIVITY; BRAIN INJURY; CELL MIGRATION; CHEMOTAXIS; COMPLEMENT ACTIVATION; COMPLEMENT CLASSICAL PATHWAY; FEVER; HOST RESISTANCE; HUMAN; HYPERPYREXIA; HYPOTHERMIA; LETTER; LYMPHOCYTE PROLIFERATION; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SYNTHESIS; SEPSIS; SPIROCHETE; SURVIVAL RATE; SYPHILIS; T LYMPHOCYTE;

ANIMALS; DIAPHRAGM; FEMALE; MUSCLE WEAKNESS; NF-KAPPA B; VENTILATORS, MECHANICAL;

EID: 84866528730     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31825f78aa     Document Type: Letter

References (5)

1. Crouser ED: Warming up to hypothermia for treatment of severe sepsis. Crit Care Med 2012; 40:1020-1022
2. Roberts NJ Jr: Temperature and host defense. Microbiol Rev 1979; 43:241-259 (Pubitemid 9231878)
3. Kluger MJ, Kozak W, Conn CA, et al: The adaptive value of fever. Infect Dis Clin North Am 1996; 10:1-20 (Pubitemid 26105856)
4. Cunha BA: Fever myths and misconceptions: The benefcial effects of fever as a critical component of host defenses against infection. Heart Lung 2012; 41:99-101; author reply 99
5. Laupland KB, Zahar JR, Adrie C, et al: Severe hypothermia increases the risk for intensive care unit-acquired infection. Clin Infect Dis 2012; 54:1064-1070