Isolation and biochemical, functional and structural characterization of a novel l-amino acid oxidase from Lachesis muta snake venom

Toxicon

Volumn 60, Issue 7, 2012, Pages 1263-1276

  Bregge Silva, Cristiane ^a   Nonato, Maria Cristina ^a   de Albuquerque, Sérgio ^a   Ho, Paulo Lee ^b   Junqueira de Azevedo, Inácio L M ^b   Vasconcelos Diniz, Marcelo Ribeiro ^c   Lomonte, Bruno ^d   Rucavado, Alexandra ^d   Díaz, Cecilia ^d   Gutiérrez, José María ^d   Arantes, Eliane Candiani ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

^c FUNDAÇÃO EZEQUIEL DIAS   (Brazil)

^d UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

Cytotoxic activity; Enzyme structure; L amino acid oxidase; Lachesis muta; LmLAAO; Myotoxicity; SvLAAO

Indexed keywords

AMINO ACID; AMINO ACID OXIDASE; COMPLEMENTARY DNA; LACHESIS MUTA VENOM AMINO ACID OXIDASE; SNAKE VENOM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPARASITIC ACTIVITY; ARTICLE; CATALYSIS; CELL LINE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ISOLATION; ENZYME PURIFICATION; ENZYME STRUCTURE; EXPRESSED SEQUENCE TAG; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LACHESIS MUTA; LEISHMANIA BRAZILIENSIS; MASS SPECTROMETRY; MOLECULAR WEIGHT; MOUSE; MUSCLE NECROSIS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PREDICTION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SNAKE; STOMACH ADENOCARCINOMA; TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CROTALID VENOMS; HUMANS; L-AMINO ACID OXIDASE; LEISHMANIA BRAZILIENSIS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA;

LACHESIS MUTA; LEISHMANIA BRAZILIENSIS; MUS; TRYPANOSOMA CRUZI;

EID: 84866512570     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2012.08.008     Document Type: Article

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