Statins and cerebral perfusion in patients with leukoaraiosis - a translational proof-of-principal MRI study

International Journal of Stroke

Volumn 7, Issue 7, 2012, Pages

  Ebinger, Martin ^a,b   Brunecker, Peter ^a   Schultze Amberger, Jörg ^c   Gertz, Karen ^b   Müller, Bianca ^b   Fiebach, Jochen B ^a   Dichgans, Martin ^d   Endres, Matthias ^a,b  

^a Center for Stroke Research Berlin CSB   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c KLINIKUM ERNST VON BERGMANN   (Germany)

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; SIMVASTATIN;

ADULT; BRAIN BLOOD FLOW; BRAIN PERFUSION; CADASIL; CLINICAL ARTICLE; DRUG EFFECT; FEMALE; HUMAN; LETTER; LEUKOARAIOSIS; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

AGED; BRAIN; CEREBROVASCULAR CIRCULATION; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LEUKOARAIOSIS; MALE; MIDDLE AGED; TRANSLATIONAL MEDICAL RESEARCH;

EID: 84866509427     PISSN: 17474930     EISSN: 17474949     Source Type: Journal    
DOI: 10.1111/j.1747-4949.2012.00807.x     Document Type: Letter

References (5)

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2. Yamada M, Huang Z, Dalkara T etal. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab 2000; 20:709-717.
3. Sterzer P, Meintzschel F, Rosler A, Lanfermann H, Steinmetz H, Sitzer M. Pravastatin improves cerebral vasomotor reactivity in patients with subcortical small-vessel disease. Stroke 2001; 32:2817-2820.
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5. Brunecker P, Endres M, Nolte CH etal. Evluation of an AIF correction algorithm for dynamic susceptibility contrast-enhanced perfusion MRI. Magn Reson Med 2008; 60:102-110.