Transcriptional regulation and increased production of asukamycin in engineered Streptomyces nodosus subsp. asukaensis strains

Applied Microbiology and Biotechnology

Volumn 96, Issue 2, 2012, Pages 451-460

  Xie, Pengfei ^a   Sheng, Yan ^a   Ito, Takuya ^b   Mahmud, Taifo ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Asukamycin; Biosynthesis; Genetic engineering; Transcriptional regulation

Indexed keywords

ANTI-FUNGAL; ANTINEOPLASTIC ACTIVITY; ASUKAMYCIN; BIOSYNTHETIC GENE; BIOSYNTHETIC GENE CLUSTER; GENE DUPLICATIONS; GENE INACTIVATION; GENE PRODUCTS; IN-VIVO; MUTANT STRAIN; OVER-EXPRESSION; REGULATORY GENES; TRANSCRIPTIONAL ANALYSIS; TRANSCRIPTIONAL REGULATION; TRANSCRIPTIONAL REGULATOR; WILD-TYPE STRAIN;

ANTIBIOTICS; BACTERIA; BIOCHEMISTRY; BIOSYNTHESIS; GENETIC ENGINEERING;

GENES;

ASUKAMYCIN;

ANTIBIOTICS; ANTIMICROBIAL ACTIVITY; BACTERIUM; BIOLOGICAL PRODUCTION; GENE EXPRESSION; GENETIC ENGINEERING; MORPHOLOGY; MUTATION; PROTEIN;

ARTICLE; BACTERIAL STRAIN; BIOSYNTHESIS; GENE CASSETTE; GENE CLUSTER; GENE DUPLICATION; GENE IDENTIFICATION; GENE INACTIVATION; GENE OVEREXPRESSION; GENE PRODUCT; GENETIC ANALYSIS; IN VIVO STUDY; NONHUMAN; PROTEIN FUNCTION; STREPTOMYCES; STREPTOMYCES NODOSUS; TRANSCRIPTION REGULATION;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC ENGINEERING; MULTIGENE FAMILY; POLYENES; POLYUNSATURATED ALKAMIDES; STREPTOMYCES; TRANSCRIPTION, GENETIC; UP-REGULATION;

STREPTOMYCES NODOSUS SUBSP. ASUKAENSIS;

EID: 84866506780     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4084-2     Document Type: Article

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