The incidence and consequences of early wound infection after internal fixation for trauma in HIV-positive patients

Journal of Bone and Joint Surgery - Series B

Volumn 94 B, Issue 9, 2012, Pages 1265-1270

  Bates, J ^a   Mkandawire, N ^a   Harrison, W J ^a,b  

^a UNIVERSITY OF MALAWI   (Malawi)

^b College of Medicine ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BONE INJURY; CD4 LYMPHOCYTE COUNT; CHRONIC OSTEOMYELITIS; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; INFECTION RATE; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; OPEN FRACTURE; OSTEOSYNTHESIS; PATIENT SAFETY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SINGLE BLIND PROCEDURE; SURGICAL INFECTION; WOUND HEALING;

ADULT; AGED; AIDS-RELATED OPPORTUNISTIC INFECTIONS; CAUSALITY; CAUSE OF DEATH; COMORBIDITY; FEMALE; FRACTURE FIXATION, INTERNAL; FRACTURES, BONE; FRACTURES, UNUNITED; HIV SEROPOSITIVITY; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SINGLE-BLIND METHOD; SURGICAL WOUND INFECTION;

EID: 84866498693     PISSN: 0301620X     EISSN: None     Source Type: Journal    
DOI: 10.1302/0301-620X.94B9.28682     Document Type: Article

References (20)

1. Hoekman P, van de Perre P, Nelissen J, et al. Increased frequency of infection after open reduction of fractures in patients who are seropositive for human immunodeficiency virus. J Bone Joint Surg [Am] 1991;73-A:675-679.
2. Paiement GD, Hymes RA, LaDouceur MS, Gosselin RA, Green HD. Postoperative infections in asymptomatic HIV-seropositive orthopedic trauma patients. J Trauma 1994;37:545-550.
3. Cairns J. Surgery in high-HIV incidence poor countries. Trop Doct 2000;30:37-39.
4. Bahebeck J, Eone DH, Nonga BN, Kingue TN, Sosso M. Implant orthopaedic surgery in HIV asymptomatic carriers: management and early outcome. Injury 2009;40:1147-1150.
5. Aird J, Noor S, Lavy C, Rollinson P. The effect of HIV on early wound healing in open fractures treated with internal and external fixation. J Bone Joint Surg [Br] 2011;93-B:678-683.
6. Harrison WJ, Lewis CP, Lavy CB. Wound healing after implant surgery in HIV-positive patients. J Bone Joint Surg [Br] 2002;84-B:802-806.
7. No authors listed. British Association of Plastic, Reconstructive and Aesthetic Surgeons. Standards for the management of open fractures of the lower limb. http://www.bapras.org.uk/downloaddoc.asp?id=141 (date last accessed 22 May 2012).
8. No authors listed. UNGASS Country Progress Report (2010): Malawi HIV and AIDS Monitoring and Evaluation Report: 2008-2009. http://data.unaids.org/pub/ Report/2010/ malawi-2010-country-progress-report-en.pdf (date last accessed 16 July 2012).
9. Wilson AP, Treasure T, Sturridge MF, Grüneberg RN. A scoring method (ASEPSIS) for postoperative wound infections for use in clinical trials of antibiotic prophylaxis. Lancet 1986;1:311-313.
10. Ashby E, Haddad FS, O'Donnell E, Wilson AP. How will surgical site infection be measured to ensure "high quality care for all"? J Bone Joint Surg [Br] 2010;92-B:1294-1299.
11. Gustilo RB, Mendoza RM, Williams DN. Problems in the management of type 3 (severe) open fractures: a new classification of type 3 open fractures. J Trauma 1984;24:742-746.
12. Jellis JE. Orthopaedic surgery and HIV disease in Africa. Int Orthop 1996;20:253-256.
13. Savioz D, Chilcott M, Ludwig C, et al. Preoperative counts of CD4 T-lymphocytes and early postoperative infective complications in HIV-positive patients. Eur J Surg 1998;164:483-487.
14. Harrison WJ, Lewis CP, Lavy CB. Open fractures of the tibia in HIV positive patients: a prospective controlled single-blind study. Injury 2004;35:852-856.
15. Giannoudis P, Papakostidis C, Roberts C. A review of the management of open fractures of the tibia and femur. J Bone Joint Surg [Br] 2006;88-B:281-289.
16. Abalo A, Patassi A, James YE, et al. Risk factors for surgical wound infection in HIV-positive patients undergoing surgery for orthopaedic trauma. J Orthop Surg (Hong Kong) 2010;18:224-227.
17. Govender S, Harrison WJ, Lukhele M. Impact of HIV on bone and joint surgery. Best Pract Res Clin Rheumatol 2008;22:605-619.
18. No authors listed. Ministry of Health, Malawi. Treatment of AIDS: Guidelines for the use of Antiretroviral Therapy in Malawi. http://www.basics. org/documents/ ART-Guidelines-Malawi.pdf (date last accessed 22 May 2012).
19. No authors listed. World Health Organisation: Antiretroviral therapy for HIV infection in adults and adolescents: recommendations for a public health approach. http://www.who.int/hiv/pub/guidelines/artadultguidelines.pdf (date last accessed 22 May 2012).
20. Hunt PW, Deeks SG, Rodriguez B, et al. Continued CD4 cell count increases in HIV-infected adults experiencing 4 years of viral suppression on antiretroviral therapy. AIDS 2003;17:1907-1915.