On the influence of overexpression of phosphoenolpyruvate carboxykinase in Streptomyces lividans on growth and production of human tumour necrosis factor-alpha

Applied Microbiology and Biotechnology

Volumn 96, Issue 2, 2012, Pages 367-372

  Lule, Ivan ^a   Maldonado, Bárbara ^a,b   D'Huys, Pieter Jan ^a   Van Mellaert, Lieve ^a   Van Impe, Jan ^a   Bernaerts, Kristel ^a   Anné, Jozef ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b Cardiovascular Sciences   (Belgium)

Author keywords

Heterologous proteins; Human tumour necrosis factor alpha (hTNF a); Phosphoenolpyruvate carboxykinase (PEPCK); Streptomyces lividans

Indexed keywords

CONTROL STRAIN; EXPRESSION SYSTEM; GROWTH MEDIUM; HETEROLOGOUS PROTEIN PRODUCTION; HETEROLOGOUS PROTEINS; HUMAN TUMOUR NECROSIS FACTOR-ALPHA (HTNF-A); METABOLIC ENGINEERING APPROACH; OVER-EXPRESSION; PHOSPHOENOLPYRUVATE CARBOXYKINASE; PYRUVATES; STREPTOMYCES LIVIDANS;

GENE ENCODING; GLYCOPROTEINS; MACROPHAGES; STRAIN;

PROTEINS;

PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PYRUVIC ACID; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA;

ALKALINIZATION; BACTERIUM; BIOENGINEERING; BIOLOGICAL PRODUCTION; ENZYME ACTIVITY; FERMENTATION; GENE EXPRESSION; GROWTH; METABOLISM; PROTEIN; RECOMBINATION; TUMOR;

ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; ENZYME ACTIVITY; GENE OVEREXPRESSION; NONHUMAN; PHOSPHOENOLPYRUVATE CARBOXYKINASE GENE; STREPTOMYCES LIVIDANS;

BACTERIAL PROTEINS; GENE EXPRESSION; HUMANS; METABOLIC ENGINEERING; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); STREPTOMYCES COELICOLOR; STREPTOMYCES LIVIDANS; TUMOR NECROSIS FACTOR-ALPHA;

STREPTOMYCES LIVIDANS;

EID: 84866493378     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4182-1     Document Type: Article

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