Accurate variant detection across non-amplified and whole genome amplified DNA using targeted next generation sequencing

BMC Genomics

Volumn 13, Issue 1, 2012, Pages

  ElSharawy, Abdou ^a   Warner, Jason ^b   Olson, Jeff ^b   Forster, Michael ^a   Schilhabel, Markus B ^a   Link, Darren R ^b   Rose John, Stefan ^a   Schreiber, Stefan ^a,c   Rosenstiel, Philip ^a   Brayer, James ^b   Franke, Andre ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b RainDance Technologies Inc   (United States)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

Cost reduction; High throughput targeted next generation resequencing; Microdroplet based multiplex PCR; Sample pooling or multiplexing; Whole genome amplified DNA samples

Indexed keywords

GENOMIC DNA;

ARTICLE; DNA SEQUENCE; GENE AMPLIFICATION; GENE FREQUENCY; GENE TECHNOLOGY; GENETIC VARIABILITY; GENOTYPE; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN GENOME; INHERITANCE; PREDICTION; SEQUENCE ANALYSIS;

ALLELES; DATABASES, GENETIC; EXONS; GENE FREQUENCY; GENES, NEOPLASM; GENOME, HUMAN; GENOTYPE; HAPMAP PROJECT; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INHERITANCE PATTERNS; MULTIPLEX POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA;

EID: 84866489432     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-13-500     Document Type: Article

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