Effects of increased dietary cholesterol with carbohydrate restriction on hepatic lipid metabolism in guinea pigs

Comparative Medicine

Volumn 62, Issue 2, 2012, Pages 109-115

  DeOgburn, Ryan ^a   Leite, Jose O ^a,b   Ratliff, Joseph ^a   Volek, Jeff S ^a   McGrane, Mary M ^a   Fernandez, Maria Luz ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b UNIVERSIDADE JOSÉ DO ROSÁRIO VELLANO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; CHOLESTEROL; FATTY ACID; GLUCOSE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; BIOLOGICAL MARKER; ENZYME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CARBOHYDRATE DIET; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL INTAKE; CHOLESTEROL LIVER LEVEL; CONTROLLED STUDY; FATTY ACID BLOOD LEVEL; FATTY LIVER; GLUCOSE BLOOD LEVEL; GUINEA PIG; HYPERCHOLESTEROLEMIA; LIPID LIVER LEVEL; LIPID METABOLISM; LIVER CELL; LIVER METABOLISM; LIVER WEIGHT; LOW CARBOHYDRATE DIET; MALE; NONHUMAN; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; BLOOD; CALORIC INTAKE; CELL PROLIFERATION; DIET THERAPY; DISEASE MODEL; EATING; HOSPITALIZATION; LIVER; METABOLISM; ORGAN SIZE; PATHOLOGY; TIME;

ANIMALS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BODY WEIGHT; CELL PROLIFERATION; CHOLESTEROL, DIETARY; CHOLESTEROL, LDL; DIET, CARBOHYDRATE-RESTRICTED; DISEASE MODELS, ANIMAL; EATING; ENERGY INTAKE; ENZYMES; FATTY ACIDS, NONESTERIFIED; FATTY LIVER; GUINEA PIGS; HYPERCHOLESTEROLEMIA; LIVER; MALE; ORGAN SIZE; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TRIGLYCERIDES;

EID: 84866464071     PISSN: 15320820     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Accurso A, Bernstein RK, Dahlqvist A, Draznin B, Feinman RD, Fine EJ, Gleed A, Jacobs DB, Larson G, Lustig RH, Manninen AH, McFarlane SI, Morrison K, Nielsen JV, Ravnskov U, Roth KS, Silvestre R, Sowers JR, Sundberg R, Volek JS, Westman EC, Wood RJ, Wortman J, Vernon MC. 2008. Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisal. Nutr Metab (Lond) 5:9.
2. Allain CC, Poon L, Chan C, Richmond W, Fu P. 1974. Enzymatic determination of total serum cholesterol. Clin Chem 20:470-475.
3. Birkhahn RH, Awad S, Thomford NR. 1994. Parenteral monoacetoacetin and liver regeneration interaction after partial hepatectomy in the rat. JPEN J Parenter Enteral Nutr 18:219-224.
4. Bravo R, Rainer F, Blundell PA, Macdonald BH. 1987. Cyclin-PCNA is the auxiliary protein of DNA polymerase δ. Nature 326:515-517. (Pubitemid 17055498)
5. Brunt EM. 2001. Nonalcoholic steatohepatitis: definition and pathology. Semin Liver Dis 21:3-16. (Pubitemid 32240482)
6. Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. 1999. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 94:2467-2474. (Pubitemid 29420675)
7. Contos MJ, Choudhury J, Mills AS, Sanyal AJ. 2004. The histological spectrum of nonalcoholic fatty liver disease. Clin Liver Dis 8:481-500. (Pubitemid 39141138)
8. Dajani OF, Refsnes M, Guren TK, Horn RS, Thoresen GH, Christoffersen T. 1994. Elevated glucose concentrations inhibit DNA synthesis and expression of c-Myc in cultured hepatocytes. Biochem Biophys Res Commun 202:1476-1482. (Pubitemid 24265934)
9. Day CP, James OFW. 1998. Steatohepatitis: a tale of 2 "hits"? Gastroenterology 114:842-845.
10. Delahunty TJ, Rubinstein D. 1970. Accumulation and release of triglycerides by rat liver following partial hepatectomy. J Lipid Res 11:536-543.
11. Dixon JB, Bhathal PS, O'Brien PE. 2001. Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. Gastroenterology 121:91-100. (Pubitemid 32591518)
12. Falck-Ytter Y, Younossi ZM, Marchesini G, McCullough AJ. 2001. Clinical features and natural history of nonalcoholic steatosis syndromes. Semin Liver Dis 21:17-26. (Pubitemid 32240483)
13. Fernandez ML. 2001. Guinea pigs as models for cholesterol and lipoprotein metabolism. J Nutr 131:10-20. (Pubitemid 32060616)
14. Fernandez ML, McNamara DJ. 1989. Dietary fat mediated changes in hepatic apo B/E receptors in the guinea pig. Metabolism 38:1094-1102.
15. Folch J, Lees M, Sloane Stanley GH. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226:497-509.
16. Gebhardt R. 1992. Metabolic zonation of the liver: regulation and implications for liver functions. Pharmacol Ther 53:275-354.
17. Greenwell A, Foley JF, Maronpot RR. 1991. An enhancement method for immunohistochemical staining of proliferating cell nuclear antigen in archival rodent tissues. Cancer Lett 59:251-256.
18. Holecek M. 1999. Nutritional modulation of liver regeneration by carbohydrates, lipids, and amino acids: a review. Nutrition 15:784-788. (Pubitemid 29461026)
19. Laffel L. 1999. Ketone bodies: a review of physiology, pathophysiology, and application of monitoring to diabetes. Diabetes Metab Res Rev 15:412-426. (Pubitemid 30066228)
20. Lazo M, Clark JM. 2008. The epidemiology of nonalcoholic fatty liver disease: a global perspective. Semin Liver Dis 28:339-350.
21. 2 inhibitor, reduces atherosclerosis in guinea pigs. BMC Cardiovasc Disord 9:7.
22. Lin EC, Fernandez ML, McNamara DJ. 1992. Dietary fat type and cholesterol quantity interact to affect cholesterol metabolism in guinea pigs. J Nutr 122:2019-2029.
23. Ludwig J, Viggiano TR, McGill DB, Oh BJ. 1980. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 55:434-438. (Pubitemid 10057164)
24. Marí M, Caballero F, Colell A, Morales A, Caballeria J, Fernandez A, Enrich C, Fernandez-Checa JC, García-Ruiz C. 2006. Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis. Cell Metab 4:185-198. (Pubitemid 44307975)
25. Michalopoulos GK. 2007. Liver regeneration. J Cell Physiol 213:286-300. (Pubitemid 47509705)
26. Neuschwander-Tetri BA, Caldwell SH. 2003. Nonalcoholic steatohepatitis: summary of an AASLD Single-Topic Conference. Hepatology 37:1202-1219. (Pubitemid 36538699)
27. Puri P, Baillie RA, Wiest MM, Mirshahi F, Choudhury J, Cheung O, Sargeant C, Contos MJ, Sanyal AJ. 2007. A lipidomic analysis of nonalcoholic fatty liver disease. Hepatology 46:1081-1090. (Pubitemid 350144772)
28. Solga S, Alkhuraishe AR, Clark JM, Torbenson M, Greenwald A, Diehl AM, Magnuson T. 2004. Dietary composition and nonalcoholic fatty liver disease. Dig Dis Sci 49:1578-1583. (Pubitemid 39335538)
29. Schofield PS, Sugden MC, Corstorphine CG, Zammit VA. 1987. Altered interactions between lipogenesis and fatty acid oxidation in regenerating rat liver. Biochem J 241:469-474. (Pubitemid 17234184)
30. Tendler D, Lin S, Yancy WS Jr, Mavropoulos J, Sylvestre P, Rockey DC, Westman EC. 2007. The effect of a low-carbohydrate, ketogenic diet on nonalcoholic fatty liver disease: a pilot study. Dig Dis Sci 52:589-593. (Pubitemid 46202845)
31. Torres-Gonzalez M, Shrestha S, Sharman M, Freake HC, Volek JS, Fernandez ML. 2007. Carbohydrate restriction alters hepatic cholesterol metabolism in guinea pigs fed a hypercholesterolemic diet. J Nutr 137:2219-2223. (Pubitemid 47529580)
32. Tijburg LB, Nyathi CB, Meijer GW, Geelen MJ. 1991. Biosynthesis and secretion of triacylglycerol in rat liver after partial hepatectomy. Biochem J 277:723-728.
33. Warnick GR, Benderson J, Albers JJ. 1982. Dextran-sulfate-Mg- precipitation procedure for quantitation of high-density-lipoprotein cholesterol. Clin Chem 28:1379-1388. (Pubitemid 12125081)
34. Wolf HK, Michalopoulos GK. 1992. Hepatocyte regeneration in acute fulminant and nonfulminant hepatitis: a study of proliferating cell nuclear antigen expression. Hepatology 15:707-713.
35. Zelber-Sagi S, Nitzan-Kaluski D, Goldsmith R, Webb M, Blendis L, Halpern Z, Oren R. 2007. Long-term nutritional intake and the risk for nonalcoholic fatty liver disease (NAFLD): a population-based study. J Hepatol 47:711-717. (Pubitemid 47503432)