The microRNA cluster C19MC is deregulated in parathyroid tumours

Journal of Molecular Endocrinology

Volumn 49, Issue 2, 2012, Pages 115-124

  Vaira, Valentina ^a   Elli, Francesca ^a,b   Forno, Irene ^b   Guarnieri, Vito ^c   Verdelli, Chiara ^d   Ferrero, Stefano ^b   Scillitani, Alfredo ^c   Vicentini, Leonardo ^a   Cetani, Filomena ^e   Mantovani, Giovanna ^a   Spada, Anna ^a   Bosari, Silvano ^b   Corbetta, Sabrina ^b  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^d IRCCS POLICLINICO SAN DONATO   (Italy)

^e UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; MICRORNA; MICRORNA 517C; MICRORNA C19MC; PARATHYROID HORMONE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CALCIUM BLOOD LEVEL; CHROMOSOME 19Q; CONTROLLED STUDY; COPY NUMBER VARIATION; EPIGENETICS; FEMALE; GENE AMPLIFICATION; GENE CLUSTER; GENE EXPRESSION; GENE LOCUS; GENOMICS; HUMAN; MALE; METASTASIS; PARATHYROID ADENOMA; PARATHYROID CARCINOMA; PARATHYROID HORMONE BLOOD LEVEL; PRIORITY JOURNAL; PROMOTER REGION; RNA METHYLATION; TUMOR VOLUME; UPREGULATION;

ADENOMA; AGED; CHROMOSOMES, HUMAN, PAIR 19; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; METHYLATION; MICRORNAS; MIDDLE AGED; MULTIGENE FAMILY; PARATHYROID NEOPLASMS; PROMOTER REGIONS, GENETIC; REFERENCE VALUES;

EID: 84866417603     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-11-0189     Document Type: Article

References (31)

1. AugelloC, VairaV, Caruso L, Destro A, MaggioniM, ParkYN, MontorsiM, Santambrogio R, Roncalli M & Bosari S 2012 MicroRNA profiling of hepatocarcinogenesis identifies C19MC cluster as a novel prognostic biomarker in hepatocellular carcinoma. Liver International 32 772-882. (doi:10.1111/j.1478-3231.2012.02795.x)
2. Bondenson L, Grimelius L, DeLellis RA, Lloyd R, Akerstrom G, Larsson C, Arnold A, Eng C, Shane E & Bilezikian JP 2004 Parathyroid carcinoma. In Pathology and Genetics. Tumors of Endocrine Organs. WHO Classification of Tumors, pp 128-132. Eds RA DeLellis, RV Lloyd, PU Heitz & C Eng. Lyon: IARC Press.
3. Bortolin-Cavaille ML, Dance M, Weber M & Cavaille J 2009 C19MC microRNAs are processed from introns of large Pol-II, nonprotein-coding transcripts. Nucleic Acids Research 37 3464-3473. (doi:10.1093/nar/gkp205)
4. Bushati N & Cohen SM 2007 microRNA functions. Annual Review of Cell and Developmental Biology 23 175-205. (doi:10.1146/annurev. cellbio.23.090506.123406)
5. Calin GA & Croce CM 2007 Chromosomal rearrangements and microRNAs: a new cancer link with clinical implications. Journal of Clinical Investigation 117 2059-2066. (doi:10.1172/JCI32577)
6. Carling T, Du Y, Fang W, Corres P & Huang S 2003 Intragenic allelic loss and promoter hypermethylation of the RIZ1 tumor suppressor gene in parathyroid tumors and pheochromocytomas. Surgery 134 932-939. (doi:10.1016/S0039-6060(03)00422-7)
7. Cetani F, Pardi E, Borsari S, Viacava P, Dipollina G, Cinferotti L, Ambrogini E, Gazzero E, Colussi G, Berti P et al. 2004 Genetic analyses of the HRPT2 gene in primary hyperparathyroidism: germline and somatic mutations in familial and sporadic parathyroid tumors. Journal of Clinical Endocrinology and Metabolism 89 5583-5591. (doi:10.1210/jc.2004-0294)
8. Cho WJ, Shin JM, Kim JS, Lee MR, Hong KS, Lee JH, Koo KH, Park JW & Kim KS 2009 miR-372 regulates cell cycle and apoptosis of ags human gastric cancer cell line through direct regulation of LATS2. Molecular Cell 28 521-527. (doi:10.1007/s10059-009-0158-0)
9. Corbetta S, Belicchi M, Pisati F, Meregalli M, Eller-Vainicher C, Vicentini L, Beck-Peccoz P, Spada A & Torrente Y 2009 Expression of parathyroid-specific genes in vascular endothelial progenitors of normal and tumoral parathyroid glands. American Journal of Pathology 175 1200-1207. (doi:10.2353/ajpath.2009.080979)
10. Corbetta S, Vaira V, Guarnieri V, Scillitani A, Eller-VainicherC, Ferrero S, Vicentini L, Chiodini I, Bisceglia M, Beck-Peccoz P et al. 2010 Differential expression of microRNAs in human parathyroid carcinomas compared with normal parathyroid tissue. Endocrine-Related Cancer 17 135-146. (doi:10.1677/ERC-09-0134)
11. Guarnieri V, Scillitani A, Muscarella LA, Battista C, Bonfitto N, Bisceglia M, Minisola S, Mascia ML, D'Agruma L & Cole DEC 2006 Diagnosis of parathyroid tumors in familial isolated hyperparathyroidism with HRPT2 mutation: implications for cancer surveillance. Journal of Clinical Endocrinology and Metabolism 91 2827-2832. (doi:10.1210/jc.2005-1239)
12. Guarnieri V, Bisceglia M, Bonfitto N, Cetani F, Marcocci C, Minisola S, Battista C, Cole DE & Scillitani A 2008 Re: familial hyperparathyroidism: surgical outcome after 30 years of follow-up in three families with germline HRPT2 mutations. Surgery 144 839-840. (doi:10.1016/j.surg.2008.08.008)
13. Juhlin CC, Kiss NB, Villablanca A, Haglund F, Nordenstrom J, Hoog A & Larsson C 2010 Frequent promoter hypermethylation of the APC and RASSF1A tumour suppressors in parathyroid tumours. PLoS ONE 5 e9472. (doi:10.1371/journal.pone.0009472)
14. Kytola S, Farnebo F, Obara T, Isola J, Grimelius L, Farnebo L-O, Sandelin K & Larsson C 2000 Patterns of chromosomal imbalances in parathyroid carcinomas. American Journal of Pathology 157 579-586. (doi:10.1016/S0002-9440(10)64568-3)
15. Laurent LC, Chen J, Ulitsky I, Mueller FJ, Lu C, Shamir R, Fan JB & Loring JF 2008 Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence. Stem Cells 26 1506-1516. (doi:10.1634/stemcells. 2007-1081)
16. Li M, Lee KF, Lu Y, Clarke I, Shih D, Eberhart C, Collins VP, Van Meter T, Picard D, Zhou L et al. 2009a Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors. Cancer Cell 16 533-546. (doi:10.1016/j.ccr. 2009.10.025)
17. Li SS, Yu SL, Kao LP, Tsai ZY, Singh S, Chen BZ, Ho BC, Liu YH & Yang PC 2009b Target identification of microRNAs expressed highly in human embryonic stem cells. Journal of Cellular Biochemistry 106 1020-1030. (doi:10.1002/jcb.22084)
18. Liang Y, Ridzon D, Wong L & Chen C 2007 Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 8 166. (doi:10.1186/1471-2164-8-166)
19. Lin S, Cheung WKC, Chen S, Lu G, Wang Z, Xie D, Li K, Lin MCM & Kung H 2010 Computational identification and characterization of primate-specific microRNAs in human genome. Computational Biology and Chemistry 34 232-241. (doi:10.1016/j.compbiolchem. 2010.08.001)
20. Mantovani G, De Sanctis L, Barbieri AM, Elli FM, Bollati V, Vaira V, Labarile P, Bondioni S, Peverelli E, Lania AG et al. 2010 Pseudohypoparathyroidism and GNAS epigenetic defects: clinical evaluation of Albright hereditary osteodystrophy and molecular analysis in 40 patients. Journal of Clinical Endocrinology and Metabolism 95 651-658. (doi:10.1210/jc.2009-0176)
21. Rahbari R, Holloway AK, Mei He, Khanafshar E, Clark O & Kebebew E 2010 Identification of differentially expressed microRNA in parathyroid tumors. Annals of Surgical Oncology 18 1158-1165. (doi:10.1245/s10434-010-1359-7)
22. Rakheja D, Margraf LR, Tomlinson GE & Schneider NR 2004 Hepatic mesenchymal hamartoma with translocation involving chromosome band 19q13.4: a recurrent abnormality. Cancer Genetics and Cytogenetics 153 60-63. (doi:10.1016/j.cancergencyto.2003.12.004)
23. Ren J, Jin P, Wang E, Marincola FM & Stroncek DF 2009 MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells. Journal of Translational Medicine 7 20. (doi:10.1186/1479-5876-7-20)
24. Rippe V, Dittberner L, Lorenz VN, Driescner N, Nimzyk R, Sendt W, Junker K, Belge G & Bullerdiek J 2010 The two stem cell microRNA gene clusters C19MC and miR-371-3 are activated by specific chromosomal rearrangements in a subgroup of thyroid adenomas. PLoS ONE 5 e9485. (doi:10.1371/journal.pone.0009485)
25. Starker LF, Svedlund J, Udelsman R, Dralle H, Akerstrom G, Westin G, Lifton RP, Bjorklund P & Carling T 2011 The DNA methyloma of benign and malignant parathyroid tumors. Genes, Chromosomes & Cancer 50 735-745. (doi:10.1002/gcc.20895)
26. Suh M-R, Lee Y, Kim JY, Kim S-K, Moon S-H, Lee JY, Cha K-Y, Chung HM, Yoon HS, Moon SY et al. 2004 Human embryonic stem cells express a unique set of microRNAs. Developmental Biology 270 488-498. (doi:10.1016/j.ydbio.2004.02.019)
27. Svedlund J, Auren M, Sundstrom M, Dralle H, Akerstrom G, Bjorklund P & Westin G 2010 Aberrant WNT/b-catenin signalling in parathyroid carcinoma. Molecular Cancer 9 294. (doi:10.1186/1476-4598-9-294)
28. Toffanin S, Alsinet C, Cornella H, Sia D & Llovet JM 2011 microRNAs and the MYC network: a major piece in the puzzle of liver cancer. Gastroenterology 140 2138-2140. (doi:10.1053/j.gastro.2011.04.023)
29. Tsai KW, Kao HW, Chen HC, Chen SJ & Lin WC 2009 Epigenetic control of the expression of a primate-specific microRNA cluster in human cancer cells. Epigenetics 4 587-592. (doi:10.4161/epi.4.8. 10230)
30. Voorhoeve PM, le Sage C, Schrier M, Gillis AJ, Stoop H, Nagel R, Liu YP, van Duijse J, Drost J, Griekspoor A et al. 2006 A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell 124 1169-1181. (doi:10.1016/j.cell.2006.02.037)
31. Wang J, Liu X, Wu H, Ni P, Gu Z, Qiao Y, Chen N, Sun F & Fan Q 2010 CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer. Nucleic Acids Research 38 5366-5383. (doi:10.1093/nar/gkq285)