Multiple Loci Associated with Renal Function in African Americans

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Shriner, Daniel ^a   Herbert, Alan ^b   Doumatey, Ayo P ^a   Zhou, Jie ^a   Huang, Hanxia ^a   Erdos, Michael R ^a   Chen, Guanjie ^a   Gerry, Norman P ^c   Christman, Michael F ^c   Adeyemo, Adebowale ^a   Rotimi, Charles N ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Laboratory of Molecular and Cellular Biology of Hematopoiesis   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN; APOLIPOPROTEIN L1; UNCLASSIFIED DRUG;

ADULT; AFRICAN AMERICAN; ARTICLE; CHRONIC KIDNEY DISEASE; EFFECT SIZE; ETHNIC GROUP; EUROPEAN AMERICAN; FEMALE; FOLLOW UP; GENE FREQUENCY; GENE LOCUS; GLOMERULUS FILTRATION RATE; HUMAN; INCIDENCE; KIDNEY FAILURE; KIDNEY FUNCTION; MALE; PHENOTYPIC VARIATION; REGRESSION ANALYSIS; UNITED STATES;

AFRICAN AMERICANS; FEMALE; GENEALOGY AND HERALDRY; GENETIC LOCI; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY; KIDNEY FUNCTION TESTS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84866415741     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0045112     Document Type: Article

References (30)

1. Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, et al. (2007) Prevalence of chronic kidney disease in the United States. JAMA 298: 2038-2047.
2. National Kidney Foundation (2002) K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 39: S1-S266.
3. Tarver-Carr ME, Powe NR, Eberhardt MS, LaVeist TA, Kington RS, et al. (2002) Excess risk of chronic kidney disease among African-American versus white subjects in the United States: a population-based study of potential explanatory factors. J Am Soc Nephrol 13: 2363-2370.
4. Fox CS, Yang Q, Cupples LA, Guo C-Y, Larson MG, et al. (2004) Genomewide linkage analysis to serum creatinine, GFR, and creatinine clearance in a community-based population: the Framingham Heart Study. J Am Soc Nephrol 15: 2457-2461.
5. Langefeld CD, Beck SR, Bowden DW, Rich SS, Wagenknecht LE, et al. (2004) Heritability of GFR and albuminuria in Caucasians with type 2 diabetes mellitus. Am J Kidney Dis 43: 796-800.
6. Köttgen A, Glazer NL, Dehghan A, Hwang S-J, Katz R, et al. (2009) Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet 41: 712-717.
7. Köttgen A, Pattaro C, Boger CA, Fuchsberger C, Olden M, et al. (2010) New loci associated with kidney function and chronic kidney disease. Nat Genet 42: 376-384.
8. Kao WH, Klag MJ, Meoni LA, Reich D, Berthier-Schaad Y, et al. (2008) MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nat Genet 40: 1185-1192.
9. Kopp JB, Smith MW, Nelson GW, Johnson RC, Freedman BI, et al. (2008) MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis. Nat Genet 40: 1175-1184.
10. Genovese G, Friedman DJ, Ross MD, Lecordier L, Uzureau P, et al. (2010) Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science 329: 841-845.
11. Shriner D, Adeyemo A, Rotimi CN, (2011) Joint ancestry and association testing in admixed individuals. PLoS Comput Biol 7: e1002325.
12. Ramos E, Chen G, Shriner D, Doumatey A, Gerry NP, et al. (2011) Replication of genome-wide association studies (GWAS) loci for fasting plasma glucose in African-Americans. Diabetologia 54: 783-788.
13. Gauderman WJ, (2002) Sample size requirements for matched case-control studies of gene-environment interaction. Stat Med 21: 35-50.
14. Rosenberg NA, Nordborg M, (2006) A general population-genetic model for the production by population structure of spurious genotype-phenotype associations in discrete, admixed or spatially distributed populations. Genetics 173: 1665-1678.
15. McClellan J, King M-C, (2010) Why it is time to sequence. Cell 142: 353-355.
16. Liu CT, Garnaas MK, Tin A, Kottgen A, Franceschini N, et al. (2011) Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet 7: e1002264.
17. Adeyemo A, Gerry N, Chen G, Herbert A, Doumatey A, et al. (2009) A genome-wide association study of hypertension and blood pressure in African Americans. PLoS Genet 5: e1000564.
18. Sankararaman S, Sridhar S, Kimmel G, Halperin E, (2008) Estimating local ancestry in admixed populations. Am J Hum Genet 82: 290-303.
19. Falush D, Stephens M, Pritchard JK, (2003) Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics 164: 1567-1587.
20. Chen G, Shriner D, Zhou J, Doumatey A, Huang H, et al. (2010) Development of admixture mapping panels for African Americans from commercial high-density SNP arrays. BMC Genomics 11: 417.
21. Deo RC, Reich D, Tandon A, Akylbekova E, Patterson N, et al. (2009) Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. PLoS Genet 5: e1000342.
22. Bretherton CS, Widmann M, Dymnikov VP, Wallace JM, Bladé I, (1999) The effective number of spatial degrees of freedom of a time-varying field. J Climate 12: 1990-2009.
23. The Wellcome Trust Case Control Consortium, (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678.
24. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, et al. (1999) A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Ann Intern Med 130: 461-470.
25. Qin H, Morris N, Kang SJ, Li M, Tayo B, et al. (2010) Interrogating local population structure for fine mapping in genome-wide association studies. Bioinformatics 26: 2961-2968.
26. Wang X, Zhu X, Qin H, Cooper RS, Ewens WJ, et al. (2011) Adjustment for local ancestry in genetic association analysis of admixed populations. Bioinformatics 27: 670-677.
27. Shriner D, Adeyemo A, Ramos E, Chen G, Rotimi CN, (2011) Mapping of disease-associated variants in admixed populations. Genome Biol 12: 223.
28. de Bakker PI, Ferreira MA, Jia X, Neale BM, Raychaudhuri S, et al. (2008) Practical aspects of imputation-driven meta-analysis of genome-wide association studies. Hum Mol Genet 17: R122-R128.
29. R Development Core Team (2011) R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing.
30. Shriner D, (2011) Investigating population stratification and admixture using eigenanalysis of dense genotypes. Heredity 107: 413-420.