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Volumn 36, Issue 6, 2012, Pages 2839-2848

Serotonin transporter inhibition attenuates l-DOPA-induced dyskinesia without compromising l-DOPA efficacy in hemi-parkinsonian rats

Author keywords

Abnormal involuntary movements; Dopamine; Parkinson's disease; Selective serotonin reuptake inhibitors

Indexed keywords

APOMORPHINE; BENSERAZIDE; CITALOPRAM; FLUOXETINE; LEVODOPA; OXIDOPAMINE; PAROXETINE; SEROTONIN UPTAKE INHIBITOR;

EID: 84866412870     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2012.08202.x     Document Type: Article
Times cited : (70)

References (70)
  • 1
    • 0035353725 scopus 로고    scopus 로고
    • Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature
    • Ahlskog, J.E. & Muenter, M.D. (2001) Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature. Mov. Disord., 16, 448-458.
    • (2001) Mov. Disord. , vol.16 , pp. 448-458
    • Ahlskog, J.E.1    Muenter, M.D.2
  • 2
    • 0028984349 scopus 로고
    • l-DOPA is converted to dopamine in serotonergic fibers of the striatum of the rat: a double-labeling immunofluorescence study
    • Arai, R., Karasawa, N., Geffard, M. & Nagatsu, I. (1995) l-DOPA is converted to dopamine in serotonergic fibers of the striatum of the rat: a double-labeling immunofluorescence study. Neurosci. Lett., 195, 195-198.
    • (1995) Neurosci. Lett. , vol.195 , pp. 195-198
    • Arai, R.1    Karasawa, N.2    Geffard, M.3    Nagatsu, I.4
  • 4
    • 73049129373 scopus 로고
    • The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia
    • Birkmayer, W. & Hornykiewicz, O. (1961) The L-3, 4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia. Wien. Klin. Wochenschr., 73, 787-788.
    • (1961) Wien. Klin. Wochenschr. , vol.73 , pp. 787-788
    • Birkmayer, W.1    Hornykiewicz, O.2
  • 5
    • 33744478909 scopus 로고    scopus 로고
    • MDMA and fenfluramine reduce l-DOPA-induced dyskinesia via indirect 5-HT1A receptor stimulation
    • Bishop, C., Taylor, J.L., Kuhn, D.M., Eskow, K.L., Park, J.Y. & Walker, P.D. (2006) MDMA and fenfluramine reduce l-DOPA-induced dyskinesia via indirect 5-HT1A receptor stimulation. Eur. J. Neurosci., 23, 2669-2676.
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 2669-2676
    • Bishop, C.1    Taylor, J.L.2    Kuhn, D.M.3    Eskow, K.L.4    Park, J.Y.5    Walker, P.D.6
  • 6
    • 66049100759 scopus 로고    scopus 로고
    • Contribution of the striatum to the effects of 5-HT1A receptor stimulation in l-DOPA-treated hemiparkinsonian rats
    • Bishop, C., Krolewski, D.M., Eskow, K.L., Barnum, C.J., Dupre, K.B., Deak, T. & Walker, P.D. (2009) Contribution of the striatum to the effects of 5-HT1A receptor stimulation in l-DOPA-treated hemiparkinsonian rats. J. Neurosci. Res., 87, 1645-1958.
    • (2009) J. Neurosci. Res. , vol.87 , pp. 1645-1958
    • Bishop, C.1    Krolewski, D.M.2    Eskow, K.L.3    Barnum, C.J.4    Dupre, K.B.5    Deak, T.6    Walker, P.D.7
  • 7
    • 0015238613 scopus 로고
    • Classification of monoamine neurones in the rat mesencephalon: distribution of a new monoamine neurone system
    • Björklund, A., Falck, B. & Stenevi, U. (1971) Classification of monoamine neurones in the rat mesencephalon: distribution of a new monoamine neurone system. Brain Res., 32, 269-285.
    • (1971) Brain Res. , vol.32 , pp. 269-285
    • Björklund, A.1    Falck, B.2    Stenevi, U.3
  • 9
    • 0036208185 scopus 로고    scopus 로고
    • Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex
    • Bymaster, F.P., Zhang, W., Carter, P.A., Shaw, J., Chernet, E., Phebus, L., Wong, D.T. & Perry, K.W. (2002) Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex. Psychopharmacology, 160, 353-361.
    • (2002) Psychopharmacology , vol.160 , pp. 353-361
    • Bymaster, F.P.1    Zhang, W.2    Carter, P.A.3    Shaw, J.4    Chernet, E.5    Phebus, L.6    Wong, D.T.7    Perry, K.W.8
  • 10
    • 0026669546 scopus 로고
    • Does fluoxetine exacerbate Parkinson's disease?
    • Caley, C.F. & Friedman, J.H. (1992) Does fluoxetine exacerbate Parkinson's disease?J. Clin. Psychiatry, 53, 278-282.
    • (1992) J. Clin. Psychiatry , vol.53 , pp. 278-282
    • Caley, C.F.1    Friedman, J.H.2
  • 11
    • 34447627504 scopus 로고    scopus 로고
    • Dopamine released from 5-HT terminals is the cause of l-DOPA-induced dyskinesia in parkinsonian rats
    • Carta, M., Carlsson, T., Kirik, D. & Björklund, A. (2007) Dopamine released from 5-HT terminals is the cause of l-DOPA-induced dyskinesia in parkinsonian rats. Brain, 130, 1819-1833.
    • (2007) Brain , vol.130 , pp. 1819-1833
    • Carta, M.1    Carlsson, T.2    Kirik, D.3    Björklund, A.4
  • 12
    • 0036637271 scopus 로고    scopus 로고
    • Animal models of neurological deficits: how relevant is the rat
    • Cenci, M.A., Whishaw, I.Q. & Schallert, T. (2002) Animal models of neurological deficits: how relevant is the rat. Nat. Rev. Neurosci., 3, 574-579.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 574-579
    • Cenci, M.A.1    Whishaw, I.Q.2    Schallert, T.3
  • 14
    • 0032889986 scopus 로고    scopus 로고
    • Biochemical and anatomical characterization of forepaw adjusting steps in rat models of Parkinson's disease: studies on medial forebrain bundle and striatal lesions
    • Chang, J.W., Wachtel, S.R., Young, D. & Kang, U.J. (1999) Biochemical and anatomical characterization of forepaw adjusting steps in rat models of Parkinson's disease: studies on medial forebrain bundle and striatal lesions. Neuroscience, 88, 617-628.
    • (1999) Neuroscience , vol.88 , pp. 617-628
    • Chang, J.W.1    Wachtel, S.R.2    Young, D.3    Kang, U.J.4
  • 15
    • 18844447522 scopus 로고    scopus 로고
    • Short-term paroxetine treatment does not alter the motor response to levodopa in PD
    • Chung, K.A., Carlson, N.E. & Nutt, J.G. (2005) Short-term paroxetine treatment does not alter the motor response to levodopa in PD. Neurology, 64, 1797-1798.
    • (2005) Neurology , vol.64 , pp. 1797-1798
    • Chung, K.A.1    Carlson, N.E.2    Nutt, J.G.3
  • 16
    • 33947302427 scopus 로고    scopus 로고
    • Modulation of l-DOPA-induced abnormal involuntary movements by clinically tested compounds: further validation of the rat dyskinesia model
    • Dekundy, A., Lundblad, M., Danysz, W. & Cenci, M.A. (2007) Modulation of l-DOPA-induced abnormal involuntary movements by clinically tested compounds: further validation of the rat dyskinesia model. Behav. Brain Res., 179, 76-89.
    • (2007) Behav. Brain Res. , vol.179 , pp. 76-89
    • Dekundy, A.1    Lundblad, M.2    Danysz, W.3    Cenci, M.A.4
  • 17
    • 0017870479 scopus 로고
    • Pharmacology and neurochemistry of apomorphine
    • Di Chiara, G. & Gessa, G.L. (1978) Pharmacology and neurochemistry of apomorphine. Adv. Pharmacol. Chemother., 15, 87-160.
    • (1978) Adv. Pharmacol. Chemother. , vol.15 , pp. 87-160
    • Di Chiara, G.1    Gessa, G.L.2
  • 18
    • 34447532344 scopus 로고    scopus 로고
    • The differential effects of 5-HT(1A) receptor stimulation on dopamine receptor-mediated abnormal involuntary movements and rotations in the primed hemiparkinsonian rat
    • Dupre, K.B., Eskow, K.L., Negron, G. & Bishop, C. (2007) The differential effects of 5-HT(1A) receptor stimulation on dopamine receptor-mediated abnormal involuntary movements and rotations in the primed hemiparkinsonian rat. Brain Res., 1158, 135-143.
    • (2007) Brain Res. , vol.1158 , pp. 135-143
    • Dupre, K.B.1    Eskow, K.L.2    Negron, G.3    Bishop, C.4
  • 19
    • 0029431964 scopus 로고
    • Levodopa-induced dyskinesias are improved by fluoxetine
    • Durif, F., Vidailhet, M., Bonnet, A.M., Blin, J. & Agid, Y. (1995) Levodopa-induced dyskinesias are improved by fluoxetine. Neurology, 45, 1855-1858.
    • (1995) Neurology , vol.45 , pp. 1855-1858
    • Durif, F.1    Vidailhet, M.2    Bonnet, A.M.3    Blin, J.4    Agid, Y.5
  • 20
    • 34547115255 scopus 로고    scopus 로고
    • The partial 5-HT1A agonist buspirone reduces the expression and development of l-DOPA-induced dyskinesia in rats and improves l-DOPA efficacy
    • Eskow, K., Gupta, V., Alam, S., Park, J. & Bishop, C. (2007) The partial 5-HT1A agonist buspirone reduces the expression and development of l-DOPA-induced dyskinesia in rats and improves l-DOPA efficacy. Pharmacol. Biochem. Behav., 87, 306-314.
    • (2007) Pharmacol. Biochem. Behav. , vol.87 , pp. 306-314
    • Eskow, K.1    Gupta, V.2    Alam, S.3    Park, J.4    Bishop, C.5
  • 21
    • 67449107965 scopus 로고    scopus 로고
    • The role of the dorsal raphe nucleus in the development, expression, and treatment of L-dopa-induced dyskinesia in hemiparkinsonian rats
    • Eskow, K.L., Dupre, K.B., Barnum, C.J., Dickinson, S.O., Park, J.Y. & Bishop, C. (2009) The role of the dorsal raphe nucleus in the development, expression, and treatment of L-dopa-induced dyskinesia in hemiparkinsonian rats. Synapse, 63, 610-620.
    • (2009) Synapse , vol.63 , pp. 610-620
    • Eskow, K.L.1    Dupre, K.B.2    Barnum, C.J.3    Dickinson, S.O.4    Park, J.Y.5    Bishop, C.6
  • 22
    • 84855341776 scopus 로고    scopus 로고
    • l-DOPA-induced dyskinesia and abnormal signaling in striatal medium spiny neurons: focus on dopamine D1 receptor-mediated transmission
    • Feyder, M., Bonito-Oliva, A. & Fisone, G. (2011) l-DOPA-induced dyskinesia and abnormal signaling in striatal medium spiny neurons: focus on dopamine D1 receptor-mediated transmission. Front. Behav. Neurosci., 5, 71.
    • (2011) Front. Behav. Neurosci. , vol.5 , pp. 71
    • Feyder, M.1    Bonito-Oliva, A.2    Fisone, G.3
  • 23
    • 0035412923 scopus 로고    scopus 로고
    • Neural mechanisms underlying peak-dose dyskinesia induced by levodopa and apomorphine are distinct: evidence from the effects of the alpha(2) adrenergic adrenoreceptor antagonist idazoxan
    • Fox, S.H., Henry, B., Hill, M.P., Peggs, G., Crossman, A.P. & Brotchie, J.M. (2001) Neural mechanisms underlying peak-dose dyskinesia induced by levodopa and apomorphine are distinct: evidence from the effects of the alpha(2) adrenergic adrenoreceptor antagonist idazoxan. Mov. Disord., 16, 642-650.
    • (2001) Mov. Disord. , vol.16 , pp. 642-650
    • Fox, S.H.1    Henry, B.2    Hill, M.P.3    Peggs, G.4    Crossman, A.P.5    Brotchie, J.M.6
  • 24
    • 10344236071 scopus 로고    scopus 로고
    • Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias
    • de la Fuente-Fernández, R., Sossi, V., Huang, Z., Furtado, S., Lu, J.Q., Calne, D.B., Ruth, T.J. & Stoessl, A.J. (2004) Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias. Brain, 127, 2747-2754.
    • (2004) Brain , vol.127 , pp. 2747-2754
    • de la Fuente-Fernández, R.1    Sossi, V.2    Huang, Z.3    Furtado, S.4    Lu, J.Q.5    Calne, D.B.6    Ruth, T.J.7    Stoessl, A.J.8
  • 25
    • 79959869606 scopus 로고    scopus 로고
    • Modulation of striatal projection systems by dopamine
    • Gerfen, C.R. & Surmeier, D.J. (2011) Modulation of striatal projection systems by dopamine. Annu. Rev. Neurosci., 34, 441-466.
    • (2011) Annu. Rev. Neurosci. , vol.34 , pp. 441-466
    • Gerfen, C.R.1    Surmeier, D.J.2
  • 26
    • 33847757879 scopus 로고    scopus 로고
    • Sarizotan as a treatment for dyskinesias in Parkinson's disease: a double-blind placebo-controlled trial
    • Goetz, C.G., Damier, P., Hicking, C., Laska, E., Müller, T., Olanow, C.W., Rascol, O. & Russ, H. (2007) Sarizotan as a treatment for dyskinesias in Parkinson's disease: a double-blind placebo-controlled trial. Mov. Disord., 22, 179-186.
    • (2007) Mov. Disord. , vol.22 , pp. 179-186
    • Goetz, C.G.1    Damier, P.2    Hicking, C.3    Laska, E.4    Müller, T.5    Olanow, C.W.6    Rascol, O.7    Russ, H.8
  • 27
    • 0030813322 scopus 로고    scopus 로고
    • Risk assessment behaviour: evaluation of utility in the study of 5-HT-related drugs in the rat elevated plus maze
    • Griebel, G., Rodgers, R.J., Perrault, G. & Sanger, D.J. (1997) Risk assessment behaviour: evaluation of utility in the study of 5-HT-related drugs in the rat elevated plus maze. Pharmacol. Biochem. Behav., 57, 817-827.
    • (1997) Pharmacol. Biochem. Behav. , vol.57 , pp. 817-827
    • Griebel, G.1    Rodgers, R.J.2    Perrault, G.3    Sanger, D.J.4
  • 28
    • 69849101826 scopus 로고    scopus 로고
    • Chronic citalopram administration causes a sustained suppression of serotonin synthesis in the mouse forebrain
    • Honig, G., Jongsma, M.E., van der Hart, M.C. & Tecott, L.H. (2009) Chronic citalopram administration causes a sustained suppression of serotonin synthesis in the mouse forebrain. PLoS One, 4, e6797.
    • (2009) PLoS One , vol.4
    • Honig, G.1    Jongsma, M.E.2    van der Hart, M.C.3    Tecott, L.H.4
  • 29
    • 80052009184 scopus 로고    scopus 로고
    • Abnormal bidirectional plasticity-like effects in Parkinson's disease
    • Huang, Y.Z., Rothwell, J.C., Lu, C.S., Chuang, W.L. & Chen, R.S. (2011) Abnormal bidirectional plasticity-like effects in Parkinson's disease. Brain, 134, 2312-2320.
    • (2011) Brain , vol.134 , pp. 2312-2320
    • Huang, Y.Z.1    Rothwell, J.C.2    Lu, C.S.3    Chuang, W.L.4    Chen, R.S.5
  • 30
    • 79956318374 scopus 로고    scopus 로고
    • Characterization of 3,4-methylenedioxymethamphetamine (MDMA) enantiomers in vitro and in the MPTP-lesioned primate: R-MDMA reduces severity of dyskinesia, whereas S-MDMA extends duration of ON-time
    • Huot, P., Johnston, T.H., Lewis, K.D., Koprich, J.B., Reyes, M.G., Fox, S.H., Piggott, M.J. & Brotchie, J.M. (2011) Characterization of 3, 4-methylenedioxymethamphetamine (MDMA) enantiomers in vitro and in the MPTP-lesioned primate: R-MDMA reduces severity of dyskinesia, whereas S-MDMA extends duration of ON-time. J. Neurosci., 31, 7190-7198.
    • (2011) J. Neurosci. , vol.31 , pp. 7190-7198
    • Huot, P.1    Johnston, T.H.2    Lewis, K.D.3    Koprich, J.B.4    Reyes, M.G.5    Fox, S.H.6    Piggott, M.J.7    Brotchie, J.M.8
  • 31
    • 0141919606 scopus 로고    scopus 로고
    • 3,4-methylenedioxymethamphetamine (ecstasy) inhibits dyskinesia expression and normalizes motor activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates
    • Iravani, M.M., Jackson, M.J., Kuoppamäki, M., Smith, L.A. & Jenner, P. (2003) 3, 4-methylenedioxymethamphetamine (ecstasy) inhibits dyskinesia expression and normalizes motor activity in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-treated primates. J. Neurosci., 23, 9107-9115.
    • (2003) J. Neurosci. , vol.23 , pp. 9107-9115
    • Iravani, M.M.1    Jackson, M.J.2    Kuoppamäki, M.3    Smith, L.A.4    Jenner, P.5
  • 33
    • 0033979540 scopus 로고    scopus 로고
    • Reserpine treatment prevents increases in extracellular striatal dopamine following l-DOPA administration in ras with nigrostriatal denervation
    • Kannari, K., Tanaka, K., Maeda, T., Tomiyama, M., Suda, T. & Matsunaga, M. (2000) Reserpine treatment prevents increases in extracellular striatal dopamine following l-DOPA administration in ras with nigrostriatal denervation. J. Neurochem., 74, 263-269.
    • (2000) J. Neurochem. , vol.74 , pp. 263-269
    • Kannari, K.1    Tanaka, K.2    Maeda, T.3    Tomiyama, M.4    Suda, T.5    Matsunaga, M.6
  • 34
    • 33646822115 scopus 로고    scopus 로고
    • Reuptake of l-DOPA-derived extracellular dopamine in the striatum with dopaminergic denervation via serotonin transporters
    • Kannari, K., Shen, H., Arai, A., Tomiyama, M. & Baba, M. (2006) Reuptake of l-DOPA-derived extracellular dopamine in the striatum with dopaminergic denervation via serotonin transporters. Neurosci. Lett., 402, 62-65.
    • (2006) Neurosci. Lett. , vol.402 , pp. 62-65
    • Kannari, K.1    Shen, H.2    Arai, A.3    Tomiyama, M.4    Baba, M.5
  • 35
    • 0022644209 scopus 로고
    • A semiautomated analysis method for catecholamines, indoleamines, and some prominent metabolites in microdissected regions of the nervous system: an isocratic HPLC technique employing coulometric detection and minimal sample preparation
    • Kilpatrick, I.C., Jones, M.W. & Phillipson, O.T. (1986) A semiautomated analysis method for catecholamines, indoleamines, and some prominent metabolites in microdissected regions of the nervous system: an isocratic HPLC technique employing coulometric detection and minimal sample preparation. J. Neurochem., 46, 1865-1876.
    • (1986) J. Neurochem. , vol.46 , pp. 1865-1876
    • Kilpatrick, I.C.1    Jones, M.W.2    Phillipson, O.T.3
  • 36
    • 0028332869 scopus 로고
    • Differential regulation of serotonin (5-HT) release in the striatum and hippocampus by 5-HT1A autoreceptors of the dorsal and median raphe nuclei
    • Kreiss, D.S. & Lucki, I. (1994) Differential regulation of serotonin (5-HT) release in the striatum and hippocampus by 5-HT1A autoreceptors of the dorsal and median raphe nuclei. J. Pharmacol. Exp. Ther., 269, 1268-1279.
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , pp. 1268-1279
    • Kreiss, D.S.1    Lucki, I.2
  • 37
    • 40949084814 scopus 로고    scopus 로고
    • The role of anxiety in the development of levodopa-induced dyskinesias in an animal model of Parkinson's disease, and the effect of chronic treatment with the selective serotonin reuptake inhibitor citalopram
    • Kuan, W.L., Zhao, J.W. & Barker, R.A. (2008) The role of anxiety in the development of levodopa-induced dyskinesias in an animal model of Parkinson's disease, and the effect of chronic treatment with the selective serotonin reuptake inhibitor citalopram. Psychopharmacology, 197, 279-293.
    • (2008) Psychopharmacology , vol.197 , pp. 279-293
    • Kuan, W.L.1    Zhao, J.W.2    Barker, R.A.3
  • 38
    • 79955769299 scopus 로고    scopus 로고
    • Dopamine transport by the serotonin transporter: a mechanistically distinct mode of substrate translocation
    • Larsen, M.B., Sonders, M.S., Mortensen, O.V., Larson, G.A., Zahniser, N.R. & Amara, S.G. (2011) Dopamine transport by the serotonin transporter: a mechanistically distinct mode of substrate translocation. J. Neurosci., 31, 6605-6615.
    • (2011) J. Neurosci. , vol.31 , pp. 6605-6615
    • Larsen, M.B.1    Sonders, M.S.2    Mortensen, O.V.3    Larson, G.A.4    Zahniser, N.R.5    Amara, S.G.6
  • 39
    • 0029806639 scopus 로고    scopus 로고
    • Movement disorders associated with the serotonin selective reuptake inhibitors
    • Leo, R.J. (1996) Movement disorders associated with the serotonin selective reuptake inhibitors. J. Clin. Psychiatry, 57, 449-454.
    • (1996) J. Clin. Psychiatry , vol.57 , pp. 449-454
    • Leo, R.J.1
  • 41
    • 79956197316 scopus 로고    scopus 로고
    • Behavioral and cellular modulation of l-DOPA-induced dyskinesia by β-adrenoceptor receptor blockade in the 6-OHDA lesioned rat
    • Lindenbach, D., Ostock, C.Y., Eskow Jaunarajs, K.L., Dupre, K.B., Barnum, C.J., Bhide, N. & Bishop, C. (2011) Behavioral and cellular modulation of l-DOPA-induced dyskinesia by β-adrenoceptor receptor blockade in the 6-OHDA lesioned rat. J. Pharmacol. Exp. Ther., 337, 755-765.
    • (2011) J. Pharmacol. Exp. Ther. , vol.337 , pp. 755-765
    • Lindenbach, D.1    Ostock, C.Y.2    Eskow Jaunarajs, K.L.3    Dupre, K.B.4    Barnum, C.J.5    Bhide, N.6    Bishop, C.7
  • 42
    • 77349086589 scopus 로고    scopus 로고
    • l-DOPA-induced dopamine efflux in the striatum and the substantia nigra in a rat model of Parkinson's disease: temporal and quantitative relationship to the expression of dyskinesia
    • Lindgren, H.S., Andersson, D.R., Lagerkvist, S., Nissbrandt, H. & Cenci, M.A. (2010) l-DOPA-induced dopamine efflux in the striatum and the substantia nigra in a rat model of Parkinson's disease: temporal and quantitative relationship to the expression of dyskinesia. J. Neurochem., 112, 1465-1476.
    • (2010) J. Neurochem. , vol.112 , pp. 1465-1476
    • Lindgren, H.S.1    Andersson, D.R.2    Lagerkvist, S.3    Nissbrandt, H.4    Cenci, M.A.5
  • 43
    • 0036459952 scopus 로고    scopus 로고
    • Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease
    • Lundblad, M., Andersson, M., Winkler, C., Kirik, D., Wierup, N. & Cenci, M.A. (2002) Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease. Eur. J. Neurosci., 15, 120-132.
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 120-132
    • Lundblad, M.1    Andersson, M.2    Winkler, C.3    Kirik, D.4    Wierup, N.5    Cenci, M.A.6
  • 44
    • 20144378889 scopus 로고    scopus 로고
    • Serotonergic hyperinnervation into the dopaminergic denervated striatum compensates for dopamine conversion from exogenously administered l-DOPA
    • Maeda, T., Nagata, K., Yoshida, Y. & Kannari, K. (2005) Serotonergic hyperinnervation into the dopaminergic denervated striatum compensates for dopamine conversion from exogenously administered l-DOPA. Brain Res., 1046, 230-233.
    • (2005) Brain Res. , vol.1046 , pp. 230-233
    • Maeda, T.1    Nagata, K.2    Yoshida, Y.3    Kannari, K.4
  • 47
    • 77549083048 scopus 로고    scopus 로고
    • Serotonergic neurons mediate ectopic release of dopamine induced by L-DOPA in a rat model of Parkinson's disease
    • Navailles, S., Bioulac, B., Gross, C. & De Deurwaerdère, P. (2010) Serotonergic neurons mediate ectopic release of dopamine induced by L-DOPA in a rat model of Parkinson's disease. Neurobiol. Dis., 38, 136-143.
    • (2010) Neurobiol. Dis. , vol.38 , pp. 136-143
    • Navailles, S.1    Bioulac, B.2    Gross, C.3    De Deurwaerdère, P.4
  • 48
    • 0014930392 scopus 로고
    • l-DOPA-induced release of cerebral monoamines
    • Ng, K.Y., Chase, T.N., Colburn, R.W. & Kopin, I.J. (1970) l-DOPA-induced release of cerebral monoamines. Science, 170, 76-77.
    • (1970) Science , vol.170 , pp. 76-77
    • Ng, K.Y.1    Chase, T.N.2    Colburn, R.W.3    Kopin, I.J.4
  • 49
    • 0034966490 scopus 로고    scopus 로고
    • Reponse to levodopa treatment in dopa-responsive dystonia
    • Nutt, J.G. & Nygaard, T.G. (2011) Reponse to levodopa treatment in dopa-responsive dystonia. Arch. Neurol., 58, 905-910.
    • (2011) Arch. Neurol. , vol.58 , pp. 905-910
    • Nutt, J.G.1    Nygaard, T.G.2
  • 50
    • 0033696872 scopus 로고    scopus 로고
    • Continuous dopamine receptor stimulation in advanced Parkinson's disease
    • Nutt, J.G., Obeso, J.A. & Stocchi, F. (2000) Continuous dopamine receptor stimulation in advanced Parkinson's disease. Trends Neurosci., 23, S109-S115.
    • (2000) Trends Neurosci. , vol.23
    • Nutt, J.G.1    Obeso, J.A.2    Stocchi, F.3
  • 51
    • 0029064091 scopus 로고
    • Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test
    • Olsson, M., Nikkhah, G., Bentlage, C. & Björklund, A. (1995) Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test. J. Neurosci., 15, 3863-3875.
    • (1995) J. Neurosci. , vol.15 , pp. 3863-3875
    • Olsson, M.1    Nikkhah, G.2    Bentlage, C.3    Björklund, A.4
  • 52
    • 0031456987 scopus 로고    scopus 로고
    • Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites
    • Owens, M.J., Morgan, W.N., Plott, S.J. & Nemeroff, C.B. (1997) Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J. Pharmacol. Exp. Ther., 283, 1305-1322.
    • (1997) J. Pharmacol. Exp. Ther. , vol.283 , pp. 1305-1322
    • Owens, M.J.1    Morgan, W.N.2    Plott, S.J.3    Nemeroff, C.B.4
  • 53
    • 80955180002 scopus 로고    scopus 로고
    • Induction and expression of abnormal involuntary movements is related to the duration of dopaminergic stimulation in 6-OHDA-lesioned rats
    • Papathanou, M., Rose, S., McCreary, A. & Jenner, P. (2011) Induction and expression of abnormal involuntary movements is related to the duration of dopaminergic stimulation in 6-OHDA-lesioned rats. Eur. J. Neurosci., 33, 2247-2254.
    • (2011) Eur. J. Neurosci. , vol.33 , pp. 2247-2254
    • Papathanou, M.1    Rose, S.2    McCreary, A.3    Jenner, P.4
  • 55
    • 0026569201 scopus 로고
    • Effect of fluoxetine on serotonin and dopamine concentration in microdialysis fluid from rat striatum
    • Perry, K.W. & Fuller, R.W. (1992) Effect of fluoxetine on serotonin and dopamine concentration in microdialysis fluid from rat striatum. Life Sci., 50, 1683-1690.
    • (1992) Life Sci. , vol.50 , pp. 1683-1690
    • Perry, K.W.1    Fuller, R.W.2
  • 56
    • 34548822469 scopus 로고    scopus 로고
    • Evaluation of levodopa dose and magnitude of dopamine depletion as risk factors for levodopa-induced dyskinesia in a rat model of Parkinson's disease
    • Putterman, D.B., Munhall, A.C., Kozell, L.B., Belknap, J.K. & Johnson, S.W. (2007) Evaluation of levodopa dose and magnitude of dopamine depletion as risk factors for levodopa-induced dyskinesia in a rat model of Parkinson's disease. J. Pharmacol. Exp. Ther., 323, 277-284.
    • (2007) J. Pharmacol. Exp. Ther. , vol.323 , pp. 277-284
    • Putterman, D.B.1    Munhall, A.C.2    Kozell, L.B.3    Belknap, J.K.4    Johnson, S.W.5
  • 57
    • 0036176781 scopus 로고    scopus 로고
    • The SSRI, citalopram, improves bradykinesia in patients with Parkinson's disease treated with L-dopa
    • Rampello, L., Chiechio, S., Raffaele, R., Vecchio, I. & Nicoletti, F. (2002) The SSRI, citalopram, improves bradykinesia in patients with Parkinson's disease treated with L-dopa. Clin. Neuropharmacol., 25, 21-24.
    • (2002) Clin. Neuropharmacol. , vol.25 , pp. 21-24
    • Rampello, L.1    Chiechio, S.2    Raffaele, R.3    Vecchio, I.4    Nicoletti, F.5
  • 58
    • 0030664249 scopus 로고    scopus 로고
    • A survey of antidepressant drug use in Parkinson's disease. Parkinson Study Group
    • Richard, I.H. & Kurlan, R. (1997) A survey of antidepressant drug use in Parkinson's disease. Parkinson Study Group. Neurology, 49, 1168-1170.
    • (1997) Neurology , vol.49 , pp. 1168-1170
    • Richard, I.H.1    Kurlan, R.2
  • 60
    • 0018421663 scopus 로고
    • Excessive bracing reactions and their control by atropine and L-DOPA in an animal analog of Parkinsonism
    • Schallert, T., De Ryck, M., Whishaw, I.Q., Ramirez, V.D. & Teitelbaum, P. (1979) Excessive bracing reactions and their control by atropine and L-DOPA in an animal analog of Parkinsonism. Exp. Neurol., 64, 33-43.
    • (1979) Exp. Neurol. , vol.64 , pp. 33-43
    • Schallert, T.1    De Ryck, M.2    Whishaw, I.Q.3    Ramirez, V.D.4    Teitelbaum, P.5
  • 61
    • 84856101280 scopus 로고    scopus 로고
    • Parkinson's disease therapeutics: new developments and challenges since the introduction of levodopa
    • Smith, Y., Wichmann, T., Factor, S.A. & DeLong, M.R. (2012) Parkinson's disease therapeutics: new developments and challenges since the introduction of levodopa. Neuropsychopharmacology, 37, 213-246.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 213-246
    • Smith, Y.1    Wichmann, T.2    Factor, S.A.3    DeLong, M.R.4
  • 62
    • 0027448043 scopus 로고
    • Increase of Parkinson disability after fluoxetine medication
    • Steur, E.N. (1993) Increase of Parkinson disability after fluoxetine medication. Neurology, 43, 211-213.
    • (1993) Neurology , vol.43 , pp. 211-213
    • Steur, E.N.1
  • 64
    • 0031565115 scopus 로고    scopus 로고
    • Pharmacological profile of antidepressants and related compounds at human monoamine transporters
    • Tatsumi, M., Groshan, K., Blakely, R.D. & Richelson, E. (1997) Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur. J. Pharmacol., 340, 249-258.
    • (1997) Eur. J. Pharmacol. , vol.340 , pp. 249-258
    • Tatsumi, M.1    Groshan, K.2    Blakely, R.D.3    Richelson, E.4
  • 66
    • 0343329775 scopus 로고    scopus 로고
    • Apomorphine responses in Parkinson's disease and the pathogenesis of motor complications
    • Verhagen Metman, L., Locatelli, E.R., Bravi, D., Mouradian, M.M. & Chase, T.N. (1997) Apomorphine responses in Parkinson's disease and the pathogenesis of motor complications. Neurology, 48, 369-372.
    • (1997) Neurology , vol.48 , pp. 369-372
    • Verhagen Metman, L.1    Locatelli, E.R.2    Bravi, D.3    Mouradian, M.M.4    Chase, T.N.5
  • 68
    • 0035826913 scopus 로고    scopus 로고
    • Fluoxetine reduces l-DOPA-derived extracellular DA in the 6-OHDA-lesioned rat striatum
    • Yamato, H., Kannari, K., Shen, H., Suda, T. & Matsunaga, M. (2001) Fluoxetine reduces l-DOPA-derived extracellular DA in the 6-OHDA-lesioned rat striatum. NeuroReport, 12, 1123-1126.
    • (2001) NeuroReport , vol.12 , pp. 1123-1126
    • Yamato, H.1    Kannari, K.2    Shen, H.3    Suda, T.4    Matsunaga, M.5
  • 69
    • 41149134856 scopus 로고    scopus 로고
    • Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in l-DOPA treatment of an animal model of Parkinsonism
    • Zhang, X., Andren, P.E., Greengard, P. & Svenningsson, P. (2008) Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in l-DOPA treatment of an animal model of Parkinsonism. Proc. Natl. Acad. Sci. USA, 105, 2163-2168.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 2163-2168
    • Zhang, X.1    Andren, P.E.2    Greengard, P.3    Svenningsson, P.4
  • 70
    • 0021235482 scopus 로고
    • Neurochemical compensation after nigrostriatal bundle injury in an animal model of preclinical parkinsonism
    • Zigmond, M.J., Acheson, A.L., Stachowiak, M.K. & Stricker, E.M. (1984) Neurochemical compensation after nigrostriatal bundle injury in an animal model of preclinical parkinsonism. Arch. Neurol., 41, 856-861.
    • (1984) Arch. Neurol. , vol.41 , pp. 856-861
    • Zigmond, M.J.1    Acheson, A.L.2    Stachowiak, M.K.3    Stricker, E.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.