Replacing semicircular canal function with a vestibular implant

Current Opinion in Otolaryngology and Head and Neck Surgery

Volumn 20, Issue 5, 2012, Pages 386-392

  Merfeld, Daniel M ^a,b   Lewis, Richard F ^a,b  

^a MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

neural implant; neural prosthesis; prosthesis; sensory replacement; spatial orientation; VOR

Indexed keywords

ADAPTATION; CALIBRATION; ELECTRODE; ELECTROSTIMULATION; HEARING; HUMAN; MIDDLE EAR IMPLANT; NONHUMAN; PRIORITY JOURNAL; REVIEW; RHESUS MONKEY; SEMICIRCULAR CANAL; SOCIAL STATUS; SURGICAL TECHNIQUE; TREATMENT OUTCOME; VESTIBULAR DISORDER; VESTIBULOOCULAR REFLEX;

ANIMALS; DISABILITY EVALUATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMPLANTABLE NEUROSTIMULATORS; MACACA MULATTA; MALE; PROSTHESIS IMPLANTATION; RISK ASSESSMENT; SEMICIRCULAR CANALS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; VESTIBULAR DISEASES;

EID: 84866412857     PISSN: 10689508     EISSN: 15316998     Source Type: Journal    
DOI: 10.1097/MOO.0b013e328357630f     Document Type: Review

References (46)

1. Guinand N, Boselie F, Guyot JP, Kingma H. Quality of life of patients with bilateral vestibulopathy. Ann Otol Rhinol Laryngol 2012; 121.
2. Merfeld D, Rabbitt R. Vestibular prosthetics. In: Horch K, Dhillon G, editors. Neuroprosthetics: Theory and practice. Singapore: World Scientific Publishing; 2004. pp. 1115-1145.
3. Purkynje J. Beitrge zur naheren Kenntnis des Schwindels mit heautognostischen Daten. Med Jahrb k u Osterstaates 1820; 6:79-125.
4. Hitzig E. Ueber die beim Galvanisieren des Kopfes entstehenden Stö rungen der Muskelinnernation und der Vorstellungen vom Verhalten im Raume [About perturbations of muscle innervation and imaginations of behavior in space during head galvanisation]. Reichert u du Bois-Reymond's Arch 1871; 716- 770.
5. Mach E. Fundamentals of the theory of movement perception. New York: Kluwer Academic/Plenum Publishers; 1875.
6. Breuer J. Ueber die Funktion der Bogengänge des Ohrlabyrinths [About the functions of the semicircular canals of the ear labyrinth].Med Jahrbuü cher 2nd series 1874; 4:72-124.
7. Ewald J. Physiologische Untersuchungen ueber das Endorgan des Nervus octavus. Wiesbaden: Bergmann; 1892.
8. Cohen B, Suzuki J, Bender M. Eye movements from semicircular canal nerve stimulation in the cat. Ann Otol Rhinol Laryngol 1964; 73:153-169.
9. Suzuki JI, Cohen B. Head, eye, body and limb movements from semicircular canal nerves. Exp Neurol 1964; 10:393-405.
10. Cohen B, Suzuki J, Bender M. Nystagmus induced by electrical stimulation of the ampullary nerves. Acta Otolaryngol 1965; 60:422-436.
11. Suzuki J, Cohen B. Integration of semicircular canal activity. J Neurophysiol 1966; 29:981-995.
12. Suzuki J, Goto K, Tokumasu K, Cohen B. Implantation of electrodes near individual vestibular nerve branches in mammals. Ann Otolaryngol Rhinol Laryngol 1969; 78:815-826.
13. Lewis RF, Gong W, Ramsey M, et al. Vestibular adaptation studied with a prosthetic semicircular canal. J Vestib Res 2002; 12:87-94.
14. Merfeld DM, Gong W, Morrissey J, et al. Acclimation to chronic constant-rate peripheral stimulation provided by a vestibular prosthesis. IEEE Trans Biomed Eng 2006; 53:2362-2372.
15. Merfeld DM, Haburcakova C, Gong W, Lewis RF. Chronic vestibulo-ocular reflexes evoked by a vestibular prosthesis. IEEE Trans Biomed Eng 2007; 54 (6 Pt 1):1005-1015.
16. Lewis RF, Haburcakova C, Gong W, et al. Vestibuloocular reflex adaptation nvestigated with chronic motion-modulated electrical stimulation of semicircular canal fferents. J Neurophysiol 2010; 103:1066-1079.
17. Gong W, Merfeld D. A prototype neural semicircular canal prosthesis using patterned electrical stimulation. Ann Biomed Eng 2000; 28:572-581.
18. Gong W, Merfeld D. System design and performance of a unilateral semicircular canal prosthesis. IEEE Trans Biomed Eng 2002; 49:175-181.
19. Wall C 3rd, Kos MI, Guyot JP. Eye movements in response to electric stimulation of the human posterior ampullary nerve. Ann Otol Rhinol Laryngol 2007; 116:369-374.
20. Van de Berg R, Guinand N, Stokroos RJ, et al. The vestibular implant: quo vadis? Front Neurol 2011; 2:47. PMCID: 3181464.
21. Fridman GY, Della Santina C. Progress toward development of a multichannel vestibular prosthesis for treatment of bilateral vestibular deficiency. Anat Rec (in press).
22. Rubinstein JT, Bierer S, Kaneko C, et al. Implantation of the semicircular canals with preservation of hearing and rotational sensitivity: A vestibular neurostimulator suitable for clinical research. Otol Neurotol 2012; 33:789-796.
23. Golub J, Phillips JO, Rubinstein JT. Chapter 5 Vestibular implants. In: Zeng F-G, Fay R, Popper A, editors. Auditory prostheses: New horizons. New York: Springer Verlag; 2012. pp. 109-133.
24. Guyot J, Gay A, Kos M, Pelizzone M. Ethical, anatomical and physiological issues in developing vestibular implants for human use. J Vestibul Res (in press).
25. Poppendieck W, Hoffmann KP, Merfeld D, et al. Ethical issues in the development of a vestibular prosthesis. Conf Proc IEEE Eng Med Biol Soc 2011; 2011:2265-2268.
26. Van de Berg R, Guinand N, Guyot JP, et al. The modified ampullar approach for vestibular implant surgery: feasibility and its first application in a human with a long-term vestibular loss. Front Neurol 2012; 3:18. PMCID: 3282298.
27. Guyot JP, Sigrist A, Pelizzone M, Kos MI. Adaptation to steady-state electrical stimulation of the vestibular system in humans. Ann Otol Rhinol Laryngol 2011; 120:143-149.
28. Guyot JP, Sigrist A, Pelizzone M, et al. Eye movements in response to electrical stimulation of the lateral and superior ampullary nerves. Ann Otol Rhinol Laryngol 2011; 120:81-87.
29. Dai C, Fridman GY, Della Santina CC. Effects of vestibular prosthesis electrode implantation and stimulation on hearing in rhesus monkeys. Hear Res 2011; 277:204-210; PMCID: 3081362.
30. Bierer SM, Ling L, Nie K, et al. Auditory outcomes following implantation and electrical stimulation of the semicircular canals. Hear Res 2012; 287:51-56.
31. Coordes A, Basta D, Gotze R, et al. Sound-induced vertigo after cochlear implantation. Otol Neurotol 2012; 33:335-342.
32. Saginaw MA, Gong W, Haburcakova C, Merfeld DM. Attenuation of eye movements evoked by a vestibular implant at the frequency of the baseline pulse rate. IEEE Trans Biomed Eng 2011; 58:2732-2739.
33. Merfeld D, inventor Massachusetts Eye and Ear Infirmary, assignee. Sensor signal alignment. USA patent 7,454,246. 2008.
34. Fridman GY, Davidovics NS, Dai C, et al. Vestibulo-ocular reflex responses to a multichannel vestibular prosthesis incorporating a 3D coordinate transformation for correction of misalignment. J Assoc Res Otolaryngol 2010; 11:367-381; PMCID: 2914246.
35. Merfeld D, inventor Massachusetts Eye and Ear Infirmary, assignee. Sensor signal alignment. USA patent 7,912,542. 2011.
36. Digiovanna J, Carpaneto J, Micera S, Merfeld DM. Alignment of angular velocity sensors for a vestibular prosthesis. J Neuroeng Rehabil 2012; 9:14.
37. Davidovics NS, Fridman GY, Chiang B, Della Santina CC. Effects of biphasic current pulse frequency, amplitude, duration, and interphase gap on eye movement responses to prosthetic electrical stimulation of the vestibular nerve. IEEE Trans Neural Syst Rehabil Eng 2011; 19:84-94; PMCID: 3110786.
38. Davidovics NS, Fridman GY, Della Santina CC. Co-modulation of stimulus rate and current from elevated baselines expands head motion encoding range of the vestibular prosthesis. Exp Brain Res 2012; 218:389-400.
39. Chiang B, Fridman GY, Dai C, et al. Design and performance of a multichannel vestibular prosthesis that restores semicircular canal sensation in rhesus monkey. IEEE Trans Neural Syst Rehabil Eng 2011; 19:588-598.
40. Hayden R, Sawyer S, Frey E, et al. Virtual labyrinth model of vestibular afferent excitation via implanted electrodes: Validation and application to design of a multichannel vestibular prosthesis. Exp Brain Res 2011; 210:623-640; PMCID: 3270068.
41. Jiang D, Demosthenous A, Liu X, et al. Astimulator ASIC featuring versatile management for vestibular prostheses. IEEE Trans Biomed Circuits Systems 2011; 5:147-159.
42. Dai C, Fridman GY, Davidovics NS, et al. Restoration of 3D vestibular sensation in rhesus monkeys using a multichannel vestibular prosthesis. Hear Res 2011; 281:74-83.
43. Dai C, Fridman GY, Chiang B, et al. Cross-axis adaptation improves 3D vestibulo-ocular reflex alignment during chronic stimulation via a headmounted multichannel vestibular prosthesis. Exp Brain Res 2011; 210: 595-606; PMCID: 3270066.
44. Sun DQ, Rahman MA, Fridman G, et al. Chronic stimulation of the semicircular canals using a multichannel vestibular prosthesis: Effects on locomotion and angular vestibulo-ocular reflex in chinchillas. Conf Proc IEEE Eng Med Biol Soc 2011; 2011:3519-3523; PMCID: 3307049.
45. Lewis R, Haburcakova C, Gong W, et al. Spatial and temporal characteristics of eye movements produced by electrical stimulation of semicircular canal afferents. J Neurophysiol (in press).
46. Lewis RF, Haburcakova C, Gong W, et al. Vestibular prosthesis tested in rhesus monkeys. Conf Proc IEEE Eng Med Biol Soc 2011; 2011:2277- 2279.