Attenuation of eye movements evoked by a vestibular implant at the frequency of the baseline pulse rate

IEEE Transactions on Biomedical Engineering

Volumn 58, Issue 10 PART 1, 2011, Pages 2732-2739

  Saginaw, Michael A ^a   Gong, Wangsong ^b,c   Haburcakova, Csilla ^b,c   Merfeld, Daniel M ^b,c  

^a MATHWORKS INC   (United States)

^b MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Biomedical engineering; prosthetics; translational medicine; vestibuloocular reflex (VOR)

Indexed keywords

CONSTANT RATE; ELECTRIC STIMULATION; ELECTRICAL PROSTHESIS; ELECTRICAL STIMULATIONS; GUINEA PIGS; NEURAL RESPONSE; PEAK VELOCITIES; PULSE RATE; SEMICIRCULAR CANAL; TIME CONSTANTS; TRANSLATIONAL MEDICINE; VESTIBULO-OCULAR REFLEX;

BIOMEDICAL ENGINEERING; ELECTROPHYSIOLOGY; ELECTROTHERAPEUTICS; MEDICINE; PROSTHETICS;

EYE MOVEMENTS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLURRED VISION; CONTROLLED STUDY; ELECTROSTIMULATION; EYE MOVEMENT; GUINEA PIG; IMPLANT; NERVE POTENTIAL; NONHUMAN; PULSE RATE; SEMICIRCULAR CANAL; VERTIGO; VESTIBULAR DISORDER; VESTIBULAR EVOKED POTENTIAL; VESTIBULOOCULAR REFLEX; VISUAL IMPAIRMENT;

ANIMALS; BIOMEDICAL ENGINEERING; COCHLEAR IMPLANTS; EYE MOVEMENTS; GUINEA PIGS; HAIR CELLS, VESTIBULAR; MALE; REFLEX, VESTIBULO-OCULAR; VISION DISORDERS;

EID: 80053208872     PISSN: 00189294     EISSN: 15582531     Source Type: Journal    
DOI: 10.1109/TBME.2010.2095850     Document Type: Article

References (34)

1. W. Gong and D. M. Merfeld, "Prototype neural semicircular canal prosthesis using patterned electrical stimulation," Ann. Biomed. Eng., vol. 28, no. 5, pp. 572-581, May 2000.
2. W. Gong and D.M.Merfeld, "System design and performance of a unilateral horizontal semicircular canal prosthesis," IEEE Trans. Biomed. Eng., vol. 49, no. 2, pp. 175-181, Feb. 2002.
3. C.Wall, III, D. M. Merfeld, S.D. Rauch, and F. O. Black, "Vestibular prostheses: The engineering and biomedical issues," J. Vestib. Res., vol. 12, pp. 95-113, 2002.
4. R. F. Lewis,W. Gong, M. Ramsey, L.Minor, R. Boyle, and D.M.Merfeld, "Vestibular adaptation studied with a prosthetic semicircular canal," J. Vestib. Res., vol. 12, no. 2/3, pp. 87-94, 2002/2003.
5. D. Merfeld and R. Rabbitt, "Vestibular prosthetics," in Neuroprosthetics: Theory and Practice, K. Horch and G. Dhillon, Eds. Singapore: World Scientific Publishing, 2004, pp. 1115-1145.
6. D. M. Merfeld, W. Gong, J. Morrissey, M. A. Saginaw, C. Haburcakova, and R. F. Lewis, "Acclimation to chronic constant-rate peripheral stimulation provided by a vestibular prosthesis," IEEE Trans. Biomed. Eng., vol. 53, no. 11, pp. 2362-2372, Nov. 2006.
7. D. M. Merfeld, C. Haburcakova, W. Gong, and R. F. Lewis, "Chronic vestibulo-ocular reflexes evoked by a vestibular prosthesis," IEEE Trans. Biomed. Eng., vol. 54, no. 6, pp. 1005-1015, Jun. 2007.
8. W. Gong, C. Haburcakova, and D. M. Merfeld, "Vestibulo-ocular responses evoked via bilateral electrical stimulation of the lateral semicircular canals," IEEE Trans. Biomed. Eng., vol. 55, no. 11, pp. 2608-2619, Nov. 2008.
9. R. F. Lewis, C. Haburcakova, W. Gong, C. Makary, and D. M. Merfeld, "Vestibulo-ocular reflex adaptation investigated with chronic motion-modulated electrical stimulation of semicircular canal afferents," J. Neurophysiol., vol. 103, no. 2, pp. 1066-1079, 2010.
10. J. T. Rubinstein and C. C. Della Santina, "Development of a biophysical model for vestibular prosthesis research," J. Vestib. Res., vol. 12, pp. 69- 76, 2002.
11. C. C. Della Santina, A. A. Migliaccio, and A. H. Patel, "A multichannel semicircular canal neural prosthesis using electrical stimulation to restore 3-d vestibular sensation," IEEE Trans. Biomed. Eng., vol. 54, no. 6, pp. 1016-1030, Jun. 2007.
12. S. Tang, T.-A. N.Melvin, and C. C. Della Santina, "Effects of semicircular canal electrode implantation on hearing in chinchillas," Acta Otolaryngol, vol. 129, pp. 481-486, May 2009.
13. A. M. Shkel and F. G. Zeng, "An electronic prosthesis mimicking the dynamic vestibular function," Audiol Neurootol, vol. 11, pp. 113-22, 2006.
14. Y. Agrawal, J. P. Carey, C. C. Della Santina, M. C. Schubert, and L. B. Minor, "Disorders of balance and vestibular function in U.S. adults: Data from the national health and nutrition examination survey, 2001- 2004," Arch. Intern. Med., vol. 169, no. 10, pp. 938-944, May 2009.
15. N. Y. Kiang and E. C. Moxon, "Physiological considerations in artificial stimulation of the inner ear," Ann. Otol. Rhinol. Laryngol., vol. 81, no. 5, pp. 714-730, Oct. 1972.
16. M. A. Saginaw, "Eye movement studies with a vestibular prosthesis," Ph.D. dissertation, Dept. Elect. Eng. Comp. Sci. Massachusetts Institute of Technology, Cambridge, MA, 2010.
17. S. J. Judge, B. J. Richmond, and F. C. Chu, "Implantation of magnetic search coils for measurement of eye position: An improved method," Vis. Res., vol. 20, no. 6, pp. 535-538, 1980.
18. D.M.Lasker,D.D. Backous,A. Lysakowski,G.L.Davis, andL. B.Minor, "Horizontal vestibuloocular reflex evoked by high-acceleration rotations in the squirrel monkey-Part II: Responses after canal plugging," J. Neurophysiol., vol. 82, no. 3, pp. 1271-1285, 1999.
19. G. D. Paige, "Vestibuloocular reflex and its interactions with visual following mechanisms in the squirrel monkey-Part II: Response characteristics and plasticity following unilateral inactivation of horizontal canal," J. Neurophysiol., vol. 49, no. 1, pp. 152-168, 1983.
20. R. F. Lewis, C. Haburcakova, W. Gong, C. Makary, and D. M. Merfeld, "Vestibuloocular reflex adaptation investigated with chronic motionmodulated electrical stimulation of semicircular canal afferents," J. Neurophysiol., vol. 103, no. 2, pp. 1066-1079, 2010.
21. T. L. Babb, H. V. Soper, J. P. Lieb, W. J. Brown, C. A. Ottino, and P. H. Crandall, "Electrophysiological studies of long-term electrical stimulation of the cerebellum inmonkeys," J. Neurosurg., vol. 47, pp. 353-365, 1977.
22. R. K. Shepherd, B. K.-H. Franz, and G. M. Clark, "The biocompatibility and safety of cochlear prostheses," in Cochlear Prostheses, G. M. Clark, Y.T. Tong, and J. F. Patrick, Eds. Edinburgh: Churchill Livingstone, 1990, pp. 69-98.
23. L. S. Robblee and T. L. Rose, "Electrochemical guidelines for selection of protocols and electrode materials for neural stimulation," in Neural Prostheses Fundamental Studies, W. F. Agnew and D. B. McCreery, Eds. Englewood Cliffs, NJ: Prentice Hall, 1990, pp. 25-66.
24. D. A. Robinson, "A method of measuring eye movement using a scleral search coil in a magnetic field," IEEE Trans. Biomed. Electron., vol. 10, no. 4, pp. 137-145, Oct. 1963.
25. M. A. Saginaw, W. Gong, C. Haburcakova, and D. M. Merfeld, "Eye movements above 100 Hz studied with vestibular electrical prosthesis," presented at the 2007 Neuroscience, San Diego, CA.
26. S. Martinez-Conde, S. L.Macknik, andD.H.Hubel, "The role of fixational eyemovements in visual perception," Nat. Rev. Neurosci., vol. 5, pp. 229- 240, Mar. 2004.
27. M. Yanoff and J. S. Duker, Ed., "Visible light," in Ophthalmology-Part 2: Optics and Refraction, 2nd ed. St. Louis: Mosby, 2004, ch. 4, p. 33.
28. M. Yanoff and J. S. Duker, Ed., "Optics of the normal eye," in Ophthalmology-Part 2: Optics and Refraction, 2nd ed., St. LouisMosby, 2004, ch. 9, p. 61.
29. M. Yanoff and J. S. Duker, Ed., "Optics of the normal eye," in Ophthalmology-Part 2: Optics and Refraction, 2nd ed. St. Louis: Mosby, ibid, p. 66.
30. R. J. Leigh and D. S. Zee, "Smooth pursuit and visual fixation," in The Neurology of Eye Movements-Part 1: The Properties and Neural Substrate of Eye Movements. New York: Oxford Univ. Press, 2006, ch. 4, p. 189.
31. D. M. Merfeld, A. Priesol, D. Lee, and R. F. Lewis, "Potential solutions to several vestibular challenges facing clinicians," J. Vestib. Res., vol. 20, no. 1-2, pp. 71-77, Jan. 2010.
32. E. Kandel, J. Schwartz, and T. Jessell, "Learning and Memory," in Principles of Neural Science-Part IX: Language, Thought, Mood, Learning, and Memory, 4th ed. New York: McGraw-Hill Medical, 2000, ch. 62.
33. E. Kandel, J. Schwartz, and T. Jessell, "Posture," in Principles of Neural Science-Part IV:Movement, 4th ed. New York:McGraw-Hill Medical, 2000, ch. 41, p. 825.
34. J. H. Courjon, W. Precht, and D. W. Sirkin, "Vestibular nerve and nuclei unit responses and eye movement responses to repetitive galvanic stimulation of the labyrinth in the rat," Exp. Brain Res., vol. 66, no. 1, pp. 41-48, Mar. 1987.