Troponin i measured with a high sensitivity immunoassay is significantly increased after a half marathon run

Scandinavian Journal of Clinical and Laboratory Investigation

Volumn 72, Issue 6, 2012, Pages 467-470

  Lippi, Giuseppe ^a   Schena, Federico ^b   Dipalo, Mariella ^a   Montagnana, Martina ^b   Salvagno, Gian L ^b   Aloe, Rosalia ^a   Guidi, Gian C ^b  

^a UNIVERSITY HOSPITAL OF PARMA   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

Cardiac biomarkers; Marathon; Physical exercise; Sport; Troponin

Indexed keywords

TROPONIN I;

ADULT; ARTICLE; CONTROLLED STUDY; EXERCISE INTENSITY; HIGH SENSITIVITY IMMUNOASSAY; HUMAN; HUMAN EXPERIMENT; IMMUNOASSAY; MALE; MARATHON RUNNER; NORMAL HUMAN; PRIORITY JOURNAL;

ADULT; ATHLETES; HUMANS; IMMUNOASSAY; KINETICS; MALE; MIDDLE AGED; RUNNING; SENSITIVITY AND SPECIFICITY; TROPONIN I;

EID: 84866410337     PISSN: 00365513     EISSN: 15027686     Source Type: Journal    
DOI: 10.3109/00365513.2012.697575     Document Type: Article

References (25)

1. Colberg SR, Sigal RJ, Fernhall B, Regensteiner JG, Blissmer BJ, Rubin RR, Chasan-Taber L, Albright AL, Braun B. American College of Sports Medicine; American Diabetes Association. Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement executive summary. Diabetes Care 2010:33;2692-6.
2. Kushi LH, Byers T, Doyle C, Bandera EV, McCullough M, McTiernan A, Gansler T, Andrews KS, Thun MJ. American Cancer Society 2006 Nutrition and Physical Activity Guidelines Advisory Committee. American Cancer Society Guidelines on Nutrition and Physical Activity for cancer prevention: reducing the risk of cancer with healthy food choices and physical activity. CA Cancer J Clin 2006;56:254-81.
3. Nelson ME, Rejeski WJ, Blair SN, Duncan PW, Judge JO, King AC, Macera CA, Castaneda-Sceppa C. Physical activity and public health in older adults: recommendation from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc 2007; 39:1435-45.
4. O'Donovan G, Blazevich AJ, Boreham C, Cooper AR, Crank H, Ekelund U, Fox KR, Gately P, Giles-Corti B, Gill JM, Hamer M, McDermott I, Murphy M, Mutrie N, Reilly JJ, Saxton JM, Stamatakis E. The ABC of Physical Activity for Health: a consensus statement from the British Association of Sport and Exercise Sciences. J Sports Sci 2010;28:573-91.
5. Ruiz JR, Morán M, Arenas J, Lucia A. Strenuous endurance exercise improves life expectancy: it's in our genes. Br J Sports Med 2011;45:159-61.
6. Sanchis-Gomar F, Olaso-Gonzalez G, Corella D, Gomez-Cabrera MC, Vina J. Increased average longevity among the 'Tour de France' cyclists. Int J Sports Med 2011;32:644-7.
7. Neilan TG, Januzzi JL, Lee-Lewandrowski E, Ton-Nu TT, Yoerger DM, Jassal DS, Lewandrowski KB, Siegel AJ, Marshall JE, Douglas PS, Lawlor D, Picard MH, Wood MJ. Myocardial injury and ventricular dysfunction related to training levels among nonelite participants in the Boston marathon. Circulation 2006;114:2325-33.
8. Neilan TG, Yoerger DM, Douglas PS, Marshall JE, Halpern EF, Lawlor D, Picard MH, Wood MJ. Persistent and reversible cardiac dysfunction among amateur marathon runners. Eur Heart J 2006;27:1079-84.
9. George KP, Naylor LH, Whyte GP, Shave RE, Oxborough D, Green DJ. Diastolic function in healthy humans: noninvasive assessment and the impact of acute and chronic exercise. Eur J Appl Physiol 2010;108:1-14.
10. O'Hanlon R, Wilson M, Wage R, Smith G, Alpendurada FD, Wong J, Dahl A, Oxborough D, Godfrey R, Sharma S, Roughton M, George K, Pennell DJ, Whyte G, Prasad SK. Troponin release following endurance exercise: is infl ammation the cause? A cardiovascular magnetic resonance study. J Cardiovasc Magn Reson 2010;12:38.
11. Trivax JE, Franklin BA, Goldstein JA, Chinnaiyan KM, Gallagher MJ, deJong AT, Colar JM, Haines DE, McCullough PA. Acute cardiac effects of marathon running. J Appl Physiol 2010;108:1148-53.
12. Pelliccia A, Kinoshita N, Pisicchio C, Quattrini F, Dipaolo FM, Ciardo R, Di Giacinto B, Guerra E, De Blasiis E, Casasco M, Culasso F, Maron BJ. Long-term clinical consequences of intense, uninterrupted endurance training in Olympic athletes. J Am Coll Cardiol 2010;55:1619-25.
13. Lippi G, Cervellin G, Banfi G, Plebani M. Cardiac troponins and physical exercise. It's time to make a point. Biochem Med 2011;21:55-64.
14. Legaz-Arrese A, George K, Carranza-García LE, Munguía- Izquierdo D, Moros-García T, Serrano-Ostáriz E. The impact of exercise intensity on the release of cardiac biomarkers in marathon runners. Eur J Appl Physiol 2011; 111:2961-7.
15. Mingels A, Jacobs L, Michielsen E, Swaanenburg J, Wodzig W, van Dieijen-Visser M. Reference population and marathon runner sera assessed by highly sensitive cardiac troponin T and commercial cardiac troponin T and I assays. Clin Chem 2009;55:101-8.
16. Saravia SG, Knebel F, Schroeckh S, Ziebig R, Lun A, Weimann A, Haberland A, Borges AC, Schimke I. Cardiac troponin T release and infl ammation demonstrated in marathon runners. Clin Lab 2010;56:51-8.
17. Scherr J, Braun S, Schuster T, Hartmann C, Moehlenkamp S, Wolfarth B, Pressler A, Halle M. 72-h kinetics of highsensitive troponin T and infl ammatory markers after marathon. Med Sci Sports Exerc 2011;43:1819-27.
18. Giannitsis E, Roth HJ, Leithäuser RM, Scherhag J, Beneke R, Katus HA. New high sensitivity assay used to measure cardiac troponin T concentration changes during a continuous 216-km marathon. Clin Chem 2009;55:590-2.
19. Zaninotto M, Mion MM, Novello E, Moretti M, Delprete E, Rocchi MB, Sisti D, Plebani M. Precision performance at low levels and 99th percentile concentration of the Access AccuTnl assay on two different platforms. Clin Chem Lab Med 2009;47:367-71.
20. Kavsak PA, MacRae AR, Yerna MJ, Jaffe AS. Analytic and clinical utility of a next-generation, highly sensitive cardiac troponin I assay for early detection of myocardial injury. Clin Chem 2009;55:573-7.
21. La Gerche A, Prior DL, Heidbüchel H. Strenuous endurance exercise: is more better for everyone? Our genes won't tell us. Br J Sports Med 2011;45:162-4.
22. Wagner KH, Reichhold S, Neubauer O. Impact of endurance and ultraendurance exercise on DNA damage. Ann NY Acad Sci 2011;1229:115-23.
23. Lippi G, Impellizzeri F, Salvagno GL, Mion M, Zaninotto M, Cervellin G, Guidi GC, Schena F, Plebani M. Kinetics of highly sensitive troponin I and T after eccentric exercise. Clin Chem Lab Med 2010;48:1677-9.
24. Lippi G, Tessitore N, Montagnana M, Salvagno GL, Lupo A, Guidi GC. Infl uence of sampling time and ultrafi ltration coeffi cient of the dialysis membrane on cardiac troponin I and T. Arch Pathol Lab Med 2008;132:72-6.
25. Lippi G, Banfi G. Exercise-related increase of cardiac troponin release in sports: an apparent paradox fi nally elucidated? Clin Chim Acta 2010;411:610-1.