Interactions between the PDZ domains of Bazooka (Par-3) and phosphatidic acid: In vitro characterization and role in epithelial development

Molecular Biology of the Cell

Volumn 23, Issue 18, 2012, Pages 3743-3753

  Yu, Cao Guo ^a   Harris, Tony J C ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DIACYLGLYCEROL KINASE; LIPOSOME; MEMBRANE LIPID; PHOSPHATIDIC ACID; PROTEINASE ACTIVATED RECEPTOR 3;

ARTICLE; BAZOOKA GENE; CELL MEMBRANE; CONTROLLED STUDY; EMBRYO; EPITHELIUM CELL; GENE; IN VITRO STUDY; MUTATION; NERVE CELL CHARACTERISTICS AND FUNCTIONS; NONHUMAN; PDZ DOMAIN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL POLARITY; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; EPITHELIUM; FEMALE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOSOMES; MALE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PDZ DOMAINS; PHOSPHATIDIC ACIDS; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84866406402     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E12-03-0196     Document Type: Article

References (35)

1. Antonescu CN, Danuser G, Schmid SL (2010). Phosphatidic acid plays a regulatory role in clathrin-mediated endocytosis. Mol Biol Cell 21, 2944-2952.
2. Benton R, St Johnston D (2003). A conserved oligomerization domain in drosophila Bazooka/PAR-3 is important for apical localization and epithelial polarity. Curr Biol 13, 1330-1334. (Pubitemid 36953307)
3. Chianale F et al. (2010). Diacylglycerol kinase alpha mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI. Proc Natl Acad Sci USA 107, 4182-4187.
4. Fang Y, Vilella-Bach M, Bachmann R, Flanigan A, Chen J (2001). Phosphatidic acid-mediated mitogenic activation of mTOR signaling. Science 294, 1942-1945. (Pubitemid 33101594)
5. Feng W, Wu H, Chan LN, Zhang M (2007). The Par-3 NTD adopts a PB1-like structure required for Par-3 oligomerization and membrane localization. EMBO J 26, 2786-2796. (Pubitemid 46884272)
6. Feng W, Wu H, Chan LN, Zhang M (2008). Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment. J Biol Chem 283, 23440-23449.
7. Goldstein B, Macara IG (2007). The PAR proteins: fundamental players in animal cell polarization. Dev Cell 13, 609-622. (Pubitemid 350011991)
8. Harris TJ, Peifer M (2005). The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila. J Cell Biol 170, 813-823. (Pubitemid 41242113)
9. Janetopoulos C, Firtel RA (2008). Directional sensing during chemotaxis. FEBS Lett 582, 2075-2085.
10. Krahn MP, Klopfenstein DR, Fischer N, Wodarz A (2010). Membrane targeting of Bazooka/PAR-3 is mediated by direct binding to phosphoinositide lipids. Curr Biol 20, 636-642.
11. LaLonde M et al. (2006). A role for phospholipase D in Drosophila embryonic cellularization. BMC Dev Biol 6, 60.
12. Laprise P, Tepass U (2011). Novel insights into epithelial polarity proteins in Drosophila. Trends Cell Biol 21, 401-408.
13. Limatola C, Barabino B, Nista A, Santoni A (1997). Interleukin 1-beta-induced protein kinase C-zeta activation is mimicked by exogenous phospholipase D. Biochem J 321, 497-501. (Pubitemid 27056500)
14. Limatola C, Schaap D, Moolenaar WH, van Blitterswijk WJ (1994). Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids. Biochem J 304, 1001-1008.
15. Masai I, Okazaki A, Hosoya T, Hotta Y (1993). Drosophila retinal degeneration A gene encodes an eye-specific diacylglycerol kinase with cysteine-rich zinc-finger motifs and ankyrin repeats. Proc Natl Acad Sci USA 90, 11157-11161. (Pubitemid 23354388)
16. McKinley RF, Yu CG, Harris TJ (2012). Assembly of Bazooka polarity landmarks through a multifaceted membrane-association mechanism. J Cell Sci 125, 1177-1190.
17. Morais-de-Sá E, Mirouse V, St Johnston D (2010). aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells. Cell 141, 509-523.
18. Nelson WJ (2003). Adaptation of core mechanisms to generate cell polarity. Nature 422, 766-774.
19. Nishikimi A et al. (2009). Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis. Science 324, 384-387.
20. Nourry C, Grant SG, Borg JP (2003). PDZ domain proteins: plug and play!. Sci STKE 2003, RE7.
21. Raghu P et al. (2009). Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels. J Cell Biol 185, 129-145.
22. Sawyer JK, Choi W, Jung KC, He L, Harris NJ, Peifer M (2011). A contractile actomyosin network linked to adherens junctions by Canoe/afadin helps drive convergent extension. Mol Biol Cell 22, 2491-508.
23. Shao W, Wu J, Chen J, Lee DM, Tishkina A, Harris TJC (2010). A modifier screen for Bazooka/PAR-3 interacting genes in the Drosophila embryo epithelium. PLoS ONE 5, e9938.
24. Shewan A, Eastburn DJ, Mostov K (2011). Phosphoinositides in cell architecture. Cold Spring Harb Perspect Biol 3, a004796.
25. St Johnston D, Ahringer J (2010). Cell polarity in eggs and epithelia: parallels and diversity. Cell 141, 757-774.
26. Stace CL, Ktistakis NT (2006). Phosphatidic acid- and phosphatidylserine-binding proteins. Biochim Biophys Acta 1761, 913-926. (Pubitemid 44332325)
27. Suzuki A, Ohno S (2006). The PAR-aPKC system: lessons in polarity. J Cell Sci 119, 979-987.
28. Tanentzapf G, Tepass U (2003). Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization. Nat Cell Biol 5, 46-52. (Pubitemid 36054328)
29. Tonikian R et al. (2008). A specificity map for the PDZ domain family. PLoS Biol 6, e239.
30. von Stein W, Ramrath A, Grimm A, Muller-Borg M, Wodarz A (2005). Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling. Development 132, 1675-1686. (Pubitemid 40575867)
31. Walther RF, Pichaud F (2010). Crumbs/DaPKC-dependent apical exclusion of Bazooka promotes photoreceptor polarity remodeling. Curr Biol 20, 1065-1074.
32. Wilce MC, Parker MW (1994). Structure and function of glutathione S-transferases. Biochim Biophys Acta 1205, 1-18.
33. Wodarz A, Ramrath A, Grimm A, Knust E (2000). Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts. J Cell Biol 150, 1361-1374.
34. Wu H, Feng W, Chen J, Chan LN, Huang S, Zhang M (2007). PDZ domains of Par-3 as potential phosphoinositide signaling integrators. Mol Cell 28, 886-898. (Pubitemid 350217058)
35. Zhao C, Du G, Skowronek K, Frohman MA, Bar-Sagi D (2007). Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos. Nat Cell Biol 9, 706-712.