An efficient method for the lipase-catalysed resolution and in-line purification of racemic flurbiprofen in a continuous-flow reactor

Journal of Molecular Catalysis B: Enzymatic

Volumn 84, Issue , 2012, Pages 78-82

  Tamborini, Lucia ^a   Romano, Diego ^a   Pinto, Andrea ^a   Bertolani, Arianna ^a   Molinari, Francesco ^a   Conti, Paola ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Catch and release; Enzymatic resolution; Flow reactor; Flurbiprofen; Lipase

Indexed keywords

BATCH METHODS; BUTYL ESTER; CATCH AND RELEASE; CHEMICAL PURITY; CONTINUOUS-FLOW REACTORS; ENANTIOMERIC EXCESS; ENZYMATIC RESOLUTIONS; FLOW REACTORS; FLURBIPROFEN; IN-LINE; KINETIC RESOLUTION;

LIPASES; PURIFICATION;

CATALYSIS;

(R) FLURBIPROFEN; (S) FLURBIPROFEN; FLURBIPROFEN; LIPASE B; UNCLASSIFIED DRUG;

CANDIDA ANTARCTICA; CATALYSIS; CONFERENCE PAPER; CONTINUOUS FLOW REACTOR; DRUG PURIFICATION; ENZYME KINETICS; FEASIBILITY STUDY; FLOW RATE; RACEMIC MIXTURE; REACTION OPTIMIZATION; REACTION TIME; STOICHIOMETRY; TEMPERATURE;

EID: 84866398101     PISSN: 13811177     EISSN: 18733158     Source Type: Journal    
DOI: 10.1016/j.molcatb.2012.02.008     Document Type: Conference Paper

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