LFA-1 expression in a series of colorectal adenocarcinomas

Journal of Gastrointestinal Cancer

Volumn 43, Issue 3, 2012, Pages 462-466

  Papas, Maria G ^a   Karatzas, Pantelis S ^b   Papanikolaou, Ioannis S ^b,c   Karamitopoulou, Evanthia ^a   Delicha, Eumorphia M ^b,c   Adler, Andreas ^c   Triantafyllou, Konstantinos ^b   Thomopoulou, Georgia Heleni ^a   Patsouris, Efstratios ^a   Lazaris, Andreas C ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Colorectal cancer; Integrins; LFA 1; Metastases

Indexed keywords

IMMUNOGLOBULIN G2A ANTIBODY; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER DIAGNOSIS; CANCER GRADING; CANCER INVASION; COLORECTAL CARCINOMA; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; TUMOR LOCALIZATION; TUMOR VOLUME;

ADENOCARCINOMA; AGED; COLORECTAL NEOPLASMS; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPHATIC METASTASIS; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MALE; NEOPLASM GRADING; NEOPLASM INVASIVENESS; PROGNOSIS;

EID: 84866384829     PISSN: 19416628     EISSN: 19416636     Source Type: Journal    
DOI: 10.1007/s12029-011-9341-6     Document Type: Article

References (19)

1. Weitz J, Koch M, Debus J, Höhler T, Galle PR, Büchler MW. Colorectal cancer. Lancet. 2005;365:153-65. doi:10.1016/S0140-6736 (05) 17706-X.
2. Ioana M, Angelescu C, Burada F, Mixich F, Riza A, Dumitrescu T, et al. MMR gene expression pattern in sporadic colorectal cancer. J Gastrointestin Liver Dis. 2010;19:155-9.
3. Skubitz AP. Adhesion molecules. Cancer Treat Res. 2002;107:305-29.
4. Male D. Cell migration and inflammation. In: Roitt I, Brostoff J, Male D, editors. Immunology. 6th ed. London: Mosby; 2001. p. 47-64.
5. Robertson JH, Iga AM, Sales KM, Winslet MC, Seifalian AM. Integrins: a method of early intervention in the treatment of colorectal liver metastases. Curr Pharm Des. 2008;14(3):296-305. doi:10.2174/138161208783413284.
6. Lydyard PM, Grossi CE. Relationship of neoplastic cells with their environment: tumour spread. In: Woolf N, editor. Pathology. Basic and systemic. London: Saunders; 1998. p. 249-60.
7. Berndt U, Philipsen L, Bartsch S, Wiedenmann B, Baumgart DC, Hämmerle M, et al. Systematic high-content proteomic analysis reveals substantial immunologic changes in colorectal cancer. Cancer Res. 2008;68:880-8. doi:10.1158/0008-5472. CAN-07-2923.
8. Luo D, Vermijlen D, Vanderkerken K, Kuppen PJ, Seynaeve C, Eddouks M, et al. Involvement of LFA-1 in hepatic NK cell (pit cell)-mediated cytolysis and apoptosis of colon carcinoma cells. J Hepatol. 1999;31:110-6. doi:10.1016/S0168-8278 (99) 80170-6.
9. Okegawa T, Li Y, Pong RC, Hsieh JT. Cell adhesion proteins as tumor suppressors. J Urol. 2002;167:1836-43. doi:10.1016/S0022-5347 (05) 65245-7.
10. Tanaka Y, Mine S, Figdor CG, Wake A, Hirano H, Tsukada J, et al. Constitutive chemokine production results in activation of leukocyte function-associated antigen-1 on adult T-cell leukemia cells. Blood. 1998;91:3909-19.
11. Hazan RB, Phillips GR, Qiao RF, Norton L, Aaronson SA. Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol. 2000;148:779-90. doi:10.1083/jcb.148.4. 779.
12. Smith A, Stanley P, Jones K, Svensson L, McDowall A, Hogg N. The role of the integrin LFA-1 in T-lymphocyte migration. Immunol Rev. 2007;218:135-46. doi:10.1111/j.1600-065X.2007.00537.x.
13. Hogg N, Laschinger M, Giles K, McDowall A. T-cell integrins: more than just sticking points. J Cell Sci. 2003;116(Pt 23):4695-705. doi:10.1242/jcs. 00876.
14. Kermorgant S, Dessirier V, Lewin MJ, Lehy T. HGF upregulates and modifies subcellular distribution of proteins in colon cancer cell enterocytic differentiation. Am J Physiol Gastrointest Liver Physiol. 2001;281:G1068-80.
15. Fujisaki T, Tanaka Y, Fujii K, Mine S, Saito K, Yamada S, et al. CD44 stimulation induces integrin-mediated adhesion of colon cancer cell lines to endothelial cells by up-regulation of integrins and c-Met and activation of integrins. Cancer Res. 1999;59:4427-34.
16. Mine S, Tanaka Y, Suematu M, Aso M, Fujisaki T, Yamada S, et al. Hepatocyte growth factor is a potent trigger of neutrophil adhesion through rapid activation of lymphocyte function-associated antigen-1. Lab Invest. 1998;78:1395-404.
17. Em M, Zhang J, Siminovitch KA, Takei F. Elucidation of the integrin LFA-1 mediated signaling pathway of actin polarization in natural killer cells. Blood. 2010;116:1272-9. doi:10.1182/blood-2009-12-261487.
18. Schmidmaier R, Baumann P. ANTI-ADHESION evolves to a promising therapeutic concept in oncology. Curr Med Chem. 2008;15:978-90. doi:10.2174/092986708784049667.
19. Papanikolaou IS, Lazaris AC, Kavantzas N, Davaris PS. Minimal expression of the proto-oncogene int-2 encoded protein in a series of colorectal carcinomas. J Gastroenterol Hepatol. 2002;17:1084-6. doi:10.1046/j.1440-1746. 2002.02838.x.