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Volumn 17, Issue 9, 2012, Pages 1171-1179

Controlling embryonic stem cell growth and differentiation by automation: Enhanced and more reliable differentiation for drug discovery

Author keywords

automation; cardiomyocyte differentiation; design of experiment; embryonic stem cells; screening

Indexed keywords

ACTIN; TRANSCRIPTION FACTOR NKX2.5;

EID: 84866363300     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057112452783     Document Type: Article
Times cited : (9)

References (30)
  • 1
    • 0021891053 scopus 로고
    • The in Vitro Development of Blastocyst-Derived Embryonic Stem Cell Lines: Formation of Visceral Yolk Sac, Blood Islands and Myocardium
    • Doetschman T. C., Eistetter H., Katz M., Schmidt W., Kemler R. The In Vitro Development of Blastocyst-Derived Embryonic Stem Cell Lines: Formation of Visceral Yolk Sac, Blood Islands and Myocardium. J. Embryol. Exp. Morphol. 1985 ; 87: 27-45
    • (1985) J. Embryol. Exp. Morphol , vol.87 , pp. 27-45
    • Doetschman, T.C.1    Eistetter, H.2    Katz, M.3    Schmidt, W.4    Kemler, R.5
  • 2
    • 0025841819 scopus 로고
    • Myosin Heavy Chain Gene Expression in Mouse Embryoid Bodies: An in Vitro Developmental Study
    • Sanchez A., Jones W. K., Gulick J., Doetschman T., Robbins J. Myosin Heavy Chain Gene Expression in Mouse Embryoid Bodies: An In Vitro Developmental Study. J. Biol. Chem. 1991 ; 266 (33). 22419-22426
    • (1991) J. Biol. Chem , vol.266 , Issue.33 , pp. 22419-22426
    • Sanchez, A.1    Jones, W.K.2    Gulick, J.3    Doetschman, T.4    Robbins, J.5
  • 3
    • 16744368322 scopus 로고    scopus 로고
    • Differentiating Embryonic Stem Cells into Embryoid Bodies
    • Hopfl G., Gassmann M., Desbaillets I. Differentiating Embryonic Stem Cells into Embryoid Bodies. Methods Mol. Biol. 2004 ; 254: 79-98
    • (2004) Methods Mol. Biol , vol.254 , pp. 79-98
    • Hopfl, G.1    Gassmann, M.2    Desbaillets, I.3
  • 4
    • 0344863075 scopus 로고    scopus 로고
    • The Embryoid Body as a Novel in Vitro Assay System for Antiangiogenic Agents
    • Wartenberg M., Gunther J., Hescheler J., Sauer H. The Embryoid Body as a Novel In Vitro Assay System for Antiangiogenic Agents. Lab. Invest. 1998 ; 78 (10). 1301-1314
    • (1998) Lab. Invest , vol.78 , Issue.10 , pp. 1301-1314
    • Wartenberg, M.1    Gunther, J.2    Hescheler, J.3    Sauer, H.4
  • 8
    • 0345491333 scopus 로고    scopus 로고
    • A Simple Method for Forming Embryoid Body from Mouse Embryonic Stem Cells
    • Kurosawa H., Imamura T., Koike M., Sasaki K., Amano Y. A Simple Method for Forming Embryoid Body from Mouse Embryonic Stem Cells. J. Biosci. Bioeng. 2003 ; 96 (4). 409-411
    • (2003) J. Biosci. Bioeng , vol.96 , Issue.4 , pp. 409-411
    • Kurosawa, H.1    Imamura, T.2    Koike, M.3    Sasaki, K.4    Amano, Y.5
  • 9
    • 62949224898 scopus 로고    scopus 로고
    • Development of Cystic Embryoid Bodies with Visceral Yolk-Sac-Like Structures from Mouse Embryonic Stem Cells Using Low-Adherence 96-Well Plate
    • Yasuda E., Seki Y., Higuchi T., Nakashima F., Noda T., Kurosawa H. Development of Cystic Embryoid Bodies with Visceral Yolk-Sac-Like Structures from Mouse Embryonic Stem Cells Using Low-Adherence 96-Well Plate. J. Biosci. Bioeng. 2009 ; 107 (4). 442-446
    • (2009) J. Biosci. Bioeng , vol.107 , Issue.4 , pp. 442-446
    • Yasuda, E.1    Seki, Y.2    Higuchi, T.3    Nakashima, F.4    Noda, T.5    Kurosawa, H.6
  • 10
    • 23944454402 scopus 로고    scopus 로고
    • Forced Aggregation of Defined Numbers of Human Embryonic Stem Cells into Embryoid Bodies Fosters Robust, Reproducible Hematopoietic Differentiation
    • Ng E. S., Davis R. P., Azzola L., Stanley E. G., Elefanty A. G. Forced Aggregation of Defined Numbers of Human Embryonic Stem Cells into Embryoid Bodies Fosters Robust, Reproducible Hematopoietic Differentiation. Blood. 2005 ; 106 (5). 1601-1603
    • (2005) Blood , vol.106 , Issue.5 , pp. 1601-1603
    • Ng, E.S.1    Davis, R.P.2    Azzola, L.3    Stanley, E.G.4    Elefanty, A.G.5
  • 11
    • 0024245022 scopus 로고
    • Inhibition of Pluripotential Embryonic Stem Cell Differentiation by Purified Polypeptides
    • Smith A. G., Heath J. K., Donaldson D. D., Wong G. G., Moreau J., Stahl M., Rogers D. Inhibition of Pluripotential Embryonic Stem Cell Differentiation by Purified Polypeptides. Nature. 1988 ; 336 (6200). 688-690
    • (1988) Nature , vol.336 , Issue.6200 , pp. 688-690
    • Smith, A.G.1    Heath, J.K.2    Donaldson, D.D.3    Wong, G.G.4    Moreau, J.5    Stahl, M.6    Rogers, D.7
  • 12
    • 0028907753 scopus 로고
    • Embryonic Stem Cells Express Neuronal Properties in Vitro
    • Bain G., Kitchens D., Yao M., Huettner J. E., Gottlieb D. I. Embryonic Stem Cells Express Neuronal Properties In Vitro. Dev. Biol. 1995 ; 168 (2). 342-357
    • (1995) Dev. Biol , vol.168 , Issue.2 , pp. 342-357
    • Bain, G.1    Kitchens, D.2    Yao, M.3    Huettner, J.E.4    Gottlieb, D.I.5
  • 13
    • 0025334260 scopus 로고
    • Mouse Embryonic Stem Cells Express the Cardiac Myosin Heavy Chain Genes during Development in Vitro
    • Robbins J., Gulick J., Sanchez A., Howles P., Doetschman T. Mouse Embryonic Stem Cells Express the Cardiac Myosin Heavy Chain Genes during Development In Vitro. J. Biol. Chem. 1990 ; 265 (20). 11905-11909
    • (1990) J. Biol. Chem , vol.265 , Issue.20 , pp. 11905-11909
    • Robbins, J.1    Gulick, J.2    Sanchez, A.3    Howles, P.4    Doetschman, T.5
  • 14
    • 76749151845 scopus 로고    scopus 로고
    • Prediction of Drug-Induced Cardiotoxicity Using Human Embryonic Stem Cell-Derived Cardiomyocytes
    • Braam S. R., Tertoolen L., van de Stolpe A., Meyer T., Passier R., Mummery C. L. Prediction of Drug-Induced Cardiotoxicity Using Human Embryonic Stem Cell-Derived Cardiomyocytes. Stem Cell Res. 2010 ; 4 (2). 107-116
    • (2010) Stem Cell Res , vol.4 , Issue.2 , pp. 107-116
    • Braam, S.R.1    Tertoolen, L.2    Van De Stolpe, A.3    Meyer, T.4    Passier, R.5    Mummery, C.L.6
  • 15
    • 0032850596 scopus 로고    scopus 로고
    • Bone Morphogenetic Proteins Induce Cardiomyocyte Differentiation through the Mitogen-Activated Protein Kinase Kinase Kinase TAK1 and Cardiac Transcription Factors Csx/Nkx-2.5 and GATA-4
    • Monzen K., Shiojima I., Hiroi Y., Kudoh S., Oka T., Takimoto E., Hayashi D., Hosoda T., Habara-Ohkubo A., Nakaoka T., et al. Bone Morphogenetic Proteins Induce Cardiomyocyte Differentiation through the Mitogen-Activated Protein Kinase Kinase Kinase TAK1 and Cardiac Transcription Factors Csx/Nkx-2.5 and GATA-4. Mol. Cell. Biol. 1999 ; 19 (10). 7096-7105
    • (1999) Mol. Cell. Biol , vol.19 , Issue.10 , pp. 7096-7105
    • Monzen, K.1    Shiojima, I.2    Hiroi, Y.3    Kudoh, S.4    Oka, T.5    Takimoto, E.6    Hayashi, D.7    Hosoda, T.8    Habara-Ohkubo, A.9    Nakaoka, T.10
  • 16
    • 79551597211 scopus 로고    scopus 로고
    • Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines
    • Kattman S. J., Witty A. D., Gagliardi M., Dubois N. C., Niapour M., Hotta A., Ellis J., Keller G. Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines. Cell Stem Cell. 2011 ; 8 (2). 228-240
    • (2011) Cell Stem Cell , vol.8 , Issue.2 , pp. 228-240
    • Kattman, S.J.1    Witty, A.D.2    Gagliardi, M.3    Dubois, N.C.4    Niapour, M.5    Hotta, A.6    Ellis, J.7    Keller, G.8
  • 17
    • 33845928762 scopus 로고    scopus 로고
    • Developmental Stage-Specific Biphasic Roles of Wnt/Beta-Catenin Signaling in Cardiomyogenesis and Hematopoiesis
    • Naito A. T., Shiojima I., Akazawa H., Hidaka K., Morisaki T., Kikuchi A., Komuro I. Developmental Stage-Specific Biphasic Roles of Wnt/Beta-Catenin Signaling in Cardiomyogenesis and Hematopoiesis. Proc. Natl. Acad. Sci. U. S. A. 2006 ; 103 (52). 19812-19817
    • (2006) Proc. Natl. Acad. Sci. U. S. A , vol.103 , Issue.52 , pp. 19812-19817
    • Naito, A.T.1    Shiojima, I.2    Akazawa, H.3    Hidaka, K.4    Morisaki, T.5    Kikuchi, A.6    Komuro, I.7
  • 18
    • 3142765398 scopus 로고    scopus 로고
    • Efficient Cardiomyogenic Differentiation of Embryonic Stem Cell by Fibroblast Growth Factor 2 and Bone Morphogenetic Protein 2
    • Kawai T., Takahashi T., Esaki M., Ushikoshi H., Nagano S., Fujiwara H., Kosai K. Efficient Cardiomyogenic Differentiation of Embryonic Stem Cell by Fibroblast Growth Factor 2 and Bone Morphogenetic Protein 2. Circ. J. 2004 ; 68 (7). 691-702
    • (2004) Circ. J , vol.68 , Issue.7 , pp. 691-702
    • Kawai, T.1    Takahashi, T.2    Esaki, M.3    Ushikoshi, H.4    Nagano, S.5    Fujiwara, H.6    Kosai, K.7
  • 20
    • 0037446546 scopus 로고    scopus 로고
    • Ascorbic Acid Enhances Differentiation of Embryonic Stem Cells into Cardiac Myocytes
    • Takahashi T., Lord B., Schulze P. C., Fryer R. M., Sarang S. S., Gullans S. R., Lee R. T. Ascorbic Acid Enhances Differentiation of Embryonic Stem Cells into Cardiac Myocytes. Circulation. 2003 ; 107 (14). 1912-1916
    • (2003) Circulation , vol.107 , Issue.14 , pp. 1912-1916
    • Takahashi, T.1    Lord, B.2    Schulze, P.C.3    Fryer, R.M.4    Sarang, S.S.5    Gullans, S.R.6    Lee, R.T.7
  • 21
    • 79959457469 scopus 로고    scopus 로고
    • PKG and PKC Are Down-Regulated during Cardiomyocyte Differentiation from Embryonic Stem Cells: Manipulation of These Pathways Enhances Cardiomyocyte Production
    • Mobley S., Shookhof J. M., Foshay K., Park M., Gallicano G. I. PKG and PKC Are Down-Regulated during Cardiomyocyte Differentiation from Embryonic Stem Cells: Manipulation of These Pathways Enhances Cardiomyocyte Production. Stem Cells Int. 2010 ; 2010: 701212
    • (2010) Stem Cells Int , vol.2010 , pp. 701212
    • Mobley, S.1    Shookhof, J.M.2    Foshay, K.3    Park, M.4    Gallicano, G.I.5
  • 22
    • 33645748498 scopus 로고    scopus 로고
    • Regulation of Cardiotrophin-1 Expression in Mouse Embryonic Stem Cells by HIF-1alpha and Intracellular Reactive Oxygen Species
    • Ateghang B., Wartenberg M., Gassmann M., Sauer H. Regulation of Cardiotrophin-1 Expression in Mouse Embryonic Stem Cells by HIF-1alpha and Intracellular Reactive Oxygen Species. J. Cell Sci 119. 2006 ; (Pt. 6). 1043-1052
    • (2006) J. Cell Sci , vol.119 , Issue.PART 6 , pp. 1043-1052
    • Ateghang, B.1    Wartenberg, M.2    Gassmann, M.3    Sauer, H.4
  • 23
    • 0010472032 scopus 로고
    • Monoclonal Antibody Defining a Stage-Specific Mouse Embryonic Antigen (SSEA-1)
    • Solter D., Knowles B. B. Monoclonal Antibody Defining a Stage-Specific Mouse Embryonic Antigen (SSEA-1). Proc. Natl. Acad. Sci. U. S. A. 1978 ; 75 (11). 5565-5569
    • (1978) Proc. Natl. Acad. Sci. U. S. A , vol.75 , Issue.11 , pp. 5565-5569
    • Solter, D.1    Knowles, B.B.2
  • 24
    • 79952050668 scopus 로고    scopus 로고
    • Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A
    • Fujiwara M., Yan P., Otsuji T. G., Narazaki G., Uosaki H., Fukushima H., Kuwahara K., Harada M., Matsuda H., Matsuoka S., et al. Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A. PLoS One. 2011 ; 6 (2). e16734
    • (2011) PLoS One , vol.6 , Issue.2 , pp. 16734
    • Fujiwara, M.1    Yan, P.2    Otsuji, T.G.3    Narazaki, G.4    Uosaki, H.5    Fukushima, H.6    Kuwahara, K.7    Harada, M.8    Matsuda, H.9    Matsuoka, S.10
  • 25
    • 51449091152 scopus 로고    scopus 로고
    • Dorsomorphin, a Selective Small Molecule Inhibitor of BMP Signaling, Promotes Cardiomyogenesis in Embryonic Stem Cells
    • Hao J., Daleo M. A., Murphy C. K., Yu P. B., Ho J. N., Hu J., Peterson R. T., Hatzopoulos A. K., Hong C. C. Dorsomorphin, a Selective Small Molecule Inhibitor of BMP Signaling, Promotes Cardiomyogenesis in Embryonic Stem Cells. PLoS One. 2008 ; 3 (8). e2904
    • (2008) PLoS One , vol.3 , Issue.8 , pp. 2904
    • Hao, J.1    Daleo, M.A.2    Murphy, C.K.3    Yu, P.B.4    Ho, J.N.5    Hu, J.6    Peterson, R.T.7    Hatzopoulos, A.K.8    Hong, C.C.9
  • 27
    • 0027980468 scopus 로고
    • Muscle Cell Differentiation of Embryonic Stem Cells Reflects Myogenesis in Vivo: Developmentally Regulated Expression of Myogenic Determination Genes and Functional Expression of Ionic Currents
    • Rohwedel J., Maltsev V., Bober E., Arnold H. H., Hescheler J., Wobus A. M. Muscle Cell Differentiation of Embryonic Stem Cells Reflects Myogenesis In Vivo: Developmentally Regulated Expression of Myogenic Determination Genes and Functional Expression of Ionic Currents. Dev. Biol. 1994 ; 164 (1). 87-101
    • (1994) Dev. Biol , vol.164 , Issue.1 , pp. 87-101
    • Rohwedel, J.1    Maltsev, V.2    Bober, E.3    Arnold, H.H.4    Hescheler, J.5    Wobus, A.M.6
  • 29
    • 77957922824 scopus 로고    scopus 로고
    • The ROCK Inhibitor Y-27632 Improves Recovery of Human Embryonic Stem Cells after Fluorescence-Activated Cell Sorting with Multiple Cell Surface Markers
    • Emre N., Vidal J. G., Elia J., O'Connor E. D., Paramban R. I., Hefferan M. P., Navarro R., Goldberg D. S., Varki N. M., Marsala M., et al. The ROCK Inhibitor Y-27632 Improves Recovery of Human Embryonic Stem Cells after Fluorescence-Activated Cell Sorting with Multiple Cell Surface Markers. PLoS One. 2010 ; 5 (8). e12148
    • (2010) PLoS One , vol.5 , Issue.8 , pp. 12148
    • Emre, N.1    Vidal, J.G.2    Elia, J.3    O'Connor, E.D.4    Paramban, R.I.5    Hefferan, M.P.6    Navarro, R.7    Goldberg, D.S.8    Varki, N.M.9    Marsala, M.10
  • 30
    • 43149101280 scopus 로고    scopus 로고
    • A Protocol Describing the Use of a Recombinant Protein-Based, Animal Product-Free Medium (APEL) for Human Embryonic Stem Cell Differentiation as Spin Embryoid Bodies
    • Ng E. S., Davis R., Stanley E. G., Elefanty A. G. A Protocol Describing the Use of a Recombinant Protein-Based, Animal Product-Free Medium (APEL) for Human Embryonic Stem Cell Differentiation as Spin Embryoid Bodies. Nat. Protoc. 2008 ; 3 (5). 768-776
    • (2008) Nat. Protoc , vol.3 , Issue.5 , pp. 768-776
    • Ng, E.S.1    Davis, R.2    Stanley, E.G.3    Elefanty, A.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.