Gene expression and collagen fiber micromechanical interactions of the semilunar heart valve interstitial cell

Cellular and Molecular Bioengineering

Volumn 5, Issue 3, 2012, Pages 254-265

  Carruthers, Christopher A ^a   Alfieri, Christina M ^b   Joyce, Erinn M ^a   Watkins, Simon C ^c   Yutzey, Katherine E ^b   Sacks, Michael S ^d  

^a University of Pittsburgh   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d The University of Texas at Austin   (United States)

Author keywords

Cellular deformations; Extracellular matrix; Heart valve remodeling; Mechanobiology; Microstructure; Tissue engineered heart valve; Valve morphology

Indexed keywords

COLLAGEN FIBER; MESSENGER RNA;

ANIMAL TISSUE; AORTA VALVE; ARTICLE; BIOMECHANICS; BLOOD PRESSURE; CELL INTERACTION; CELL STRUCTURE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HEART MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PULMONARY VALVE; QUANTITATIVE STUDY; VALVE INTERSTITIAL CELL;

SUS;

EID: 84866353125     PISSN: 18655025     EISSN: 18655033     Source Type: Journal    
DOI: 10.1007/s12195-012-0230-2     Document Type: Article

References (29)

1. Aikawa, E., P. Whittaker, M. Farber, K. Mendelson, R. F. Padera, M. Aikawa, and F. J. Schoen. Human semi-lunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering. Circulation 113:1344-1352, 2006.
2. Aldous, I., J. Lee, and S. Wells. Differential changes in the molecular stability of collagen from the pulmonary and aortic valves during the fetal-to-neonatal transition. Ann. Biomed. Eng. 38:3000-3009, 2010.
3. Aldous, I. G., S. P. Veres, A. Jahangir, and J. M. Lee. Differences in collagen cross-linking between the four valves of the bovine heart: a possible role in adaptation to mechanical fatigue. Am. J. Physiol. Heart Circ. Physiol. 296:H1898-H1906, 2009.
4. Bouchard-Martel, J., E. Roussel, M. Drolet, M. Arsenault, and J. Couet. Interstitial cells from left-sided heart valves display more calcification potential than from right-sided valves: an in vitro study of porcine valves. J. Heart Valve Dis. 18:421-428, 2009.
5. Chakraborty, S., J. Cheek, B. Sakthivel, B. J. Aronow, and K. E. Yutzey. Shared gene expression profiles in developing heart valves and osteoblast progenitor cells. Physiol. Genomics 35:75-85, 2008.
6. Christie, G. W., and B. G. Barratt-Boyes. Mechanical properties of porcine pulmonary valve leaflets: how do they differ from aortic leaflets? Ann. Thorac. Surg. 60:S195- S199, 1995.
7. Hinton, Jr., R. B., J. Lincoln, G. H. Deutsch, H. Osinska, P. B. Manning, D. W. Benson, and K. E. Yutzey. Extracellular matrix remodeling and organization in developing and diseased aortic valves. Circ. Res. 98:1431-1438, 2006.
8. Hoffman, B. D., and J. C. Crocker. Cell mechanics: dissecting the physical responses of cells to force. Annu. Rev. Biomed. Eng. 11:259-288, 2009.
9. Huang, H. Y., J. Liao, and M. S. Sacks. In situ deformation of the aortic valve interstitial cell nucleus under dia-stolic loading. J. Biomech. Eng. 129:880-889, 2007.
10. Ikhumetse, J., S. Konduri, J. Warnok, Y. Xing, and A. Yoganathan. Cyclic aortic pressure affects the biological properties of porcine pulmonary valve leaflets. J. Heart Valve Dis. 15:295-302, 2006.
11. Joyce, E. M., J. Liao, F. J. Schoen, J. E. Mayer, Jr., and M. S. Sacks. Functional collagen fiber architecture of the pulmonary heart valve cusp. Ann. Thorac. Surg. 87:1240-1249, 2009.
12. Kadner, A., O. Raisky, A. Degandt, D. Tamisier, D. Bonnet, D. Sidi, and P. R. Vouhe. The Ross procedure in infants and young children. Ann. Thorac. Surg. 85:803-808, 2008.
13. Latif, N., P. Sarathchandra, P. M. Taylor, J. Antoniw, and M. H. Yacoub. Localization and pattern of expression of extracellular matrix components in human heart valves. J. Heart Valve Dis. 14:218-227, 2005.
14. Lincoln, J., C. M. Alfieri, and K. E. Yutzey. Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos. Dev. Dyn. 230:239-250, 2004.
15. Merryman, W. D., H. D. Lukoff, R. A. Long, G. C. Eng-elmayr, Jr., R. A. Hopkins, and M. S. Sacks. Synergistic effects of cyclic tension and transforming growth factor-beta1 on the aortic valve myofibroblast. Cardiovasc. Pathol. 16:268-276, 2007.
16. Merryman, W. D., I. Youn, H. D. Lukoff, P. M. Krueger, F. Guilak, R. A. Hopkins, and M. S. Sacks. Correlation between heart valve interstitial cell stiffness and transval-vular pressure: implications for collagen biosynthesis. Am. J. Physiol. Heart Circ. Physiol. 290:H224-H231, 2006.
17. Mirnajafi, A., J. M. Raymer, L. R. McClure, and M. S. Sacks. The flexural rigidity of the aortic valve leaflet in the commissural region. J. Biomech. 39:2966-2973, 2006.
18. Mirnajafi, A., J. M. Raymer, M. J. Scott, and M. S. Sacks. The effects of collagen fiber orientation on the flexural properties of pericardial heterograft biomaterials. Biomaterials 26:795-804, 2005.
19. Rabkin-Aikawa, E., M. Aikawa, M. Farber, J. R. Kratz, G. Garcia-Cardena, N. T. Kouchoukos, M. B. Mitchell, R. A. Jonas, and F. J. Schoen. Clinical pulmonary auto-graft valves: pathologic evidence of adaptive remodeling in the aortic site. J. Thorac. Cardiovasc. Surg. 128:552-561, 2004.
20. Rabkin-Aikawa, E., M. Farber, M. Aikawa, and F. J. Schoen. Dynamic and reversible changes of interstitial cell phenotype during remodeling of cardiac valves. J. Heart Valve Dis. 13:841-847, 2004.
21. Sacks, M. S., W. David Merryman, and D. E. Schmidt. On the biomechanics of heart valve function. J. Biomech. 42:1804-1824, 2009.
22. Screen, H. R., D. A. Lee, D. L. Bader, and J. C. Shelton. Development of a technique to determine strains in tendons using the cell nuclei. Biorheology 40:361-368, 2003.
23. Snider, P., R. B. Hinton, R. A. Moreno-Rodriguez, J. Wang, R. Rogers, A. Lindsley, F. Li, D. A. Ingram, D. Menick, L. Field, A. B. Firulli, J. D. Molkentin, R. Markwald, and S. J. Conway. Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart. Circ. Res. 102: 752-760, 2008.
24. Stella, J. A., J. Liao, Y. Hong, W. David Merryman, W. R. Wagner, and M. S. Sacks. Tissue-to-cellular level deformation coupling in cell micro-integrated elastomeric scaffolds. Biomaterials 29:3228-3236, 2008.
25. Stella, J. A., and M. S. Sacks. On the biaxial mechanical properties of the layers of the aortic valve leaflet. J. Bio-mech. Eng. 129:757-766, 2007.
26. Stephens, E., C. Durst, J. Swanson, K. Grande-Allen, N. Ingels, and D. Miller. Functional coupling of valvular interstitial cells and collagen via α2β1 integrins in the mitral leaflet. Cell. Mol. Bioeng. 3:428-437, 2010.
27. Stephens, E., and K. Grande-Allen. Age-related changes in collagen synthesis and turnover in porcine heart valves. J. Heart Valve Dis. 16:672-682, 2007.
28. Taylor, P. M., P. Batten, N. J. Brand, P. S. Thomas, and M. H. Yacoub. The cardiac valve interstitial cell. Int. J. Biochem. Cell Biol. 35:113-118, 2003.
29. Watkins, S. Immunohistochemistry. In: Current Protocols in Cytometry. New York: John Wiley & Sons, Inc., 2001.