A window into the brain: An in vivo study of the retina in schizophrenia using optical coherence tomography

Psychiatry Research - Neuroimaging

Volumn 203, Issue 1, 2012, Pages 89-94

  Chu, Elvina May Yin ^a   Kolappan, Madhan ^a   Barnes, Thomas R E ^b   Joyce, Eileen M ^a   Ron, Maria A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Biological markers; Macular volume; Retinal nerve fibre layer

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE MARKER; DISEASE SEVERITY; FEMALE; HUMAN; IN VIVO STUDY; LONGITUDINAL STUDY; MALE; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; RETINA MACULA LUTEA; RETINA NERVE CELL; RETINAL NERVE FIBRE LAYER; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA;

ADULT; CASE-CONTROL STUDIES; FEMALE; HUMANS; LINEAR MODELS; MACULA LUTEA; MALE; NERVE FIBERS; ORGAN SIZE; PSYCHOTIC DISORDERS; RETINA; SCHIZOPHRENIA; SEVERITY OF ILLNESS INDEX; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84866303000     PISSN: 09254927     EISSN: 18727506     Source Type: Journal    
DOI: 10.1016/j.pscychresns.2011.08.011     Document Type: Article

References (40)

1. Altintas Ö., Pervin I., Özkan B., Çaglar Y. Correlation between retinal morphological and functional findings and clinical severity in Parkinson's disease. Documenta Ophthalmologica 2007, 116:137-146.
2. Andreasen N.C. Scale for the Assessment of Negative Symptoms (SANS) 1981, University of Iowa, Iowa City, IA.
3. Andreasen N.C. Scale for the Assessment of Positive Symptoms (SAPS) 1983, University of Iowa, Iowa City, IA.
4. Balogh Z., Benedek G., Kéri S. Retinal dysfunctions in schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2007, 32:297-300.
5. Bangalore S.S., Goradia D.D., Nutche J., Diwadkar V.A., Prasad K.M.R., Keshavan M.S. Untreated illness duration correlates with gray matter loss in first-episode psychoses. Neuroreport 2009, 20:729-734.
6. Berisha F., Feke G.T., Trempe C.L., McMeel J.W., Schepens C.L. Retinal abnormalities in early Alzheimer's disease. Investigative Ophthalmology and Visual Science 2007, 48:2285-2289.
7. Brans R.G., van Haren N.E., van Baal G.C., Staal W.G., Schnack H.G., Kahn R.S., Hulshoff Pol H.E. Longitudinal MRI study in schizophrenia patients and their healthy siblings. The British Journal of Psychiatry 2008, 193:422-423.
8. Drake R.E., Osher F.C., Noordsy D.L., Hurlbut S.C., Teague G.B., Beaudett M.S., Malcolm S. Diagnosis of alcohol use disorders in schizophrenia. Schizophrenia Bulletin 1990, 16:57-67.
9. Ellison-Wright I., Bullmore E. Meta-analysis of diffusion tensor imaging studies in schizophrenia. Schizophrenia Research 2009, 108:3-10.
10. Fang A., Qu J., Li L., Ji B. Measurement of retinal nerve fiber layer in primary acute angle closure glaucoma by optical coherence tomography. Journal of Glaucoma 2007, 16:178-184.
11. Fisher J.B., Jacobs D.A., Markowitz C.E., Galetta S.L., Volpe N.J., Nano-Schiavi M.L., Frohman T.C., Calabresi P.A., Maguire M.G., Cutter G.R., Balcer L.J. Relation of visual function to retinal nerve fibre layer thickness in multiple sclerosis. Ophthalmology 2006, 113:324-332.
12. Fujimoto J.G., Huang D., Hee M.R., Ko T., Swanson E.A., Puliafito C.A., Schuman J.S. Physical principles of optical coherence tomography. Optical Coherence Tomography of Ocular Diseases 2004, 677-688. SLACK Inc., New Jersey. J.S. Schuman, C.A. Puliafito, J.G. Fujimoto (Eds.).
13. Gutiérrez-Galve L., Wheeler-Kingshott C.A., Altmann D.R., Price G., Chu E.M., Leeson V.C., Lobo A., Barker G.J., Barnes T.R., Joyce E.M., Ron M.A. Changes in the frontotemporal cortex and cognitive correlates in first-episode psychosis. Biological Psychiatry 2010, 68:51-60.
14. Harrison P.J., Weinberger D.R. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Molecular Psychiatry 2005, 10:40-68.
15. Hébert M., Gagné A.-M., Paradis M.-E., Jomphe V., Roy M.-A., Mérette C., Mazaide M. Retinal response to light in young nonaffected offspring at high genetic risk of neuropsychiatric brain disorders. Biological Psychiatry 2009, 67:270-274.
16. Henderson A.P., Trip S.A., Schlottmann P.G., Altmann D.R., Garway-Heath D.F., Plant G.T., Miller D.H. An investigation of the retinal nerve fibre layer in progressive multiple sclerosis using optical coherence tomography. Brain 2008, 101(Pt 1):277-287.
17. Huang D., Swanson E.A., Lin C.P., Schuman J.S., Stinson W.G., Chang W., Hee M.R., Flotte T., Gregory K., Puliafito C.A., Lin C.P. Optical coherence tomography. Science 1991, 254(5035):1178-1181.
18. Iseri P.K., Altinas O., Tokay T., Yuksel N. Relationship between cognitive impairment and retinal morphological and visual functional abnormalities in Alzheimer Disease. Journal of Neuroophthalmology 2006, 26:18-24.
19. Jablensky A. Epidemiology of schizophrenia: the global burden of disease and disability. European Archives of Psychiatry and Clinical Neuroscience 2000, 250:274-285.
20. Kanaan R.A., Barker G.J., Brammer M., Giampietro V., Shergill S.S., Woolley J.B., Picchioni M., Toulopoulou T., McGuire P. White matter microstructure in schizophrenia: effects of disorder, duration and medication. The British Journal of Psychiatry 2009, 194:236-242.
21. Laird N.M., Ware J.H. Random-effects models for longitudinal data. Biometrics 1982, 38:963-974.
22. Leung C.K., Leung C.Y., Weinreb R.N., Liu S., Ye C., Lai G., Liu N., Pang C.P., Tse K.K., Lam D.S.C. Evaluation of retinal nerve fiber layer progression in glaucoma: a comparison between the fast and the regular retinal nerve fiber layer scans. Ophthalmology 2011, 118:763-767.
23. McGuffin P., Farmer A., Harvey I. A polydiagnostic application of operational criteria in studies of psychotic illness. Development and reliability of the OPCRIT system. Archives of General Psychiatry 1991, 48:764-770.
24. Naismith R.T., Tutlam N.T., Xu J., Shepherd J.B., Klawiter E.C., Song S.-K., Cross A.H. Optical coherence tomography is less sensitive than visual evoked potentials in optic neuritis. Neurology 2009, 73:46-52.
25. Navari S., Dazzan P. Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings. Psychological Medicine 2009, 39:1763-1777.
26. Pantelis C., Velakoulis D., McGorry P.D., Wood S.J., Suckling J., Phillips L.J., Yung A.R., Bullmore E.T., Brewer W.J., Soulsby B., Desmond P., McGuire P. Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison. The Lancet 2003, 361:281-288.
27. Paquet C., Boissonnot M., Roger F., Dighiero P., Gil R., Hugon J. Abnormal retinal thickness in patients with mild cognitive impairment and Alzheimer's disease. Neuroscience Letters 2007, 420:97-99.
28. Pérez-Iglesias R., Tordesillas-Gutiérrez D., Barker G.J., McGuire P.K., Roiz-Santiañez R., Mata I., Marco de Lucas E., Quintana F., Vasquez-Barquero J.L., Crespo-Facorro B. White matter defects in first episode psychosis patients: a voxelwise analysis of diffusion tensor imaging. NeuroImage 2010, 49:199-204.
29. Price G., Cercignani M., Bagary M.S., Barnes T.R.E., Barker G.J., Joyce E.M., Ron M.A. A volumetric MRI and magnetization transfer imaging follow-up study of patients with first-episode schizophrenia. Schizophrenia Research 2006, 87:100-108.
30. Price G., Cercignani M., Parker G.J.M., Altmann D.R., Barnes T.R.E., Barker G.J., Joyce E.M., Ron M.A. Abnormal brain connectivity in first-episode psychosis: a diffusion MRI tractography study of the corpus callosum. NeuroImage 2007, 35:458-466.
31. Ritvo E.R., Creel D., Realmuto G., Crandall A.S. Electroretinograms in autism: a pilot study of b-wave amplitudes. The American Journal of Psychiatry 1988, 145:229-232.
32. Schuman J.S., Pedut-Kloizman T., Hertzmark E., Hee M.R., Wilkins J.R., Coker J.G., Puliafito C.A., Fujimoto J.G., Swanson E.A. Reproducibility of nerve fiber layer thickness measurements using optical coherence tomography. Ophthalmology 1996, 103:1889-1898.
33. Siger M., Dziegielewski K., Jasek L., Bieniek M., Nicpan A., Nawrocki J., Selmaj K. Optical coherence tomography in multiple sclerosis: thickness of the retinal nerve fiber layer as a potential measure of axonal loss and brain atrophy. Journal of Neurology 2008, 255:1555-1560.
34. Sporn A.L., Greenstein D.K., Gogtay N., Jeffries N.O., Lenane M., Gochman P., Clasen L.S., Blumenthal J., Giedd J.N., Rapoport J. Progressive brain volume loss during adolescence in childhood-onset schizophrenia. The American Journal of Psychiatry 2003, 160:2181-2189.
35. Sun D., Stuart G.W., Jenkinson M., Wood S.J., McGorry P.D., Velakoulis D., van Erp T.G., Thompson P.M., Toga A.W., Smith D.J., Cannon T.D., Pantelis C. Brain surface contraction mapped in first-episode schizophrenia: a longitudinal magnetic resonance imaging study. Molecular Psychiatry 2009, 14:976-986.
36. Takahashi T., Wood S.J., Yung A.R., Walterfang M., Phillips L.J., Soulsby B., Kawasaki Y., McGorry P.D., Suzuki M., Velakoulis D., Pantelis C. Superior temporal gyrus volume in antipsychotic-naive people at risk of psychosis. The British Journal of Psychiatry 2010, 196:206-211.
37. Trip S.A., Schlottmann P.G., Jones S.J., Altmann D.R., Garway-Heath D.F., Thompson A.J., Plant G.T., Miller D.H. Retinal nerve fiber layer axonal loss and visual dysfunction in optic neuritis. Annals of Neurology 2005, 58:383-391.
38. van Koolwijk L.M., Desriet D.D., van Duijn C.M., Oostra B.A., van Swieten J.C., de Koning I., Klaver C.C., Lemij H.G. Association of cognitive functioning with retinal nerve fiber layer thickness. Investigative Ophthalmology and Visual Science 2009, 50:4576-4580.
39. Wing J.K., Babor T., Brugha T., Burke J. SCAN: Schedules for Clinical Assessment in Neuropsychiatry. Archives of General Psychiatry 1990, 47:589-593.
40. Witthaus H., Kaufman C., Bohner G., Ozgurday S., Gudlowski Y., Gallinat J., Ruhrmann S., Brune M., Heinz A., Klingebiel R., Juckel G. Gray matter abnormalities in subjects at ultra-high risk for schizophrenia and first-episode schizophrenic patients compared to healthy controls. Psychiatry Research: Neuroimaging 2009, 173:163-169.