Protection of dopaminergic cells by urate requires its accumulation in astrocytes

Journal of Neurochemistry

Volumn 123, Issue 1, 2012, Pages 172-181

  Cipriani, Sara ^a   Desjardins, Cody A ^a   Burdett, Thomas C ^a   Xu, Yuehang ^a   Xu, Kui ^a   Schwarzschild, Michael A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

cell viability; HPLC; MES 23.5 cells; transgenic; transporter; uricase

Indexed keywords

URATE; URATE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASTROCYTE; BIOACCUMULATION; CELL CONTACT; CELL DENSITY; CELL SURVIVAL; CELL VIABILITY; COCULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MICROGLIA; MOUSE; NEUROPROTECTION; NEWBORN; NONHUMAN; OLIGODENDROGLIA; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; ASTROCYTES; CELL SURVIVAL; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HYDROGEN PEROXIDE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NITRITES; OXIDANTS; PROTEIN CARBONYLATION; REACTIVE OXYGEN SPECIES; URATE OXIDASE; URIC ACID;

EID: 84866261719     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07820.x     Document Type: Article

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