메뉴 건너뛰기




Volumn 70, Issue , 2012, Pages 378-387

A novel ultrasensitive LC-MS/MS assay for quantification of intracellular raltegravir in human cell extracts

Author keywords

HIV; Integrase inhibitor; Intracellular; LC MS MS; Raltegravir

Indexed keywords

CELL EXTRACT; RALTEGRAVIR;

EID: 84866261116     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.05.035     Document Type: Article
Times cited : (19)

References (19)
  • 2
    • 84874188724 scopus 로고    scopus 로고
    • Found at: .
    • Found at: http://www.fda.gov/ForConsumers/ByAudience/ForPatientAdvocates/HIVandAIDS%20Activities/ucm124040.htm.
  • 5
    • 33845366857 scopus 로고    scopus 로고
    • Antiretroviral activity, pharmacokinetics, and tolerability of MK-0518, a novel inhibitor of HIV-1 integrase, dosed as monotherapy for 10 days in treatment-naive HIV-1-infected individuals
    • Markowitz M., Morales-Ramirez J.O., Nguyen B.Y., et al. Antiretroviral activity, pharmacokinetics, and tolerability of MK-0518, a novel inhibitor of HIV-1 integrase, dosed as monotherapy for 10 days in treatment-naive HIV-1-infected individuals. J. Acquir. Immune Defic. Syndr. 2006, 43:509-515.
    • (2006) J. Acquir. Immune Defic. Syndr. , vol.43 , pp. 509-515
    • Markowitz, M.1    Morales-Ramirez, J.O.2    Nguyen, B.Y.3
  • 9
    • 84874190364 scopus 로고    scopus 로고
    • Found at: .
    • Found at: http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM070107.pdf.
  • 10
    • 31544436052 scopus 로고    scopus 로고
    • Quantitation of zidovudine triphosphate concentrations from human peripheral blood mononuclear cells by anion exchange solid phase extraction and liquid chromatography-tandem mass spectrometry: an indirect quantitation methodology
    • King T., Bushman L., Anderson P., Delahunty T., Ray M., Fletcher C.V. Quantitation of zidovudine triphosphate concentrations from human peripheral blood mononuclear cells by anion exchange solid phase extraction and liquid chromatography-tandem mass spectrometry: an indirect quantitation methodology. J. Chromatogr. B 2006, 831:248-257.
    • (2006) J. Chromatogr. B , vol.831 , pp. 248-257
    • King, T.1    Bushman, L.2    Anderson, P.3    Delahunty, T.4    Ray, M.5    Fletcher, C.V.6
  • 11
    • 34247253856 scopus 로고    scopus 로고
    • Simultaneous measurement of intracellular triphosphate metabolites of zidovudine, lamivudine and abacavir (carbovir) in human peripheral blood mononuclear cells by combined anion exchange solid phase extraction and LC-MS/MS
    • Robbins B., Poston P., Neal E., Slaughter C., Rodman J. Simultaneous measurement of intracellular triphosphate metabolites of zidovudine, lamivudine and abacavir (carbovir) in human peripheral blood mononuclear cells by combined anion exchange solid phase extraction and LC-MS/MS. J. Chromatogr. B 2007, 850:310-317.
    • (2007) J. Chromatogr. B , vol.850 , pp. 310-317
    • Robbins, B.1    Poston, P.2    Neal, E.3    Slaughter, C.4    Rodman, J.5
  • 12
    • 33750344235 scopus 로고    scopus 로고
    • Liquid chromatography-tandem mass spectrometric determination of tenofovir-diphosphate in human peripheral blood mononuclear cells
    • King T., Bushman L., Anderson P., Kiser J., Ray M., Delahunty T., Fletcher C.V. Liquid chromatography-tandem mass spectrometric determination of tenofovir-diphosphate in human peripheral blood mononuclear cells. J. Chromatogr. B 2006, 843:147-156.
    • (2006) J. Chromatogr. B , vol.843 , pp. 147-156
    • King, T.1    Bushman, L.2    Anderson, P.3    Kiser, J.4    Ray, M.5    Delahunty, T.6    Fletcher, C.V.7
  • 13
    • 0028937676 scopus 로고
    • A human T lymphoid cell variant resistant to the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl)adenine shows a unique combination of a phosphorylation defect and increased efflux of the agent
    • Robbins B., Connelly M., Marshall D., Srinivas R., Fridland A. A human T lymphoid cell variant resistant to the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl)adenine shows a unique combination of a phosphorylation defect and increased efflux of the agent. Mol. Pharmacol. 1995, 47:391-397.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 391-397
    • Robbins, B.1    Connelly, M.2    Marshall, D.3    Srinivas, R.4    Fridland, A.5
  • 14
    • 0017187232 scopus 로고
    • Membrane transport by murine lymphocytes
    • Strauss P., Sheehan J., Kashket E. Membrane transport by murine lymphocytes. J. Exp. Med. 1976, 144:1009-1021.
    • (1976) J. Exp. Med. , vol.144 , pp. 1009-1021
    • Strauss, P.1    Sheehan, J.2    Kashket, E.3
  • 15
    • 0016075161 scopus 로고
    • A rapid technique for separation of thymocytes from suspensions by centrifugation through silicone oil
    • Andreasen P., Schaumburg B., Osterlind K., Vinten J., Gammeltoft S., Gliemann J. A rapid technique for separation of thymocytes from suspensions by centrifugation through silicone oil. Anal. Biochem. 1974, 59:610-616.
    • (1974) Anal. Biochem. , vol.59 , pp. 610-616
    • Andreasen, P.1    Schaumburg, B.2    Osterlind, K.3    Vinten, J.4    Gammeltoft, S.5    Gliemann, J.6
  • 16
    • 79959335730 scopus 로고    scopus 로고
    • Assay for determination of daunorubicin in cancer cells with multidrug resistance phenotype
    • Krumpochova P., Kocurova A., Dolezel P., Mlejnek P. Assay for determination of daunorubicin in cancer cells with multidrug resistance phenotype. J. Chromatogr. B 2011, 879:1875-1880.
    • (2011) J. Chromatogr. B , vol.879 , pp. 1875-1880
    • Krumpochova, P.1    Kocurova, A.2    Dolezel, P.3    Mlejnek, P.4
  • 17
    • 0024319048 scopus 로고
    • Nucleoside uptake and membrane fluidity studies on N-trifluroracetyladriamycin-14-O-hemiadipate-treated human leukemia and lymphoma cells
    • Lameh J., Chuang R., Israel M., Chuang L. Nucleoside uptake and membrane fluidity studies on N-trifluroracetyladriamycin-14-O-hemiadipate-treated human leukemia and lymphoma cells. Cancer Res. 1989, 49:2905-2908.
    • (1989) Cancer Res. , vol.49 , pp. 2905-2908
    • Lameh, J.1    Chuang, R.2    Israel, M.3    Chuang, L.4
  • 18
    • 79956329914 scopus 로고    scopus 로고
    • Evaluation of the mean corpuscular volume of peripheral blood mononuclear cells of HIV patients by a Coulter counter to determine intracellular drug concentrations
    • Simiele M., D'Avolio A., Baietto L., Siccardi M., Sciandra M., Agati S., Cusato J., Bonora S., Di Perri G. Evaluation of the mean corpuscular volume of peripheral blood mononuclear cells of HIV patients by a Coulter counter to determine intracellular drug concentrations. Antimicrob. Agents Chemother. 2011, 55:2976-2978.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 2976-2978
    • Simiele, M.1    D'Avolio, A.2    Baietto, L.3    Siccardi, M.4    Sciandra, M.5    Agati, S.6    Cusato, J.7    Bonora, S.8    Di Perri, G.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.