Effects of combination of thiazolidinediones with melatonin in dexamethasone-induced insulin resistance in mice

Indian Journal of Pharmaceutical Sciences

Volumn 73, Issue 6, 2011, Pages 601-607

  Ghaisas, M ^a   Ahire, Y ^b   Dandawate, P ^c   Gandhi, S ^c   Mule, M ^c  

^a Indira College of Pharmacy   (India)

^b Piramal Enterprises Limited   (India)

^c DR D Y PATIL INSTITUTE OF PHARMACEUTICAL SCIENCES AND RESEARCH   (India)

Author keywords

Insulin resistance; melatonin; thiazolidinediones; type 2 diabetes

Indexed keywords

CATALASE; DEXAMETHASONE; GLITAZONE DERIVATIVE; GLUCOSE; GLUCOSE TRANSPORTER 4; GLUTATHIONE REDUCTASE; MALONALDEHYDE; MELATONIN; PIOGLITAZONE; ROSIGLITAZONE; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HEMIDIAPHRAGM; HYPERGLYCEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID PEROXIDATION; LIVER HOMOGENATE; MONOTHERAPY; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; POLYPHARMACY; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

EID: 84866255250     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.100232     Document Type: Article

References (51)

1. Tahrani AA, Piya MK, Kennedy A, Barnett AH. Glycaemic control in type 2 diabetes: Targets and new therapies. Pharmacol Ther 2010;125:328-61.
2. Qi D, Rodrigues B. Glucocorticoids produce whole body insulin resistance with changes in cardiac metabolism. Am J Physiol Endocrinol Metab 2007;292:654-67.
3. Gholap S, Kar A. Gymnemic acids from Gymnema sylvestre. Potentially regulates dexamethasone-induced hyperglycemia in mice. Pharm Biol 2005;43:192-5.
4. Thomas DM, Udagawa N, Hards DK, Gidsii J, Resret K, Injytt A, et al. Insulin receptor expression in primary and cultured oseoclast like cells. Bone 1998;23:181-6.
5. Lambillotte C, Gilon P, Henquin J. Direct Glucocorticoid Inhibition of Insulin Secretion. J Clin Invest 1999;99:414-23.
6. Dimitriadis G, Leighton B, Parry-Billings M, Sasson S, Young M, Krause U, et al. Effects of glucocorticoid excess on the sensitivity of glucose transport and metabolism to insulin in rat skeletal muscle. Biochem J 2007;321:707-12.
7. Ong JM, Simsolo RB, Saffari B, Kern PA. The regulation of lipoprotein lipase gene expression by dexamethasone in isolated rat adipocytes. Endocrinol 1992;130:2310-6.
8. Rask E, Olsson T, Soderberg S, Andrew RW, Livingstone DE, Johnson O. Tissue-specific dysregulation of cortisol metabolism in human obesity. J Clin Endocrinol Metab 2001;86:1418-21.
9. Buren J, Lai YC, Lundgren M, Eriksson J W, Jensen J. Insulin action and signalling in fat and muscle from dexamethasone-treated rats. Arch Biochem Biophys 2008;474:91-101.
10. Bjelakovic G, Beninati S, Pavlovic D, Kocic G, Jevtovic T, Kamenov B, et al. Dexamethasone and oxidative stress. J Basic Clin Physiol Pharmacol 2007;18:115-27.
11. Ceriello A, Motz E. Is Oxidative Stress the Pathogenic Mechanism Underlying Insulin Resistance, Diabetes, and Cardiovascular Disease? The Common Soil Hypothesis Revisited. Arterioscler Thromb Vasc Biol 2004;24:816-823.
12. Ogihara T, Asano T, Katagiri H, Sakoda H, Anai M, Shojima N, et al. Oxidative stress induces insulin resistance by activating the nuclear factor-κB pathway and disrupting normal subcellular distribution of phosphatidylinositol-3-kinase. Diabetologia 2004;47:794-805.
13. Spiegelman BM. PPAR-γ: Adipogenic regulator and thiazolidinediones receptor. Diabetes 1998;47:507-14.
14. Ruano G, Bernene J, Windemuth A, Bower B, Wencker D, Richard L, et al. Physiogenomic Comparison of Edema and BMI in Patients Receiving Rosiglitazone or Pioglitazone. Clinica Chimica Acta 2008;400:48-55.
15. Reiter RJ, Acuna-Castroviejo D, Tan DX, Burkhardt S. Free radical mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system. Ann NY Acad Sci 2001;939:200-15.
16. Nishida S, Segawa T, Murai I, Nakagawa S. Long-term melatonin administration reduces hyperinsulinemia and improves the altered fatty-acid compositions in type 2 diabetic rats via the restoration of δ-5 desaturase activity. J Pineal Res 2002;32:26-33.
17. Ha E, Yim S, Chung J, Yoon K, Kang I, Cho Y, et al. Melatonin stimulates glucose transport via insulin receptor substrate-1/ phosphatidylinositol 3-kinase pathway in C2C12 murine skeletal muscle cells. J Pineal Res 2006;41:67-72.
18. Kadhim HM, Ismail SH, Hussein KI, Bakir IH, Sahib AS, Khalaf BH, et al. Effects of melatonin and zinc on lipid profile and renal function in type 2 diabetic patients poorly controlled with Metformin. J Pineal Res 2006;41:189-93.
19. Krentz AJ, Bailey CJ. Oral antidiabetic agents: Current role in type 2 diabetes mellitus. Drugs 2005;65:385-411.
20. Ghaisas M, Navghare V, Takawale A, Zope V, Tanwar M, Deshpande A. Effect of Tectona grandis Linn. on dexamethasone-induced insulin resistance in mice. J Ethnopharmacol 2009;122:304-7
21. Gaikwad AB, Viswanad B, Ramarao P. PPAR-γ agonists partially restores hyperglycemia induced aggravation of vascular dysfunction to angiotensin II in thoracic aorta isolated from rats with insulin resistance. Pharmacol Res 2007;55:400-7.
22. Paskaloglu K, Xener G, Ayanoglu-Dulger G. Melatonin treatment protects against diabetes induced functional and biochemical changes in rat aorta and corpus cavernosum. Eur J Pharmacol 2004;499:345-54.
23. Slater TF, Sawyer BC. The stimulatory effect of carbon tetrachloride and other halogenoalkanes or peroxidative reactions in rat liver fraction in vitro. Biochem J 1971;123:805-14.
24. Mishra HP, Fridovich I. Role of superoxide anion in auto-oxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 1972;247:3170-5.
25. Aebi H. Catalase In: Bergmeyer HU. Methods of enzymatic analysis. New York: Academic Press; 1974. p. 673-85.
26. Colowick SP, Kaplan NO, Packer L. Methods in Enzymology. London: Academic Press; 1984. p. 21-125.
27. Ellaman GL. Tissue sulfhydryl group. Arch Biochem Biophys 1959;82:70-7.
28. Prelovsek O, Mars T, Jevsek M, Podbregar M, Grubic Z. High dexamethasone concentration prevents stimulatory effects of TNFalpha and LPS on IL-6 secretion from the precursors of human muscle regeneration. Am J Physiol Regul Integr Comp Physiol 2006;291:R1651-6.
29. Ishida H, Takizawa M, Ozawa S, Nakamichi Y, Yamaguchi S, Katsuta H, et al. Pioglitazone improves insulin secretory capacity and prevents the loss of beta-cell mass in obese diabetic db/db mice: Possible protection of beta cells from oxidative stress. Metabol 2004;53:488-94.
30. Saad MJ, Folli F, Araki E, Hashimoto N, Csermely P, Kahn CR. Regulation of insulin receptor, insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-F442A adipocytes. Effects of differentiation, insulin, and dexamethasone. Mol Endocrinol 1994;8: 545-57.
31. Rondinone CM, Wang LM, Lonnroth P, Wesslau C, Pierce JH, Smith U. Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus PNAS 1997;94:4171-5.
32. Carvalho E, Jansson PA, Axelsen M, Eriksson JW, Huang X, Groop L, et al. Low cellular IRS 1 gene and protein expression predict insulin resistance and NIDDM. FASEB J 1999;13:2173-8.
33. Eriksson J, Lonnroth P, Smith U. Insulin can rapidly increase cell surface insulin binding capacity in rat adipocytes. A novel mechanism related to insulin sensitivity. Diabetes 1992;41:707-14.
34. Kono T, Barham FW. The relationship between the insulin binding capacity of fat cells and the cellular response to insulin. Studies with intact and trypsin-treated fat cells. J Biol Chem 1971;246:6210-6.
35. Pagano G, Cavallo-Perin P, Cassader M, Bruno A, Ozzello A, Masciola P, et al. An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects. J Clin Invest 1983;72:1814-20.
36. Amatruda JM, Livingston JN, Lockwood DH. Cellular mechanisms in selected states of insulin resistance: Human obesity, glucocorticoid excess, and chronic renal failure. Diabetes Metab Rev 985;1:293-317.
37. Young PW, Cawthorne MA, Coyle PJ, Holder JC, Holman GD, Kozka IJ, et al. Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes: Association with increased insulin binding and cell-surface GLUT4 as measured by photoaffinity labeling. Diabetes 1995;44:1087-92.
38. Delaunay F, Khan A, Cintra A, Davani B, Ling ZC, Andersson A, et al. Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids. J Clin Invest 1997;100:2094-8.
39. Czech MP, Corvera S. Signaling mechanisms that regulate glucose transport. J Biol Chem 1999;274:1865-8.
40. Pessin JE, Thurmond DC, Elmendorf JS, Coker KJ, Okada S. Molecular basis of insulin stimulated GLUT4 vesicle trafficking. J Biol Chem 1999;274:2593-6.
41. Charron MJ, Katz EB, Olson AL. GLUT4 gene regulation and manipulation. J Biol Chem 1999;274:3253-6.
42. Kandror KV, Pilch PF. Compartmentalization of protein traffic in insulin-sensitive cells. Am J Physiol 1996;271:E1-14.
43. Rea S, James DE. Moving GLUT4: The biogenesis and trafficking of GLUT4 storage vesicles. Diabetes 1997;46:1667-77.
44. Garvey WT, Huecksteadt TP, Monzon R, Marshall S. Dexamethasone regulates the glucose transport system in primary cultured adipocytes: Different mechanisms of insulin resistance after acute and chronic exposure. Endocrinology 1989;124:2063-73.
45. Kim DS, Kim TW, Park IK, Kang JS, Om AS. Effect of chromium picolinate supplementation on Insulin sensitivity, serum lipid, and body weight in dexamethasone-treated rats. Metabol 2002;51:589-94.
46. Shalam M, Harish MS, Farhana SA. Prevention of dexamethasone and fructose-induced insulin resistance in rats by SH-01D, a herbal preparation. Indian J Pharmacol 2006;38:419-22.
47. Willi SM, Kennedy A, Brant BP, Wallace P, Rogers NL, Garvey WT. Effective use of thiazolidinediones for the treatment of glucocorticoidinduced diabetes. Diabetes Res Clin Pract 2002;58:87-96.
48. Baydas G, Nedzvetsky VS, Nerush PA, Kirichenko SV, Demchenko HM, Reiter RJ. A novel role for melatonin: Regulation of the expression of cell adhesion molecules in the rat hippocampus and cortex. Neurosci Lett 2002;326:109-12.
49. Marfella R, Quagliaro L, Nappo F, Ceriello A, Giugliano D. Acute hyperglycemia induces an oxidative stress in healthy subjects. J Clin Invest 2001;108:635-6.
50. Cam M, Yavuz O, Guven A, Ercan F, Bukan N, Ustundag S. Protective effects of chronic melatonin treatment against renal injury in streptozotocin-induced diabetic rats. J Pineal Res 2003;35:212-20.
51. Dobrian AD, Schriver SD, Khraibi AA, Prewitt RL. Pioglitazone prevents hypertension and reduces oxidative stress in diet-induced obesity. Hypertension 2004;43:48-56.