A validated GC-MS method for the determination and quantification of residual solvents in counterfeit tablets and capsules

Journal of Pharmaceutical and Biomedical Analysis

Volumn 70, Issue , 2012, Pages 64-70

  Deconinck, E ^a   Canfyn, M ^a   Sacre P Y ^a,b   Baudewyns, S ^a   Courselle, P ^a   De Beer, J O ^a  

^a SCIENTIFIC INSTITUTE OF PUBLIC HEALTH   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Counterfeit; GC MS; Headspace; Method validation; Residual solvents

Indexed keywords

2 PROPANOL; ACETIC ACID ETHYL ESTER; ACETONE; ALCOHOL; BENZENE; CARBON TETRACHLORIDE; CHLOROFORM; COUNTERFEIT DRUG; DICHLOROMETHANE; ETHYLBENZENE; SOLVENT; TOLUENE;

ANALYTICAL ERROR; ARTICLE; COLUMN CHROMATOGRAPHY; DRUG CAPSULE; DRUG DETERMINATION; DRUG SCREENING; LIMIT OF DETECTION; MASS FRAGMENTOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TABLET; TEMPERATURE; VALIDATION STUDY;

CALIBRATION; CAPSULES; COUNTERFEIT DRUGS; DRUG CONTAMINATION; FRAUD; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LIMIT OF DETECTION; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SOLVENTS; TABLETS; TEMPERATURE; TIME FACTORS;

EID: 84866249549     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.05.022     Document Type: Article

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