IL-10 Suppression of NK/DC Crosstalk Leads to Poor Priming of MCMV-Specific CD4 T Cells and Prolonged MCMV Persistence

PLoS Pathogens

Volumn 8, Issue 8, 2012, Pages

  Mandaric, Sanja ^a   Walton, Senta M ^a   Rülicke, Thomas ^b   Richter, Kirsten ^a   Girard Madoux, Mathilde J H ^c   Clausen, Björn E ^c   Zurunic, Antonija ^d   Kamanaka, Masahito ^e,f   Flavell, Richard A ^e   Jonjic, Stipan ^d   Oxenius, Annette ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF RIJEKA   (Croatia)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^f Arai Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL KILLER CELL RECEPTOR NKG2D; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CROSS PRESENTATION; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DENDRITIC CELL; IMMUNOMODULATION; INFLAMMATION; INNATE IMMUNITY; MOLECULAR INTERACTION; MOUSE; MURINE CYTOMEGALOVIRUS; NATURAL KILLER CELL; NONHUMAN; PERSISTENT VIRUS INFECTION; VIRUS CELL INTERACTION; VIRUS REPLICATION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; DENDRITIC CELLS; HERPESVIRIDAE INFECTIONS; INTERLEUKIN-10; KILLER CELLS, NATURAL; MICE; MICE, KNOCKOUT; MUROMEGALOVIRUS; VIRUS REPLICATION;

CYTOMEGALOVIRUS; HERPESVIRIDAE; MAIZE CHLOROTIC MOTTLE VIRUS; MUS;

EID: 84866184015     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002846     Document Type: Article

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