Direct visualization of cerebellar nuclei in patients with focal cerebellar lesions and its application for lesion-symptom mapping

NeuroImage

Volumn 63, Issue 3, 2012, Pages 1421-1431

  Maderwald, S ^a   Thurling M ^a   Kuper M ^a   Theysohn, N ^a   Muller O ^a   Beck, A ^b   Aurich, V ^b   Ladd, M E ^a   Timmann, D ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Dentate nuclei; Spatially unbiased atlas template of the cerebellum and brainstem; Subtraction analysis; SUIT; Susceptibility weighted imaging; SWI

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; ATAXIA; BRAIN ISCHEMIA; BRAIN MAPPING; BRAIN SURGERY; CEREBELLUM INJURY; CEREBELLUM NUCLEUS; CEREBELLUM TUMOR; CLINICAL ARTICLE; CONTROLLED STUDY; DENTATE NUCLEUS; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; IMAGE ANALYSIS; IMAGE RECONSTRUCTION; IMAGE SUBTRACTION; MAGNETIC FIELD; MALE; NUCLEAR MAGNETIC RESONANCE SCANNER; PATIENT CODING; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SUSCEPTIBILITY WEIGHTED IMAGING;

ADOLESCENT; ADULT; AGED; BRAIN INJURIES; CEREBELLAR NUCLEI; CEREBELLUM; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; STROKE; YOUNG ADULT;

EID: 84866182463     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2012.07.063     Document Type: Article

References (51)

1. Amarenco P. The spectrum of cerebellar infarctions. Neurology 1991, 41:973-979.
2. Baier B., Bense S., Dieterich M. Are signs of ocular tilt reaction in patients with cerebellar lesions mediated by the dentate nucleus?. Brain 2008, 131:1445-1454.
3. Brandauer B., Hermsdörfer J., Geissendörfer T., Schoch B., Gizewski E.R., Timmann D. Impaired and preserved aspects of independent finger control in patients with cerebellar damage. J. Neurophysiol. 2012, 107:1080-1093.
4. Clement F., Devos D., Moreau C., Coubes P., Destee A., Defebvre L. Neurodegeneration with brain iron accumulation: clinical, radiographic and genetic heterogeneity and corresponding therapeutic options. Acta Neurol. Belg. 2007, 107:26-31.
5. De Stefano N., Dotti M.T., Mortilla M., Federico A. Magnetic resonance imaging and spectroscopic changes in brains of patients with cerebrotendinous xanthomatosis. Brain 2001, 124:121-131.
6. Deoni S.C., Catani M. Visualization of the deep cerebellar nuclei using quantitative T1 and rho magnetic resonance imaging at 3Tesla. NeuroImage 2007, 37:1260-1266.
7. Diedrichsen J. A spatially unbiased atlas template of the human cerebellum. NeuroImage 2006, 33:127-138.
8. Diedrichsen J., Balsters J.H., Flavell J., Cussans E., Ramnani N. A probabilistic MR atlas of the human cerebellum. NeuroImage 2009, 46:39-46.
9. Diedrichsen J., Maderwald S., Küper M., Thürling M., Rabe K., Gizewski E.R., Ladd M.E., Timmann D. Imaging the deep cerebellar nuclei: a probabilistic atlas and normalization procedure. NeuroImage 2011, 54:1786-1794.
10. Dimitrova A., Weber J., Redies C., Kindsvater K., Maschke M., Kolb F.P., Forsting M., Diener H.C., Timmann D. MRI atlas of the human cerebellar nuclei. NeuroImage 2002, 17:240-255.
11. Dimitrova A., Zeljko D., Schwarze F., Maschke M., Gerwig M., Frings M., Beck A., Aurich V., Forsting M., Timmann D. Probabilistic 3D MRI atlas of the human cerebellar dentate/interposed nuclei. NeuroImage 2006, 30:12-25.
12. Donchin O., Rabe K., Diedrichsen J., Lally N., Schoch B., Gizewski E.R., Timmann D. Cerebellar regions involved in adaptation to force field and visuomotor perturbation. J. Neurophysiol. 2012, 107:134-147.
13. Du A.X., Cuzzocreo J.L., Landman B.A., Zee D.S., Prince J.L., Ying S.H. Diffusion tensor imaging reveals disease-specific deep cerebellar nuclear changes in cerebellar degeneration. J. Neurol. 2010, 257:1406-1408.
14. Dum R.P., Strick P.L. An unfolded map of the cerebellar dentate nucleus and its projections to the cerebral cortex. J. Neurophysiol. 2003, 89:634-639.
15. Gans A. Beitrag zur Kenntnis des Aufbaus des Nucleus dentatus aus zwei Teilen, namentlich auf Grund von Untersuchungen der Eisenreaktion. Z. Gesamte Neurol. Psychiatr. 1924, 93:750-755.
16. Haacke E.M., Lai S., Yablonskiy D.A., Lin W. In vivo validation of the BOLD mechanism: a review of signal changes in gradient echo functional MRI in the presence of flow. Int. J. Imaging Syst. Technol. 1995, 6:153-163.
17. Haacke E.M., Xu Y., Cheng Y.C., Reichenbach J.R. Susceptibility weighted imaging (SWI). Magn. Reson. Med. 2004, 52:612-618.
18. Haacke E.M., Mittal S., Wu Z., Neelavalli J., Cheng Y.C. Susceptibility-weighted imaging: technical aspects and clinical applications, part 1. AJNR Am. J. Neuroradiol. 2009, 30:19-30. Review.
19. Heilmaier C., Theysohn J.M., Maderwald S., Kraff O., Ladd M.E., Ladd S.C. A large-scale study on subjective perception of discomfort during 7 and 1.5T MRI examinations. Bioelectromagnetics 2011, 32:610-619.
20. Helms G., Draganski B., Frackowiak R., Ashburner J., Weiskopf N. Improved segmentation of deep brain grey matter structures using magnetization transfer (MT) parameter maps. NeuroImage 2009, 47:194-198.
21. Höpker W. Das Altern des Nucleus dentatus. Z. Alternforsch. 1951, 5:256-277.
22. Ilg.W., Giese M.A., Gizewski E.R., Schoch B., Timmann D. The influence of focal cerebellar lesions on the control and adaptation of gait. Brain 2008, 131:2913-2927.
23. Jansen J., Brodal A. Das Kleinhirn. Handbuch der mikroskopischen Anatomie des Menschen 1958, 1-323. Springer Verlag, Berlin, Göttingen, Heidelberg. W.V. Möllendorff, W. Bargmann (Eds.).
24. Karnath H.O., Himmelbach M., Rorden C. The subcortical anatomy of human spatial neglect: putamen, caudate nucleus and pulvinar. Brain 2002, 125:350-360.
25. Konczak J., Schoch B., Dimitrova A., Gizewski E., Timmann D. Functional recovery of children and adolescents after cerebellar tumour resection. Brain 2005, 128:1428-1441.
26. Küper M., Dimitrova A., Thürling M., Maderwald S., Roths J., Elles H.G., Gizewski E.R., Ladd M.E., Diedrichsen J., Timmann D. Evidence for a motor and a non-motor domain in the human dentate nucleus-an fMRI study. NeuroImage 2011, 54:2612-2622.
27. Küper M., Thürling M., Stefanescu R., Maderwald S., Roths J., Elles H.G., Ladd M.E., Diedrichsen J., Timmann D. Evidence for a motor somatotopy in the cerebellar dentate nucleus-an fMRI study in humans. Hum. Brain Mapp. 2011, (Epub ahead of print).
28. Küper M., Thürling M., Maderwald S., Ladd M.E., Timmann D. Structural and functional magnetic resonance imaging of the human cerebellar nuclei. Cerebellum 2012, 11:314-324.
29. Manni E., Petrosini L. A century of cerebellar somatotopy: a debated representation. Nat. Rev. Neurosci. 2004, 5:241-249. (Review).
30. Marques J.P., van der Zwaag W., Granziera C., Krueger G., Gruetter R. Cerebellar cortical layers: in vivo visualization with structural high-field-strength MR imaging. Radiology 2010, 254:942-948.
31. Marques J.P., Gruetter R., van der Zwaag W. In vivo structural imaging of the cerebellum, the contribution of ultra-high fields. Cerebellum 2010, (Epub ahead of print).
32. Naidich T.P., Duvernoy H.M., Delman B.N., Sorensen A.G., Kollias S.S., Haacke E.M. Duvernoy's atlas of the human brain stem and cerebellum. High-field MRI: Surface Anatomy, Internal Structure, Vascularization and 3D Sectional Anatomy 2009, Springer, Wien.
33. Oldfield R.C. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 1971, 9:97-113.
34. Rauscher A., Sedlacik J., Barth M., Haacke E.M., Reichenbach J.R. Nonnvasive assessment of vascular architecture and function during modulated blood oxygenation using susceptibility weighted magnetic resonance imaging. Magn. Reson. Med. 2005, 54:87-95.
35. Reichenbach J.R., Haacke E.M. High-resolution BOLD venographic imaging: a window into brain function. NMR Biomed. 2001, 14:453-467.
36. Reichenbach J.R., Venkatesan R., Yablonskiy D.A., Thompson M.R., Lai S., Haacke E.M. Theory and application of static field inhomogeneity effects in gradient-echo imaging. J. Magn. Reson. Imaging 1997, 7:266-279. (Review).
37. Rorden C., Karnath H.O. Using human brain lesions to infer function: a relic from a past era in the fMRI age?. Nat. Rev. Neurosci. 2004, 5:813-819.
38. Rorden C., Fridriksson J., Karnath H.O. An evaluation of traditional and novel tools for lesion behavior mapping. NeuroImage 2009, 44:1355-1362.
39. Schlerf J.E., Verstynen T.D., Ivry R.B., Spencer R.M.C. Evidence of a novel somatopic map in the human neocerebellum during complex actions. J. Neurophysiol. 2010, 103:3330-3336.
40. Schmahmann J.D., Doyon J., McDonald D., Holmes C., Lavoie K., Hurwitz A.S., Kabani N., Toga A., Evans A., Petrides M. Three-dimensional MRI atlas of the human cerebellum in proportional stereotaxic space. NeuroImage 1999, 10:233-260.
41. Schoch B., Dimitrova A., Gizewski E.R., Timmann D. Functional localization in the human cerebellum based on voxelwise statistical analysis: a study of 90 patients. NeuroImage 2006, 30:36-51.
42. Spagnolo F., Leopizzi E., Cardamone R., Falautano M., Martinelli V., Comi G., Volonté M.A. Neurodegeneration in the course of Langerhans cell histiocytosis. Neurol. Sci. 2011, 33:605-607.
43. Strick P.L., Dum R.P., Fiez J.A. Cerebellum and nonmotor function. Annu. Rev. Neurosci. 2009, 32:413-434. (Review).
44. Sultan F., Hamodeh S., Baizer J.S. The human dentate nucleus: a complex shape untangled. Neuroscience 2010, 167:965-968.
45. Tatu L., Moulin T., Bogousslavsky J., Duvernoy H. Arterial territories of human brain: brainstem and cerebellum. Neurology 1996, 47:1125-1135.
46. Theysohn J.M., Kraff O., Maderwald S., Barth M., Ladd S.C., Forsting M., Ladd M.E., Gizewski E.R. 7Tesla MRI of microbleeds and white matter lesions as seen in vascular dementia. J. Magn. Reson. Imaging 2011, 33:782-791.
47. Thürling M., Küper M., Stefanescu R., Maderwald S., Gizewski E.R., Ladd M.E., Timmann D. Activation of the dentate nucleus in a verb generation task: a 7T MRI study. NeuroImage 2011, 57:1184-1191.
48. Timmann D., Konczak J., Ilg W., Donchin O., Hermsdörfer J., Gizewski E.R., Schoch B. Current advances in lesion-symptom mapping of the human cerebellum. Neuroscience 2009, 162:836-851. (Review).
49. Timmann D., Küper M., Gizewski E.R., Schoch B., Donchin O. Lesion-symptom mapping of the human cerebellum. Handbook of the Cerebellum and Cerebellar Disorders 2012, Springer Science + Business Media, LLC. 10.1007/978-94-007-1333-8_125. M. Manto, D.L. Gruol, J.D. Schmahmann, N. Koibuchi, F. Rossi (Eds.).
50. Tjoa C.W., Benedict R.H., Weinstock-Guttman B., Fabiano A.J., Bakshi R. MRI T2 hypointensity of the dentate nucleus is related to ambulatory impairment in multiple sclerosis. J. Neurol. Sci. 2005, 234:17-24.
51. Trouillas P., Takayanagi T., Hallett M., Currier R.D., Subramony S.H., Wessel K., Bryer A., Diener H.C., Massaquoi S., Gomez C.M., Coutinho P., Ben Hamida M., Campanella G., Filla A., Schut L., Timann D., Honnorat J., Nighoghossian N., Manyam B. International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome. The Ataxia Neuropharmacology Committee of the World Federation of Neurology. J. Neurol. Sci. 1997, 145:205-211.