Comparison of micro- vs. nanostructured colloidal gelatin gels for sustained delivery of osteogenic proteins: Bone morphogenetic protein-2 and alkaline phosphatase

Biomaterials

Volumn 33, Issue 33, 2012, Pages 8695-8703

  Wang, Huanan ^a,b   Boerman, Otto C ^a   Sariibrahimoglu, Kemal ^a   Li, Yubao ^b   Jansen, John A ^a   Leeuwenburgh, Sander C G ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Colloidal gels; Controlled delivery; Gelatin; Microsphere; Nanosphere; Self healing

Indexed keywords

ALKALINE PHOSPHATASE; BIOMEDICAL APPLICATIONS; BONE MORPHOGENETIC PROTEIN-2; BUILDING BLOCKES; COLLOIDAL GELS; CONTROLLED DELIVERY; CONTROLLED DRUG RELEASE; CROSS-LINKING DENSITY; CROSSLINKED; DRUG RELEASE; GEL STRENGTHS; GELATIN; GELATIN GELS; GELATIN MICROSPHERES; GROWTH FACTOR; IN-VITRO; INJECTABILITY; INJECTABLES; INTERPARTICLE FORCE; MONOLITHIC GELS; NANO-STRUCTURED; OSTEOGENIC PROTEINS; PARTICLE POPULATION; PHYSICOCHEMICAL PROPERTY; REGENERATIVE MEDICINE; SELF-HEALING; THERAPEUTIC PROTEIN; VISCOELASTIC PROPERTIES;

CROSSLINKING; DRUG DELIVERY; ELASTICITY; MEDICAL APPLICATIONS; MICROSPHERES; NANOSPHERES; PHOSPHATASES; PROTEINS; VISCOELASTICITY;

GELS;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; GELATIN; MICROSPHERE; NANOMATERIAL; NANOSPHERE; POLYMER;

ARTICLE; BIODEGRADABILITY; DENSITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; FLOW KINETICS; IN VITRO STUDY; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN SECRETION; VISCOELASTICITY;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; GELATIN; MICROSPHERES; NANOSPHERES; NANOSTRUCTURES;

EID: 84866173418     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.08.024     Document Type: Article

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