메뉴 건너뛰기




Volumn 101, Issue 3, 2012, Pages 202-209

Risk factors for hyperammonemia associated with valproic acid therapy in adult epilepsy patients

Author keywords

Epilepsy; Hepatic enzyme inducer; Hyperammonemia; Logistic regression analysis; Topiramate; Valproic acid

Indexed keywords

ACETAZOLAMIDE; AMMONIA; CARBAMAZEPINE; CLOBAZAM; CLONAZEPAM; DEPAKEN; DIAZEPAM; GABAPENTIN; LAMOTRIGINE; NEUROLEPTIC AGENT; NITRAZEPAM; PHENOBARBITAL; PHENYTOIN; SELENICA; TOPIRAMATE; UNCLASSIFIED DRUG; VALPROIC ACID; ZONISAMIDE;

EID: 84866160237     PISSN: 09201211     EISSN: 18726844     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2012.04.001     Document Type: Article
Times cited : (46)

References (27)
  • 2
    • 79960454020 scopus 로고    scopus 로고
    • New insights on the mechanisms of valproate-induced hyperammonemia: inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA
    • Aires C.C., van Cruchten A., Ijlst L., de Almeida I.T., Duran M., Wanders R.J., Silva M.F. New insights on the mechanisms of valproate-induced hyperammonemia: inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA. J. Hepatol. 2011, 55:426-434.
    • (2011) J. Hepatol. , vol.55 , pp. 426-434
    • Aires, C.C.1    van Cruchten, A.2    Ijlst, L.3    de Almeida, I.T.4    Duran, M.5    Wanders, R.J.6    Silva, M.F.7
  • 3
    • 36048953322 scopus 로고    scopus 로고
    • Hyperammonemia-induced toxicity for the developing central nervous system
    • Cagnon L., Braissant O. Hyperammonemia-induced toxicity for the developing central nervous system. Brain Res. Rev. 2007, 56:183-197.
    • (2007) Brain Res. Rev. , vol.56 , pp. 183-197
    • Cagnon, L.1    Braissant, O.2
  • 4
    • 33847180819 scopus 로고    scopus 로고
    • Case report: valproic Acid and risperidone treatment leading to development of hyperammonemia and mania
    • Carlson T., Reynolds C.A., Caplan R. Case report: valproic Acid and risperidone treatment leading to development of hyperammonemia and mania. J. Am. Acad. Child Adolesc. Psychiatry 2007, 46:356-361.
    • (2007) J. Am. Acad. Child Adolesc. Psychiatry , vol.46 , pp. 356-361
    • Carlson, T.1    Reynolds, C.A.2    Caplan, R.3
  • 5
    • 35748934470 scopus 로고    scopus 로고
    • The measurement of ammonia blood levels in patients taking valproic acid: looking for problems where they do not exist?
    • Chicharro A.V., Kanner A.M. The measurement of ammonia blood levels in patients taking valproic acid: looking for problems where they do not exist?. Epilepsy Behav. 2007, 11:361-366.
    • (2007) Epilepsy Behav. , vol.11 , pp. 361-366
    • Chicharro, A.V.1    Kanner, A.M.2
  • 6
    • 74249120628 scopus 로고    scopus 로고
    • Valproate-induced hyperammonemic encephalopathy and normal liver functions: possible synergism with topiramate
    • Deutsch S.I., Burket J.A., Rosse R.B. Valproate-induced hyperammonemic encephalopathy and normal liver functions: possible synergism with topiramate. Clin. Neuropharmacol. 2009, 32:350-352.
    • (2009) Clin. Neuropharmacol. , vol.32 , pp. 350-352
    • Deutsch, S.I.1    Burket, J.A.2    Rosse, R.B.3
  • 7
    • 0021927494 scopus 로고
    • Chronic valproic acid therapy and incidence of increases in venous plasma ammonia
    • Haidukewych D., John G., Zielinski J.J., Rodin E.A. Chronic valproic acid therapy and incidence of increases in venous plasma ammonia. Ther. Drug Monit. 1985, 7:290-294.
    • (1985) Ther. Drug Monit. , vol.7 , pp. 290-294
    • Haidukewych, D.1    John, G.2    Zielinski, J.J.3    Rodin, E.A.4
  • 8
    • 0033985895 scopus 로고    scopus 로고
    • Valproate-induced hyperammonemic encephalopathy in the presence of topiramate
    • Hamer H.M., Knake S., Schomburg U., Rosenow F. Valproate-induced hyperammonemic encephalopathy in the presence of topiramate. Neurology 2000, 54:230-232.
    • (2000) Neurology , vol.54 , pp. 230-232
    • Hamer, H.M.1    Knake, S.2    Schomburg, U.3    Rosenow, F.4
  • 9
    • 68749120630 scopus 로고    scopus 로고
    • The risk of asymptomatic hyperammonemia in children with idiopathic epilepsy treated with valproate: relationship to blood carnitine status
    • Hamed S.A., Abdella M.M. The risk of asymptomatic hyperammonemia in children with idiopathic epilepsy treated with valproate: relationship to blood carnitine status. Epilepsy Res. 2009, 86:32-41.
    • (2009) Epilepsy Res. , vol.86 , pp. 32-41
    • Hamed, S.A.1    Abdella, M.M.2
  • 10
    • 80155135573 scopus 로고    scopus 로고
    • Transient hyperammonemia in seizures: a prospective study
    • Hung T.Y., Chen C.C., Wang T.L., Su C.F., Wang R.F. Transient hyperammonemia in seizures: a prospective study. Epilepsia 2011, 52:2043-2049.
    • (2011) Epilepsia , vol.52 , pp. 2043-2049
    • Hung, T.Y.1    Chen, C.C.2    Wang, T.L.3    Su, C.F.4    Wang, R.F.5
  • 12
    • 34347223630 scopus 로고    scopus 로고
    • Aggravation of ataxia due to acetazolamide induced hyperammonaemia in episodic ataxia
    • Kim J.M., Ryu W.S., Hwang Y.H., Kim J.S. Aggravation of ataxia due to acetazolamide induced hyperammonaemia in episodic ataxia. J. Neurol. Neurosurg. Psychiatry 2007, 78:771-772.
    • (2007) J. Neurol. Neurosurg. Psychiatry , vol.78 , pp. 771-772
    • Kim, J.M.1    Ryu, W.S.2    Hwang, Y.H.3    Kim, J.S.4
  • 13
    • 52049106877 scopus 로고    scopus 로고
    • Adjunctive topiramate enhances the risk of hypothermia associated with valproic acid therapy
    • Knudsen J.F., Sokol G.H., Flowers C.M. Adjunctive topiramate enhances the risk of hypothermia associated with valproic acid therapy. J. Clin. Pharm. Ther. 2008, 33:513-519.
    • (2008) J. Clin. Pharm. Ther. , vol.33 , pp. 513-519
    • Knudsen, J.F.1    Sokol, G.H.2    Flowers, C.M.3
  • 16
    • 0022651805 scopus 로고
    • Nutritional influence on serum ammonia in young patients receiving sodium valproate
    • Laub M.C. Nutritional influence on serum ammonia in young patients receiving sodium valproate. Epilepsia 1986, 27:55-59.
    • (1986) Epilepsia , vol.27 , pp. 55-59
    • Laub, M.C.1
  • 17
    • 50149083717 scopus 로고    scopus 로고
    • Profiling of astrocyte properties in the hyperammonaemic brain: shedding new light on the pathophysiology of the brain damage in hyperammonaemia
    • Lichter-Konecki U. Profiling of astrocyte properties in the hyperammonaemic brain: shedding new light on the pathophysiology of the brain damage in hyperammonaemia. J. Inherit. Metab. Dis. 2008, 31:492-502.
    • (2008) J. Inherit. Metab. Dis. , vol.31 , pp. 492-502
    • Lichter-Konecki, U.1
  • 18
    • 0036214102 scopus 로고    scopus 로고
    • Topiramate enhances the risk of valproate-associated side effects in three children
    • Longin E., Teich M., Koelfen W., König S. Topiramate enhances the risk of valproate-associated side effects in three children. Epilepsia 2002, 43:451-454.
    • (2002) Epilepsia , vol.43 , pp. 451-454
    • Longin, E.1    Teich, M.2    Koelfen, W.3    König, S.4
  • 19
  • 20
    • 45749150011 scopus 로고    scopus 로고
    • Antiepileptic drugs - best practice guidelines for therapeutic drug monitoring: a position paper by the subcommission on therapeutic drug monitoring. ILAE Commission on Therapeutic Strategies
    • Patsalos P.N., Berry D.J., Bourgeois B.F., Cloyd J.C., Glauser T.A., Johannessen S.I., Leppik I.E., Tomson T., Perucca E. Antiepileptic drugs - best practice guidelines for therapeutic drug monitoring: a position paper by the subcommission on therapeutic drug monitoring. ILAE Commission on Therapeutic Strategies. Epilepsia 2008, 49:1239-1276.
    • (2008) Epilepsia , vol.49 , pp. 1239-1276
    • Patsalos, P.N.1    Berry, D.J.2    Bourgeois, B.F.3    Cloyd, J.C.4    Glauser, T.A.5    Johannessen, S.I.6    Leppik, I.E.7    Tomson, T.8    Perucca, E.9
  • 21
    • 0034018410 scopus 로고    scopus 로고
    • The role of carnitine supplementation during valproic acid therapy
    • Raskind J.Y., El-Chaar G.M. The role of carnitine supplementation during valproic acid therapy. Ann. Pharmacother. 2000, 34:630-638.
    • (2000) Ann. Pharmacother. , vol.34 , pp. 630-638
    • Raskind, J.Y.1    El-Chaar, G.M.2
  • 22
    • 0023020031 scopus 로고
    • Hyperammonaemia and hepatotoxicity during chronic valproate therapy: enhancement by combination with other antiepileptic drugs
    • Ratnaike R.N., Schapel G.J., Purdie G., Rischbieth R.H., Hoffmann S. Hyperammonaemia and hepatotoxicity during chronic valproate therapy: enhancement by combination with other antiepileptic drugs. Br. J. Clin. Pharmacol. 1986, 22:100-103.
    • (1986) Br. J. Clin. Pharmacol. , vol.22 , pp. 100-103
    • Ratnaike, R.N.1    Schapel, G.J.2    Purdie, G.3    Rischbieth, R.H.4    Hoffmann, S.5
  • 24
    • 0033017055 scopus 로고    scopus 로고
    • Carnitine deficiency and hyperammonemia in children receiving valproic acid with and without other anticonvulsant drugs
    • Verrotti A., Greco R., Morgese G., Chiarelli F. Carnitine deficiency and hyperammonemia in children receiving valproic acid with and without other anticonvulsant drugs. Int. J. Clin. Lab. Res. 1999, 29:36-40.
    • (1999) Int. J. Clin. Lab. Res. , vol.29 , pp. 36-40
    • Verrotti, A.1    Greco, R.2    Morgese, G.3    Chiarelli, F.4
  • 26
    • 0021264149 scopus 로고
    • Valproic acid-induced hyperammonemia in mentally retarded adults
    • Williams C.A., Tiefenbach S., McReynolds J.W. Valproic acid-induced hyperammonemia in mentally retarded adults. Neurology 1984, 34:550-553.
    • (1984) Neurology , vol.34 , pp. 550-553
    • Williams, C.A.1    Tiefenbach, S.2    McReynolds, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.