Viral-load-dependent effects of liver injury and regeneration on hepatitis B virus replication in mice

Journal of Virology

Volumn 86, Issue 18, 2012, Pages 9599-9605

  Tian, Yongjun ^a   Chen, Wen Ling ^a   Kuo, Cheng Fu ^a   James Ou, Jing Hsiung ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; HEPATITIS B VIRUS X PROTEIN; HEPATOCYTE NUCLEAR FACTOR 3GAMMA; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEPATITIS B; HEPATITIS B VIRUS X GENE; LIVER INJURY; LIVER REGENERATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRAIN DIFFERENCE; TRANSGENIC MOUSE; VIRUS GENE; VIRUS INHIBITION; VIRUS LOAD; VIRUS PATHOGENESIS; VIRUS REPLICATION;

ANIMALS; BASE SEQUENCE; DNA, VIRAL; HEPATECTOMY; HEPATITIS B VIRUS; HEPATOCYTE NUCLEAR FACTOR 3-GAMMA; HOST-PATHOGEN INTERACTIONS; INTERFERON-ALPHA; INTERFERON-BETA; LIVER; LIVER REGENERATION; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANS-ACTIVATORS; VIRAL LOAD; VIRUS REPLICATION;

HEPATITIS B VIRUS; MUS; MUS MUSCULUS;

EID: 84866154407     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01087-12     Document Type: Article

References (22)

1. Akerman P, et al. 1992. Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy Am. J. Physiol. 263:G579-G585.
2. Campbell JS, et al. 2001. Expression of suppressors of cytokine signaling during liver regeneration J. Clin. Invest. 107:1285-1292.
3. Fausto N, Campbell JS, Riehle KJ. 2006. Liver regeneration Hepatology 43:S45-S53.
4. Fujiyoshi M, Ozaki M. 2011. Molecular mechanisms of liver regeneration and protection for treatment of liver dysfunction and diseases J. Hepatobiliary Pancreat. Sci. 18:13-22.
5. Greene AK, Puder M. 2003. Partial hepatectomy in the mouse: technique and perioperative management J. Investig. Surg. 16:99-102.
6. Guidotti LG, Matzke B, Chisari FV. 1997. Hepatitis B virus replication is cell cycle independent during liver regeneration in transgenic mice J. Virol. 71:4804-4808.
7. Guidotti LG, Matzke B, Schaller H, Chisari FV. 1995. High-level hepatitis B virus replication in transgenic mice J. Virol. 69:6158-6169.
8. He G, Karin M. 2011. NF-κB and STAT3-key players in liver inflammation and cancer Cell Res. 21:159-168.
9. Iwai M, Cui TX, Kitamura H, Saito M, Shimazu T. 2001. Increased secretion of tumour necrosis factor and interleukin 6 from isolated, perfused liver of rats after partial hepatectomy Cytokine 13:60-64.
10. Michalopoulos GK, DeFrances MC. 1997. Liver regeneration Science 276:60-66.
11. Pahlavan PS, Feldmann RE, Jr, Zavos C, Kountouras J. 2006. Prometheus' challenge: molecular, cellular and systemic aspects of liver regeneration J. Surg. Res. 134:238-251.
12. Riehle KJ, et al. 2008. Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3 J. Exp. Med. 205:91-103.
13. Riehle KJ, Dan YY, Campbell JS, Fausto N. 2011. New concepts in liver regeneration J. Gastroenterol. Hepatol. 26(Suppl 1):203-212.
14. Schindler C, Plumlee C. 2008. Inteferons pen the JAK-STAT pathway Semin. Cell Dev. Biol. 19:311-318.
15. Seeger C, Zoulim F, Mason WS. 2007. Hepadnaviruses, p 2977-3029. In Knipe DM, Howley PM (ed), Fields virology, 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
16. Sir D, et al. 2010. The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication Proc. Natl. Acad. Sci. U. S. A. 107:4383-4388.
17. Tian Y, Chen WL, Ou JH. 2011. Effects of interferon-alpha/beta on HBV replication determined by viral load. PLoS Pathog. 7:e1002159. doi:10.1371/journal.ppat.1002159.
18. Trautwein C, Rakemann T, Niehof M, Rose-John S, Manns MP. 1996. Acute-phase response factor, increased binding, and target gene transcription during liver regeneration Gastroenterology 110:1854-1862.
19. Wang H, Ryu WS. 2010. Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion. PLoS Pathog. 6:e1000986. doi:10.1371/journal.ppat.1000986.
20. Xu Z, et al. 2002. Enhancement of hepatitis B virus replication by its X protein in transgenic mice J. Virol. 76:2579-2584.
21. Yang PL, Althage A, Chung J, Chisari FV. 2002. Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection Proc. Natl. Acad. Sci. U. S. A. 99:13825-13830.
22. Zheng Y, Li J, Johnson DL, Ou JH. 2003. Regulation of hepatitis B virus replication by the ras-mitogen-activated protein kinase signaling pathway J. Virol. 77:7707-7712.